Surgery

Below are current clinical trials.

70 studies in Surgery
(open studies only).

Filter this list of studies by location, status and more.

1. A Study of the Ability to Predict Lymphedema Development Following Axillary Surgery for Breast Cancer and Its Effects on Patient Survivorship

   Jacksonville, Fla.

   The purpose of this study is to better understand the anatomy of the lymphatic structure and the molecular process that leads to the over production of lymph fluid.  This proposal will begin intense lymphedema screening and identify baseline characteristics potentially predisposing someone to lymphedema, and identify molecular markers that might be altered to prevent lymphedema. 

2. A Study of Simulated Sylvian Fissure Dissection Under Subarachnoid Hemorrhage Conditions Using a Rodent Microvascular Anastomosis Model

   Rochester, Minn.

   The purpose of this study is to assess the differences in microvascular anastomosis outcomes between the experiment aneurysmal subarachnoid hemorrhage (aSAH)-like conditions and control animals.

3. Analysis of the Cardiac, Aorta and Carotid Artery Walls for Hemodynamic Monitoring in the Intensive Care Unit

   Jacksonville, Fla.

   The primary aim of this study is to determine if biomechanical properties of cardiac and large arterial walls measured by ultrasound-based novel imaging technology correlate with hemodynamic parameters measured by other tools in the ICU.

4. A Study to Collect Ovarian Tissue from Girls Undergoing Fertility-preserving Cryopreservation

   Rochester, Minn.

   The purpose of this study is to study the handling of ovarian tissue, cryopreservation technology, and oocyte maturation for female pediatric cancer patients and other female patients whose future fertility will be affected due to a disease or treatment.

5. Sugar Hyperabsorption Impact on Post-Bariatric Surgery Weight Loss Outcomes in African American Patients

   Jacksonville, Fla.

   The purpose of this study is to investigate glucose and fructose absorption in enteroids from obese African American subjects before and 1-year post-bariatric surgery compared to age and sex-matched enteroids from obese Caucasian and Hispanic subjects (controls). Also, to profile the expression of glucose and fructose transporters and gluconeogenic enzymes in intestinal tissue from obese African American subjects and compare it to obese Caucasian and Hispanic subjects pre- and post-bariatric surgery.

6. Clinical Outcomes of Patients Treated With Open Surgical Repair for Complex Aortic Aneurysms

   Rochester, Minn.

   This is a prospective, non-randomized, single center, data collection study of patients treated with open surgical repair (OR) for complex aortic aneurysms (CAAs).

7. A Study of Blood Clotting Response in Patients with a Traumatic Injury

   Rochester, Minn.

   The purpose of this study is to look at the blood’s clotting response in people who have suffered a traumatic injury and compare it with non-injured people.

8. A Study to Evaluate Preiser's Disease and Its Complications

   Rochester, Minn.

   The purpose of this study is to describe the outcome and complications in surgical management of Preiser',s disease in the past 30 years in the Mayo Clinic.

9. A Study to Evaluate Same Day Discharge Post-mastectomy with/without Alloplastic Breast Reconstruction

   Rochester, Minn.

   In the light of the pandemic, institutions have had to take greater precautions and instigate procedures to aim to improve safety and reduce risk for patients undergoing surgery. One intiative was designed to implement a same day discharge for patients undergoing mastectomy with or without alloplastic reconstruction. This study aims to evaluate the outcomes and patient satisfaction with same day mastectomy with or without alloplastic reconstruction following COVID-19 and compare satisfaction and outcomes (e.g complications) with patients pre-COVID 19. This is part of a quality improvement project. 

10. Defining the Immunologic Profile of Sentinel Lymph Nodes and Identifying the Mechanisms Responsible for Immunosuppression

    Rochester, Minn., Jacksonville, Fla.

    The purpose of this study is to look at the effects cancer and melanoma have on the immune cells found in lymph nodes.