Transplant Medicine

Below are current clinical trials.

Filter this list of studies by location, status and more.

1. A Study Looking at the Impact of Gabriel House of Care (a Hospital Hospitality House, HHH) on the Quality of Life and Mood of Liver Transplant Patients

   Jacksonville, Fla.

   The aim of this study is to measure the differences in quality of life and mood of liver transplant recipients in the immediate month post- transplant staying at the Gabriel House of Care staying at a hotel, apartment or rental property. 

2. Obesity Treatment Outcomes in Liver Transplant Recipients

   Scottsdale/Phoenix, Ariz.

   The purpose of this study is to prospectively evaluate the safety and effectiveness of standard of care, individualized, comprehensive weight loss interventions in carefully selected patients with obesity undergoing liver transplant evaluation, including utilization of best lifestyle modifications and guidance to promote a healthy weight, possible medical therapy using FDA-approved weight loss medications and EBMTs with or without concomitant medical therapy.

3. A Pilot Study Examining Thiamine Deficiency in Patients Admitted to the Hospital for Liver Transplantation

   Jacksonville, Fla.

   The purpose of this study is to report the proportion of thiamine deficiency (as defined by the Mayo Clinic Laboratory reference range) in liver transplant patients.

4. A Study of Immune Cell Abnormalities Found in Individual Patients who have Type 1 Diabetes and are Waiting for Pancreas or Pancreas/Kidney Transplant Surgery

   Rochester, Minn.

   The purpose of this study is to measure and characterize specific immune cell abnormalities found in patients who have type 1 diabetes and may or may not be on the waiting list for either a pancreas alone or a pancreas and kidney transplant.

5. A Study of In Vitro Mapping of Cardiac Tissue Obtained from Patients with Refractory Arrhythmias who Underwent Heart Transplant or Replacement with Mechanical Heart

   Rochester, Minn.

   The purpose of this study is to obtain electro-anatomic maps of human myocardium in sinus rhythm and ventricular arrhythmias to identify activation patterns, identify and perform tissue ablation at targeted sites of interest that could play an important trigger for development of arrhythmias, and to perform histologic analysis of the myocardial tissue to identify triggers and/or targets for therapies to terminate ventricular arrhythmias.

6. A Study to Evaluate the Effect of Inspiratory Muscle Training on Physiological Function and Clinical Outcomes Following Lung Transplant

   Jacksonville, Fla.

   The purpose of this study is to to mechanistically investigate the effect of specific inspiratory muscle training on respiratory function, exercise capacity, health-related quality-of-life, and short-term clinical outcomes in patients after lung transplant.

7. APOL1 Long-term Kidney Transplantation Outcomes Network (APOLLO)

   Rochester, Minn.

   The purpose of this study is to attempt to improve outcomes after kidney transplantation and to improve the safety of living kidney donation based upon variation in the apolipoprotein L1 gene (APOL1). Genes control what is inherited from a family, such as eye color or blood type. Variation in APOL1 can cause kidney disease. African Americans, Afro-Caribbeans, Hispanic Blacks, and Africans are more likely to have the APOL1 gene variants that cause kidney disease. APOLLO will test DNA from kidney donors and recipients of kidney transplants for APOL1 to determine effects on kidney transplant-related outcomes.

8. Lost Wages Support for Living Organ Donors Demonstration Project

   Scottsdale/Phoenix, Ariz.

   The purpose of this study will be to evaluate the effect of the US Health Resources and Services Administration (HRSA) program to reimburse lost wages on the decision of individuals to initiate evaluation for living organ donation.

9. Vancomycin for Primary Sclerosing Cholangitis

   Rochester, Minn., Jacksonville, Fla., Scottsdale/Phoenix, Ariz.

   The purpose of this study is to to assess the effects of different Oral Vancomycin (OV) doses on the clinical and biochemical course in adult patients with Primary Sclerosing Cholangitis (PSC).

10. A Study to Compare Medical and Non-Medical Coping on Functional Outcomes and Caregiver Burden Among Liver Transplant Patients

    Jacksonville, Fla.

    The purpose of this study is to compare functional improvement and caregiver burden pre- and post-liver transplant (LT) in four patient and patient’s primary caregiver dyads, grouped, based on presence or absence of mood symptoms pre-LT.