Search Results 831-840 of 16075 for jhajjarcancer

  1. A Study to Assess the MEK Inhibitor Mirdametinib (PD-0325901) in Patients with Neurofibromatosis Type 1 Associated Plexiform Neurofibromas - Mayo Clinic

    The purpose of this study is to evaluate PD-0325901 in the treatment of symptomatic inoperable neurofibromatosis type-1 (NF1)-associated plexiform neurofibromas ...

  2. A Study to Compare Two Surgical Procedures in Women With BRCA1 Mutations to Assess Reduced Risk of Ovarian Cancer - Mayo Clinic

    This trial studies how well two surgical procedures (bilateral salpingectomy and bilateral salpingo-oophorectomy) work in reducing the risk of ovarian cancer ...

  3. Mayo Clinic Comprehensive Cancer Center — Research

    Many hormone receptor positive breast cancers demonstrate overexpression of cyclin D. Cyclin D interacts directly with cyclin-dependent kinases 4 and 6 (CDK4/6) ...

  4. Breast Cancer - eMERGE Genome Informed Risk Assessment - Mayo Clinic Research

    People with high polygenic risk scores are 1.6 to 2.5 times more likely to get breast cancer than are people who aren't in the high-risk category. This estimate ...

  5. A Study to Evaluate Itacitinib for Low Risk Graft-vs-Host Disease (GVHD) - Mayo Clinic

    Itacitinib is an experimental drug with an excellent safety record and appears to have activity as a GVHD treatment. A new blood test can identify patients ...

  6. A Study of Different Heart Imaging Techniques to Detect Amyloidosis Involving the Heart - Mayo Clinic

    Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and ...

  7. Dose Escalation and Expansion Study of GSK525762 in Combination With Fulvestrant in Subjects With Estrogen Receptor Positive (ER+) Breast Cancer - Mayo Clinic

    This is a combination Phase I and Phase II study, with an aim to evaluate the combination of GSK525762 and fulvestrant in women with advanced or metastatic ER+ ...

  8. Characterization of Orthobiologic Agents Used for Point of Care Ultrasound Guided Procedures and Associated Outcomes - Mayo Clinic

    About this study. The purpose of this study is to determine patient and manufacturing factors that influence orthobiologic agent (OBA) product components ...

  9. Optimizing Pancreatic Cancer Management Using Next Generation Imaging and Liquid Biopsy - Mayo Clinic

    We will develop a multivariable model combining ctDNA and FDG PET/MRI biomarkers to predict treatment response and survival. In addition, we will define the ...

  10. DAYBREAK: Phase 2 Study in Patients With Specific Gene Defects in the MC4R Pathway - Mayo Clinic

    About this study. To evaluate the proportion of obese patients with genetic defects in the melanocortin-4 receptor (MC4R) pathway who achieve a clinically ...