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  1. A Study to Evaluate Sacubitril-Valsartan for Left Ventricular Reverse Remodeling in Adults with Congenital Heart Abnormality - Mayo Clinic

    The purpose of this study is to determine the optimal medical therapy to improve left ventricular (LV) function. Improvement in LV function has the potential to ...

  2. Genetic Mutations and Environmental Exposure in Young Patients With Retinoblastoma and in Their Parents and Young Healthy Unrelated Volunteers - Mayo Clinic

    Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and ...

  3. Donor-Specific Cell Free DNA Monitoring of Thoracic Allografts - Mayo Clinic

    The purpose of this study is to determine if DNA originating from the transplanted heart or lung can be detected in the blood and used to monitor for rejection.

  4. Muscle Metabolism Characteristics Related to Diabetes-Related Conditions - Mayo Clinic

    Hypothesis 2: Greater trafficking of plasma FFA into intramyocellular ceramides will impair distal insulin signaling and reduce muscle glucose uptake.

  5. Study to Implement Shared Decision-Making Intervention in Practice for Chest Pain - Mayo Clinic

    About this study. The purpose of this study is to incorporate the Chest Pain Choice decision aid in a stakeholder-guided evidence-based clinical practice ...

  6. Validation of Pediatric Inflammatory Bowel Disease Knowledge Questions (Emma) - Mayo Clinic

    The aim of this study is to test the validity of the current question database in a large cohort of children with Inflammatory Bowel Disease (IBD) in several ...

  7. Identifying responders to MUC1 vaccine - Mayo Clinic

    About this study. A preventative MUC1 vaccine being tested in a clinical trial MAY13-01-01 in individuals with a history of advanced adenomas and an ...

  8. A Study to Evaluate both the Efficacy and Safety Profile of CP-690,550 in Patients with Moderately to Severely Active Ulcerative Colitis - Mayo Clinic

    This study is designed to evaluate the efficacy and safety of tofacitinib (CP-690,550) in patients with moderate to severe ulcerative colitis who have failed or ...

  9. DOM Phenotyping Project - Mayo Clinic

    The purpose of this research study is to help us better understand a person's risk of getting a disease or condition and what affects disease progression. We ...

  10. A Study Comparing Conventional Bilevel Positive Airway Pressure with a Back Up Rate, to Average Volume Assured Pressure Support for Treating Sleep Disordered Breathing in Patients with Neuromuscular Disease - Mayo Clinic

    The purpose of this study is to identify patients preference of one mode of noninvasive ventilation (BPAP-ST) over another (IPAP) in patients being treated for ...