Print Departments and specialties Mayo Clinic has one of the largest and most experienced practices in the United States, with campuses in Arizona, Florida and Minnesota. Staff skilled in dozens of specialties work together to ensure quality care and successful recovery. Departments with related expertise Cancer Care at Mayo Clinic Gastroenterology and Hepatology General Surgery in Phoenix Pediatric Hematology/Oncology Surgical Oncology and Endocrine Surgery in Arizona Trauma, Critical Care and General Surgery in Rochester By Mayo Clinic Staff Request an appointment About July 12, 2022 Print Show references Hoffman R, et al. The spleen and its disorders. In: Hematology: Basic Principles and Practice. 7th ed. Philadelphia, Pa.: Elsevier; 2018. https://www.clinicalkey.com. Accessed June 11, 2018. Barbara Woodward Lips Patient Education Center. Splenectomy: Spleen removal. Rochester, Minn.: Mayo Foundation for Medical Education and Research; 2014. Spleen problems and spleen removal. National Health Service. https://www.nhs.uk/conditions/spleen-problems-and-spleen-removal/. Accessed June 11, 2018. Schrier SL. Approach to the adult with splenomegaly and other splenic disorders. https://www.uptodate.com/contents/search. Accessed June 11, 2018. Related Anemia Enlarged spleen Enlarged spleen (splenomegaly) Hairy cell leukemia Immune thrombocytopenia (ITP) Myelofibrosis Parts of the immune system Ruptured spleen Ruptured spleen Thrombocytopenia Show more related content Products & Services Newsletter: Mayo Clinic Health Letter — Digital Edition Mayo Clinic in Rochester, Minnesota, has been recognized as the best Gastroenterology & GI Surgery hospital in the nation for 2024-2025 by U.S. News & World Report. Learn more about this top honor SplenectomyAboutDoctors&Departments PRC-20395052 Patient Care & Health Information Tests & Procedures Splenectomy