Departments and specialties

Mayo Clinic has one of the largest and most experienced practices in the United States, with campuses in Arizona, Florida and Minnesota. Staff skilled in dozens of specialties work together to ensure quality care and successful recovery.

Research

Mayo Clinic scientists are actively studying ways to improve bone marrow transplant outcomes. Areas of research include:

  • Expanding the use of haploidentical bone marrow transplant
  • Finding new ways to use bone marrow transplant, including pediatric hemoglobinopathies and inherited metabolic diseases
  • Improving quality of life for bone marrow transplant survivors
  • Preventing and managing graft-versus-host disease (GVHD)
  • Understanding chronic GVHD

Learn more about research in the Bone Marrow Transplant Program.

Cancer research is conducted in coordination with the Mayo Clinic Comprehensive Cancer Center. The Cancer Center receives funding from the National Cancer Institute and is designated as a comprehensive cancer center — recognition for an institution's scientific excellence and multidisciplinary resources focused on cancer prevention, diagnosis and treatment.

Publications

See a list of publications about bone marrow transplant by Mayo Clinic doctors on PubMed, a service of the National Library of Medicine.

Research Profiles

March 28, 2024
  1. AskMayoExpert. Hematopoietic stem cell transplant. Mayo Clinic; 2020.
  2. Hoffman R, et al. Overview and choice of donor of hematopoietic stem cell transplantation. In: Hematology: Basic Principles and Practice. 7th ed. Elsevier; 2018. https://www.clinicalkey.com. Accessed Jan. 28, 2022.
  3. Blood-forming stem cell transplants. National Cancer Institute. http://www.cancer.gov/about-cancer/treatment/types/stem-cell-transplant/stem-cell-fact-sheet. Accessed Jan. 28, 2022.
  4. Majhail NS. How to perform hematopoietic stem cell transplantation. JACC CardioOncology. 2021; doi:10.1016/j.jaccao.2021.09.012.
  5. Diseases treatable by transplants. National Marrow Donor Program. https://bethematch.org/transplant-basics/how-transplants-work/diseases-treatable-by-transplants/. Accessed Jan. 27, 2022.
  6. AskMayoExpert. Cutaneous graft-versus-host disease (adult). Mayo Clinic; 2021.
  7. Blood and marrow stem cell transplantation. Leukemia & Lymphoma Society. https://www.lls.org/resource-center/download-or-order-free-publications. Accessed Jan. 28, 2022.
  8. Chao NJ. Survival, quality-of-life and late complications after hematopoietic cell transplantation in adults. https://www.uptodate.com/contents/search. Accessed Feb. 10, 2022.
  9. Blood and bone marrow transplant. National Heart, Lung, and Blood Institute. https://www.nhlbi.nih.gov/health-topics/blood-and-bone-marrow-transplant. Accessed Jan. 28, 2022.
  10. D'Souza A, et al. Current use of and trends in hematopoietic cell transplantation in the United States. Biology of Blood and Marrow Transplantation. 2020; doi:10.1016/j.bbmt.2020.04.013.
  11. Hematopoietic stem cell transplantation. Merck Manual Professional Version. https://www.merckmanuals.com/professional/immunology-allergic-disorders/transplantation/hematopoietic-stem-cell-transplantation#. Accessed Feb. 10, 2022.
  12. Blood and marrow transplant (BMT): An introduction to allogeneic BMT. Leukemia & Lymphoma Society. https://www.lls.org/resource-center/download-or-order-free-publications. Accessed Jan. 28, 2022.
  13. Participating clinical centers. Primary Immune Deficiency Treatment Consortium. https://www.rarediseasesnetwork.org/cms/pidtc/Learn-More/Participating-Clinical-Centers. Accessed Feb. 18, 2022.
  14. Full membership institutions. Pediatric Transplantation and Cellular Therapy Consortium. http://www.pbmtc.org/about/members/full. Accessed Feb. 18, 2022.
  15. Participating institutions. ECOG-ACRIN Cancer Research Group. https://ecog-acrin.org/participating-institutions. Accessed Feb. 18, 2022.
  16. Mills SD, et al. Bone-marrow transplant in an identical twin. JAMA. 1964; doi:10.1001/jama.1964.03060380005001.
  17. Rashidi A, et al. Outcomes of haploidentical vs matched sibling transplantation for acute myeloid leukemia in first complete remission. Blood Advances. 2019; doi:10.1182/bloodadvances.2019000050.
  18. Ahmed S, et al. Lower graft-versus-host disease and relapse risk in post-transplant cyclophosphamide-based haploidentical versus matched sibling donor reduced-intensity conditioning transplant for Hodgkin Lymphoma. Biology of Blood and Marrow Transplantation. 2019; doi:10.1016/j.bbmt.2019.05.025.
  19. Jain T, et al. Choosing a reduced-intensity conditioning regimen for allogeneic stem cell transplantation, fludarabine/busulfan versus fludarabine melphalan: A systematic review and meta-analysis. Biology of Blood and Marrow Transplantation. 2019; doi:10.1016/j.bbmt.2018.11.016.
  20. Chen YB, et al. Plerixafor alone for the mobilization and transplantation of HLA-matched sibling donor hematopoietic stem cells. Blood Advances. 2019; doi:10.1182/bloodadvances.2018027599.
  21. Ballen KK, et al. Hospital length of stay in the first 100 days after allogeneic hematopoietic cell transplantation for acute leukemia in remission: Comparison among alternative graft sources. Biology of Blood and Marrow Transplantation. 2014; doi:10.1016/j.bbmt.2014.07.021.
  22. Sweeney SK, et al. Tracking embryonic hematopoietic stem cells to the bone marrow: Nanoparticle options to evaluate transplantation efficiency. Stem Cell Research & Therapy. 2018; doi:10.1186/s13287-018-0944-8.
  23. Kumar A, et al. Antithymocyte globulin for graft-versus-host disease prophylaxis: An updated systematic review and meta-analysis. Bone Marrow Transplantation. 2019; doi:10.1038/s41409-018-0393-0.
  24. Graff TM, et al. Safety of outpatient autologous hematopoietic cell transplantation for multiple myeloma and lymphoma. Bone Marrow Transplant. 2015; doi:10.1038/bmt.2015.46.
  25. Braswell Pickering EA. Allscripts EPSi. Mayo Clinic. March 1, 2022.
  26. Search for a FACT accredited organization. Foundation for the Accreditation of Cellular Therapy (FACT). http://accredited.factwebsite.org/. Accessed Feb. 18, 2022.
  27. Transplant center search results. Be The Match. https://bethematch.org/tcdirectory/search/advanced/#mayo/-/-/false/-. Accessed Feb. 18, 2022.
  28. Participating transplant centers. Center for International Blood and Marrow Transplant Research. https://www.cibmtr.org/About/WhoWeAre/Centers/Pages/index.aspx?country=us&state=Minnesota. Accessed Feb. 18, 2022.
  29. Locations. Children's Oncology Group. https://childrensoncologygroup.org/index.php/locations/. Accessed Feb. 18, 2022.