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1. Phase 1b Open-Label Study of PEGPH20 With Pembrolizumab - Mayo Clinic

   This is a phase 1b study evaluating a combination of PEGPH20 and pembrolizumab in hyaluronan-high (HA-high) subjects with relapsed/refractory Non-Small Cell ...

2. A Study to Evaluate the Safety and Feasibility of Intra-articular Transplantation of Autologous Adipose Derived Stromal Vascular Fraction (SVF) for Treatment of Osteoarthritis of the Knee - Mayo Clinic

   The purpose of this study is to determine the safety and feasibility of autologous, adipose derived stromal vascular fraction injections in the treatment of ...

3. A Study to Analyze the Effects of Buprenorphine on Hyperalgesia in Patients with Opioid Use Disorder - Mayo Clinic

   The purpose of this study is to investigate the effects of buprenorphine on hyperalgesia (HP) perception in adults undergoing treatment for opioid use disorder ...

4. A Quality of Life Assessment of Patients with Biliary Obstruction Undergoing Endoscopic or Percutaneous Drainage - Mayo Clinic

   Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and ...

5. A Study to Evaluate ELU001 in Patients With Solid Tumors That Overexpress Folate Receptor Alpha (FRα) - Mayo Clinic

   The primary purpose of Part 1 (dose escalation) of this study is to establish the MTD and/or RP2D of ELU001 in subjects who have advanced, recurrent or ...

6. Onvansertib for the Treatment of Recurrent or Refractory Chronic Myelomonocytic Leukemia - Mayo Clinic

   Onvansertib is a drug that binds to and inhibits an enzyme called PLK1, preventing cancer cell proliferation and causing cell death. Participation eligibility.

7. Dabrafenib Combined With Trametinib After Radiation Therapy in Treating Patients With Newly-Diagnosed High-Grade Glioma - Mayo Clinic

   About this study. The purpose of this study is to estimate the event-free survival (EFS) distribution for newly-diagnosed patients with BRAFV600-mutant ...

8. Bleeding in Hospitalized Patients with Liver Disease - Mayo Clinic

   The primary purpose of this study is to develop an understanding of the prevalence, characteristics, and outcomes of major bleeding and clinically relevant non- ...

9. A Study to Develop Technology for Increasing In-Seat Movement to Prevent Sitting-Acquired Pressure Injuries in Wheelchair Users - Mayo Clinic

   The purpose of this study is to provide wheelchair users with personal-use technology that provides effective feedback to increase movement to prevent pressure ...

10. Study of Xavier Electromyographic Wheelchair Control for Limited Mobility Patients - Mayo Clinic

    About this study. The purpose of this study is to assess the functional mobility and self-reported satisfaction with the Xavier electromyography hands-free ...