Mayo Clinic Q&A podcast: COVID-19 and multisystem inflammatory syndrome in children Oct. 09, 2020 Overview Show transcript Overview Children who become ill with COVID-19 sometimes develop a rare but serious reaction called multisystem inflammatory syndrome in children (MIS-C). This reaction causes various organs to become inflamed, including the heart, lungs, intestinal tract and brain. More than 600 cases of MIS-C were reported in the U.S. as of Aug. 20, 2020, most in minority populations. On this Mayo Clinic Q&A podcast, Emily R. Levy, M.D., a pediatric critical care and infectious disease expert at Mayo Clinic in Rochester, Minnesota, gives an overview of MIS-C ? including its similarities with Kawasaki disease. This interview was recorded Aug. 31, 2020. Information in this podcast was accurate at the time of its posting. Due to the fluid nature of the COVID-19 pandemic, scientific understanding, guidelines and recommendations may have changed since the original publication date. Receive Mayo Clinic news in your inbox. Sign up VID-20503156 Medical Professionals Mayo Clinic Q&A podcast: COVID-19 and multisystem inflammatory syndrome in children