Search Results 291-300 of 7938 for TNF

  1. A Study Using Targeted Inhibitors to Treat Specific Tumor Mutations in Patients with Meningiomas - Mayo Clinic

    This phase II trial studies how well vismodegib and focal adhesion kinase (FAK) inhibitor GSK2256098 work in treating patients with meningiomas that may have ...

  2. Gastrointestinal Stromal Tumor Clinical Trials - Mayo Clinic Research

    The purpose of this study is to investigate the effect of Avapritinib on the pharmacokinetics of Midazolam in patients with unresectable or metastatic ...

  3. Sapanisertib in Treating Patients With Metastatic or Refractory Pancreatic Neuroendocrine Tumor That Cannot Be Removed by Surgery - Mayo Clinic

    About this study. This phase II trial studies how well sapanisertib works in treating patients with pancreatic neuroendocrine tumor that has spread to other ...

  4. Evaluation of N Latex Beta Trace Protein on BN™ Systems as eGFR and RKF Marker - Mayo Clinic

    About this study. The purpose of this study is to test specific analytical performance characteristics of the beta trace protein (BTP) assay on the BN ...

  5. A Study to Test the Effectiveness of Two Immunotherapy Drugs (Nivolumab and Ipilimumab) with One Anti-cancer Targeted Drug (Cabozantinib) for Rare Genitourinary Tumors - Mayo Clinic

    Cabozantinib may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth. Immunotherapy with monoclonal antibodies, such as ...

  6. A Study to Evaluate HKI-272 and Capecitabine for HER2-Positive Breast Cancer and Brain Metastases - Mayo Clinic

    The purpose of this research study is to determine how well neratinib works in treating breast cancer that has spread to the brain. Neratinib is a recently ...

  7. A Study to Compare Cabozantinib versus Sunitinib to Treat Metastatic Variant Histology Renal Cell Carcinoma Patients - Mayo Clinic

    About this study. The purpose of this investigational study is to compare the safety and effectiveness of cabozantinib and sunitinib when given to patients ...

  8. Study of Pembrolizumab With Ipilimumab or Placebo in Participants with Untreated Metastatic Non-small Cell Lung Cancer - Mayo Clinic

    The primary hypothesis of this study is that overall survival (OS) and/or progression-free survival (PFS) is prolonged in participants who receive pembrolizumab ...

  9. Myelofibrosis Clinical Trials - Mayo Clinic Research

    ... TNF-α apoptotic pathway, 2)alternative splicing, tipping the balance towards pro-apoptotic as opposed to anti-apoptotic isoforms, and 3)inhibition of the ...

  10. A Study to Evaluate DNA Evaluation of Fragments for Early Interception - Lung Cancer Training Study - Mayo Clinic

    The purpose of this study is train and test classifiers for lung cancer detection using the DELFI assay and other biomarker and clinical features. Participation ...