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1. M402 in Combination With Nab-Paclitaxel and Gemcitabine in Pancreatic Cancer - Mayo Clinic

   Necuparanib has been re-engineered from heparin to have much lower blood thinning activity while keeping the anti-tumor activity. The investigators are testing ...

2. Colorectal Cancer - eMERGE Genome Informed Risk Assessment - Mayo Clinic Research

   EPCAM. MLH1. MSH2. MSH6. STK11. PMS2. For participants with monogenic risk, the GIRA report recommends referral to a genetic counselor.

3. A Study of the Effectiveness and Safety of Vedolizumab Compared to Adalimumab for Participants with Ulcerative Colitis - Mayo Clinic

   The purpose of this study is to evaluate the effectiveness and safety of vedolizumab intravenous (IV) treatment compared to adalimumab subcutaneous (SC) ...

4. Department of Molecular Pharmacology and Experimental Therapeutics Research - Affiliations

   Research activities within the Department of Molecular Pharmacology and Experimental Therapeutics are affiliated with several other Mayo Clinic research areas:.

5. Pivotal Study of the FRED Stent System in the Treatment of Intracranial Aneurysms - Mayo Clinic

   About this study. The purpose of this study is to evaluate the safety and effectiveness of the MicroVention Flow Redirection Intraluminal Device (FRED) ...

6. Efficacy and Safety of Adalimumab in Pediatric Subjects With Moderate to Severe Ulcerative Colitis - Mayo Clinic

   Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and ...

7. A Study to Evaluate the Effectiveness and Safety of Risankizumab in Subjects with Moderately-to-Severely Active Ulcerative Colitis - Mayo Clinic

   The objectives of Sub-Study 1 are to evaluate the efficacy, safety, and pharmacokinetics of risankizumab as induction treatment in subjects with moderately to ...

8. A Study to Evaluate the Efficacy and Safety of Lenalidomide as Maintenance Therapy for Patients With B-Cell Chronic Lymphocytic Leukemia (CLL) Following Second Line Therapy - Mayo Clinic

   The purpose of this study is to determine if lenalidomide (Revlimid®) is safe and effective as a maintenance therapy at improving further the quality of the ...

9. Biomechanics and Motion Analysis Lab - Effect of TGF-beta Inducible Early Gene Deficiency on Flexor Tendon Healing

   Recent developments in genetic and molecular biology research provide opportunities to investigate the molecular events of tendon healing. TGF-beta regulates ...

10. A Trial of the Effectiveness, Safety, and Tolerability of a Single Oral Administration of CP101 for the Prevention of Recurrent Clostridioides difficile Infection (PRISM4) - Mayo Clinic

    After completing standard-of-care (SOC) CDI antibiotics for their most recent CDI recurrence, patients who meet all eligibility requirements will be randomized ...