Intraoperative radiation therapy (IORT)

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Departments and specialties

Mayo Clinic has one of the largest and most experienced practices in the United States, with campuses in Arizona, Florida and Minnesota. Staff skilled in dozens of specialties work together to ensure quality care and successful recovery.

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Doctors who perform this procedure

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Displaying 11-16 out of 16 doctors available

  1. Kellie L. Mathis, M.D.

    Kellie L. Mathis, M.D.

    1. General Surgeon
    2. Colon and Rectal Surgeon
    1. Rochester, MN
    Areas of focus:

    Anorectal surgery, Coloanal anastomosis, Colonoscopy, Laparoscopic surgery, Ileoanal anastomosis surgery, Flexible sigm...oidoscopy, Ileostomy surgery, Colostomy, Colorectal surgery, Robotic surgery, Rectal cancer surgery, Colectomy, Rectal prolapse surgery, Proctectomy, Intraoperative radiation therapy, Colon cancer surgery, Pelvic floor dysfunction, Colon cancer, Inflammatory bowel disease, Rectal cancer, Anorectal abnormality, Familial adenomatous polyposis, Ulcerative colitis, Diverticulitis, Constipation, Pouchitis, Colon polyps, Anal fissure, Rectal prolapse, Lynch syndrome, Fistula, Anal fistula, Polyp, Pelvic floor defecatory dysfunction, Carcinoid tumor, Anal cancer, Abscess, Hemorrhoids, Vaginal fistula, Recurrent cancer, Polyposis syndromes, Tubular colon adenoma

  2. Nitin Mishra, M.B.B.S., M.P.H.

    Nitin Mishra, M.B.B.S., M.P.H.

    1. General Surgeon
    2. Colon and Rectal Surgeon
    1. Phoenix, AZ
    Areas of focus:

    Laparoscopic surgery, Colostomy, Colorectal surgery, Robotic surgery, Rectal cancer surgery, Intraoperative radiation t...herapy, Colon cancer surgery, Colon cancer, Inflammatory bowel disease, Rectal cancer, Rectal prolapse, Anal fistula

  3. William G. Rule, M.D.

    William G. Rule, M.D.

    1. Radiation Oncologist
    1. Phoenix, AZ
    Areas of focus:

    Radiation therapy, Proton therapy, Stereotactic body radiotherapy, Intraoperative radiation therapy, Intensity-modulate...d radiation therapy, Colon cancer, Liver cancer, Pancreatic cancer, Neuroendocrine tumor, Multiple myeloma, Rectal cancer, Stomach cancer, Cholangiocarcinoma, Esophageal cancer, Leukemia, Lymphoma, Pancreatic neuroendocrine tumor, Anal cancer, Small bowel cancer, Primary mediastinal large B-cell lymphoma

  4. Yasamin Sharifzadeh-Moghaddam, M.D.

    Yasamin Sharifzadeh-Moghaddam, M.D.

    1. Radiation Oncologist
    1. Rochester, MN
    Areas of focus:

    Radiation therapy, Brachytherapy, Proton therapy, Intraoperative radiation therapy, Proton therapy for prostate cancer,... Radiation therapy for prostate cancer, Osteoarthritis, Colon cancer, Liver cancer, Prostate cancer, Bladder cancer, Pancreatic cancer, Kidney cancer, Rectal cancer, Plantar fasciitis, Cholangiocarcinoma, Esophageal cancer, Dupuytren contracture, Anal cancer, Penile cancer, Urethral cancer

  5. Terence T. Sio, M.D., M.S.

    Terence T. Sio, M.D., M.S.

    1. Radiation Oncologist
    2. Oncologist
    1. Phoenix, AZ
    Areas of focus:

    Radiation therapy, Brain stereotactic radiosurgery, Proton therapy, Stereotactic body radiotherapy, Stereotactic radios...urgery, Intraoperative radiation therapy, Intensity-modulated radiation therapy, Colon cancer, Liver cancer, Hepatocellular carcinoma, Pancreatic cancer, Neuroendocrine tumor, Meningioma, Acoustic neuroma, Rectal cancer, Pituitary tumor, Chordoma, Lung cancer, Brain cancer, Brain tumor, Stomach cancer, Cholangiocarcinoma, Esophageal cancer, Brain metastasis, Glioblastoma, Astrocytoma, Oligodendroglioma, Neurofibromatosis, Glioma, Ependymoma, Spinal cord tumor, Ampullary cancer, Pilocytic astrocytoma, Pancreatic neuroendocrine tumor, Gallbladder cancer, Anal cancer, Spinal tumor, Gastrointestinal stromal tumor, Neurofibroma, Small bowel cancer, Choroid plexus papilloma

  6. Cornelius A. Thiels, D.O., M.B.A.

    Cornelius A. Thiels, D.O., M.B.A.

    1. Hepatobiliary and Pancreas Surgeon
    2. Surgical Oncologist
    1. Rochester, MN
    Areas of focus:

    Cancer treatment, Hepatic artery infusion pump chemotherapy, Whipple procedure, Pancreatectomy, Laparoscopic surgery, S...plenectomy, Cholecystectomy, Gastrectomy, Abdominal surgery, Hyperthermic intraperitoneal chemotherapy, Cytoreductive surgery, Microwave ablation for cancer, Robotic surgery, Rectal cancer surgery, Minimally invasive cancer surgery , Intraoperative radiation therapy, Chemotherapy for colon cancer, Pancreatic enucleation, Liver resection, Minimally invasive pancreas surgery, Minimally invasive liver surgery, Liver tumor, Sarcoma, Liposarcoma, Gastrointestinal stromal tumor, Stage 4 colorectal cancer, Retroperitoneal sarcoma

Research

Mayo Clinic doctors and researchers are studying new ways of using IORT to help more people with cancer.

Cancer research is conducted in coordination with Mayo Clinic Comprehensive Cancer Center. Mayo Clinic Comprehensive Cancer Center receives funding from the National Cancer Institute and is designated as a Comprehensive Cancer Center. This designation recognizes the institution's scientific excellence and multidisciplinary resources focused on cancer prevention, diagnosis and treatment.

Publications

See a list of publications about IORT by Mayo Clinic doctors on PubMed, a service of the National Library of Medicine.

Research Profiles

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By Mayo Clinic Staff

Intraoperative radiation therapy (IORT) care at Mayo Clinic

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AboutCare at Mayo Clinic
April 24, 2026
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  1. Tepper JE, et al., eds. Intraoperative irradiation. In: Gunderson & Tepper's Clinical Radiation Oncology. 5th ed. Elsevier; 2021. https://www.clinicalkey.com. Accessed Nov. 20, 2024.
  2. Jethwa KR, et al. The use of intraoperative radiation therapy in the management of locally recurrent rectal cancer. Seminars in Colon and Rectal Surgery. 2020; doi:10.1016/j.scrs.2020.100763.
  3. Mitin T. Radiation therapy techniques in cancer treatment. https://www.uptodate.com/contents/search. Accessed Nov. 20, 2024.
  4. Medical review (expert opinion). Mayo Clinic. Dec. 16, 2022.
  5. Radiation therapy and you: Support for people with cancer. National Cancer Institute. https://www.cancer.gov/publications/patient-education/radiation-therapy-and-you. Accessed Nov. 20, 2024.

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Intraoperative radiation therapy (IORT)