Search Results 1151-1160 of 16276 for monoclonal antibody

  1. Further Cardiovascular Outcomes Research with PCSK9 Inhibition in Subjects With Elevated Risk - Mayo Clinic

    Evolocumab is a monoclonal antibody that inhibits proprotein convertase subtilisin-kexin type 9 (PCSK9) and lowers low-density lipoprotein (LDL) cholesterol ...

  2. Daratumumab for Chemotherapy-Refractory Minimal Residual Disease in T Cell ALL - Mayo Clinic

    Daratumumab is a human immunoglobulin G1κ monoclonal antibody that binds CD38, and has been demonstrated to be safe and effective in patients with ...

  3. Daratumumab Retreatment in Participants With Multiple Myeloma Who Have Been Previously Treated With Daratumumab Intravenous (Dara-IV) - Mayo Clinic

    Allergies, hypersensitivity, or intolerance to daratumumab, hyaluronidase, monoclonal antibodies (mAbs), human proteins, or their excipients, or known ...

  4. Heart Transplant Research Program - Transplant Research Center - Mayo Clinic Research

    Mayo Clinic investigators were leaders in showing that the presence of anti-HLA antibodies can lead to graft vasculopathy. Surrogate endpoints and biomarkers.

  5. Exploring Mechanisms of Action and Resistance of Therapeutic Agents in Patients with B-cell Malignancies - Mayo Clinic

    This study is being performed to understand the causes of drug resistance and to improve the treatment options for patients diagnosed with B-cell cancers. We ...

  6. Breast Cancer SPORE - Mayo Clinic Research

    Project 4: P95HER2, Antitumor Immunity and the Efficacy of HER2-Directed Antibody Drug Conjugates. We're studying p95HER2 for better treatment options in ...

  7. Z-Endoxifen Hydrochloride in Treating Patients with Metastatic or Locally Recurrent Estrogen Receptor-Positive Breast Cancer - Mayo Clinic

    Monoclonal antibodies ≤ 3 weeks; Radiation therapy ≤ 3 weeks; Anti-Her-2 directed therapy ≤ 3 weeks. Prior endoxifen therapy; Prior history of: Stroke ≤ 6 ...

  8. A Study of the Safety and Effectiveness of GS-5745 in Participants with Moderately to Severely Active Crohn's Disease - Mayo Clinic

    Treatment with any monoclonal antibody within 4 weeks of screening; History or evidence of colonic mucosal dysplasia; HIV, hepatitis B, hepatitis C, or ...

  9. Hepatitis b immune globulin (intramuscular route, intravenous route) - Mayo Clinic

    Sexual partners of persons with hepatitis B. Persons who may be exposed to the virus by means of blood, blood products, or human bites, such as health care ...

  10. Broad Evidence of Systemic Immune Activation in Long Term Survivors of Advanced Ovarian Cancer - Mayo Clinic

    ... antibody responses to folate receptor alpha and will have broad evidence of systemic immune activation. Participation eligibility. Participant eligibility ...