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  1. Efficacy and Safety of IV Rigosertib in MDS Patients With Excess Blasts Progressing After Azacitidine or Decitabine - Mayo Clinic

    This study will examine the effect intravenously administered rigosertib has on the relationship between bone marrow blasts response and overall survival in ...

  2. Use of Tamoxifen in Systemic Mastocytosis - Mayo Clinic

    About this study. In this study, the investigators will determine the utility of Tamoxifen, a non-cytotoxic agent, to improve quality of life, ...

  3. A Population-Based Analysis of the Prevalence and Risk Factors for Pentosan Polysulfate Maculopathy - Mayo Clinic

    About this study. The purpose of this study is to to address the current lack of a true prevalent diagnosis of interstitial cystitis and perform outreach to ...

  4. Identifying Physical Function Trajectories and Biomarkers after Kidney Transplantation - Mayo Clinic

    The aims of this study are to identify frailty trajectories and biomarkers of frailty after kidney transplantation. Subjects will be followed beginning ...

  5. A Study of the Effect of Vedolizumab in Conjunction with Structured Semi-Vegetarian Diet on the Treatment of Ulcerative Colitis - Mayo Clinic

    The purpose of this study is to assess the integrated effect of normalization of intestinal dysbiosis through a structured semi-vegetarian dietary intervention ...

  6. A Study of Magnetic Resonance Elastography to Measure Heart Muscle Stiffness in Patients with Hypertrophic Cardiomyopathy - Mayo Clinic

    The purpose of this study is to use magnetic resonance elastography to assess heart muscle stiffness in patients with hypertrophic cardiomyopathy compared to ...

  7. Phase 1/2 Dose Escalation and Efficacy Study of Anti-CD38 Monoclonal Antibody in Patients With Selected CD38+ Hematological Malignancies - Mayo Clinic

    About this study. Primary Objective: Phase 1: To determine the maximum tolerated dose (MTD)/maximum administered dose (MAD) of SAR650984 (Isatuximab).

  8. Descriptive Analysis of Gut Microbiome Alterations in Hyperoxaluric Patients - Mayo Clinic

    About this study. To characterize the microbiome in 4 groups of subjects (primary hyperoxaluria type I (PH1), idiopathic CaOx stone, enteric hyperoxaluria ...

  9. Cardiac Rehabilitation in Heart Failure With Mitochondrial Adaptation To High-intensity Interval Training - Mayo Clinic

    About this study. The purpose of this study is to examine PRO-HIIT compared with CON-HIIT on effectiveness for improving locomotor muscle mitochondrial ...

  10. Lab Draw Associated Blood Loss in Euvolemic Hemodynamically Stable Surgical ICU Patients - Mayo Clinic

    The purpose of this study is to determine the average volume of blood drawn in a 24 hour period in a hemodynamically stable, euvolemic Trauma/Surgical ICU ...