Ventricular assist device (VAD)

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Research

Mayo Clinic researchers study left ventricular assist devices (LVADs) and other heart-assist devices such as the total artificial heart. Mayo Clinic researchers participate in clinical trials for ventricular assist devices and publish research findings.

You may have the opportunity to participate in clinical trials. Learn more about cardiovascular research in the Cardiovascular Research Center.

Areas of research have included:

  • Less invasive ways to implant a VAD.
  • Infection risk and treatment after LVAD.
  • Understanding how an LVAD affects blood flow to the heart and rest of the body.
  • How well patients do after LVAD surgery.
  • Prevention and management of VAD complications.
  • How people considering LVAD destination therapy make decisions about their care. This is called shared decision-making intervention.

Publications

See a list of publications about ventricular assist device by Mayo Clinic doctors on PubMed, a service of the National Library of Medicine.

Research Profiles

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By Mayo Clinic Staff

Ventricular assist device care at Mayo Clinic

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AboutCare at Mayo Clinic
May 03, 2023
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  1. Yancy CW, et al. 2017 ACC/AHA/HFSA focused update of the 2013 ACCF/AHA guideline for the management of heart failure. Circulation. 2017; doi:10.1161/CIR.0000000000000509.
  2. Atti V, et al. A comprehensive review of mechanical circulatory support devices. Heart International. 2022; doi:10.17925/HI.2022.16.1.37.
  3. Miller LW, et al. Evolution of left ventricular assist device therapy for advanced heart failure: A review. JAMA Cardiology. 2018; doi:10.1001/jamacardio.2018.0522.
  4. Vieira JL, et al. Mechanical circulatory support devices in advanced heart failure: 2020 and beyond. Progress in Cardiovascular Diseases. 2020; doi:10.1016/j.pcad.2020.09.003.
  5. Libby P, et al., eds. Mechanical circulatory support. In: Braunwald's Heart Disease: A Textbook of Cardiovascular Medicine. 12th ed. Elsevier; 2022. https://www.clinicalkey.com. Accessed Jan. 23, 2023.
  6. Ami TR. Allscripts EPSi. Mayo Clinic. Dec. 24, 2022.
  7. How can I prepare for heart surgery? American Heart Association. https://www.heart.org/en/health-topics/consumer-healthcare/answers-by-heart-fact-sheets/answers-by-heart-fact-sheets-treatments-and-tests. Accessed Jan. 19, 2023.
  8. Office of Patient Education. Heart surgery: Getting ready, surgery and your time in the hospital. Mayo Clinic; 2021.
  9. Brown DL. Ventricular assist device therapy in advanced heart failure. In: Cardiac Intensive Care. 3rd ed. Elsevier. 2019. https://www.clinicalkey.com. Accessed March 27, 2023.
  10. Mancini D. Management of long-term mechanical circulatory support devices. https://www.uptodate.com/contents/search. Accessed March 27, 2023.
  11. O'Horo JC, et al. Left ventricular assist device infections: A systematic review. ASAIO Journal. 2018; doi:10.1097/MAT.0000000000000684.
  12. Allen LA, et al. Effectiveness of an intervention supporting shared decision making for destination therapy left ventricular assist device: The DECIDE-LVAD randomized clinical trial. JAMA. 2018; doi:10.1001/jamainternmed.2017.8713.
  13. Pasrija C, et al. Less invasive left ventricular assist device implantation may reduce right ventricular failure. Interactive Cardiovascular and Thoracic Surgery. 2019; doi:10.1093/icvts/ivz143.
  14. Bachmann JM, et al. Association of cardiac rehabilitation with decreased hospitalizations and mortality after ventricular assist device implantation. JACC Heart Failure. 2018; doi:10.1016/j.jchf.2017.11.002.
  15. Aissaoui N, et al. Understanding left ventricular assist devices. Blood Purification. 2018; doi:10.1159/000491872.
  16. Recommendations for patients and health care providers: HVAD system. U.S. Food and Drug Administration. https://www.fda.gov/medical-devices/cardiovascular-devices/recommendations-patients-and-health-care-providers-hvad-system. Accessed March 28, 2023.
  17. Rosenbaum AN (expert opinion). Mayo Clinic. Feb. 14, 2023.
  18. Dunlay SM (expert opinion). Mayo Clinic. March 12, 2019.
  19. Recalls related to the HVAD system. U.S. Food and Drug Administration. https://www.fda.gov/medical-devices/cardiovascular-devices/recalls-related-hvad-system#recalls. Accessed Feb. 5, 2023.
  20. Rosenbaum AN, et al. Left ventricular hemodynamics and relationship with myocardial recovery and optimization in patients supported on CF-LVAD therapy. Journal of Cardiac Failure. 2022; doi:10.1016/j.cardfail.2021.12.008.

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Ventricular assist device (VAD)