Search Results 61-70 of 16990 for Somatic
Clinical and molecular correlates of somatic and germline DDX41 variants in patients and families with myeloid neoplasms. ... Somatic TP53 single ...
These studies contribute to an improved understanding of the mechanisms that underlie the development of physical morbidity and disability in those with somatic ...
Cells constantly pick up mutations after fertilization throughout development and after birth, called somatic mutations. Cells can be tracked through these ...
These changes include somatic mutations, failure in DNA repair, epigenetic signatures including cellular senescence and exhaustion, and organelle dysfunction.
... somatic Homologous Recombination Repair (HRR) gene-mutated mCSPC provides superior effectiveness in improving radiographic progression-free survival (rPFS) ...
Monitoring biological effects of somatic cell genome editing. Nat Rev Genet. 2026 Apr; 27 (4):323-342 Epub 2026 Jan 13. View PubMed; Rees MJ, Dasari S ...
... somatic mutations in tumor- or blood-based genomic profiling. These computational methods detect low-level somatic mutations, which prove difficult but ...
Germline and somatic alterations in these genes are also commonly observed in multiple other cancer types." Dr. Mutter and his colleagues found an up to ...
Prevalence of cytopenia(s) and somatic variants in patients with DDX41 mutant germline predisposition syndrome. Br J Haematol. 2025 Apr; 206 (4):1109-1120 ...
... somatic hypermutation affecting the variable regions of Ig genes, class-switch recombination, and affinity maturation or apoptosis. While these physiologic ...
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