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  1. Randomized Controlled Trial of Tranexamic Acid in Total Knee Arthroplasty: Intravenous vs. Topical - Mayo Clinic

    Tranexamic acid is a synthetic drug that has been shown to reduce blood drain output and the need for blood transfusions in both its topical and intravenous ...

  2. A Study to Evaluate if a Conversation Aid Will Help Patients and Clinicians in Discuss Diagnostic Testing - Mayo Clinic

    About this study. The purpose of this study is to determine whether a diagnostic reconciliation conversation aid can assist a shared decision making ...

  3. Patient Self-collection Device for EDTA Whole-blood Assessment of Tacrolimus Therapeutic Dosage Monitoring - Mayo Clinic

    About this study. The objectives of this study are to compare the measured tacrolimus concentrations in patient self-collected capillary EDTA whole-blood ...

  4. A Study to Evaluate the Accuracy of Cardiac Acoustic Biomarkers by the Wearable Cardioverter Defibrillator - Mayo Clinic

    To show accuracy, these data will be compared with CABs data simultaneously recorded by the AUDICOR® AM device, a FDA cleared, acoustic cardiography recorder.

  5. A Study to Optimize Stroke Thrombolysis - Mayo Clinic

    Patients may also receive endovascular thrombectomy (ET) per usual care. Time of onset is defined as the last time the patient was last known to be well.

  6. Regional Prophylactic Vancomycin With Restricted Tourniquet Time in Primary Total Knee Replacement - Mayo Clinic

    The purpose of this study is to determine whether or not giving a lower dose of antibiotics (Vancomycin) in the area where it is needed (the knee joint) is more ...

  7. CD-NP (Cenderitide) Therapy for the Preservation of Left Ventricular Function Post Anterior Myocardial Infarction - Pilot Study - Mayo Clinic

    About this study. The primary endpoint is to assess the safety and tolerability of CD-NP with the incidence of symptomatic hypotension being one of the key ...

  8. A Study of the Effect of MD1003 in Progressive Multiple Sclerosis (SPI2) - Mayo Clinic

    About this study. The purpose of this study is to demonstrate the superiority of MD1003 (300 mg/day) over placebo to clinically improve patients with ...

  9. Inpatient, Dose-Ranging Study of Staccato Alprazolam in Epilepsy With Predictable Seizure Pattern - Mayo Clinic

    These subjects have an established diagnosis of focal or generalized epilepsy with a documented history of predictable seizure episodes. This is an in-patient ...

  10. Stress Management and Resilience Training (SMART) Intervention for Family Caregivers of Individuals With Advanced Cancer - Mayo Clinic

    This study examines Stress Management and Resilience Training (SMART) for family caregivers (FCG) of patients receiving chemotherapy for advanced cancer to ...