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  1. A Study to Promote Shared Decision Making of Treatment Choices in Patients who have Advanced Kidney Disease - Mayo Clinic

    The purpose of this study is to develop educational materials that will help patients and clinicians talk about treatment options for patients with advanced ...

  2. A Study to Evaluate Cardiotoxicity in Total Hip and Knee Arthroplasty - Mayo Clinic

    The purposes of this study are to determine: the risk of cardiomyopathy and heart failure, and cardiac structure and function in patients with THA and TKA. This ...

  3. SC16LD6.5 in Recurrent Small Cell Lung Cancer - Mayo Clinic

    5 will be assessed by measuring the extent of tumor shrinkage. SC16LD6.5 is an antibody-drug conjugate (ADC). The antibody (SC16) targets a protein that appears ...

  4. Implantation of the HiRes90K™ Advantage Cochlear Implant With HiFocus™ Mid-Scala and Development of a Combined Electric and Acoustic Stimulation Technology in Adults with Partial Deafness - Mayo Clinic

    About this study. The purpose of this feasibility study is to evaluate whether low-frequency acoustic hearing sensitivity can be preserved in newly ...

  5. International Penile Advanced Cancer Trial (International Rare Cancers Initiative Study) - Mayo Clinic

    About this study. This is an international phase III trial, with a Bayesian design, incorporating two sequential randomisations. It efficiently examines a ...

  6. Echocardiographic Measures of Pulmonary Vascular Distensibility and Effects on Lung Diffusing Capacity - Mayo Clinic

    The purpose of this study is to determine if the change in pulmonary vascular compliance with positional changes (upright, supine, and Trendelenburg position) ...

  7. Effect of Bile Acids on Satiety, Cell Function and Body Weight in Patients With Obesity and Abnormal Satiety Phenotype - Mayo Clinic

    The purpose of this study is to evaluate the effect of IC-CBAS 1000 mg BID on EEC function, weight loss, satiety perception, and satiety GI hormones, in ...

  8. Study Evaluating the Safety and Effectiveness of JCARH125 in Subjects with Relapsed and/or Refractory Multiple Myeloma (EVOLVE) - Mayo Clinic

    The study will include a Phase 1 part to determine the recommended dose of JCARH125 in subjects with relapsed and/or refractory multiple myeloma, followed by a ...

  9. Validation of Gene Expression Markers of Renal Allograft Functional Decline - Mayo Clinic

    About this study. Researchers would like to see if it is possible to predict which transplanted kidneys will do better long term based on the gene ...

  10. SAR650984, Pomalidomide and Dexamethasone in Combination in RRMM Patients - Mayo Clinic

    - To assess the relationship between clinical effects (adverse event [AE] and/or tumor response) and CD38 receptor density at baseline (Part A). Participation ...