Clinical Trials Below are current clinical trials.94 studies in Cardiovascular Diseases and Cardiac Surgery (open studies only). Filter this list of studies by location, status and more. Genotype-Phenotype Correlation in Cardiovascular Disease Rochester, Minn. This research study is being done to help characterize cardiovascular disease and improve diagnostic tests. OBJECTIVES To understand the pathogenesis, molecular mechanisms, and disease progression of heritable cardiovascular disease To evaluate the incidence of occult heritable cardiovascular disease in various populations. To correlate imaging and pathological phenotype with genotype to the ends described above. A Study to Evaluate Potential Myocardial Injury Following Magnetic Resonance Imaging (MRI) Rochester, Minn. The purpose of this study is to prospectively determine if magnetic resonance imaging (MRI) in patients with cardiac implantable electronic devices (CIED) results in myocardial injury as assessed by changes in high sensitivity cardiac troponin T (hs-cTnT) assay. This will be done by comparing pre-and-post MRI hs-cTnT levels in these patients. Echocardiographic Measures of Pulmonary Vascular Distensibility and Effects on Lung Diffusing Capacity Rochester, Minn. The purpose of this study is to determine if the change in pulmonary vascular compliance with positional changes (upright, supine, and Trendelenburg position) is different in younger versus older individuals. Prevalence of Transthyretin Cardiac Amyloidosis in Clinically Significant Aortic Stenosis Rochester, Minn. The purpose of this study is to determine the prevalence of TTR-CA in a community-based cohort of moderate and severe aortic stenosis patients using 99mTc-PYP single-photon positive emission computed tomography with computed tomography (SPECT/CT). A Study to Evaluate Wellness Coaching for Caregivers of Thoracic Transplant Candidates Rochester, Minn. The purpose of this study is to examine the effects of a health coaching intervention on the stress and burden of caregivers of patients awaiting heart or lung transplant. Hypotheses: Caregivers will have traits and behaviors pre-transplant that will predict caregiver readiness, quality of life, and transplant recipient outcomes. Specifically, thoracic pre-transplant caregivers report stress, symptoms of anxiety or depression, and perceive high caregiver burden. These factors may be amenable to pre-transplant intervention to improve overall patient and caregiver outcomes. Aims, purpose, or objectives: We will conduct a pilot trial to test whether caregivers of heart and lung transplant candidates who receive wellness coaching will experience improvement in caregiver-related distress. We will also explore the relationship between caregiving and factors such as uncertainty, resilience, stress level, and affect. Peripheral Nerve Stimulation Therapy for Atrial Fibrillation Rochester, Minn. The purpose of this study is to determine and compare the safety and efficacy of transcutaneous afferent patterned stimulation (TAPS) and respiratory-gated auricular vagal afferent nerve stimulation (RAVANS) therapies for the reduction of paroxysmal atrial fibrillation (AF) burden. Angiographic and Psychosocial Evaluation of Peripartum vs. Non Peripartum Spontaneous Coronary Artery Dissection (SCAD Rochester, Minn. The purpose of this study is to determine differences in clinical and imaging presentation, in-hospital management and prognosis in peri-partum and non-peri-partum SCAD patients. Invasive and Noninvasive Assessments of Myocardial Elasticity Rochester, Minn. The purpose of this study is to assess the correlation between myocardial elasticity (ME) measurements obtained simultaneously during cardiac hemodynamic catheterization and intraprocedural echocardiography. A Study to Analyze Association of Frequent Premature Ventricular Complex with Stroke or Transient Ischemic Attack Rochester, Minn. The purpose of this study is to verify that high Premature Ventricular Complex (PVC) burden is associated with increased risk of stroke and/or Transient Ischemic Attack (TIA), to examine outcomes such as stroke/TIA, atrial fibrillation/flutter, and all-cause mortality associated with PVCs, and to evaluate whether PVCs are associated with development of appendage dysfunction. A Study of the Effect of Myectomy on the Sudden Cardiac Death Risk in Hypertrophic Cardiomyopathy Rochester, Minn. The primary purpose/objective of this study is to determine whether myectomy as a management option for severe hypertrophic cardiomyopathy (HCM) reduces the incidence of sudden cardiac death. Pagination Clinical studies PrevPrevious Page Go to page 11 Go to page 22 Go to page 33 Go to page 44 Go to page 55 NextNext Page Medical Professionals Cardiovascular Diseases & Cardiac Surgery Clinical Trials