Search Results 21-30 of 16087 for senescent cells senolytic
The purpose of this study is to test whether intermittent senolytic therapy reduces markers of biological age and improves bone turnover markers and skeletal ...
Zhu's research is to unravel the mechanisms of senescent cell involvement in these diseases and develop senolytic drugs to precisely target senescent cells.
... senescent cells drive plaque formation in animal models of ... senolytic medicines, including small molecules that selectively eliminate senescent cells.
... senescence-associated secretory phenotype, where senescent cells release bioactive molecules. ... The use of senolytic drugs to selectively eliminate senescent ...
... senolytic, a class of compounds that destroys senescent cells. Cellular senescence describes a specific type of cell fate wherein afflicted cells become cell ...
Called senescent cells, these cellular zombies have been ordered by the body to stop dividing but continue to pump out inflammatory signals and disrupt the ...
... senescent cells and lessen some of the symptoms. The findings appear in the journal Aging Cell. Two major indicators of cellular senescence that can be ...
van Deursen developed a facility to create mouse models of human disease. He unexpectedly hit upon a major breakthrough — one that researchers had been trying ...
LeBrasseur and colleagues demonstrated that the SASP contributes to tissue dysfunction by inducing paracrine senescence and inflammation, stem cell dysfunction, ...
Senescent cells are malfunctioning cells that build up as people age or as the result of chronic diseases. Once these cells form, they can contribute to ...
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