Search Results 111-120 of 8354 for TNF

  1. A Phase 3 Randomized, Double-blind, Placebo-controlled, Parallel-group Efficacy and Safety Study of SHP647 as Induction Therapy in Subjects With Moderate to Severe Ulcerative Colitis (FIGARO UC 302) - Mayo Clinic

    ... TNF. Subjects receiving any treatment(s) for UC are eligible provided they have been, and are anticipated to be, on a stable dose for the designated period ...

  2. A Study to Evaluate the Safety and Effectiveness of Ustekinumab Induction and Maintenance Therapy in Participants with Moderately to Severely Active Ulcerative Colitis - Mayo Clinic

    OR has not had biologic therapy (TNF antagonists or vedolizumab); Has received biologic therapy but has not demonstrated a history of failure to respond to ...

  3. Overview - Translational Polycystic Kidney Disease (PKD) Center - Mayo Clinic Research

    His research laboratory focuses on epigenetics, TNF-alpha and inflammatory signaling, and senescence in PKD, among other mechanisms. Funding. The Mayo Clinic ...

  4. Researchers explore whether senescence-associated secretory phenotype (SASP) is a potential driver of age-related dysfunction - Mayo Clinic

    Growth differentiation factor 15 (GDF15) · Tumor necrosis factor receptor superfamily member 6 (TNFRSF6) · Osteopontin (OPN) · TNF receptor 1 (TNFR1) · Activin A ...

  5. Randomized Study of Topical Alicaforsen Enema in Antibiotic Refractory Pouchitis - Mayo Clinic

    Biological agents: Anti-tumour necrosis factor (anti - TNF) therapy and / or vedolizumab; are not permitted within 8 weeks of the Screening Visit. All other ...

  6. Multicenter Study Evaluating Certolizumab Pegol Compared to Placebo in Subjects With axSpA Without X-ray Evidence of AS - Mayo Clinic

    Exposure to more than 1 TNF-antagonist or primary failure to TNF antagonist therapy; History of or current chronic or recurrent infections; Subjects with ...

  7. Neoadjuvant Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF) in Cutaneous Stage L-lll Melanoma - Mayo Clinic

    Immunosuppressive mediations (steroids, tumor necrosis factor (TNF)-inhibitors, azathioprine, etc.) within the past 6 weeks; Active or chronic infection with ...

  8. A Study of the Effectiveness of Methotrexate as Initial Treatment and Maintenance of a Steroid Free Remission in Ulcerative Colitis - Mayo Clinic

    Primary failure or loss of response to an anti-TNF (infliximab, adalimumab, golimumab) in the past; Primary failure or loss of response to vedolizumab in the ...

  9. Stem Cell Fistula Plug in Perianal Crohn's Disease - Mayo Clinic

    Concurrent therapies with corticosteroids, 5-ASA drugs, thiopurines, MTX, antibiotics, and anti-TNF therapy are permitted. All patients should have ...

  10. David A. Wetter, M.D. - Mayo Clinic Faculty Profiles

    Paradoxical autoimmune side effects of tumor necrosis factor-alpha inhibitors, including psoriasis, lupus and vasculitis. Significance to patient care. Dr ...