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1. An Extension Study to Evaluate the Long-Term Safety and Tolerability of Ubrogepant in the Treatment of Migraine - Mayo Clinic

   Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and ...

2. Study to Evaluate Microbiome Composition and Diversity Signature Using Endoscopic Ultrasound - Mayo Clinic

   About this study. The specific aims of this study are as follows: Aim # 1: To determine the prevalence of pancreas solid tumor intratumoral microbiota, ...

3. Study to Assess the Safety, Tolerability, and Pharmacodynamic (PD) Effects of FRM-0334 in Subjects With Prodromal to Moderate Frontotemporal Dementia With Granulin Mutation - Mayo Clinic

   Study to Assess the Safety, Tolerability, and Pharmacodynamic (PD) Effects of FRM-0334 in Subjects With Prodromal to Moderate Frontotemporal Dementia With ...

4. Study of MK-3475 (Pembrolizumab) in Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma After Treatment With Platinum-based and Cetuximab Therapy (MK-3475-055/KEYNOTE-055) - Mayo Clinic

   This is a study of single-agent pembrolizumab in participants with recurrent and/or metastatic head and neck squamous cell carcinoma (HNSCC) who have progressed ...

5. Evaluation of Extended Wear Infusion Set (EWIS) in Patients With Type 1 Diabetes - Mayo Clinic

   This study is a multi-center, non-randomized, prospective single arm study with type 1 patients with diabetes on insulin pump therapy with Continuous Glucose ...

6. A Study to Evaluate Endoscope-assisted, Minimally-invasive Cortical Access System (MICAS) for Chronic Subdural Evacuation - Mayo Clinic

   The purpose of this study is to evaluate a less-invasive alternative to the currently available method of removing aging blood in the subdural space.

7. Irinotecan Hydrochloride and Temozolomide With Temsirolimus or Monoclonal Antibody Ch14.18 in Treating Younger Patients with Refractory or Relapsed Neuroblastoma - Mayo Clinic

   Temsirolimus may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth. Monoclonal antibodies, such as dinutuximab, may find ...

8. Antihypertensive Treatment of Acute Cerebral Hemorrhage (ATACH-II) - Mayo Clinic

   The specific aims of this study are to: Definitively determine the therapeutic benefit of the intensive treatment relative to the standard treatment in the ...

9. A Study of Swallowing Problems and Aspiration Risks in Elderly Patients with Cervical Spine Fractures - Mayo Clinic

   The purpose of this study is to determine the incidence of swallowing disorders and the risk for aspiration in elderly patients who have cervical spine ...

10. Study to Evaluate the Efficacy and Safety of CUDC-907 in Patients With RR DLBCL, Including Patients With MYC Alterations - Mayo Clinic

    NOTE: For follicular lymphoma transformed to DLBCL (t-FL/DLBCL), single agent non-cytotoxic therapy will not be considered as a line of therapy.