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  1. Defactinib Combined With Pembrolizumab and Gemcitabine in Patients With Advanced Cancer - Mayo Clinic

    About this study. In pancreatic cancer, targeting the tumor microenvironment has become a promising therapeutic strategy. Focal adhesion kinase (FAK) ...

  2. A Study to Evaluate the Safety and Effectiveness of Ustekinumab Induction and Maintenance Therapy in Participants with Moderately to Severely Active Ulcerative Colitis - Mayo Clinic

    About this study. The purpose of this study is to evaluate the effectiveness and safety of continuing ustekinumab as a subcutaneous (injection) maintenance ...

  3. Type 1 Diabetes registry - Mayo Clinic

    Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and ...

  4. Pembrolizumab With Chemotherapy and With/Without MK-4830 for Treating Participants With Ovarian Cancer - Mayo Clinic

    The purpose of this study is to evaluate whether the reduction from baseline in circulating tumor DNA at Cycle 3 (ΔctDNA) is larger in participants receiving MK ...

  5. EEG Study of Cortical Dynamics in Dystonia - Mayo Clinic

    About this study. The aim of this protocol is to design a measurement paradigm that reliably detects EEG oscillatory patterns during movement, relaxation, ...

  6. Randomized, Open Label, Clinical Study of the Targeted Therapy, Palbociclib, to Treat Metastatic Breast Cancer

    About this study. The primary objective of this study is to demonstrate that the combination of palbociclib with anti-HER2 therapy plus endocrine therapy is ...

  7. A Study to Evaluate a New Device for Increasing Accuracy and Efficiency of Image-Guided Stereo EEG Procedures - Mayo Clinic

    The purpose of this study is to evaluate the custom made Stealth Arc Delivery device versus a commercially available device to improve the precision, efficiency ...

  8. A Study to Evaluate Intralesional Injection of Triamcinolone Acetonide to Treat Desmoid Tumors - Mayo Clinic

    The purpose of this study is to determine the response of desmoid tumors to intralesional injections of triamcinolone acetonide. Participation eligibility.

  9. Cellular and Molecular Endocrinology Research - Division of Endocrinology, Diabetes, Metabolism, and Nutrition-Research - Mayo Clinic Research

    Amyloid formation in type 2 diabetes and regulation of growth hormone gene expression; Autoimmune thyroid disease; Bone metabolism; Calcium in atherogenesis ...

  10. Alzheimer's Disease Clinical Trials

    The purpose of this study is to learn more about amyloid and tau burden in the brain of patients with Atypical Alzheimer's Disease and how that burden may ...