Search Results 31-40 of 16368 for senescent cells senolytic
... senescent cells in the processes of aging and cancer. Cellular senescence, a state of irreversible cell cycle arrest that limits the ability of cells to ...
LeBrasseur and colleagues demonstrated that the SASP contributes to tissue dysfunction by inducing paracrine senescence and inflammation, stem cell dysfunction, ...
“Additionally, we have developed a new senescent cell transplantation model that allows us to test whether clearing senescent cells alleviates or delays ...
Researchers in the Regenerative Neurosurgery and Neuro-Oncology Lab are studying how identify and potentially kill residual senescent tumor cells after ...
van Deursen developed a facility to create mouse models of human disease. He unexpectedly hit upon a major breakthrough — one that researchers had been trying ...
With further research, senolytic therapy may be considered for a future role in treatment of heart failure, the study concludes. "Senescence and aging are well- ...
Senescent cells are malfunctioning cells that build up as people age or as the result of chronic diseases. Once these cells form, they can contribute to ...
... cells and senolytic drugs ... Cellular senescence leads cells to acquire a senescence ... Senolytic compounds target pro-survival pathways in senescent cells, and ...
Obese mice lose anxiety when 'zombie cells' exit their brain (Mayo Clinic News Network); Connecting Senescent Cells to Obesity and Anxiety (NIH Director's Blog).
Now researchers are looking at the toxic proteins released by senescent cells, called the senescence-associated secretory phenotype, or SASP. They are ...
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