Faculty

Charles H. Adler, M.D., Ph.D.

Publications

Tremblay C, Adler CH, Shill HA, Driver-Dunckley E, Mehta S, Choudhury P, Belden C, Shprecher DR, Lee-Iannotti JK, Atri A, Serrano GE, Beach TG. Predicting Post-Mortem alpha-Synuclein Pathology by the Combined Presence of Probable REM sleep behavior disorder and Hyposmia. Mov Disord Clin Pract. 2024 Nov 5 Epub 2024 Nov 05
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Choi A, Zhang N, Adler CH, Beach TG, Shill HA, Driver-Dunckley E, Mehta S, Belden C, Atri A, Sabbagh MN, Caviness JN. Resting-state EEG predicts cognitive decline in a neuropathologically diagnosed longitudinal community autopsied cohort. Parkinsonism Relat Disord. 2024 Nov; 128:107120 Epub 2024 Aug 31
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Miner AE, Groh JR, Tripodis Y, Adler CH, Balcer LJ, Bernick C, Zetterberg H, Blennow K, Peskind E, Ashton NJ, Gaudet CE, Martin B, Palmisano JN, Banks SJ, Barr WB, Wethe JV, Cantu RC, Dodick DW, Katz DI, Mez J, van Amerongen S, Cummings JL, Shenton ME, Reiman EM, Stern RA, Alosco ML, DIAGNOSE CTE Research Project. Examination of plasma biomarkers of amyloid, tau, neurodegeneration, and neuroinflammation in former elite American football players. Alzheimers Dement. 2024 Nov; 20 (11):7529-7546 Epub 2024 Oct 01
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Arciniega H, Baucom ZH, Tuz-Zahra F, Tripodis Y, John O, Carrington H, Kim N, Knyazhanskaya EE, Jung LB, Breedlove K, Wiegand TLT, Daneshvar DH, Rushmore RJ, Billah T, Pasternak O, Coleman MJ, Adler CH, Bernick C, Balcer LJ, Alosco ML, Koerte IK, Lin AP, Cummings JL, Reiman EM, Stern RA, Shenton ME, Bouix S. Brain morphometry in former American football players: findings from the DIAGNOSE CTE research project. Brain. 2024 Oct 3; 147 (10):3596-3610
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Arciniega H, Jung LB, Tuz-Zahra F, Tripodis Y, John O, Kim N, Carrington HW, Knyazhanskaya EE, Chamaria A, Breedlove K, Wiegand TL, Daneshvar D, Billah T, Pasternak O, Coleman MJ, Adler CH, Bernick C, Balcer LJ, Alosco ML, Lin AP, Koerte IK, Cummings JL, Reiman EM, Stern RA, Bouix S, Shenton ME. Cavum septum pellucidum in former American football players. Neurology-Clinical Practice. 2024 Oct; 14 (5):e200324
Arciniega H, Jung LB, Tuz-Zahra F, Tripodis Y, John O, Kim N, Carrington HW, Knyazhanskaya EE, Chamaria A, Breedlove K, Wiegand TLT, Daneshvar D, Billah T, Pasternak O, Coleman MJ, Adler CH, Bernick C, Balcer LJ, Alosco ML, Lin AP, Koerte IK, Cummings JL, Reiman EM, Stern RA, Bouix S, Shenton ME, DIAGNOSE CTE Research Project. Cavum Septum Pellucidum in Former American Football Players: Findings From the DIAGNOSE CTE Research Project. Neurol Clin Pract. 2024 Oct; 14 (5):e200324 Epub 2024 Aug 15
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Beach TG, Serrano GE, Zhang N, Driver-Dunckley ED, Sue LI, Shill HA, Mehta SH, Belden C, Tremblay C, Choudhury P, Atri A, Adler CH. Clinicopathological Heterogeneity of Lewy Body Diseases: The Profound Influence of Comorbid Alzheimer's Disease. medRxiv. 2024 Sep 4 Epub 2024 Sept 04
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Su Y, Liao H, Miller J, Dodick DW, Geda Y, Wethe JV, Falk B, Gurney J, Jung LB, Wiegand TLT, Tuz-Zahra F, Tripodis Y, Iliff JJ, Piantino J, Arciniega H, Kim CL, Pankatz L, Bouix S, Lin AP, Alosco ML, Daneshvar DH, Mez J, Sepehrband F, Rathi Y, Pasternak O, Coleman MJ, Adler CH, Bernick C, Balcer L, Cummings JL, Reiman EM, Stern RA, Shenton ME, Koerte IK, DIAGNOSE CTE Research Project. Repetitive Head Impacts and Perivascular Space Volume in Former American Football Players. JAMA Netw Open. 2024 Aug 1; 7 (8):e2428687 Epub 2024 Aug 01
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Pulukuri SV, Fagle TR, Trujillo-Rodriguez D, van Amerongen S, Bernick C, Geda YE, Wethe JV, Peskind ER, Katz DI, Alosco ML, Palmisano JN, Tripodis Y, Adler CH, Balcer LJ, Reiman EM, Shenton ME, Cummings JL, Stern RA, DIAGNOSE CTE Research Project. Characterizing Neurobehavioral Dysregulation Among Former American Football Players: Findings From the DIAGNOSE CTE Research Project. J Neuropsychiatry Clin Neurosci. 2024 Jul 22; appineuropsych20230133 Epub 2024 July 22
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Adler CH, Halverson M, Zhang N, Shill HA, Driver-Dunckley E, Mehta SH, Atri A, Caviness JN, Serrano GE, Shprecher DR, Belden CM, Sabbagh MN, Long K, Beach TG. Conjugal Synucleinopathies: A Clinicopathologic Study. Mov Disord. 2024 Jul; 39 (7):1212-1217 Epub 2024 Apr 10
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Jackson LM, Woodruff BK, Tremblay C, Shill HA, Beach TG, Serrano GE, Adler CH. Parkinson's Disease Associated with G2019S LRRK2 Mutations without Lewy Body Pathology. Mov Disord Clin Pract. 2024 Jul; 11 (7):874-878 Epub 2024 May 16
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Tremblay C, Aslam S, Walker JE, Lorenzini I, Intorcia AJ, Arce RA, Choudhury P, Adler CH, Shill HA, Driver-Dunckley E, Mehta S, Piras IS, Belden CM, Atri A, Beach TG, Serrano GE. RNA sequencing of olfactory bulb in Parkinson's disease reveals gene alterations associated with olfactory dysfunction. Neurobiol Dis. 2024 Jun 15; 196:106514 Epub 2024 Apr 24
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Mastenbroek SE, Vogel JW, Collij LE, Serrano GE, Tremblay C, Young AL, Arce RA, Shill HA, Driver-Dunckley ED, Mehta SH, Belden CM, Atri A, Choudhury P, Barkhof F, Adler CH, Ossenkoppele R, Beach TG, Hansson O. Disease progression modelling reveals heterogeneity in trajectories of Lewy-type alpha-synuclein pathology. Nat Commun. 2024 Jun 15; 15 (1):5133 Epub 2024 June 15
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Heyes R, Adler CH, Yee C, Lott DG, Karle WE. Analgesia in Transcutaneous Laryngeal Botulinum Toxin Injections: A Randomized Crossover Trial. Laryngoscope. 2024 May; 134 (5):2277-2281 Epub 2023 Dec 29
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Gibbons CH, Levine T, Adler C, Bellaire B, Wang N, Stohl J, Agarwal P, Aldridge GM, Barboi A, Evidente VGH, Galasko D, Geschwind MD, Gonzalez-Duarte A, Gil R, Gudesblatt M, Isaacson SH, Kaufmann H, Khemani P, Kumar R, Lamotte G, Liu AJ, McFarland NR, Miglis M, Reynolds A, Sahagian GA, Saint-Hillaire MH, Schwartzbard JB, Singer W, Soileau MJ, Vernino S, Yerstein O, Freeman R. Skin Biopsy Detection of Phosphorylated alpha-Synuclein in Patients With Synucleinopathies. JAMA. 2024 Apr 16; 331 (15):1298-1306
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Banks SJ, Yhang E, Tripodis Y, Su Y, Protas H, Adler CH, Balcer LJ, Bernick C, Mez JB, Palmisano J, Barr WB, Wethe JV, Dodick DW, Mcclean MD, Martin B, Hartlage K, Turner A, Turner RW, Malhotra A, Colman M, Pasternak O, Lin AP, Koerte IK, Bouix S, Cummings JL, Shenton ME, Reiman EM, Stern RA, Alosco ML. Clinical Outcomes and Tau Pathology in Retired Football Players: Associations With Diagnosed and Witnessed Sleep Apnea. Neurol Clin Pract. 2024 Apr; 14 (2):e200263 Epub 2024 Feb 26
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Adler CH, Serrano GE, Shill HA, Driver-Dunckley E, Mehta SH, Zhang N, Glass M, Sue LI, Intorcia A, Beach TG. Symmetry of synuclein density in autopsied Parkinson's disease submandibular glands. Neurosci Lett. 2024 Mar 10; 825:137702 Epub 2024 Feb 21
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Alosco ML, Adler CH, Dodick DW, Tripodis Y, Balcer LJ, Bernick C, Banks SJ, Barr WB, Wethe JV, Palmisano JN, Martin B, Hartlage K, Cantu RC, Geda YE, Katz DI, Mez J, Cummings JL, Shenton ME, Reiman EM, Stern RA, DIAGNOSE CTE Research Project. Examination of parkinsonism in former elite American football players. Parkinsonism Relat Disord. 2024 Mar; 120:105903 Epub 2023 Nov 14
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Su Y, Protas H, Luo J, Chen K, Alosco ML, Adler CH, Balcer LJ, Bernick C, Au R, Banks SJ, Barr WB, Coleman MJ, Dodick DW, Katz DI, Marek KL, McClean MD, McKee AC, Mez J, Daneshvar DH, Palmisano JN, Peskind ER, Turner RW 2nd, Wethe JV, Rabinovici G, Johnson K, Tripodis Y, Cummings JL, Shenton ME, Stern RA, Reiman EM, DIAGNOSE CTE Research Project Investigators. Flortaucipir tau PET findings from former professional and college American football players in the DIAGNOSE CTE research project. Alzheimers Dement. 2024 Mar; 20 (3):1827-1838 Epub 2023 Dec 22
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Badihian N, Savica R, Adler CH, Wszolek ZK, Jackson LM, Benarroch EE, Sandroni P, Low PA, Singer W, Coon EA. Clinical Characteristics and Outcomes in Young-Onset Multiple System Atrophy. Mov Disord Clin Pract. 2024 Mar; 11 (3):220-226 Epub 2023 Nov 23
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Heyes R, Adler C, Zhang N, Abdel-Aty Y, Lott DG, Bansberg SF. Tremor Makes a Difference: A Comparative Study of the Demographics and Treatment Outcomes in Patients With Adductor Spasmodic Dysphonia With or Without Vocal Tremor. J Voice. 2024 Feb 19 [Epub ahead of print]
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Su Y, Liao H, Miller J, Dodick DW, Falk B, Gurney J, van Amerongen S, Pulukuri SV, Tuz-Zahra F, Tripodis Y, Cherry JD, Bernick C, Geda YE, Wethe JV, Katz DI, Alosco ML, Adler CH, Balcer LJ, Ashton NJ, Blennow K, Zetterberg H, Daneshvar DH, Colasurdo EA, Iliff JJ, Li G, Peskind ER, Shenton ME, Reiman EM, Cummings JL, Stern RA, DIAGNOSE CTE Research Project Investigators. Inflammatory biomarkers for neurobehavioral dysregulation in former American football players: findings from the DIAGNOSE CTE Research Project. J Neuroinflammation. 2024 Feb 9; 21 (1):46 Epub 2024 Feb 09
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Cardoso F, Goetz CG, Mestre TA, Sampaio C, Adler CH, Berg D, Bloem BR, Burn DJ, Fitts MS, Gasser T, Klein C, de Tijssen MAJ, Lang AE, Lim SY, Litvan I, Meissner WG, Mollenhauer B, Okubadejo N, Okun MS, Postuma RB, Svenningsson P, Tan LCS, Tsunemi T, Wahlstrom-Helgren S, Gershanik OS, Fung VSC, Trenkwalder C. A Statement of the MDS on Biological Definition, Staging, and Classification of Parkinson's Disease. Mov Disord. 2024 Feb; 39 (2):259-266 Epub 2023 Dec 13
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Hoglinger GU, Adler CH, Berg D, Klein C, Outeiro TF, Poewe W, Postuma R, Stoessl AJ, Lang AE. A biological classification of Parkinson's disease: the SynNeurGe research diagnostic criteria. Lancet Neurol. 2024 Feb; 23 (2):191-204
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Ly MT, Tuz-Zahra F, Tripodis Y, Adler CH, Balcer LJ, Bernick C, Zetterberg H, Blennow K, Peskind ER, Au R, Banks SJ, Barr WB, Wethe JV, Bondi MW, Delano-Wood LM, Cantu RC, Coleman MJ, Dodick DW, McClean MD, Mez JB, Palmisano J, Martin B, Hartlage K, Lin AP, Koerte IK, Cummings JL, Reiman EM, Shenton ME, Stern RA, Bouix S, Alosco ML, for DIAGNOSE CTE Research Project. Association of Vascular Risk Factors and CSF and Imaging Biomarkers With White Matter Hyperintensities in Former American Football Players. Neurology. 2024 Jan 23; 102 (2):e208030 Epub 2023 Dec 20
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Petersen RC, Weintraub S, Sabbagh M, Karlawish J, Adler CH, Dilworth-Anderson P, Frank L, Huling Hummel C, Taylor A, Dementia Nomenclature Initiative. A New Framework for Dementia Nomenclature. JAMA Neurol. 2023 Dec 1; 80 (12):1364-1370
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Su Y, Liao H, Miller J, Dodick DW, Geda Y, Wethe JV, Falk B, Gurney J, Stern RA, Trujillo-Rodriguez D, Tripodis Y, Pulukuri SV, Alosco ML, Adler CH, Balcer LJ, Bernick C, Baucom Z, Marek KL, McClean MD, Johnson KA, McKee AC, Stein TD, Mez J, Palmisano JN, Cummings JL, Shenton ME, Reiman EM, DIAGNOSE CTE Research Project Investigators. Amyloid PET across the cognitive spectrum in former professional and college American football players: findings from the DIAGNOSE CTE Research Project. Alzheimers Res Ther. 2023 Oct 5; 15 (1):166 Epub 2023 Oct 05
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Choudhury P, Zhang N, Adler CH, Chen K, Belden C, Driver-Dunckley E, Mehta SH, Shprecher DR, Serrano GE, Shill HA, Beach TG, Atri A. Longitudinal motor decline in dementia with Lewy bodies, Parkinson disease dementia, and Alzheimer's dementia in a community autopsy cohort. Alzheimers Dement. 2023 Oct; 19 (10):4377-4387 Epub 2023 July 08
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Bruce HJ, Tripodis Y, McClean M, Korell M, Tanner CM, Contreras B, Gottesman J, Kirsch L, Karim Y, Martin B, Palmisano J, Abdolmohammadi B, Shih LC, Stein TD, Stern RA, Adler CH, Mez J, Nowinski C, McKee AC, Alosco ML. American Football Play and Parkinson Disease Among Men. JAMA Netw Open. 2023 Aug 1; 6 (8):e2328644 Epub 2023 Aug 01
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Hamsafar Y, Chen Q, Borowsky AD, Beach TG, Serrano GE, Sue LI, Adler CH, Walker DG, Dugger BN. Biochemical analyses of tau and other neuronal markers in the submandibular gland and frontal cortex across stages of Alzheimer disease. Neurosci Lett. 2023 Jul 27; 810:137330 Epub 2023 June 16
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Heyes R, Adler CH, Zhang N, Lott DG, Bansberg SF. Significance of age and sex in botulinum neurotoxin dosing for adductor spasmodic dysphonia. World J Otorhinolaryngol Head Neck Surg. 2023 Jun; 9 (2):168-173 Epub 2023 Jan 29
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Beach TG, Sue LI, Scott S, Intorcia AJ, Walker JE, Arce RA, Glass MJ, Borja CI, Cline MP, Hemmingsen SJ, Qiji S, Stewart A, Martinez KN, Krupp A, McHattie R, Mariner M, Lorenzini I, Kuramoto A, Long KE, Tremblay C, Caselli RJ, Woodruff BK, Rapscak SZ, Belden CM, Goldfarb D, Choudhury P, Driver-Dunckley ED, Mehta SH, Sabbagh MN, Shill HA, Atri A, Adler CH, Serrano GE. Cerebral white matter rarefaction has both neurodegenerative and vascular causes and may primarily be a distal axonopathy. J Neuropathol Exp Neurol. 2023 May 25; 82 (6):457-466
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Chahine LM, Beach TG, Adler CH, Hepker M, Kanthasamy A, Appel S, Pritzkow S, Pinho M, Mosovsky S, Serrano GE, Coffey C, Brumm MC, Oliveira LMA, Eberling J, Mollenhauer B, Systemic Synuclein Sampling Study. Central and peripheral alpha-synuclein in Parkinson disease detected by seed amplification assay. Ann Clin Transl Neurol. 2023 May; 10 (5):696-705 Epub 2023 Mar 27
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Shill HA, Adler CH, Tremblay C, Beach TG. Lack of significant Lewy pathology in 237 essential tremor brains. J Neuropathol Exp Neurol 2023 Apr 20; 82 (5):452-453
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Driver-Dunckley ED, Zhang N, Serrano GE, Dunckley NA, Sue LI, Shill HA, Mehta SH, Belden C, Tremblay C, Atri A, Adler CH, Beach TG. Low clinical sensitivity and unexpectedly high incidence for neuropathologically diagnosed progressive supranuclear palsy. J Neuropathol Exp Neurol. 2023 Apr 20; 82 (5):438-451
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Alosco ML, Tripodis Y, Baucom ZH, Adler CH, Balcer LJ, Bernick C, Mariani ML, Au R, Banks SJ, Barr WB, Wethe JV, Cantu RC, Coleman MJ, Dodick DW, McClean MD, McKee AC, Mez J, Palmisano JN, Martin B, Hartlage K, Lin AP, Koerte IK, Cummings JL, Reiman EM, Stern RA, Shenton ME, Bouix S, DIAGNOSE CTE Research Project. White matter hyperintensities in former American football players. Alzheimers Dement. 2023 Apr; 19 (4):1260-1273 Epub 2022 Aug 22
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Alosco ML, Barr WB, Banks SJ, Wethe JV, Miller JB, Pulukuri SV, Culhane J, Tripodis Y, Adler CH, Balcer LJ, Bernick C, Mariani ML, Cantu RC, Dodick DW, McClean MD, Au R, Mez J, Turner RW 2nd, Palmisano JN, Martin B, Hartlage K, Cummings JL, Reiman EM, Shenton ME, Stern RA, DIAGNOSE CTE Research Project. Neuropsychological test performance of former American football players. Alzheimers Res Ther. 2023 Jan 3; 15 (1):1 Epub 2023 Jan 03
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Tremblay C, Serrano GE, Dunckley N, Zhang N, Fiock KL, Adler CH, Driver-Dunckley E, Mehta SH, Shill HA, Beach TG. Postmortem Cerebellar Volume Is Not Reduced in Essential Tremor: A Comparison with Multiple System Atrophy and Controls. J Parkinsons Dis. 2023; 13 (3):333-340
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Alosco ML, Su Y, Stein TD, Protas H, Cherry JD, Adler CH, Balcer LJ, Bernick C, Pulukuri SV, Abdolmohammadi B, Coleman MJ, Palmisano JN, Tripodis Y, Mez J, Rabinovici GD, Marek KL, Beach TG, Johnson KA, Huber BR, Koerte I, Lin AP, Bouix S, Cummings JL, Shenton ME, Reiman EM, McKee AC, Stern RA, DIAGNOSE C. T. E. Research Project. Associations between near end-of-life flortaucipir PET and postmortem CTE-related tau neuropathology in six former American football players. Eur J Nucl Med Mol Imaging 2023 Jan; 50 (2):435-452 Epub 2022 Sept 24
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Hasan S, Adler CH, Zhang N, Serrano GE, Sue LI, Shill HA, Mehta SH, Beach TG, Driver-Dunckley ED. Olfactory Dysfunction in Incidental Lewy Body Disease and Parkinson's Disease: An Update. Innov Clin Neurosci. 2022 Oct-Dec; 19 (10-12):19-23
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Aslam S, Zhang N, Adler CH, Beach TG, Driver-Dunckley E, Mehta SH, Shill H. Clinicopathologic Correlations of Jaw Tremor in a Longitudinal Aging Study. Neurol Clin Pract. 2022 Oct; 12 (5):e85-e92
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Serrano GE, Walker JE, Tremblay C, Piras IS, Huentelman MJ, Belden CM, Goldfarb D, Shprecher D, Atri A, Adler CH, Shill HA, Driver-Dunckley E, Mehta SH, Caselli R, Woodruff BK, Haarer CF, Ruhlen T, Torres M, Nguyen S, Schmitt D, Rapscak SZ, Bime C, Peters JL, Alevritis E, Arce RA, Glass MJ, Vargas D, Sue LI, Intorcia AJ, Nelson CM, Oliver J, Russell A, Suszczewicz KE, Borja CI, Cline MP, Hemmingsen SJ, Qiji S, Hobgood HM, Mizgerd JP, Sahoo MK, Zhang H, Solis D, Montine TJ, Berry GJ, Reiman EM, Roltgen K, Boyd SD, Pinsky BA, Zehnder JL, Talbot P, Desforges M, DeTure M, Dickson DW, Beach TG. SARS-CoV-2 Brain Regional Detection, Histopathology, Gene Expression, and Immunomodulatory Changes in Decedents with COVID-19. J Neuropathol Exp Neurol. 2022 Aug 16; 81 (9):666-695
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Tremblay C, Serrano GE, Intorcia AJ, Mariner MR, Sue LI, Arce RA, Atri A, Adler CH, Belden CM, Shill HA, Driver-Dunckley E, Mehta SH, Beach TG. Olfactory Bulb Amyloid-beta Correlates With Brain Thal Amyloid Phase and Severity of Cognitive Impairment. J Neuropathol Exp Neurol. 2022 Jul 19; 81 (8):643-649
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Hall S, Orru CD, Serrano GE, Galasko D, Hughson AG, Groveman BR, Adler CH, Beach TG, Caughey B, Hansson O. Performance of alphaSynuclein RT-QuIC in relation to neuropathological staging of Lewy body disease. Acta Neuropathol Commun. 2022 Jun 22; 10 (1):90 Epub 2022 June 22
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Boel JA, de Bie RMA, Schmand BA, Dalrymple-Alford JC, Marras C, Adler CH, Goldman JG, Troster AI, Burn DJ, Litvan I, Geurtsen GJ, MDS Study Group Mild Cognitive Impairment in Parkinson's Disease. Level I PD-MCI Using Global Cognitive Tests and the Risk for Parkinson's Disease Dementia. Mov Disord Clin Pract. 2022 May; 9 (4):479-483 Epub 2022 Apr 29
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Gibbons CH, Freeman R, Bellaire B, Adler CH, Moore D, Levine T. Synuclein-One study: skin biopsy detection of phosphorylated alpha-synuclein for diagnosis of synucleinopathies. Biomark Med. 2022 May; 16 (7):499-509 Epub 2022 Mar 11
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Signaevsky M, Marami B, Prastawa M, Tabish N, Iida MA, Zhang XF, Sawyer M, Duran I, Koenigsberg DG, Bryce CH, Chahine LM, Mollenhauer B, Mosovsky S, Riley L, Dave KD, Eberling J, Coffey CS, Adler CH, Serrano GE, White CL 3rd, Koll J, Fernandez G, Zeineh J, Cordon-Cardo C, Beach TG, Crary JF. Antemortem detection of Parkinson's disease pathology in peripheral biopsies using artificial intelligence. Acta Neuropathol Commun. 2022 Feb 14; 10 (1):21
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Wang M, Sajobi T, Morgante F, Adler C, Agarwal P, Baumer T, Berardelli A, Berman BD, Blumin J, Borsche M, Brashear A, Deik A, Duque K, Espay AJ, Ferrazzano G, Feuerstein J, Fox S, Frank S, Hallett M, Jankovic J, LeDoux MS, Leegwater-Kim J, Mahajan A, Malaty IA, Ondo W, Pantelyat A, Pirio-Richardson S, Roze E, Saunders-Pullman R, Suchowersky O, Truong D, Vidailhet M, Shukla AW, Perlmutter JS, Jinnah HA, Martino D. Predictive modeling of spread in adult-onset isolated dystonia: Key properties and effect of tremor inclusion. Eur J Neurol. 2021 Dec; 28 (12):3999-4009 Epub 2021 Aug 04
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Lea R, Benge JF, Adler CH, Beach TG, Belden CM, Zhang N, Shill HA, Driver-Dunckley E, Mehta SH, Atri A. An initial exploration of the convergent and ecological validity of the UDS 3.0 neuropsychological battery in Parkinson's Disease. J Clin Exp Neuropsychol. 2021 Nov; 43 (9):918-925 Epub 2022 Feb 09
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Dutta S, Hornung S, Kruayatidee A, Maina KN, Del Rosario I, Paul KC, Wong DY, Duarte Folle A, Markovic D, Palma JA, Serrano GE, Adler CH, Perlman SL, Poon WW, Kang UJ, Alcalay RN, Sklerov M, Gylys KH, Kaufmann H, Fogel BL, Bronstein JM, Ritz B, Bitan G. alpha-Synuclein in blood exosomes immunoprecipitated using neuronal and oligodendroglial markers distinguishes Parkinson's disease from multiple system atrophy. Acta Neuropathol. 2021 Sep; 142 (3):495-511 Epub 2021 May 15
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Dutta S, Hornung S, Kruayatidee A, Maina KN, Del Rosario I, Paul KC, Wong DY, Duarte Folle A, Markovic D, Palma JA, Serrano GE, Adler CH, Perlman SL, Poon WW, Kang UJ, Alcalay RN, Sklerov M, Gylys KH, Kaufmann H, Fogel BL, Bronstein JM, Ritz B, Bitan G. Correction to: alpha-Synuclein in blood exosomes immunoprecipitated using neuronal and oligodendroglial markers distinguishes Parkinson's disease from multiple system atrophy. Acta Neuropathol. 2021 Sep; 142 (3):513
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Alosco ML, Mariani ML, Adler CH, Balcer LJ, Bernick C, Au R, Banks SJ, Barr WB, Bouix S, Cantu RC, Coleman MJ, Dodick DW, Farrer LA, Geda YE, Katz DI, Koerte IK, Kowall NW, Lin AP, Marcus DS, Marek KL, McClean MD, McKee AC, Mez J, Palmisano JN, Peskind ER, Tripodis Y, Turner RW 2nd, Wethe JV, Cummings JL, Reiman EM, Shenton ME, Stern RA, DIAGNOSE CTE Research Project Investigators. Developing methods to detect and diagnose chronic traumatic encephalopathy during life: rationale, design, and methodology for the DIAGNOSE CTE Research Project. Alzheimers Res Ther. 2021 Aug 12; 13 (1):136
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Wadon ME, Bailey GA, Yilmaz Z, Hubbard E, AlSaeed M, Robinson A, McLauchlan D, Barbano RL, Marsh L, Factor SA, Fox SH, Adler CH, Rodriguez RL, Comella CL, Reich SG, Severt WL, Goetz CG, Perlmutter JS, Jinnah HA, Harding KE, Sandor C, Peall KJ. Non-motor phenotypic subgroups in adult-onset idiopathic, isolated, focal cervical dystonia. Brain Behav. 2021 Aug; 11 (8):e2292 Epub 2021 July 21
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Miglis MG, Adler CH, Antelmi E, Arnaldi D, Baldelli L, Boeve BF, Cesari M, Dall'Antonia I, Diederich NJ, Doppler K, Dusek P, Ferri R, Gagnon JF, Gan-Or Z, Hermann W, Hogl B, Hu MT, Iranzo A, Janzen A, Kuzkina A, Lee JY, Leenders KL, Lewis SJG, Liguori C, Liu J, Lo C, Ehgoetz Martens KA, Nepozitek J, Plazzi G, Provini F, Puligheddu M, Rolinski M, Rusz J, Stefani A, Summers RLS, Yoo D, Zitser J, Oertel WH. Biomarkers of conversion to alpha-synucleinopathy in isolated rapid-eye-movement sleep behaviour disorder. Lancet Neurol. 2021 Aug; 20 (8):671-684
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Adler CH, Beach TG, Zhang N, Shill HA, Driver-Dunckley E, Mehta SH, Atri A, Caviness JN, Serrano G, Shprecher DR, Sue LI, Belden CM. Clinical Diagnostic Accuracy of Early/Advanced Parkinson Disease: An Updated Clinicopathologic Study. Neurol Clin Pract. 2021 Aug; 11 (4):e414-e421
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Shill HA, Zhang N, Driver-Dunckley E, Mehta S, Adler CH, Beach TG. Olfaction in Neuropathologically Defined Progressive Supranuclear Palsy. Mov Disord. 2021 Jul; 36 (7):1700-1704 Epub 2021 Mar 23
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Walters AS, Paueksakon P, Adler CH, Moussouttas M, Weinstock LB, Spruyt K, Bagai K. Restless Legs Syndrome Shows Increased Silent Postmortem Cerebral Microvascular Disease With Gliosis. J Am Heart Assoc. 2021 Jun; 10 (11):e019627 Epub 2021 May 15
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Katz DI, Bernick C, Dodick DW, Mez J, Mariani ML, Adler CH, Alosco ML, Balcer LJ, Banks SJ, Barr WB, Brody DL, Cantu RC, Dams-O'Connor K, Geda YE, Jordan BD, McAllister TW, Peskind ER, Petersen RC, Wethe JV, Zafonte RD, Foley EM, Babcock DJ, Koroshetz WJ, Tripodis Y, McKee AC, Shenton ME, Cummings JL, Reiman EM, Stern RA. National Institute of Neurological Disorders and Stroke Consensus Diagnostic Criteria for Traumatic Encephalopathy Syndrome. Neurology. 2021 May 4; 96 (18):848-863 Epub 2021 Mar 15
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Serrano GE, Walker JE, Arce R, Glass MJ, Vargas D, Sue LI, Intorcia AJ, Nelson CM, Oliver J, Papa J, Russell A, Suszczewicz KE, Borja CI, Belden C, Goldfarb D, Shprecher D, Atri A, Adler CH, Shill HA, Driver-Dunckley E, Mehta SH, Readhead B, Huentelman MJ, Peters JL, Alevritis E, Bimi C, Mizgerd JP, Reiman EM, Montine TJ, Desforges M, Zehnder JL, Sahoo MK, Zhang H, Solis D, Pinsky BA, Deture M, Dickson DW, Beach TG. Mapping of SARS-CoV-2 Brain Invasion and Histopathology in COVID-19 Disease. medRxiv 2021 Feb 18
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Shaikh AG, Beylergil SB, Scorr L, Kilic-Berkmen G, Freeman A, Klein C, Junker J, Loens S, Bruggemann N, Munchau A, Baumer T, Vidailhet M, Roze E, Bonnet C, Jankovic J, Jimenez-Shahed J, Patel N, Marsh L, Comella C, Barbano RL, Berman BD, Malaty I, Wagle Shukla A, Reich SG, Ledoux MS, Berardelli A, Ferrazzano G, Stover N, Ondo W, Pirio Richardson S, Saunders-Pullman R, Mari Z, Agarwal P, Adler C, Chouinard S, Fox SH, Brashear A, Truong D, Suchowersky O, Frank S, Factor S, Perlmutter J, Jinnah HA. Dystonia and Tremor: A Cross-Sectional Study of the Dystonia Coalition Cohort. Neurology. 2021 Jan 26; 96 (4):e563-e574 Epub 2020 Oct 12
View PubMed
Beach TG, Russell A, Sue LI, Intorcia AJ, Glass MJ, Walker JE, Arce R, Nelson CM, Hidalgo T, Chiarolanza G, Mariner M, Scroggins A, Pullen J, Souders L, Sivananthan K, Carter N, Saxon-LaBelle M, Hoffman B, Garcia A, Callan M, Fornwalt BE, Carew J, Filon J, Cutler B, Papa J, Curry JR, Oliver J, Shprecher D, Atri A, Belden C, Shill HA, Driver-Dunckley E, Mehta SH, Adler CH, Haarer CF, Ruhlen T, Torres M, Nguyen S, Schmitt D, Fietz M, Lue LF, Walker DG, Mizgerd JP, Serrano GE. Increased Risk of Autopsy-Proven Pneumonia with Sex, Season and Neurodegenerative Disease. medRxiv 2021 Jan 8 Epub 2021 Jan 08
View PubMed
Tiklova K, Gillberg L, Volakakis N, Lunden-Miguel H, Dahl L, Serrano GE, Adler CH, Beach TG, Perlmann T. Disease Duration Influences Gene Expression in Neuromelanin-Positive Cells From Parkinson's Disease Patients. Front Mol Neurosci. 2021; 14:763777 Epub 2021 Nov 11
View PubMed
Beach TG, Adler CH, Sue LI, Shill HA, Driver-Dunckley E, Mehta SH, Intorcia AJ, Glass MJ, Walker JE, Arce R, Nelson CM, Serrano GE. Vagus Nerve and Stomach Synucleinopathy in Parkinson's Disease, Incidental Lewy Body Disease, and Normal Elderly Subjects: Evidence Against the "Body-First" Hypothesis. J Parkinsons Dis. 2021; 11 (4):1833-1843
View PubMed
Gupta HV, Beach TG, Mehta SH, Shill HA, Driver-Dunckley E, Sabbagh MN, Belden CM, Liebsack C, Dugger BN, Serrano GE, Sue LI, Siderowf A, Pontecorvo MJ, Mintun MA, Joshi AD, Adler CH. Clinicopathological Correlation: Dopamine and Amyloid PET Imaging with Neuropathology in Three Subjects Clinically Diagnosed with Alzheimer's Disease or Dementia with Lewy Bodies. J Alzheimers Dis. 2021; 80 (4):1603-1612
View PubMed
Cisneros E, Stebbins GT, Chen Q, Vu JP, Benadof CN, Zhang Z, Barbano RL, Fox SH, Goetz CG, Jankovic J, Jinnah HA, Perlmutter JS, Adler CH, Factor SA, Reich SG, Rodriguez R, Severt LL, Stover NP, Berman BD, Comella CL, Peterson DA. It's tricky: Rating alleviating maneuvers in cervical dystonia. J Neurol Sci. 2020 Dec 15; 419:117205 Epub 2020 Nov 01
View PubMed
Adams JW, Alosco ML, Mez J, Alvarez VE, Huber BR, Tripodis Y, Adler CH, Kubilius C, Cormier KA, Mathais R, Nicks R, Kelley HJ, Saltiel N, Uretsky M, Nair E, Aytan N, Cherry JD, Nowinski CJ, Kowall NW, Goldstein LE, Dwyer B, Katz DI, Cantu RC, Stern RA, McKee AC, Stein TD. Association of probable REM sleep behavior disorder with pathology and years of contact sports play in chronic traumatic encephalopathy. Acta Neuropathol. 2020 Dec; 140 (6):851-862 Epub 2020 Sept 17
View PubMed
Manne S, Kondru N, Jin H, Serrano GE, Anantharam V, Kanthasamy A, Adler CH, Beach TG, Kanthasamy AG. Blinded RT-QuIC Analysis of alpha-Synuclein Biomarker in Skin Tissue From Parkinson's Disease Patients. Mov Disord. 2020 Dec; 35 (12):2230-2239 Epub 2020 Sept 22
View PubMed
Ortuno-Lizaran I, Sanchez-Saez X, Lax P, Serrano GE, Beach TG, Adler CH, Cuenca N. Dopaminergic Retinal Cell Loss and Visual Dysfunction in Parkinson Disease. Ann Neurol. 2020 Nov; 88 (5):893-906 Epub 2020 Sept 19
View PubMed
Adler CH, Zhang N, Crews D, McDaniel T, Tucker J, Marquardt C, Caviness JN. Dystonic Golfer's cramp: Pilot study of propranolol and looking at the hole. Parkinsonism Relat Disord. 2020 Nov; 80:108-112 Epub 2020 Sept 12
View PubMed
Chahine LM, Beach TG, Brumm MC, Adler CH, Coffey CS, Mosovsky S, Caspell-Garcia C, Serrano GE, Munoz DG, White CL 3rd, Crary JF, Jennings D, Taylor P, Foroud T, Arnedo V, Kopil CM, Riley L, Dave KD, Mollenhauer B, Systemic Synuclein Sampling Study. In vivo distribution of alpha-synuclein in multiple tissues and biofluids in Parkinson disease. Neurology. 2020 Sep 1; 95 (9):e1267-e1284 Epub 2020 Aug 03
View PubMed
Shprecher DR, Adler CH, Zhang N, Shill HA, Belden CM, Driver-Dunckley E, Mehta SH, Davis KJ, Sue LI, Zamrini E, Beach TG. Do Parkinson disease subject and caregiver-reported Epworth sleepiness scale reponses correlate? Clin Neurol Neurosurg. 2020 May; 192:105728 Epub 2020 Feb 06
View PubMed
Knox MG, Adler CH, Shill HA, Driver-Dunckley E, Mehta SA, Belden C, Zamrini E, Serrano G, Sabbagh MN, Caviness JN, Sue LI, Davis KJ, Dugger BN, Beach TG. Neuropathological Findings in Parkinson's Disease With Mild Cognitive Impairment. Mov Disord. 2020 May; 35 (5):845-850 Epub 2020 Feb 08
View PubMed
Ornelas AS, Adler CH, Serrano GE, Curry JR, Shill HA, Kopyov O, Beach TG. Co-Existence of tau and alpha-synuclein pathology in fetal graft tissue at autopsy: A case report. Parkinsonism Relat Disord. 2020 Feb; 71:36-39 Epub 2020 Jan 11
View PubMed
Beach TG, Adler CH, Zhang N, Serrano GE, Sue LI, Driver-Dunckley E, Mehta SH, Zamrini EE, Sabbagh MN, Shill HA, Belden CM, Shprecher DR, Caselli RJ, Reiman EM, Davis KJ, Long KE, Nicholson LR, Intorcia AJ, Glass MJ, Walker JE, Callan MM, Oliver JC, Arce R, Gerkin RC. Severe hyposmia distinguishes neuropathologically confirmed dementia with Lewy bodies from Alzheimer's disease dementia. PLoS One. 2020; 15 (4):e0231720 Epub 2020 Apr 22
View PubMed
Serrano GE, Shprecher D, Callan M, Cutler B, Glass M, Zhang N, Walker J, Intorcia A, Adler CH, Shill HA, Driver-Dunckley E, Mehta SH, Belden CM, Zamrini E, Sue LI, Vargas D, Beach TG. Cardiac sympathetic denervation and synucleinopathy in Alzheimer's disease with brain Lewy body disease. Brain Commun. 2020; 2 (1):fcaa004 Epub 2020 Jan 28
View PubMed
Gupta HV, Zhang N, Driver-Dunckley E, Mehta SH, Beach TG, Adler CH. Contrast Acuity With Different Colors in Parkinson's Disease. Mov Disord Clin Pract. 2019 Nov; 6 (8):672-677 Epub 2019 Sept 06
View PubMed
Adler CH, Serrano GE, Zhang N, Hinni ML, Lott DG, Mehta SH, Sue LI, Intorcia A, Beach TG. Feasibility of repeat and bilateral submandibular gland needle biopsies in Parkinson's disease. Parkinsonism Relat Disord. 2019 Nov; 68:69-72 Epub 2019 Oct 07
View PubMed
Dashtipour K, Mari Z, Jankovic J, Adler CH, Schwartz M, Brin MF. Minimal clinically important change in patients with cervical dystonia: Results from the CD PROBE study. J Neurol Sci. 2019 Oct 15; 405:116413 Epub 2019 July 27
View PubMed
Adler CH, Beach TG, Zhang N, Shill HA, Driver-Dunckley E, Caviness JN, Mehta SH, Sabbagh MN, Serrano GE, Sue LI, Belden CM, Powell J, Jacobson SA, Zamrini E, Shprecher D, Davis KJ, Dugger BN, Hentz JG. Unified Staging System for Lewy Body Disorders: Clinicopathologic Correlations and Comparison to Braak Staging. J Neuropathol Exp Neurol. 2019 Oct 1; 78 (10):891-899
View PubMed
Driver-Dunckley ED, Zhang N, Shill HA, Mehta SH, Belden CM, Zamrini EY, Davis K, Beach TG, Adler CH. Correlation Between the Movement Disorder Society's Unified Parkinson's Disease Rating Scale and Nonmotor Scales in Patients with Parkinson's Disease. Innov Clin Neurosci. 2019 Sep 1; 16 (9-10):27-29
View PubMed
El-Nazer R, Adler CH, Beach TG, Belden CM, Artz J, Shill HA, Driver-Dunckley E, Mehta SH, Sabbagh MN, Serrano GE, Sue LI, Zamrini E, Benge JF. Regional neuropathology distribution and verbal fluency impairments in Parkinson's disease. Parkinsonism Relat Disord. 2019 Aug; 65:73-78 Epub 2019 May 10
View PubMed
Stern RA, Adler CH, Chen K, Navitsky M, Luo J, Dodick DW, Alosco ML, Tripodis Y, Goradia DD, Martin B, Mastroeni D, Fritts NG, Jarnagin J, Devous MD Sr, Mintun MA, Pontecorvo MJ, Shenton ME, Reiman EM. Tau Positron-Emission Tomography in Former National Football League Players. N Engl J Med. 2019 May 2; 380 (18):1716-1725 Epub 2019 Apr 10
View PubMed
Dugger BN, Hoffman BR, Scroggins A, Serrano GE, Adler CH, Shill HA, Belden CM, Sabbagh MN, Caviness JN, Driver Dunckley E, Beach TG. Tau immunoreactivity in peripheral tissues of human aging and select tauopathies. Neurosci Lett. 2019 Mar 23; 696:132-139 Epub 2018 Dec 21
View PubMed
Hoogland J, Boel JA, de Bie RMA, Schmand BA, Geskus RB, Dalrymple-Alford JC, Marras C, Adler CH, Weintraub D, Junque C, Pedersen KF, Mollenhauer B, Goldman JG, Troster AI, Burn DJ, Litvan I, Geurtsen GJ, MDS Study Group "Validation of Mild Cognitive Impairment in Parkinson Disease". Risk of Parkinson's disease dementia related to level I MDS PD-MCI. Mov Disord. 2019 Mar; 34 (3):430-435 Epub 2019 Jan 17
View PubMed
Malek-Ahmadi M, Beach TG, Zamrini E, Adler CH, Sabbagh MN, Shill HA, Jacobson SA, Belden CM, Caselli RJ, Woodruff BK, Rapscak SZ, Ahern GL, Shi J, Caviness JN, Driver-Dunckley E, Mehta SH, Shprecher DR, Spann BM, Tariot P, Davis KJ, Long KE, Nicholson LR, Intorcia A, Glass MJ, Walker JE, Callan M, Curry J, Cutler B, Oliver J, Arce R, Walker DG, Lue LF, Serrano GE, Sue LI, Chen K, Reiman EM. Faster cognitive decline in dementia due to Alzheimer disease with clinically undiagnosed Lewy body disease. PLoS One. 2019; 14 (6):e0217566 Epub 2019 June 25
View PubMed
Dong X, Liao Z, Gritsch D, Hadzhiev Y, Bai Y, Locascio JJ, Guennewig B, Liu G, Blauwendraat C, Wang T, Adler CH, Hedreen JC, Faull RLM, Frosch MP, Nelson PT, Rizzu P, Cooper AA, Heutink P, Beach TG, Mattick JS, Muller F, Scherzer CR. Publisher Correction: Enhancers active in dopamine neurons are a primary link between genetic variation and neuropsychiatric disease. Nat Neurosci. 2019 Jan; 22 (1):144-147
View PubMed
Savica R, Beach TG, Hentz JG, Sabbagh MN, Serrano GE, Sue LI, Dugger BN, Shill HA, Driver-Dunckley E, Caviness JN, Mehta SH, Jacobson SA, Belden CM, Davis KJ, Zamrini E, Shprecher DR, Adler CH. Lewy body pathology in Alzheimer's disease: A clinicopathological prospective study. Acta Neurol Scand. 2019 Jan; 139 (1):76-81 Epub 2018 Oct 07
View PubMed
Driver-Dunckley ED, Zhang N, Adler CH, Serrano GE, Sue LI, Shill HA, Mehta SH, Belden CM, Zamrini EY, Davis K, Beach TG. Brain Lewy-Type Synucleinopathy Density Is Associated with a Lower Prevalence of Atherosclerotic Cardiovascular Disease Risk Factors in Patients with Parkinson's Disease1. J Parkinsons Dis. 2019; 9 (3):543-552
View PubMed
Black KJ, Nasrallah H, Isaacson S, Stacy M, Pahwa R, Adler CH, Alva G, Cooney JW, Kremens D, Menza MA, Meyer JM, Patkar AA, Simuni T, Morrissette DA, Stahl SM. Guidance for switching from off-label antipsychotics to pimavanserin for Parkinson's disease psychosis: an expert consensus. CNS Spectr. 2018 Dec; 23 (6):402-413
View PubMed
Hoogland J, van Wanrooij LL, Boel JA, Goldman JG, Stebbins GT, Dalrymple-Alford JC, Marras C, Adler CH, Junque C, Pedersen KF, Mollenhauer B, Zabetian CP, Eslinger PJ, Lewis SJG, Wu RM, Klein M, Rodriguez-Oroz MC, Cammisuli DM, Barone P, Biundo R, de Bie RMA, Schmand BA, Troster AI, Burn DJ, Litvan I, Filoteo JV, Geurtsen GJ, Weintraub D, IPMDS Study Group "Validation of Mild Cognitive Impairment in Parkinson Disease". Detecting Mild Cognitive Deficits in Parkinson's Disease: Comparison of Neuropsychological Tests. Mov Disord. 2018 Nov; 33 (11):1750-1759 Epub 2018 Sept 14
View PubMed
Adler CH, Temkit M, Crews D, McDaniel T, Tucker J, Hentz JG, Marquardt C, Abraham D, Caviness JN. The Yips: Methods to Identify Golfers with a Dystonic Etiology/Golfer's Cramp. Med Sci Sports Exerc. 2018 Nov; 50 (11):2226-2230
View PubMed
Beach TG, Adler CH. Importance of low diagnostic Accuracy for early Parkinson's disease. Mov Disord. 2018 Oct; 33 (10):1551-1554 Epub 2018 Oct 04
View PubMed
Berg D, Adler CH, Bloem BR, Chan P, Gasser T, Goetz CG, Halliday G, Lang AE, Lewis S, Li Y, Liepelt-Scarfone I, Litvan I, Marek K, Maetzler C, Mi T, Obeso J, Oertel W, Olanow CW, Poewe W, Rios-Romenets S, Schaffer E, Seppi K, Heim B, Slow E, Stern M, Bledsoe IO, Deuschl G, Postuma RB. Movement disorder society criteria for clinically established early Parkinson's disease. Mov Disord. 2018 Oct; 33 (10):1643-1646 Epub 2018 Aug 25
View PubMed
Dong X, Liao Z, Gritsch D, Hadzhiev Y, Bai Y, Locascio JJ, Guennewig B, Liu G, Blauwendraat C, Wang T, Adler CH, Hedreen JC, Faull RLM, Frosch MP, Nelson PT, Rizzu P, Cooper AA, Heutink P, Beach TG, Mattick JS, Muller F, Scherzer CR. Enhancers active in dopamine neurons are a primary link between genetic variation and neuropsychiatric disease. Nat Neurosci. 2018 Oct; 21 (10):1482-1492 Epub 2018 Sept 17
View PubMed
Shprecher DR, Adler CH, Zhang N, Hentz JG, Serrano GE, Dugger BN, Shill HA, Savica R, Caviness JN, Sabbagh MN, Belden CM, Driver-Dunckley E, Mehta SH, Sue LI, Davis KJ, Zamrini E, Beach TG. Predicting alpha-synuclein pathology by REM sleep behavior disorder diagnosis. Parkinsonism Relat Disord. 2018 Oct; 55:92-96 Epub 2018 May 17
View PubMed
Ortuno-Lizaran I, Esquiva G, Beach TG, Serrano GE, Adler CH, Lax P, Cuenca N. Degeneration of human photosensitive retinal ganglion cells may explain sleep and circadian rhythms disorders in Parkinson's disease. Acta Neuropathol Commun. 2018 Sep 10; 6 (1):90 Epub 2018 Sept 10
View PubMed
Smith D, Lott D, Beach TG, Serrano GE, Kremer T, Canamero M, Dziadek S, Sade H, Derkinderen P, Corbille AG, Letournel F, Munoz DG, White CL 3rd, Schneider J, Crary JF, Sue LI, Adler CH, Glass MJ, Intorcia AJ, Walker JE, Foroud T, Coffey CS, Ecklund D, Riss H, Gossmann J, Konig F, Kopil CM, Arnedo V, Riley L, Linder C, Dave KD, Jennings D, Seibyl J, Mollenhauer B, Chahine L, Systemic Synuclein Sampling Study (S4). Immunohistochemical Method and Histopathology Judging for the Systemic Synuclein Sampling Study (S4). J Neuropathol Exp Neurol. 2018 Sep 1; 77 (9):793-802
View PubMed
Caviness JN, Beach TG, Hentz JG, Shill HA, Driver-Dunckley ED, Adler CH. Association Between Pathology and Electroencephalographic Activity in Parkinson's Disease. Clin EEG Neurosci. 2018 Sep; 49 (5):321-327 Epub 2017 Feb 01
View PubMed
Claassen DO, Adler CH, Hewitt LA, Gibbons C. Characterization of the symptoms of neurogenic orthostatic hypotension and their impact from a survey of patients and caregivers. BMC Neurol. 2018 Aug 25; 18 (1):125
View PubMed
Ludlow CL, Domangue R, Sharma D, Jinnah HA, Perlmutter JS, Berke G, Sapienza C, Smith ME, Blumin JH, Kalata CE, Blindauer K, Johns M, Hapner E, Harmon A, Paniello R, Adler CH, Crujido L, Lott DG, Bansberg SF, Barone N, Drulia T, Stebbins G. Consensus-Based Attributes for Identifying Patients With Spasmodic Dysphonia and Other Voice Disorders. JAMA Otolaryngol Head Neck Surg. 2018 Aug 1; 144 (8):657-665
View PubMed
Ortuno-Lizaran I, Beach TG, Serrano GE, Walker DG, Adler CH, Cuenca N. Phosphorylated alpha-synuclein in the retina is a biomarker of Parkinson's disease pathology severity. Mov Disord. 2018 Aug; 33 (8):1315-1324 Epub 2018 May 08
View PubMed
Gupta HV, Mehta SH, Zhang N, Hentz JG, Shill HA, Driver-Dunckley E, Sabbagh MN, Belden CM, Dugger BN, Beach TG, Serrano GE, Sue LI, Davis K, Adler CH. Are Clinical Certainty Ratings Helpful in the Diagnosis of Parkinson's Disease? Mov Disord Clin Pract. 2018 Mar-Apr; 5 (2):165-170 Epub 2018 Feb 22
View PubMed
Isaacson SH, Fahn S, Pahwa R, Tanner CM, Espay AJ, Trenkwalder C, Adler CH, Patni R, Johnson R. Parkinson's Patients with Dyskinesia Switched from Immediate Release Amantadine to Open-label ADS-5102. Mov Disord Clin Pract. 2018 Mar-Apr; 5 (2):183-190 Epub 2018 Feb 23
View PubMed
Park HJ, Lee KW, Oh S, Yan R, Zhang J, Beach TG, Adler CH, Voronkov M, Braithwaite SP, Stock JB, Mouradian MM. Protein Phosphatase 2A and Its Methylation Modulating Enzymes LCMT-1 and PME-1 Are Dysregulated in Tauopathies of Progressive Supranuclear Palsy and Alzheimer Disease. J Neuropathol Exp Neurol. 2018 Feb 1; 77 (2):139-148
View PubMed
Chahine LM, Beach TG, Seedorff N, Caspell-Garcia C, Coffey CS, Brumm M, Adler CH, Serrano GE, Linder C, Mosovsky S, Foroud T, Riss H, Ecklund D, Seibyl J, Jennings D, Arnedo V, Riley L, Dave KD, Mollenhauer B, Systemic sSynuclein Sampling study. Feasibility and Safety of Multicenter Tissue and Biofluid Sampling for alpha-Synuclein in Parkinson's Disease: The Systemic Synuclein Sampling Study (S4). J Parkinsons Dis. 2018; 8 (4):517-527
View PubMed
Dong X, Liao Z, Gritsch D, Hadzhiev Y, Bai Y, Locascio JJ, Guennewig B, Liu G, Blauwendraat C, Wang T, Adler CH, Hedreen JC, Faull RLM, Frosch MP, Nelson PT, Rizzu P, Cooper AA, Heutink P, Beach TG, Mattick JS, Scherzer CR. Erratum to: Enhancers active in dopamine neurons are a primary link between genetic variation and neuropsychiatric disease (Nature Neuroscience, (2018), 21, 10, (1482-1492), 10.1038/s41593-018-0223-0) Nature Neuroscience. 2018; 22 (1):144-7
DiBaise JK, Crowell MD, Driver-Dunckley E, Mehta SH, Hoffman-Snyder C, Lin T, Adler CH. Weight Loss in Parkinson's Disease: No Evidence for Role of Small Intestinal Bacterial Overgrowth. J Parkinsons Dis. 2018; 8 (4):571-581
View PubMed
Lionnet A, Leclair-Visonneau L, Neunlist M, Murayama S, Takao M, Adler CH, Derkinderen P, Beach TG. Does Parkinson's disease start in the gut? Acta Neuropathol. 2018 Jan; 135 (1):1-12 Epub 2017 Oct 16
View PubMed
Adler CH, Beach TG, Shill HA, Caviness JN, Driver-Dunckley E, Sabbagh MN, Patel A, Sue LI, Serrano G, Jacobson SA, Davis K, Belden CM, Dugger BN, Paciga SA, Winslow AR, Hirst WD, Hentz JG. GBA mutations in Parkinson disease: earlier death but similar neuropathological features. Eur J Neurol. 2017 Nov; 24 (11):1363-1368 Epub 2017 Aug 17
View PubMed
Aslam S, Zhang N, Adler CH, Caviness JN, Driver-Dunckley E, Mehta SH, Sabbagh MN, Belden C, Zamrini E, Beach TG, Shill HA. Essential tremor and depression. Mov Disord Clin Pract. 2017 Nov-Dec; 4 (6):838-842 Epub 2017 July 17
View PubMed
Hintze JM, Ludlow CL, Bansberg SF, Adler CH, Lott DG. Spasmodic Dysphonia: A Review. Part 2: Characterization of Pathophysiology. Otolaryngol Head Neck Surg. 2017 Oct; 157(4):558-564. Epub 2017 Aug 29.
View PubMed
Hintze JM, Ludlow CL, Bansberg SF, Adler CH, Lott DG. Spasmodic Dysphonia: A Review. Part 1: Pathogenic Factors. Otolaryngol Head Neck Surg. 2017 Oct; 157(4):551-557. Epub 2017 Aug 29.
View PubMed
Gerkin RC, Adler CH, Hentz JG, Shill HA, Driver-Dunckley E, Mehta SH, Sabbagh MN, Caviness JN, Dugger BN, Serrano G, Belden C, Smith BH, Sue L, Davis KJ, Zamrini E, Beach TG. Improved diagnosis of Parkinson's disease from a detailed olfactory phenotype. Ann Clin Transl Neurol. 2017 Oct; 4 (10):714-721 Epub 2017 Sept 08
View PubMed
Hoogland J, Boel JA, de Bie RMA, Geskus RB, Schmand BA, Dalrymple-Alford JC, Marras C, Adler CH, Goldman JG, Troster AI, Burn DJ, Litvan I, Geurtsen GJ, MDS Study Group "Validation of Mild Cognitive Impairment in Parkinson Disease". Mild cognitive impairment as a risk factor for Parkinson's disease dementia. Mov Disord. 2017 Jul; 32 (7):1056-1065 Epub 2017 June 12
View PubMed
Dashtipour K, Tafreshi A, Adler C, Beach T, Chen X, Serrano G, Tashiro S, Wang C. Hypermethylation of Synphilin-1, Alpha-Synuclein-Interacting Protein (SNCAIP) Gene in the Cerebral Cortex of Patients with Sporadic Parkinson's Disease. Brain Sci. 2017 Jun 27; 7 (7) Epub 2017 June 27
View PubMed
Walker DG, Lue LF, Tang TM, Adler CH, Caviness JN, Sabbagh MN, Serrano GE, Sue LI, Beach TG. Changes in CD200 and intercellular adhesion molecule-1 (ICAM-1) levels in brains of Lewy body disorder cases are associated with amounts of Alzheimer's pathology not alpha-synuclein pathology. Neurobiol Aging. 2017 Jun; 54:175-186 Epub 2017 Mar 16
View PubMed
Trosch RM, Espay AJ, Truong D, Gil R, Singer C, LeWitt PA, Lew MF, Tagliati M, Adler CH, Chen JJ, Marchese D, Comella CL. Multicenter observational study of abobotulinumtoxinA neurotoxin in cervical dystonia: The ANCHOR-CD registry. J Neurol Sci. 2017 May 15; 376:84-90 Epub 2017 Feb 21
View PubMed
Adler CH, Dugger BN, Hentz JG, Hinni ML, Lott DG, Driver-Dunckley E, Mehta S, Serrano G, Sue LI, Duffy A, Intorcia A, Filon J, Pullen J, Walker DG, Beach TG. Peripheral synucleinopathy in early Parkinson's disease: Submandibular gland needle biopsy findings. Mov Disord. 2017 May; 32: (5)722-723.
View PubMed
Visanji NP, Mollenhauer B, Beach TG, Adler CH, Coffey CS, Kopil CM, Dave KD, Foroud T, Chahine L, Jennings D, Systemic Synuclein Sampling Study (S4). The Systemic Synuclein Sampling Study: toward a biomarker for Parkinson's disease. Biomark Med. 2017 Apr; 11 (4):359-368 Epub 2017 Mar 29
View PubMed
Pal GD, Ouyang B, Serrano G, Shill HA, Goetz C, Stebbins G, Metman LV, Driver-Dunckley E, Mehta SH, Caviness JN, Sabbagh MN, Adler CH, Beach TG, Arizona Study of Aging Neurodegenerative Disorders. Comparison of neuropathology in Parkinson's disease subjects with and without deep brain stimulation. Mov Disord. 2017 Feb; 32 (2):274-277 Epub 2016 Dec 02
View PubMed
Lee JM, Derkinderen P, Kordower JH, Freeman R, Munoz DG, Kremer T, Zago W, Hutten SJ, Adler CH, Serrano GE, Beach TG. The Search for a Peripheral Biopsy Indicator of alpha-Synuclein Pathology for Parkinson Disease. J Neuropathol Exp Neurol. 2017 Jan 1; 76 (1):2-15
View PubMed
Hopfner F, Haubenberger D, Galpern WR, Gwinn K, Van't Veer A, White S, Bhatia K, Adler CH, Eidelberg D, Ondo W, Stebbins GT, Tanner CM, Helmich RC, Lenz FA, Sillitoe RV, Vaillancourt D, Vitek JL, Louis ED, Shill HA, Frosch MP, Foroud T, Kuhlenbaumer G, Singleton A, Testa CM, Hallett M, Elble R, Deuschl G. Knowledge gaps and research recommendations for essential tremor. Parkinsonism Relat Disord. 2016 Dec; 33:27-35 Epub 2016 Oct 04
View PubMed
Postuma RB, Berg D, Stern M, Poewe W, Olanow CW, Oertel W, Marek K, Litvan I, Lang AE, Halliday G, Goetz CG, Gasser T, Dubois B, Chan P, Bloem BR, Adler CH, Deuschl G. Abolishing the 1-year rule: How much evidence will be enough? Mov Disord. 2016 Nov; 31 (11):1623-1627 Epub 2016 Sept 26
View PubMed
Beach TG, Corbille AG, Letournel F, Kordower JH, Kremer T, Munoz DG, Intorcia A, Hentz J, Adler CH, Sue LI, Walker J, Serrano G, Derkinderen P. Multicenter Assessment of Immunohistochemical Methods for Pathological Alpha-Synuclein in Sigmoid Colon of Autopsied Parkinson's Disease and Control Subjects. J Parkinsons Dis. 2016 Oct 19; 6 (4):761-770
View PubMed
Park HJ, Lee KW, Park ES, Oh S, Yan R, Zhang J, Beach TG, Adler CH, Voronkov M, Braithwaite SP, Stock JB, Mouradian MM. Dysregulation of protein phosphatase 2A in parkinson disease and dementia with lewy bodies. Ann Clin Transl Neurol. 2016 Oct; 3 (10):769-780 Epub 2016 Sept 07
View PubMed
Adler CH, Beach TG. Neuropathological basis of nonmotor manifestations of Parkinson's disease. Mov Disord. 2016 Aug; 31 (8):1114-9 Epub 2016 Mar 31
View PubMed
Filon JR, Intorcia AJ, Sue LI, Vazquez Arreola E, Wilson J, Davis KJ, Sabbagh MN, Belden CM, Caselli RJ, Adler CH, Woodruff BK, Rapscak SZ, Ahern GL, Burke AD, Jacobson S, Shill HA, Driver-Dunckley E, Chen K, Reiman EM, Beach TG, Serrano GE. Gender Differences in Alzheimer Disease: Brain Atrophy, Histopathology Burden, and Cognition. J Neuropathol Exp Neurol. 2016 Aug; 75 (8):748-754 Epub 2016 June 12
View PubMed
Caviness JN, Lue LF, Hentz JG, Schmitz CT, Adler CH, Shill HA, Sabbagh MN, Beach TG, Walker DG. Cortical phosphorylated alpha-Synuclein levels correlate with brain wave spectra in Parkinson's disease. Mov Disord. 2016 Jul; 31 (7):1012-9 Epub 2016 Apr 08
View PubMed
Henderson-Smith A, Corneveaux JJ, De Both M, Cuyugan L, Liang WS, Huentelman M, Adler C, Driver-Dunckley E, Beach TG, Dunckley TL. Next-generation profiling to identify the molecular etiology of Parkinson dementia. Neurol Genet. 2016 Jun; 2 (3):e75 Epub 2016 May 24
View PubMed
Adler CH, Hentz JG, Beach TG. Assessing medication role on neuropathological findings in Parkinson's disease. Mov Disord 2016 May; 31 (5):613-4 Epub 2016 Feb 16
View PubMed
Utianski RL, Caviness JN, van Straaten EC, Beach TG, Dugger BN, Shill HA, Driver-Dunckley ED, Sabbagh MN, Mehta S, Adler CH, Hentz JG. Graph theory network function in Parkinson's disease assessed with electroencephalography. Clin Neurophysiol. 2016 May; 127: (5)2228-36.
View PubMed
Comella CL, Perlmutter JS, Jinnah HA, Waliczek TA, Rosen AR, Galpern WR, Adler CA, Barbano RL, Factor SA, Goetz CG, Jankovic J, Reich SG, Rodriguez RL, Severt WL, Zurowski M, Fox SH, Stebbins GT. Clinimetric testing of the comprehensive cervical dystonia rating scale. Mov Disord. 2016 Apr; 31 (4):563-9 Epub 2016 Mar 12
View PubMed
Molho ES, Stacy M, Gillard P, Charles D, Adler CH, Jankovic J, Schwartz M, Brin MF. Impact of Cervical Dystonia on Work Productivity: An Analysis From a Patient Registry. Mov Disord Clin Pract. 2016 Mar-Apr; 3 (2):130-138 Epub 2015 Dec 16
View PubMed
Toledo JB, Gopal P, Raible K, Irwin DJ, Brettschneider J, Sedor S, Waits K, Boluda S, Grossman M, Van Deerlin VM, Lee EB, Arnold SE, Duda JE, Hurtig H, Lee VM, Adler CH, Beach TG, Trojanowski JQ. Pathological alpha-synuclein distribution in subjects with coincident Alzheimer's and Lewy body pathology. Acta Neuropathol. 2016 Mar; 131 (3):393-409 Epub 2015 Dec 31
View PubMed
Caviness JN, Utianski RL, Hentz JG, Beach TG, Dugger BN, Shill HA, Driver-Dunckley ED, Sabbagh MN, Mehta S, Adler CH. Differential spectral quantitative electroencephalography patterns between control and Parkinson's disease cohorts. Eur J Neurol. 2016 Feb; 23 (2):387-92 Epub 2015 Oct 31
View PubMed
Adler CH, Dugger BN, Hentz JG, Hinni ML, Lott DG, Driver-Dunckley E, Mehta S, Serrano G, Sue LI, Duffy A, Intorcia A, Filon J, Pullen J, Walker DG, Beach TG. Peripheral Synucleinopathy in Early Parkinson's Disease: Submandibular Gland Needle Biopsy Findings. Mov Disord. 2016 Feb; 31 (2):250-6 Epub 2016 Jan 22
View PubMed
Lue LF, Schmitz CT, Snyder NL, Chen K, Walker DG, Davis KJ, Belden C, Caviness JN, Driver-Dunckley E, Adler CH, Sabbagh MN, Shill HA. Converging mediators from immune and trophic pathways to identify Parkinson disease dementia. Neurol Neuroimmunol Neuroinflamm. 2016 Feb; 3 (1):e193 Epub 2016 Jan 27
View PubMed
Beach TG, Adler CH, Serrano G, Sue LI, Walker DG, Dugger BN, Shill HA, Driver-Dunckley E, Caviness JN, Intorcia A, Filon J, Scott S, Garcia A, Hoffman B, Belden CM, Davis KJ, Sabbagh MN, Arizona Parkinson's Disease Consortium. Prevalence of Submandibular Gland Synucleinopathy in Parkinson's Disease, Dementia with Lewy Bodies and other Lewy Body Disorders. J Parkinsons Dis. 2016; 6 (1):153-63
View PubMed
Mehta SH, Adler CH. Advances in Biomarker Research in Parkinson's Disease. Curr Neurol Neurosci Rep. 2016 Jan; 16 (1):7
View PubMed
Biglan KM, Shoulson I, Kieburtz K, Oakes D, Kayson E, Shinaman MA, Zhao H, Romer M, Young A, Hersch S, Penney J, Marder K, Paulsen J, Quaid K, Siemers E, Tanner C, Mallonee W, Suter G, Dubinsky R, Gray C, Nance M, Bundlie S, Radtke D, Kostyk S, Baic C, Caress J, Walker F, Hunt V, O'Neill C, Chouinard S, Factor S, Greenamyre T, Wood-Siverio C, Corey-Bloom J, Song D, Peavy G, Moskowitz C, Wesson M, Samii A, Bird T, Lipe H, Blindauer K, Marshall F, Zimmerman C, Goldstein J, Rosas D, Novak P, Caviness J, Adler C, Duffy A, Wheelock V, Tempkin T, Richman D, Seeberger L, Albin R, Chou KL, Racette B, Perlmutter JS, Perlman S, Bordelon Y, Martin W, Wieler M, Leavitt B, Raymond L, Decolongon J, Clarke L, Jankovic J, Hunter C, Hauser RA, Sanchez-Ramos J, Furtado S, Suchowersky O, Klimek ML, Guttman M, Sethna R, Feigin A, Cox M, Shannon B, Percy A, Dure L, Harrison M, Johnson W, Higgins D, Molho E, Nickerson C, Evans S, Hobson D, Singer C, Galvez-Jimenez N, Shannon K, Comella C, Ross C, Saint-Hilaire MH, Testa C, Rosenblatt A, Hogarth P, Weiner W, Como P, Kumar R, Cotto C, Stout J, Brocht A, Watts A, Eberly S, Weaver C, Foroud T, Gusella J, MacDonald M, Myers R, Fahn S, Shults C, Huntington Study Group PHAROS Investigators. Clinical-Genetic Associations in the Prospective Huntington at Risk Observational Study (PHAROS): Implications for Clinical Trials. JAMA Neurol. 2016 Jan; 73 (1):102-10
View PubMed
Shill HA, Hentz JG, Caviness JN, Driver-Dunckley E, Jacobson S, Belden C, Sabbagh MN, Beach TG, Adler CH. Unawareness of Hyposmia in Elderly People With and Without Parkinson's Disease. Mov Disord Clin Pract. 2016 Jan-Feb; 3 (1):43-47 Epub 2015 July 17
View PubMed
Hentz JG, Mehta SH, Shill HA, Driver-Dunckley E, Beach TG, Adler CH. Simplified conversion method for unified Parkinson's disease rating scale motor examinations. Mov Disord. 2015 Dec; 30 (14):1967-70 Epub 2015 Nov 17
View PubMed
Janelidze S, Lindqvist D, Francardo V, Hall S, Zetterberg H, Blennow K, Adler CH, Beach TG, Serrano GE, van Westen D, Londos E, Cenci MA, Hansson O. Increased CSF biomarkers of angiogenesis in Parkinson disease. Neurology. 2015 Nov 24; 85 (21):1834-42 Epub 2015 Oct 28
View PubMed
Iacono D, Geraci-Erck M, Rabin ML, Adler CH, Serrano G, Beach TG, Kurlan R. Parkinson disease and incidental Lewy body disease: Just a question of time? Neurology. 2015 Nov 10; 85 (19):1670-9 Epub 2015 Oct 14
View PubMed
Labbe C, Ogaki K, Lorenzo-Betancor O, Soto-Ortolaza AI, Walton RL, Rayaprolu S, Fujioka S, Murray ME, Heckman MG, Puschmann A, McCarthy A, Lynch T, Siuda J, Opala G, Rudzinska M, Krygowska-Wajs A, Barcikowska M, Czyzewski K, Sanotsky Y, Rektorova I, McLean PJ, Rademakers R, Ertekin-Taner N, Hassan A, Ahlskog JE, Boeve BF, Petersen RC, Maraganore DM, Adler CH, Ferman TJ, Parisi JE, Graff-Radford NR, Uitti RJ, Wszolek ZK, Dickson DW, Ross OA. Role for the microtubule-associated protein tau variant p.A152T in risk of alpha-synucleinopathies. Neurology. 2015 Nov 10; 85 (19):1680-6 Epub 2015 Sept 02
View PubMed
Labbe C, Ogaki K, Lorenzo-Betancor O, Soto-Ortolaza AI, Walton RL, Rayaprolu S, Fujioka S, Murray ME, Heckman MG, Puschmann A, McCarthy A, Lynch T, Siuda J, Opala G, Rudzinska M, Krygowska-Wajs A, Barcikowska M, Czyzewski K, Sanotsky Y, Rektorova I, McLean PJ, Rademakers R, Ertekin-Taner N, Hassan A, Ahlskog JE, Boeve BF, Petersen RC, Maraganore DM, Adler CH, Ferman TJ, Parisi JE, Graff-Radford NR, Uitti RJ, Wszolek ZK, Dickson DW, Ross OA. "Role for the microtubule-associated protein tau variant p.A152T in risk of alpha-synucleinopathies": Correction Neurology. 2015 Nov; 85: (19)1728.
Patel AB, Bansberg SF, Adler CH, Lott DG, Crujido L. The Mayo Clinic Arizona Spasmodic Dysphonia Experience: A Demographic Analysis of 718 Patients. Ann Otol Rhinol Laryngol. 2015 Nov; 124 (11):859-63 Epub 2015 May 29
View PubMed
Berg D, Postuma RB, Adler CH, Bloem BR, Chan P, Dubois B, Gasser T, Goetz CG, Halliday G, Joseph L, Lang AE, Liepelt-Scarfone I, Litvan I, Marek K, Obeso J, Oertel W, Olanow CW, Poewe W, Stern M, Deuschl G. MDS research criteria for prodromal Parkinson's disease. Mov Disord. 2015 Oct; 30 (12):1600-11
View PubMed
Postuma RB, Berg D, Stern M, Poewe W, Olanow CW, Oertel W, Obeso J, Marek K, Litvan I, Lang AE, Halliday G, Goetz CG, Gasser T, Dubois B, Chan P, Bloem BR, Adler CH, Deuschl G. MDS clinical diagnostic criteria for Parkinson's disease. Mov Disord. 2015 Oct; 30 (12):1591-601
View PubMed
Serrano GE, Intorcia A, Carew J, Chiarolanza G, Hidalgo JA, Sue LI, Dugger BN, Saxon-LaBelle M, Filon J, Scroggins A, Pullen J, Fornwalt BE, Scott S, Sabbagh MN, Adler CH, Akiyama H, Beach TG. Feasibility Study: Comparison of Frontal Cortex Needle Core Versus Open Biopsy for Detection of Characteristic Proteinopathies of Neurodegenerative Diseases. J Neuropathol Exp Neurol. 2015 Sep; 74 (9):934-42
View PubMed
Postuma RB, Adler CH, Dugger BN, Hentz JG, Shill HA, Driver-Dunckley E, Sabbagh MN, Jacobson SA, Belden CM, Sue LI, Serrano G, Beach TG. REM sleep behavior disorder and neuropathology in Parkinson's disease. Mov Disord. 2015 Sep; 30 (10):1413-7 Epub 2015 Aug 12
View PubMed
Dugger BN, Davis K, Malek-Ahmadi M, Hentz JG, Sandhu S, Beach TG, Adler CH, Caselli RJ, Johnson TA, Serrano GE, Shill HA, Belden C, Driver-Dunckley E, Caviness JN, Sue LI, Jacobson S, Powell J, Sabbagh MN. Neuropathological comparisons of amnestic and nonamnestic mild cognitive impairment. BMC Neurol. 2015 Aug 20; 15:146
View PubMed
Mu LC, Chen JM, Sobotka S, Nyirenda T, Benson B, Gupta F, Sanders I, Adler CH, Caviness JN, Shill HA, Sabbagh M, Samanta JE, Sue LI, Beach TG. Alpha-synuclein pathology in sensory nerve terminals of the upper aerodigestive tract of Parkinson's disease patients. Dysphagia. 2015 Aug; 30(4):404-17.
View PubMed
Beach TG, Adler CH, Sue LI, Serrano G, Shill HA, Walker DG, Lue L, Roher AE, Dugger BN, Maarouf C, Birdsill AC, Intorcia A, Saxon-Labelle M, Pullen J, Scroggins A, Filon J, Scott S, Hoffman B, Garcia A, Caviness JN, Hentz JG, Driver-Dunckley E, Jacobson SA, Davis KJ, Belden CM, Long KE, Malek-Ahmadi M, Powell JJ, Gale LD, Nicholson LR, Caselli RJ, Woodruff BK, Rapscak SZ, Ahern GL, Shi J, Burke AD, Reiman EM, Sabbagh MN. Arizona Study of Aging and Neurodegenerative Disorders and Brain and Body Donation Program. Neuropathology. 2015 Aug; 35 (4):354-89 Epub 2015 Jan 26
View PubMed
Rigby HB, Dugger BN, Hentz JG, Adler CH, Beach TG, Shill HA, Driver-Dunckley E, Sabbagh MN, Sue LI, Caviness JN. Clinical Features of Patients with Concomitant Parkinson's Disease and Progressive Supranuclear Palsy Pathology. Mov Disord Clin Pract. 2015 Mar; 2 (1):33-38 Epub 2014 Oct 29
View PubMed
Jankovic J, Adler CH, Charles D, Comella C, Stacy M, Schwartz M, Manack Adams A, Brin MF. Primary results from the cervical dystonia patient registry for observation of onabotulinumtoxina efficacy (CD PROBE). J Neurol Sci. 2015 Feb 15; 349 (1-2):84-93 Epub 2014 Dec 27
View PubMed
Walker DG, Lue LF, Serrano G, Adler CH, Caviness JN, Sue LI, Beach TG. Altered Expression Patterns of Inflammation-Associated and Trophic Molecules in Substantia Nigra and Striatum Brain Samples from Parkinson's Disease, Incidental Lewy Body Disease and Normal Control Cases. Front Neurosci. 2015; 9:507 Epub 2016 Jan 14
View PubMed
Caviness JN, Hentz JG, Belden CM, Shill HA, Driver-Dunckley ED, Sabbagh MN, Powell JJ, Adler CH. Longitudinal EEG changes correlate with cognitive measure deterioration in Parkinson's disease. J Parkinsons Dis. 2015; 5 (1):117-24
View PubMed
Lin TP, Rigby H, Adler JS, Hentz JG, Balcer LJ, Galetta SL, Devick S, Cronin R, Adler CH. Abnormal visual contrast acuity in Parkinson's disease. J Parkinsons Dis. 2015; 5(1):125-30.
View PubMed
Driver-Dunckley E, Adler CH, Hentz JG, Dugger BN, Shill HA, Caviness JN, Sabbagh MN, Beach TG, Arizona Parkinson Disease Consortium. Olfactory dysfunction in incidental Lewy body disease and Parkinson's disease. Parkinsonism Relat Disord. 2014 Nov; 20 (11):1260-2 Epub 2014 Aug 16
View PubMed
Jacobson SA, Morshed T, Dugger BN, Beach TG, Hentz JG, Adler CH, Shill HA, Sabbagh MN, Belden CM, Sue LI, Caviness JN, Hu C, Arizona Parkinson's Disease Consortium. Plaques and tangles as well as Lewy-type alpha synucleinopathy are associated with formed visual hallucinations. Parkinsonism Relat Disord. 2014 Sep; 20 (9):1009-14 Epub 2014 June 28
View PubMed
Adler CH, Beach TG, Hentz JG, Shill HA, Caviness JN, Driver-Dunckley E, Sabbagh MN, Sue LI, Jacobson SA, Belden CM, Dugger BN. Low clinical diagnostic accuracy of early vs advanced Parkinson disease: clinicopathologic study. Neurology. 2014 Jul 29; 83 (5):406-12 Epub 2014 June 27
View PubMed
Kellie JF, Higgs RE, Ryder JW, Major A, Beach TG, Adler CH, Merchant K, Knierman MD. Quantitative measurement of intact alpha-synuclein proteoforms from post-mortem control and Parkinson's disease brain tissue by intact protein mass spectrometry. Sci Rep. 2014 Jul 23; 4:5797 Epub 2014 July 23
View PubMed
Beach TG, Carew J, Serrano G, Adler CH, Shill HA, Sue LI, Sabbagh MN, Akiyama H, Cuenca N, Arizona Parkinson's Disease Consortium. Phosphorylated alpha-synuclein-immunoreactive retinal neuronal elements in Parkinson's disease subjects. Neurosci Lett. 2014 Jun 13; 571:34-8 Epub 2014 Apr 28
View PubMed
Dugger BN, Adler CH, Shill HA, Caviness J, Jacobson S, Driver-Dunckley E, Beach TG, Arizona Parkinson's Disease Consortium. Concomitant pathologies among a spectrum of parkinsonian disorders. Parkinsonism Relat Disord. 2014 May; 20 (5):525-9 Epub 2014 Feb 22
View PubMed
Beal MF, Oakes D, Shoulson I, Henchcliffe C, Galpern WR, Haas R, Juncos JL, Nutt JG, Voss TS, Ravina B, Shults CM, Helles K, Snively V, Lew MF, Griebner B, Watts A, Gao S, Pourcher E, Bond L, Kompoliti K, Agarwal P, Sia C, Jog M, Cole L, Sultana M, Kurlan R, Richard I, Deeley C, Waters CH, Figueroa A, Arkun A, Brodsky M, Ondo WG, Hunter CB, Jimenez-Shahed J, Palao A, Miyasaki JM, So J, Tetrud J, Reys L, Smith K, Singer C, Blenke A, Russell DS, Cotto C, Friedman JH, Lannon M, Zhang L, Drasby E, Kumar R, Subramanian T, Ford DS, Grimes DA, Cote D, Conway J, Siderowf AD, Evatt ML, Sommerfeld B, Lieberman AN, Okun MS, Rodriguez RL, Merritt S, Swartz CL, Martin WR, King P, Stover N, Guthrie S, Watts RL, Ahmed A, Fernandez HH, Winters A, Mari Z, Dawson TM, Dunlop B, Feigin AS, Shannon B, Nirenberg MJ, Ogg M, Ellias SA, Thomas CA, Frei K, Bodis-Wollner I, Glazman S, Mayer T, Hauser RA, Pahwa R, Langhammer A, Ranawaya R, Derwent L, Sethi KD, Farrow B, Prakash R, Litvan I, Robinson A, Sahay A, Gartner M, Hinson VK, Markind S, Pelikan M, Perlmutter JS, Hartlein J, Molho E, Evans S, Adler CH, Duffy A, Lind M, Elmer L, Davis K, Spears J, Wilson S, Leehey MA, Hermanowicz N, Niswonger S, Shill HA, Obradov S, Rajput A, Cowper M, Lessig S, Song D, Fontaine D, Zadikoff C, Williams K, Blindauer KA, Bergholte J, Propsom CS, Stacy MA, Field J, Mihaila D, Chilton M, Uc EY, Sieren J, Simon DK, Kraics L, Silver A, Boyd JT, Hamill RW, Ingvoldstad C, Young J, Thomas K, Kostyk SK, Wojcieszek J, Pfeiffer RF, Panisset M, Beland M, Reich SG, Cines M, Zappala N, Rivest J, Zweig R, Lumina LP, Hilliard CL, Grill S, Kellermann M, Tuite P, Rolandelli S, Kang UJ, Young J, Rao J, Cook MM, Severt L, Boyar K, Parkinson Study Group QE3 Investigators. A randomized clinical trial of high-dosage coenzyme Q10 in early Parkinson disease: no evidence of benefit. JAMA Neurol. 2014 May; 71 (5):543-52
View PubMed
Adler CH, Dugger BN, Hinni ML, Lott DG, Driver-Dunckley E, Hidalgo J, Henry-Watson J, Serrano G, Sue LI, Nagel T, Duffy A, Shill HA, Akiyama H, Walker DG, Beach TG. Submandibular gland needle biopsy for the diagnosis of Parkinson disease. Neurology. 2014 Mar 11; 82 (10):858-64 Epub 2014 Feb 05
View PubMed
Dugger BN, Hentz JG, Adler CH, Sabbagh MN, Shill HA, Jacobson S, Caviness JN, Belden C, Driver-Dunckley E, Davis KJ, Sue LI, Beach TG. Clinicopathological outcomes of prospectively followed normal elderly brain bank volunteers. J Neuropathol Exp Neurol. 2014 Mar; 73 (3):244-52
View PubMed
Lin TP, Adler CH, Hentz JG, Balcer LJ, Galetta SL, Devick S. Slowing of number naming speed by King-Devick test in Parkinson's disease. Parkinsonism Relat Disord. 2014 Feb; 20 (2):226-9 Epub 2013 Oct 18
View PubMed
Siderowf A, Pontecorvo MJ, Shill HA, Mintun MA, Arora A, Joshi AD, Lu M, Adler CH, Galasko D, Liebsack C, Skovronsky DM, Sabbagh MN. PET imaging of amyloid with Florbetapir F 18 and PET imaging of dopamine degeneration with 18F-AV-133 (florbenazine) in patients with Alzheimer's disease and Lewy body disorders. BMC Neurology. 2014; 14(1):79.
View PubMed
Charles PD, Adler CH, Stacy M, Comella C, Jankovic J, Manack Adams A, Schwartz M, Brin MF. Cervical dystonia and pain: Characteristics and treatment patterns from CD PROBE (Cervical Dystonia Patient Registry for Observation of OnabotulinumtoxinA Efficacy). J Neurol. 2014; 261(7):1309-19.
View PubMed
Halliday GM, Leverenz JB, Schneider JS, Adler CH. The neurobiological basis of cognitive impairment in Parkinson's disease. Mov Disord. 2014; 29(5):634-50.
View PubMed
Symanski C, Shill HA, Dugger B, Hentz JG, Adler CH, Jacobson SA, Driver-Dunckley E, Beach TG. Essential tremor is not associated with cerebellar Purkinje cell loss. Mov Disord. 2014; 29(4):496-500.
View PubMed
Burgos K, Malenica I, Metpally R, Courtright A, Rakela B, Beach T, Shill H, Adler C, Sabbagh M, Villa S, Tembe W, Craig D, Van Keuren-Jensen K. Profiles of extracellular miRNA in cerebrospinal fluid and serum from patients with Alzheimer's and Parkinson's diseases correlate with disease status and features of pathology. PLoS One. 2014; 9 (5):e94839 Epub 2014 May 05
View PubMed
Shill HA, Hentz JG, Jacobson SA, Belden C, Sabbagh MN, Beach TG, Driver-Dunckley E, Adler CH. Essential Tremor in the Elderly and Risk for Dementia. J Neurodegener Dis. 2014; 2014:328765 Epub 2014 Apr 09
View PubMed
Shneyder N, Adler CH, Hentz JG, Shill H, Caviness JN, Sabbagh MN, Beach TG, Driver-Dunckley E. Autonomic complaints in patients with restless legs syndrome. Sleep Med. 2013 Dec; 14 (12):1413-6 Epub 2013 Sept 21
View PubMed
Lewitt PA, Li J, Lu M, Beach TG, Adler CH, Guo L, Arizona Parkinson's Disease Consortium. 3-hydroxykynurenine and other Parkinson's disease biomarkers discovered by metabolomic analysis. Mov Disord. 2013 Oct; 28(12):1653-60. Epub 2013 Jul 19.
View PubMed
Kordower JH, Olanow CW, Dodiya HB, Chu Y, Beach TG, Adler CH, Halliday GM, Bartus RT. Disease duration and the integrity of the nigrostriatal system in Parkinson's disease. Brain. 2013 Aug; 136(Pt 8):2419-31.
View PubMed
Boeve BF, Silber MH, Ferman TJ, Lin SC, Benarroch EE, Schmeichel AM, Ahlskog JE, Caselli RJ, Jacobson S, Sabbagh M, Adler C, Woodruff B, Beach TG, Iranzo A, Gelpi E, Santamaria J, Tolosa E, Singer C, Mash DC, Luca C, Arnulf I, Duyckaerts C, Schenck CH, Mahowald MW, Dauvilliers Y, Graff-Radford NR, Wszolek ZK, Parisi JE, Dugger B, Murray ME, Dickson DW. Clinicopathologic correlations in 172 cases of rapid eye movement sleep behavior disorder with or without a coexisting neurologic disorder. Sleep Med. 2013 Aug; 14 (8):754-62 Epub 2013 Mar 07
View PubMed
Mu L, Sobotka S, Chen J, Su H, Sanders I, Nyirenda T, Adler CH, Shill HA, Caviness JN, Samanta JE, Sue LI, Beach TG, the Arizona Parkinson's Disease Consortium. Parkinson disease affects peripheral sensory nerves in the pharynx. J Neuropathol Exp Neurol. 2013 Jul; 72(7):614-23.
View PubMed
Mu L, Sobotka S, Chen J, Su H, Sanders I, Adler CH, Shill HA, Caviness JN, Samanta JE, Beach TG, Arizona Parkinson's Disease Consortium. Alpha-synuclein pathology and axonal degeneration of the peripheral motor nerves innervating pharyngeal muscles in Parkinson disease. J Neuropathol Exp Neurol. 2013 Feb; 72(2):119-29.
View PubMed
Beach TG, Adler CH, Dugger BN, Serrano G, Hidalgo J, Henry-Watson J, Shill HA, Sue LI, Sabbagh MN, Akiyama H, Arizona Parkinson's Disease Consortium. Submandibular gland biopsy for the diagnosis of Parkinson disease. J Neuropathol Exp Neurol. 2013 Feb; 72(2):130-6.
View PubMed
Walker DG, Lue LF, Adler CH, Shill HA, Caviness JN, Sabbagh MN, Akiyama H, Serrano GE, Sue LI, Beach TG, Arizona Parkinson Disease Consortium. Changes in properties of serine 129 phosphorylated alpha-synuclein with progression of Lewy-type histopathology in human brains. Exp Neurol. 2013 Feb; 240:190-204. Epub 2012 Nov 28.
View PubMed
Malek-Ahmadi M, Kahlon V, Adler CH, Obradov A, Thind K, Shill HA, Sue LI, Caviness JN, Jacobson S, Sabbagh MN. Prevalence of Hippocampal Sclerosis in a Clinicopathologically Characterized Cohort. Clin Exp Med Sci. 2013; 1 (7):317-327
View PubMed
Henderson-Smith A, Chow D, Meechoovet B, Aziz M, Jacobson SA, Shill HA, Sabbagh MN, Caviness JN, Adler CH, Driver-Dunckley ED, Beach TG, Yin H, Dunckley T. SMG1 identified as a regulator of Parkinson's disease-associated alpha-synuclein through siRNA screening. PLoS One. 2013; 8: (10)e77711.
View PubMed
Maarouf CL, Beach TG, Adler CH, Malek-Ahmadi M, Kokjohn TA, Dugger BN, Walker DG, Shill HA, Jacobson SA, Sabbagh MN, Roher AE, Arizona Parkinson's Disease Consortium. Quantitative appraisal of ventricular cerebrospinal fluid biomarkers in neuropathologically diagnosed Parkinson's disease cases lacking Alzheimer's disease pathology. Biomark Insights. 2013; 8:19-28 Epub 2013 Mar 12
View PubMed
Damian A, Adler CH, Hentz JG, Shill HA, Caviness JN, Sabbagh MN, Evidente VG, Beach TG, Driver-Dunckley E. Autonomic function, as self-reported on the SCOPA-autonomic questionnaire, is normal in essential tremor but not in Parkinson's disease. Parkinsonism Relat Disord. 2012 Dec; 18: (10)1089-93.
View PubMed
Driver-Dunckley ED, Adler CH. Movement disorders and sleep. Neurol Clin. 2012 Nov; 30(4):1345-58.
View PubMed
Annerino DM, Arshad S, Taylor GM, Adler CH, Beach TG, Greene JG. Parkinson's disease is not associated with gastrointestinal myenteric ganglion neuron loss. Acta Neuropathol. 2012 Nov; 124(5):665-80. Epub 2012 Sep 02.
View PubMed
Lue LF, Walker DG, Adler CH, Shill H, Tran H, Akiyama H, Sue LI, Caviness J, Sabbagh MN, Beach TG. Biochemical increase in phosphorylated alpha-synuclein precedes histopathology of Lewy-type synucleinopathies. Brain Pathol. 2012 Nov; 22(6):745-56. Epub 2012 Apr 12.
View PubMed
Jiang H, He P, Adler CH, Shill H, Beach TG, Li R, Shen Y. Bid signal pathway components are identified in the temporal cortex with Parkinson disease. Neurology. 2012 Oct 23; 79(17):1767-73. Epub 2012 Sep 26.
View PubMed
Maarouf CL, Beach TG, Adler CH, Shill HA, Sabbagh MN, Wu T, Walker DG, Kokjohn TA, Roher AE, Arizona PD Consortium. Cerebrospinal fluid biomarkers of neuropathologically diagnosed Parkinson's disease subjects. Neurol Res. 2012 Sep; 34 (7):669-76
View PubMed
Mu L, Sobotka S, Chen J, Su H, Sanders I, Adler CH, Shill HA, Caviness JN, Samanta JE, Beach TG, Arizona Parkinson's Disease Consortium. Altered pharyngeal muscles in Parkinson disease. J Neuropathol Exp Neurol. 2012 Jun; 71(6):520-30.
View PubMed
Litvan I, Goldman JG, Troster AI, Schmand BA, Weintraub D, Petersen RC, Mollenhauer B, Adler CH, Marder K, Williams-Gray CH, Aarsland D, Kulisevsky J, Rodriguez-Oroz MC, Burn DJ, Barker RA, Emre M. Diagnostic criteria for mild cognitive impairment in Parkinson's disease: Movement Disorder Society Task Force guidelines. Mov Disord. 2012 Mar; 27(3):349-56. Epub 2012 Jan 24.
View PubMed
Dugger BN, Serrano GE, Sue LI, Walker DG, Adler CH, Shill HA, Sabbagh MN, Caviness JN, Hidalgo J, Saxon-Labelle M, Chiarolanza G, Mariner M, Henry-Watson J, Beach TG, the Arizona Parkinson's Disease Consortium. Presence of Striatal Amyloid Plaques in Parkinson's Disease Dementia Predicts Concomitant Alzheimer's Disease: Usefulness for Amyloid Imaging. J Parkinsons Dis. 2012 Jan 1; 2(1):57-65.
View PubMed
Shill HA, Adler CH, Beach TG. Pathology in essential tremor. Parkinsonism Relat Disord. 2012 Jan; 18 Suppl 1:S135-7.
View PubMed
Shill HA, Adler CH, Beach TG, Lue LF, Caviness JN, Sabbagh MN, Sue LI, Walker DG. Brain biochemistry in autopsied patients with essential tremor. Mov Disord. 2012 Jan; 27(1):113-7. Epub 2011 Oct 28.
View PubMed
Caviness JN, Adler CH, Hentz JG, Shill HA, Evidente VG, Driver-Dunckley ED, Sabbagh MN, Sue L, Beach TG. Incidental Lewy body disease: electrophysiological findings suggesting pre-clinical Lewy body disorders. Clin Neurophysiol. 2011 Dec; 122 (12):2426-32 Epub 2011 May 26
View PubMed
Allen RP, Adler CH, Du W, Butcher A, Bregman DB, Earley CJ. Clinical efficacy and safety of IV ferric carboxymaltose (FCM) treatment of RLS: a multi-centred, placebo-controlled preliminary clinical trial. Sleep Med. 2011 Oct; 12(9):906-13. Epub 2011 Oct 05.
View PubMed
Adler CH, Crews D, Kahol K, Santello M, Noble B, Hentz JG, Caviness JN. Are the yips a task-specific dystonia or "golfer's cramp"? Mov Disord. 2011 Sep; 26 (11):1993-6 Epub 2011 June 14
View PubMed
Evidente VG, Premkumar AP, Adler CH, Caviness JN, Driver-Dunckley E, Lyons MK. Medication dose reductions after pallidal versus subthalamic stimulation in patients with Parkinson's disease. Acta Neurol Scand. 2011 Sep; 124(3):211-4. Epub 2010 Oct 25.
View PubMed
Litvan I, Aarsland D, Adler CH, Goldman JG, Kulisevsky J, Mollenhauer B, Rodriguez-Oroz MC, Troster AI, Weintraub D. MDS Task Force on mild cognitive impairment in Parkinson's disease: critical review of PD-MCI. Mov Disord. 2011 Aug 15; 26(10):1814-24. Epub 2011 Jun 09.
View PubMed
Klassen BT, Hentz JG, Shill HA, Driver-Dunckley E, Evidente VG, Sabbagh MN, Adler CH, Caviness JN. Quantitative EEG as a predictive biomarker for Parkinson disease dementia. Neurology. 2011 Jul 12; 77 (2):118-24 Epub 2011 June 01
View PubMed
Caviness JN, Lue LF, Beach TG, Hentz JG, Adler CH, Sue L, Sadeghi R, Driver-Dunckley E, Evidente VG, Sabbagh MN, Shill HA, Walker DG. Parkinson's disease, cortical dysfunction, and alpha-synuclein. Mov Disord. 2011 Jul; 26 (8):1436-42 Epub 2011 May 03
View PubMed
Adler CH, Hentz JG, Shill HA, Sabbagh MN, Driver-Dunckley E, Evidente VG, Jacobson SA, Beach TG, Boeve B, Caviness JN. Probable RBD is increased in Parkinson's disease but not in essential tremor or restless legs syndrome. Parkinsonism Relat Disord. 2011 Jul; 17 (6):456-8 Epub 2011 Apr 08
View PubMed
Evidente VG, Adler CH, Sabbagh MN, Connor DJ, Hentz JG, Caviness JN, Sue LI, Beach TG. Neuropathological findings of PSP in the elderly without clinical PSP: possible incidental PSP? Parkinsonism Relat Disord. 2011 Jun; 17 (5):365-71 Epub 2011 Mar 21
View PubMed
Papay K, Mamikonyan E, Siderowf AD, Duda JE, Lyons KE, Pahwa R, Driver-Dunckley ED, Adler CH, Weintraub D. Patient versus informant reporting of ICD symptoms in Parkinson's disease using the QUIP: validity and variability. Parkinsonism Relat Disord. 2011 Mar; 17: (3)153-5.
View PubMed
Adler CH, Shill HA, Beach TG. Essential tremor and Parkinson's disease: lack of a link. Mov Disord. 2011 Feb 15; 26 (3):372-7 Epub 2011 Jan 31
View PubMed
Caviness JN, Lue L, Adler CH, Walker DG. Parkinson's disease dementia and potential therapeutic strategies. CNS Neurosci Ther. 2011 Feb; 17 (1):32-44 Epub 2010 Dec 28
View PubMed
Adler CH. Premotor symptoms and early diagnosis of Parkinson's disease. Int J Neurosci. 2011; 121 Suppl 2:3-8.
View PubMed
Jankovic J, Adler CH, Charles PD, Comella C, Stacy M, Schwartz M, Sutch SM, Brin MF, Papapetropoulos S. Rationale and design of a prospective study: Cervical Dystonia Patient Registry for Observation of OnaBotulinumtoxinA Efficacy (CD PROBE). BMC Neurol. 2011; 11:140. Epub 2011 Nov 04.
View PubMed
Damian AM, Jacobson SA, Hentz JG, Belden CM, Shill HA, Sabbagh MN, Caviness JN, Adler CH. The Montreal Cognitive Assessment and the mini-mental state examination as screening instruments for cognitive impairment: item analyses and threshold scores. Dement Geriatr Cogn Disord. 2011; 31(2):126-31. Epub 2011 Jan 29.
View PubMed
Zheng B, Liao Z, Locascio JJ, Lesniak KA, Roderick SS, Watt ML, Eklund AC, Zhang-James Y, Kim PD, Hauser MA, Grunblatt E, Moran LB, Mandel SA, Riederer P, Miller RM, Federoff HJ, Wullner U, Papapetropoulos S, Youdim MB, Cantuti-Castelvetri I, Young AB, Vance JM, Davis RL, Hedreen JC, Adler CH, Beach TG, Graeber MB, Middleton FA, Rochet JC, Scherzer CR, Global PD Gene Expression (GPEX) Consortium. PGC-1alpha, a potential therapeutic target for early intervention in Parkinson's disease. Sci Transl Med. 2010 Oct 6; 2(52):52ra73.
View PubMed
Evidente VG, Adler CH. An update on the neurologic applications of botulinum toxins. Curr Neurol Neurosci Rep. 2010 Sep; 10 (5):338-44
View PubMed
Beach TG, Adler CH, Sue LI, Vedders L, Lue L, White Iii CL, Akiyama H, Caviness JN, Shill HA, Sabbagh MN, Walker DG, Arizona Parkinson's Disease Consortium. Multi-organ distribution of phosphorylated alpha-synuclein histopathology in subjects with Lewy body disorders. Acta Neuropathol. 2010 Jun; 119 (6):689-702 Epub 2010 Mar 21
View PubMed
Adler CH, Connor DJ, Hentz JG, Sabbagh MN, Caviness JN, Shill HA, Noble B, Beach TG. Incidental Lewy body disease: clinical comparison to a control cohort. Mov Disord. 2010 Apr 15; 25 (5):642-6
View PubMed
McKinnon J, Evidente V, Driver-Dunckley E, Premkumar A, Hentz J, Shill H, Sabbagh M, Caviness J, Connor D, Adler C. Olfaction in the elderly: a cross-sectional analysis comparing Parkinson's disease with controls and other disorders. Int J Neurosci. 2010 Jan; 120(1):36-9.
View PubMed
Adler CH. Mild cognitive impairment in Parkinson's disease. Parkinsonism Relat Disord. 2009 Dec; 15 Suppl 3:S81-2.
View PubMed
Cobb SA, Wider C, Ross OA, Mata IF, Adler CH, Rajput A, Rajput AH, Wu RM, Hauser R, Josephs KA, Carr J, Gwinn K, Heckman MG, Aasly JO, Lynch T, Uitti RJ, Wszolek ZK, Kapatos G, Farrer MJ. GCH1 in darly-onset Parkinson's disease. Mov Disord. 2009 Oct 30; 24(14):2070-5.
Cobb SA, Wider C, Ross OA, Mata IF, Adler CH, Rajput A, Rajput AH, Wu RM, Hauser R, Josephs KA, Carr J, Gwinn K, Heckman MG, Aasly JO, Lynch T, Uitti RJ, Wszolek ZK, Kapatos G, Farrer MJ. GCH1 in early-onset Parkinson's disease. Mov Disord. 2009 Oct 30; 24 (14):2070-5
View PubMed
Adler CH. Perioperative use of botulinum toxins. Toxicon. 2009 Oct; 54(5):654-7. Epub 2008 Dec 03.
View PubMed
Driver-Dunckley E, Connor D, Hentz J, Sabbagh M, Silverberg N, Hernandez J, Vedders L, Evidente VG, Shill H, Caviness J, Adler C. No evidence for cognitive dysfunction or depression in patients with mild restless legs syndrome. Mov Disord. 2009 Sep 15; 24 (12):1840-2
View PubMed
Weintraub D, Hoops S, Shea JA, Lyons KE, Pahwa R, Driver-Dunckley ED, Adler CH, Potenza MN, Miyasaki J, Siderowf AD, Duda JE, Hurtig HI, Colcher A, Horn SS, Stern MB, Voon V. Validation of the questionnaire for impulsive-compulsive disorders in Parkinson's disease. Mov Disord. 2009 Jul 30; 24: (10)1461-7.
View PubMed
Sabbagh MN, Adler CH, Lahti TJ, Connor DJ, Vedders L, Peterson LK, Caviness JN, Shill HA, Sue LI, Ziabreva I, Perry E, Ballard CG, Aarsland D, Walker DG, Beach TG. Parkinson disease with dementia: comparing patients with and without Alzheimer pathology. Alzheimer Dis Assoc Disord. 2009 Jul-Sep; 23(3):295-7.
View PubMed
Sabbagh MN, Sandhu SS, Farlow MR, Vedders L, Shill HA, Caviness JN, Connor DJ, Sue L, Adler CH, Beach TG. Correlation of clinical features with argyrophilic grains at autopsy. Alzheimer Dis Assoc Disord. 2009 Jul-Sep; 23(3):229-33.
View PubMed
Almaraz AC, Driver-Dunckley ED, Woodruff BK, Wellik KE, Caselli RJ, Demaerschalk BM, Adler CH, Caviness JN, Wingerchuk DM. Efficacy of rivastigmine for cognitive symptoms in Parkinson disease with dementia. Neurologist. 2009 Jul; 15(4):234-7.
View PubMed
Vilarino-Guell C, Wider C, Soto-Ortolaza AI, Cobb SA, Kachergus JM, Keeling BH, Dachsel JC, Hulihan MM, Dickson DW, Wszolek ZK, Uitti RJ, Graff-Radford NR, Boeve BF, Josephs KA, Miller B, Boylan KB, Gwinn K, Adler CH, Aasly JO, Hentati F, Destee A, Krygowska-Wajs A, Chartier-Harlin MC, Ross OA, Rademakers R, Farrer MJ. Characterization of DCTN1 genetic variability in neurodegeneration. Neurology. 2009 Jun 9; 72 (23):2024-8
View PubMed
Beach TG, Adler CH, Lue L, Sue LI, Bachalakuri J, Henry-Watson J, Sasse J, Boyer S, Shirohi S, Brooks R, Eschbacher J, White CL III, Akiyama H, Caviness J, Shill HA, Connor DJ, Sabbagh MN, Walker DG. Unified staging system for Lewy body disorders: Correlation with nigrostriatal degeneration, cognitive impairment and motor dysfunction. Acta Neuropathol (Berl). 2009 Jun; 117(6):613-34.
Beach TG, White CL III, Hladik CL, Sabbagh MN, Connor DJ, Shill HA, Sue LI, Sasse J, Bachalakuri J, Henry-Watson J, Akiyama H, Adler CH. Olfactory bulb alpha -synucleinopathy has high specificity and sensitivity for Lewy body disorders. Acta Neuropathol (Berl). 2009 Feb; 117: (2)169-74.
Lyons MK, Adler CH, Bansberg SF, Evidente VGH. Spasmodic dysphonia may respond to bilateral thalamic deep brain stimulation. Afr J of Neurol Sci. 2009; 28(1):10-811.
Alvarez MV, Driver-Dunckley EE, Caviness JN, Adler CH, Evidente VG. Case series of painful legs and moving toes: clinical and electrophysiologic observations. Mov Disord. 2008 Oct 30; 23(14):2062-6.
View PubMed
Sparks DL, Ziolkowski C, Connor D, Beach T, Adler C, Sabbagh M. Copper and cognition in Alzheimer's disease and Parkinson's disease. Cell Biology & Toxicology. 2008 Oct; 24(5):426-30.
Ludlow CL, Adler CH, Berke GS, Bielamowicz SA, Blitzer A, Bressman SB, Hallett M, Jinnah HA, Juergens U, Martin SB, Perlmutter JS, Sapienza C, Singleton A, Tanner CM, Woodson GE. Research priorities in spasmodic dysphonia. Otolaryngol Head Neck Surg. 2008 Oct; 139(4):495-505.
View PubMed
Beach TG, White CL, Hamilton RL, Duda JE, Iwatsubo T, Dickson DW, Leverenz JB, Roncaroli F, Buttini M, Hladik CL, Sue LI, Noorigian JV, Adler CH. Evaluation of alpha-synuclein immunohistochemical methods used by invited experts. Acta Neuropathol. 2008 Sep; 116(3):277-88. Epub 2008 Jul 15.
View PubMed
Stamper C, Siegel A, Liang WS, Pearson JV, Stephan DA, Shill H, Connor D, Caviness JN, Sabbagh M, Beach TG, Adler CH, Dunckley T. Neuronal gene expression correlates of Parkinson's disease with dementia. Mov Disord. 2008 Aug 15; 23(11):1588-95.
View PubMed
Ross OA, Braithwaite AT, Skipper LM, Kachergus J, Hulihan MM, Middleton FA, Nishioka K, Fuchs J, Gasser T, Maraganore DM, Adler CH, Larvor L, Chartier-Harlin MC, Nilsson C, Langston JW, Gwinn K, Hattori N, Farrer MJ. Genomic investigation of alpha-synuclein multiplication and parkinsonism. Ann Neurol. 2008 Jun; 63 (6):743-50
View PubMed
Goetz CG, Wuu J, McDermott MP, Adler CH, Fahn S, Freed CR, Hauser RA, Olanow WC, Shoulson I, Tandon PK, Parkinson Study Group, Leurgans S. Placebo response in Parkinson's disease: comparisons among 11 trials covering medical and surgical interventions. Mov Disord. 2008 Apr 15; 23(5):690-9.
View PubMed
Shill HA, Adler CH, Sabbagh MN, Connor DJ, Caviness JN, Hentz JG, Beach TG. Pathologic findings in prospectively ascertained essential tremor subjects. Neurology. 2008 Apr 15; 70(16 Pt 2):1452-5.
View PubMed
Beach TG, Adler CH, Sue LI, Peirce JB, Bachalakuri J, Dalsing-Hernandez JE, Lue LF, Caviness JN, Connor DJ, Sabbagh MN, Walker DG. Reduced striatal tyrosine hydroxylase in incidental Lewy body disease. Acta Neuropathol. 2008 Apr; 115(4):445-51. Epub 2007 Nov 06.
View PubMed
McKinnon JH, Demaerschalk BM, Caviness JN, Wellik KE, Adler CH, Wingerchuk DM. Sniffing out Parkinson disease: can olfactory testing differentiate parkinsonian disorders? Neurologist. 2007 Nov; 13(6):382-5.
View PubMed
Beach TG, Sue LI, Walker DG, Lue LF, Connor DJ, Caviness JN, Sabbagh MN, Adler CH. Marked microglial reaction in normal aging human substantia nigra: correlation with extraneuronal neuromelanin pigment deposits. Acta Neuropathol (Berl). 2007 Oct; 114: (4)419-24.
View PubMed
Driver-Dunckley ED, Noble BN, Hentz JG, Evidente VG, Caviness JN, Parish J, Krahn L, Adler CH. Gambling and increased sexual desire with dopaminergic medications in restless legs syndrome. Clin Neuropharmacol. 2007 Sep-Oct; 30 (5):249-55
View PubMed
Caviness JN, Hentz JG, Evidente VG, Driver-Dunckley E, Samanta J, Mahant P, Connor DJ, Sabbagh MN, Shill HA, Adler CH. Both early and late cognitive dysfunction affects the electroencephalogram in Parkinson's disease. Parkinsonism Relat Disord. 2007 Aug; 13: (6)348-54.
View PubMed
Trosch RM, Adler CH, Pappert EJ. Botulinum toxin type B (Myobloc(R)) in subjects with hemifacial spasm: Results from an open-label, dose-escalation safety study. Mov Disord. 2007 Jul 15; 22(9):1258-64.
View PubMed
Caviness JN, Driver-Dunckley E, Connor DJ, Sabbagh MN, Hentz JG, Noble B, Evidente VG, Shill HA, Adler CH. Defining mild cognitive impairment in Parkinson's disease. Mov Disord. 2007 Jul 15; 22 (9):1272-7
View PubMed
Snyder CH, Adler CH. The patient with Parkinson's disease: part I-treating the motor symptoms; part II-treating the nonmotor symptoms. J Am Acad Nurse Pract. 2007 Apr; 19(4):179-97.
View PubMed
Melquist S, Craig DW, Huentelman MJ, Crook R, Pearson JV, Baker M, Zismann VL, Gass J, Adamson J, Szelinger S, Corneveaux J, Cannon A, Coon KD, Lincoln S, Adler C, Tuite P, Calne DB, Bigio EH, Uitti RJ, Wszolek ZK, Golbe LI, Caselli RJ, Graff-Radford N, Litvan I, Farrer MJ, Dickson DW, Hutton M, Stephan DA. Identification of a novel risk locus for progressive supranuclear palsy by a pooled genomewide scan of 500,288 single-nucleotide polymorphisms. Am J Hum Genet. 2007 Apr; 80 (4):769-78 Epub 2007 Mar 08
View PubMed
Toft M, Mata IF, Ross OA, Kachergus J, Hulihan MM, Haugarvoll K, Stone JT, Blazquez M, Gibson JM, Aasly JO, White LR, Lynch T, Adler CH, Gwinn-Hardy K, Farrer MJ. Pathogenicity of the Lrrk2 R1514Q substitution in Parkinson's disease. Mov Disord. 2007 Feb 15; 22 (3):389-92
View PubMed
NINDS NET-PD Investigators. A randomized clinical trial of coenzyme Q10 and GPI-1485 in early Parkinson disease. Neurology. 2007 Jan 2; 68 (1):20-8
View PubMed
Langbehn DR, Paulsen JS, Hedges P, McCusker E, Pearce S, Trent R, Abwender D, Como P, Gardiner I, Hickey C, Kayson E, Kieburtz K, Marshall F, Pearson N, Shoulson I, Zimmerman C, Louis E, Marder K, Moskowitz C, Polanco C, Taylor S, Zubin N, Brown C, Burke-Holder J, Guttman M, Russell S, Stewart D, Thomson J, Sax DS, Saint-Hilaire M, Gray J, Hunter C, Mercado N, Siemers E, Wojcieszek J, Dawson T, Leritz E, Rosenblatt A, Sherr M, Young C, Ashizawa T, Beach J, Jankovic J, Jaglin J, Shannon K, Lundin A, Francis K, Lane K, Auchus A, Greenamyre JT, Hersch S, Jones R, Olson D, Cha, J-HJ, Cudkowicz M, Koroshetz W, Rudolf G, Sexton P, Young AB, Albin R, Wernette K, Higgins DS, Reider C, Hunt V, Walker F, Hauser R, Sanchez-Ramos J, Walker A, Nance M, Cleary S, Rohs G, Suchowersky O, Duncan K, Seeberger L, Corey-Bloom J, Swenson M, Swerdlow N, Paulson H, Rodnitzky R, Vining L, Martin W, Wieler M, Facca A, Rey G, Weiner W, Adler C, Caviness J, Lied C, Newman S, Feigin A, Mazurkiewicz J, Caplan K, Cellar J, Marek K, Hayden M, Raymond L, Dure LS, Lane J, Brown D, Factor S, Molho E, Harrison M, Manning C, Rost-Ruffner E, Adams J, Cummings R, Wheelock V, Dubinsky R, Gray C, Catherine Bachoud-Levi A, Meierkord H, Friedman J, Lannon M, Lawrence J, Rubin A, Schwarz R, Brocht A, Claude K, Goldstein J, McDermott M, Oakes D. Predictors of diagnosis in Huntington disease. Neurology. 2007; 68(20):1710-7.
Sabbagh MN, Lahti T, Connor DJ, Caviness JN, Shill H, Vedders L, Mahant P, Samanta J, Burns RS, Evidente VG, Driver-Dunckley E, Reisberg B, Bircea S, Adler CH. Functional ability correlates with cognitive impairment in Parkinson's disease and Alzheimer's disease. Dement Geriatr Cogn Disord. 2007; 24: (5)327-34.
View PubMed
Jankovic J, Hunter C, Dolimbek BZ, Dolimbek GS, Adler CH, Brashear A, Comella CL, Gordon M, Riley DE, Sethi K, Singer C, Stacy M, Tarsy D, Atassi MZ. Clinico-immunologic aspects of botulinum toxin type B treatment of cervical dystonia. Neurology. 2006 Dec 26; 67(12):2233-5.
View PubMed
Driver-Dunckley E, Evidente VG, Adler CH, Hillman R, Hernandez J, Fletcher G, Lyons MK. Restless legs syndrome in Parkinson's disease patients may improve with subthalamic stimulation. Mov Disord. 2006 Aug; 21 (8):1287-9
View PubMed
Biglan KM, Schwid S, Eberly S, Blindauer K, Fahn S, Goren T, Kieburtz K, Oakes D, Plumb S, Siderowf A, Stern M, Shoulson I. Rasagiline improves quality of life in patients with early Parkinson's disease. Mov Disord. 2006 May; 21(5):616-23.
View PubMed
Caviness JN, Liss JM, Adler C, Evidente V. Analysis of high-frequency electroencephalographic-electromyographic coherence elicited by speech and oral nonspeech tasks in Parkinson's disease. J Speech Lang Hear Res. 2006 Apr; 49(2):424-38.
View PubMed
Caviness JN, Shill HA, Sabbagh MN, Evidente VG, Hernandez JL, Adler CH. Corticomuscular coherence is increased in the small postural tremor of Parkinson's disease. Mov Disord. 2006 Apr; 21(4):492-9.
View PubMed
NINDS NET-PD Investigators. A randomized, double-blind, futility clinical trial of creatine and minocycline in early Parkinson disease. Neurology. 2006 Mar 14; 66 (5):664-71 Epub 2006 Feb 15
View PubMed
Blindauer K, Shoulson I, Oakes D, Kieburtz K, Schwid S, Fahn S, Stern M, Goetz C, Nutt J, Goren S, Sayag N, Scolnik M, Levy R, Eyal E, Salzman P, Pagano M. A randomized controlled trial of etilevodopa in patients with Parkinson disease who have motor fluctuations. Arch Neurol. 2006 Feb; 63(2):210-6.
View PubMed
Mata IF, Bodkin CL, Adler CH, Lin SC, Uitti RJ, Farrer MJ, Wszolek ZK. Genetics of restless legs syndrome. Parkinsonism Relat Disord. 2006 Jan; 12(1):1-7.
View PubMed
Sparks DL, Petanceska S, Sabbagh M, Connor D, Soares H, Adler C, Lopez J, Ziolkowski C, Lochhead J, Browne P. Cholesterol, copper and A beta in controls, MCI, AD and the AD cholesterol-lowering treatment trial (ADCLT). Current Alzheimer Research. 2005 Dec; 2(5):527-39.
Comella CL, Jankovic J, Shannon KM, Tsui J, Swenson M, Leurgans S, Fan W. Comparison of botulinum toxin serotypes A and B for the treatment of cervical dystonia. Neurology. 2005 Nov 8; 65(9):1423-9.
View PubMed
Thorpy MJ, Adler CH. Parkinson's disease and sleep. Neurol Clin. 2005 Nov; 23(4):1187-208.
View PubMed
Sabbagh MN, Silverberg N, Bircea S, Majeed B, Samant S, Caviness JN, Reisberg B, Adler CH. Is the functional decline of Parkinson's disease similar to the functional decline of Alzheimer's disease? Parkinsonism Relat Disord. 2005 Aug; 11(5):311-5.
View PubMed
Adler CH, Thorpy MJ. Sleep issues in Parkinson's disease. Neurology. 2005 Jun 28; 64 (12 Suppl 3):S12-20
View PubMed
Wunderlich GR, Evans KR, Sills T, Pollentier S, Reess J, Allen RP, Hening W, Walter AS. An item response analysis of the international restless legs syndrome study group rating scale for restless legs syndrome. Sleep med. 2005 Mar; 6(2):131-9.
Toft M, Aasly J, Bisceglio G, Adler CH, Uitti RJ, Krygowska-Wajs A, Lynch T, Wszolek ZK, Farrer MJ. Parkinsonism, FXTAS, and FMR1 premutations. Mov Disord. 2005 Feb; 20(2):230-3.
View PubMed
Adler CH. Nonmotor complications in Parkinson's disease. Mov Disord. 2005; 20 Suppl 11:S23-9
View PubMed
Fahn S, Oakes D, Shoulson I, Kieburtz K, Rudolph A, Lang A, Olanow CW, Tanner C, Marek K, Parkinson Study Group. Levodopa and the progression of Parkinson's disease. N Engl J Med. 2004 Dec 9; 351 (24):2498-508
View PubMed
Adler CH, Bansberg SF, Hentz JG, Ramig LO, Buder EH, Witt K, Edwards BW, Krein-Jones K, Caviness JN. Botulinum toxin type A for treating voice tremor. Arch Neurol. 2004 Sep; 61(9):1416-20.
View PubMed
Adler CH, Bansberg SF, Krein-Jones K, Hentz JG. Safety and efficacy of botulinum toxin type B (Myobloc) in adductor spasmodic dysphonia. Mov Disord. 2004 Sep; 19(9):1075-9.
View PubMed
Pittock SJ, Parrett T, Adler CH, Parisi JE, Dickson DW, Ahlskog JE. Neuropathology of primary restless leg syndrome: absence of specific tau- and alpha-synuclein pathology. Mov Disord. 2004 Jun; 19(6):695-9.
View PubMed
Adler CH, Hauser RA, Sethi K, Caviness JN, Marlor L, Anderson WM, Hentz JG. Ropinirole for restless legs syndrome: a placebo-controlled crossover trial. Neurology. 2004 Apr 27; 62 (8):1405-7
View PubMed
Van Gemmert AWA, Adler CH, Stelmach GE. Parkinson's disease patients undershoot target size in handwriting and similar tasks. Journal of Neurology, Neurosurgery & Psychiatry. 2003 Nov; 74(11):1502-8.
View PubMed
Singleton AB, Farrer M, Johnson J, Singleton A, Hague S, Kachergus J, Hulihan M, Peuralinna T, Dutra A, Nussbaum R, Lincoln S, Crawley A, Hanson M, Maraganore D, Adler C, Cookson MR, Muenter M, Baptista M, Miller D, Blancato J, Hardy J, Gwinn-Hardy K. alpha-Synuclein locus triplication causes Parkinson's disease. Science. 2003 Oct 31; 302(5646):841.
View PubMed
Caviness JN, Adler CH, Sabbagh MN, Connor DJ, Hernandez JL, Lagerlund TD. Abnormal corticomuscular coherence is associated with the small amplitude cortical myoclonus in Parkinson's disease. Mov Disord. 2003 Oct; 18(10):1157-62.
View PubMed
Evidente VG, Caviness JN, Adler CH. Case studies in movement disorders. Semin Neurol. 2003 Sep; 23(3):277-84.
View PubMed
Romero DH, Van Gemmert AWA, Adler CH, Bekkering H, Stelmach GE. Altered aiming movements in Parkinson's disease patients and elderly adults as a function of delays in movement onset. Exp Brain Res. 2003 Jul; 151(2):249-61.
View PubMed
Beach TG, Sue L, Scott S, Layne K, Newell A, Walker D, Baker M, Sahara N, Yen SH, Hutton M, Caselli R, Adler C, Connor D, Sabbagh M. Hippocampal sclerosis dementia with tauopathy. Brain Pathol. 2003 Jul; 13(3):263-78.
View PubMed
Romero DH, Van Gemmert AWA, Adler CH, Bekkering H, Stelmach GE. Time delays prior to movement alter the drawing kinematics of elderly adults. Human Movement Science. 2003 Apr; 22(2):207-20.
View PubMed
Adler CH, Caviness JN, Hentz JG, Lind M, Tiede J. Randomized trial of modafinil for treating subjective daytime sleepiness in patients with Parkinson's disease. Mov Disord. 2003 Mar; 18 (3):287-293
View PubMed
Comella CL, Leurgans S, Wuu J, Stebbins GT, Chmura T, The Dystonia Study Group. Rating scales for dystonia: A multicenter assessment. Mov Disorders. 2003; 18:303-12.
Allen RP, Picchietti D, Hening WA, Trenkwalder C, Walters AS, Montlaisir J, the participants in the RLS Diagnosis Epidemiology workshop at the NIH, in collaboration with members of the International RLS Study Group. Restless legs syndrome: diagnostic criteria, special considerations, and epidemiology. A report from the restless legs syndrome diagnosis and epidemiology workshop at the National Institutes of Health Sleep Medicine. 2003; 4:101-19.
Adler CH, Thorpy MJ. Awake and Involved: Addressing excessive daytime sleepiness in patients with Parkinson's disease, Overview of Parkinson's disease (Review Article). The Treatment Reporter Neurology. 2003(Part 1).
Thorpy MJ, Adler CH. Awake and Involved: Addressing excessive daytime sleepiness in patients with Parkinson's disease, Sleep issues in Parkinson's disease (Review Article). The Treatment Reporter Neurology. 2003; Part 2.
Smith AM, Adler CH, Crews D, Wharen RE, Laskowski ER, Barnes K, Valone Bell C, Pelz D, Brennan RD, Smith J, Sorenson MC, Kaufman KR. The 'yips' in golf: a continuum between a focal dystonia and choking. Sports Med. 2003; 33 (1):13-31
View PubMed
Contreras-Vidal JL, Teulings HL, Stelmach GE, Adler CH. Adaptation to changes in vertical display gain during handwriting in Parkinson's disease patients, elderly and young controls. Parkinsonism & Related Disorders. 2002 Dec; 9(2):77-84.
View PubMed
Adler CH, Hentz JG, Joyce JN, Beach T, Caviness JN. Motor impairment in normal aging, clinically possible Parkinson's disease, and clinically probable Parkinson's disease: longitudinal evaluation of a cohort of prospective brain donors. Parkinsonism Relat Disord. 2002 Dec; 9 (2):103-10
View PubMed
Liss JM, Spitzer SM, Caviness JN, Adler C. The effects of familiarization on intelligibility and lexical segmentation in hypokinetic and ataxic dysarthria. J Acoust Soc Am. 2002 Dec; 112(6):3022-30.
View PubMed
Parkinson Study Group. A controlled trial of rasagiline in early Parkinson disease: the TEMPO Study. Arch Neurol. 2002 Dec; 59 (12):1937-43
View PubMed
Joyce JN, Ryoo HL, Beach TB, Caviness JN, Stacy M, Gurevich EV, Reiser M, Adler CH. Loss of response to levodopa in Parkinson's disease and co-occurrence with dementia: role of D-3 and not D-2 receptors. Brain Res. 2002 Nov 15; 955(1-2):138-52.
View PubMed
Korczyn AD, Thalamas C, Adler CH. Dosing with ropinirole in a clinical setting. Acta Neurol Scand. 2002 Oct; 106(4):200-4.
View PubMed
Caviness JN, Adler CH, Beach TG, Wetjen KL, Caselli RJ. Small-amplitude cortical myoclonus in Parkinson's disease: Physiology and clinical observations. Mov Disord. 2002 Jul; 17(4):657-62.
View PubMed
Kompoliti K, Adler CH, Raman R, Pincus JH, Leibowitz MT, Ferry JJ, Blasucci L, Caviness JN, Leurgans S, Chase WM, Yones LC, Tan E, Carvey P, Goetz CG. Gender and pramipexole effects on levodopa pharmacokinetics and pharmacodynamics. Neurology. 2002 May 14; 58(9):1418-22.
View PubMed
Vernino S, Tuite P, Adler CH, Meschia JF, Boeve BF, Boasberg P, Parisi JE, Lennon VA. Paraneoplastic chorea associated with CRMP-5 neuronal antibody and lung carcinoma. Ann Neurol. 2002 May; 51(5):625-30.
View PubMed
Teulings HL, Contreras-Vidal JL, Stelmach GE, Adler CH. Adaptation of handwriting size under distorted visual feedback in patients with Parkinson's disease and elderly and young controls. Journal of Neurology, Neurosurgery & Psychiatry.. 2002 Mar; 72: (3)315-24.
View PubMed
Adler CH. Relevance of motor complications in Parkinson's disease. Neurology. 2002 Feb 26; 58 (4 Suppl 1):S51-6
View PubMed
Adler CH, Factor SA, Brin M, Sethi KD. Secondary nonresponsiveness to botulinum toxin type A in patients with oromandibular dystonia. Mov Disord. 2002 Jan; 17 (1):158-61
View PubMed
Caviness JN, Smith BE, Clarke Stevens J, Stevens JC, Adler CH, Caselli RJ, Hentz JG, Manfred MS, Muenter D. Motor unit number estimates in idiopathic Parkinson's disease. Parkinsonism Relat Disord. 2002 Jan; 8 (3):161-4
View PubMed
Adler CH. Diagnosing and treating restless legs syndrome. Women's Health Orthopedic Edition. 2002; 5:54-8.
Caviness JN, Adler CH, Beach TG, Wetjen KL, Caselli RJ. Myoclonus in Lewy body disorders. Adv Neurol. 2002; 89:23-30.
View PubMed
Adler CH, Joyce JN. Collaboration Amongst Arizona Parkinson's Disease Research Centers-Parkinson's Disease Center Without Walls (Review Article). AZ Parkinson's Disease Report. 2002.
Adler CH. Managing movement disorders with botulinum toxins: An effective approach for dystonia, tics, tremor, and hemifacial spasm (Review Article). Women's Health in Primary Care. 2002; 5:707-19.
Evidente VG, Evidente VG, Caviness JN, Adler CH, Gwinn-Hardy KA, Pratley RE. Serum leptin concentrations and satiety in Parkinson's disease patients with and without weight loss. Mov Disord. 2001 Sep; 16 (5):924-7
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Joyce JN, Ryoo H, Gurevich EV, Adler C, Beach T. Ventral striatal D(3) receptors and Parkinson's Disease. Parkinsonism Relat Disord. 2001 Jul; 7(3):225-230.
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Brin MF, Lyons KE, Doucette J, Adler CH, Caviness JN, Comella CL, Dubinsky RM, Friedman JH, Manyam BV, Matsumoto JY, Pullman SL, Rajput AH, Sethi KD, Tanner C, Koller WC. A randomized, double masked, controlled trial of botulinum toxin type A in essential hand tremor. Neurology. 2001 Jun 12; 56(11):1523-8.
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Alberts JL, Adler CH, Saling M, Stelmach GE. Prehension patterns in restless legs syndrome patients. Parkinsonism & Related Disorders. 2001 Apr; 7(2):143-148.
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Shoulson I, Penney J, McDermott M, Schwid S, Kayson E, Chase T, Fahn S, Greenamyre JT, Lang A, Siderowf A, Pearson N, Harrison M, Rost E, Colcher A, Lloyd M, Matthews M, Pahwa R, McGuire D, Lew MF, Schuman S, Marek K, Broshjeit S, Factor S, Brown D, Feigin A, Mazurkiewicz J, Ford B, Jennings D, Dilllon S, Comella C, Blasucci L, Janko K, Shulman L, Wiener W, Bateman-Rodriguez D, Carrion A, Suchowersky O, Lafontaine AL, Pantella C, Siemers E, Belden J, Davies R, Lannon M, Grimes D, Gray P, Martin W, Kennedy L, Adler C, Newman S, Hammerstad J, Stone C, Lewitt P, Bardram K, Mistura K, Miyasaki J, Johnston L, Cha JH, Tennis M, Panniset M, Hall J, Tetrud J, Friedlander J, Hauser R, Gauger L, Rodnitzky R, Deleo A, Dobson J, Seeberger L, Dingmann C, Tarsy D, Ryan P, Elmer L, Ruzicka D, Stacy M, Brewer M, Locke B, Baker D, Casaceli C, Day D, Florack M, Hodgeman K, Laroia N, Nobel R, Orme C, Rexo L, Rothenburgh K, Sulimowicz K, Watts A, Wratni E, Tariot P, Cox C, Leventhal C, Alderfer V, Craun AM, Frey J, McCree L, McDermott J, Cooper J, Holdich T, Read B, Parkinson Study Group. A randomized, controlled trial of remacemide for motor fluctuations in Parkinson's disease. Neurology. 2001 Feb 27; 56(4):455-62.
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Caviness JN, Smith BE, Stevens JC, Adler CH, Caselli RJ, Hentz JG, Muenter MD. Motor Unit Number Estimates in Idiopathic Parkinson's Disease. Parkinsonism and Related Disorders. 2001; 8:161-4.
Adler CH. Ten commonly asked questions about initiating treatment for Parkinson's disease (Review Article). The Neurologist. 2001; 7(3):188-92.
Adler CH. Diagnosing and treating restless legs syndrome (Review Article). Women's Health In Primary Care. 2001; 4:224-8.
Adler CH. Diagnosing and treating restless legs syndrome (Review Article). Women's Health Gynecology Edition. 2001; 1:371-8.
Pennachio DL, Consultants. Parkinson's disease: Progress along the continuum of care (Review Article). Patient Care. 2000 Dec.
Adler CH. Questions and answers about clinical trials (Review Article). Nightwalkers: Restless Legs Syndrome Newsletter. 2000 Nov.
Alberts JL, Saling M, Adler CH, Stelmach GE. Disruptions in the reach-to-grasp actions of Parkinson's patients. Exp Brain Res. 2000 Oct; 134(3):353-62.
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Adler CH. Strategies for controlling dystonia. Overview of therapies that may alleviate symptoms. Postgrad Med. 2000 Oct; 108 (5):151-2, 155-6, 159-60
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Cooper C, Evidente VG, Hentz JG, Evidente VG, Adler CH, Caviness JN, Gwinn-Hardy K. The effect of temperature on hand function in patients with tremor. J Hand Ther. 2000 Oct-Dec; 13 (4):276-88
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Liss JM, Spitzer SM, Caviness JN, Adler C, Edwards BW. Lexical boundary error analysis in hypokinetic and ataxic dysarthria. J Acoust Soc Am. 2000 Jun; 107(6):3415-24.
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Gwinn-Hardy KA, Adler CH, Weaver AL, Fish NM, Newman SJ. Effect of hormone variations and other factors on symptom severity in women with dystonia. Mayo Clin Proc. 2000 Mar; 75(3):235-40.
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Evidente VG, Evidente VG, Adler CH, Caviness JN, Hentz JG, Gwinn-Hardy K. Amantadine is beneficial in restless legs syndrome. Mov Disord. 2000 Mar; 15 (2):324-7
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Caviness JN, Smith BE, Stevens JC, Adler CH, Caselli RJ, Reiners CA, Hentz JG, Muenter MD. Motor unit changes in sporadic idiopathic Parkinson's disease. Mov Disord. 2000 Mar; 15 (2):238-43
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Hauser RA, Friedlander J, Zesiewicz TA, Adler CH, Seeberger LC, O'Brien CF, Molho ES, Factor SA. A home diary to assess functional status in patients with Parkinson's disease with motor fluctuations and dyskinesia. Clin Neuropharmacol. 2000 Mar-Apr; 23(2):75-81.
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Gwinn-Hardy KA, Crook R, Lincoln S, Adler CH, Caviness JN, Hardy J, Farrer M. A kindred with Parkinson's disease not showing genetic linkage to established loci. Neurology. 2000 Jan 25; 54(2):504-7.
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Adler CH, Kumar R. Pharmacological and surgical options for the treatment of cervical dystonia. Neurology. 2000; 55(12 Suppl 5):S9-14.
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Caviness JN, Gwinn-Hardy K, Adler CH, Muenter MD. Electrophysiological observations in hereditary parkinsonism-dementia with Lewy body pathology. Mov Disord. 2000 Jan; 15 (1):140-5
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Spitzer SM, Liss JM, Caviness JN, Adler C. The effects of familiarization on listener perception of hypokinetic and ataxic dysarthric speech. Journal of Medical Speech-Language Pathology. 2000; 8:285-93.
Joyce JN, Adler CH. Research for new treatment of Parkinson's disease (Review Article). Southwest Parkinson Report. 2000 Spr/Sum.
Adler CH. Review of New-Onset Tic Disorders in Adults (Review Article). Journal Watch Neurology. 2000; 2:73-4.
Brin MF, Lew MF, Adler CH, Comella CL, Factor SA, Jankovic J, O'Brien C, Murray JJ, Wallace JD, Willmer-Hulme A, Koller M. Safety and efficacy of NeuroBloc (botulinum toxin type B) in type A-resistant cervical dystonia. Neurology. 1999 Oct 22; 53(7):1431-8.
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Weiss PH, Stelmach GE, Chaiken A, Adler CH. Use of advance information for complex movements in Parkinson's disease. Parkinsonism & Related Disorders. 1999 Apr-May; 5(1-2):19-25.
Evidente VG, Adler CH. How to help patients with restless legs syndrome. Discerning the indescribable and relaxing the restless. Postgrad Med. 1999 Mar; 105: (3)59-61, 65-6, 73-4.
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Adler CH. Differential diagnosis of Parkinson's disease. Med Clin North Am. 1999 Mar; 83 (2):349-67
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Farrer M, Gwinn-Hardy K, Muenter M, DeVrieze FW, Crook R, Perez-Tur J, Lincoln S, Maraganore D, Adler C, Newman S, MacElwee K, McCarthy P, Miller C, Waters C, Hardy J. A chromosome 4p haplotype segregating with Parkinson's disease and postural tremor. Hum Mol Genet. 1999 Jan; 8(1):81-5.
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Evidente VG, Evidente VG, Adler CH, Caviness JN, Gwinn-Hardy K. A pilot study on the motor effects of rimantadine in Parkinson's disease. Clin Neuropharmacol. 1999 Jan-Feb; 22 (1):30-2
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Liss JM, Spitzer S, Caviness JN, Adler C, Edwards B. Syllabic strength and lexical boundary decisions in the perception of hypokinetic dysarthric speech. J Acoust Soc Am. 1998 Oct; 104(4):2457-66.
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Adler CH. Botulinum toxin: Overview and use in tremor disorders (Review Article). International Tremor Foundation Newsletter. 1998 Oct.
Sethi KD, Obrien CF, Hammerstad JP, Adler CH, Davis TL, Taylor RL, Sanchezramos J, Bertoni JM, Hauser RA. Ropinirole for the treatment of early Parkinson-disease - a 12-month experience. Arch Neurol. 1998 Sep; 55(9):1211-1216.
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Evidente VG, Adler CH, Caviness JN, Gwinn KA. Effective treatment of orthostatic tremor with gabapentin. Mov Disord. 1998 Sep; 13 (5):829-31
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Adler CH, Singer C, O'Brien C, Hauser RA, Lew MF, Marek KL, Dorflinger E, Pedder S, Deptula D, Yoo K. Randomized, placebo-controlled study of tolcapone in patients with fluctuating Parkinson disease treated with levodopa-carbidopa. Tolcapone Fluctuator Study Group III. Arch Neurol. 1998 Aug; 55 (8):1089-95
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Kurth MC, Adler CH. COMT inhibition: a new treatment strategy for Parkinson's disease. Neurology. 1998 May; 50(5 Suppl 5):S3-14.
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Caviness JN, Adler CH, Newman S, Caselli RJ, Muenter MD. Cortical myoclonus in levodopa-responsive parkinsonism. Mov Disord. 1998 May; 13(3):540-4.
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Johnstone SJ, Adler CH. Headache and facial pain responsive to botulinum toxin: an unusual presentation of blepharospasm. Headache. 1998 May; 38(5):366-8.
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Adler CH, Gwinn KA, Newman S. Olfactory function in restless legs syndrome. Mov Disord. 1998 May; 13(3):563-5.
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Evidente VG, Adler CH, Giannini C, Conley CR, Parisi JE, Fletcher GP. Erdheim-Chester disease with extensive intraaxial brain stem lesions presenting as a progressive cerebellar syndrome. Mov Disord. 1998 May; 13(3):576-81.
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Shannon KM, Penn RD, Kroin JS, Adler CH, Janko KA, York M, Cox SJ. Stereotactic pallidotomy for the treatment of Parkinson's disease. Efficacy and adverse effects at 6 months in 26 patients. Neurology. 1998 Feb; 50(2):434-8.
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Adler CH. COMT inhibitors: novel treatments for Parkinson's disease. CNS Spectrums. 1998; 3(2):53-56.
Evidente VG, Adler CH. Hemifacial spasm and other craniofacial movement disorders. Mayo Clin Proc. 1998 Jan; 73(1):67-71.
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Johnstone S, Adler CH. Headache and facial pain: Response to botulinum toxin (Review Article). Benign Essential Blepharospasm Newsletter. 1998; 17(5):5.
Tresilian JR, Stelmach GE, Adler CH. Stability of reach-to-grasp movement patterns in Parkinson's disease. Brain. 1997 Nov; 120(Pt 11):2093-111.
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Uitti RJ, Wharen RE Jr, Turk MF, Lucas JA, Finton MJ, Graff-Radford NR, Boylan KB, Goerss SJ, Kall BA, Adler CH, Caviness JN, Atkinson EJ. Unilateral pallidotomy for Parkinson's disease: comparison of outcome in younger versus elderly patients. Neurology. 1997 Oct; 49 (4):1072-7
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Adler CH, Sethi KD, Hauser RA, Davis TL, Hammerstad JP, Bertoni J, Taylor RL, Sanchez-Ramos J, O'Brien CF. Ropinirole for the treatment of early Parkinson's disease. The Ropinirole Study Group. Neurology. 1997 Aug; 49 (2):393-9
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Teulings HL, Contreras-Vidal JL, Stelmach GE, Adler CH. Parkinsonism reduces coordination of fingers, wrist, and arm in fine motor control. Exp Neurol. 1997 Jul; 146(1):159-70.
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O'Neill MA, Gwinn KA, Adler CH. Biofeedback for writer's cramp. Am J Occup Ther. 1997 Jul-Aug; 51 (7):605-7
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Evidente VGH, Adler CH. Pharmacologic options for managing Parkinson's-disease. Hosp Formul. 1997 Jun; 32(6):594-610.
Adler CH, Caviness JN. Dystonia secondary to electrical injury: surface electromyographic evaluation and implications for the organicity of the condition. J Neurol Sci. 1997 May 29; 148 (2):187-92
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Adler CH. Treatment of restless legs syndrome with gabapentin. Clin Neuropharmacol. 1997 Apr; 20 (2):148-51
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Kurth MC, Adler CH, Sthilaire M, Singer C, Waters C, Lewitt P, Chernik DA, Dorflinger EE, Yoo K, Lieberman AN, Brewer M, Sainthilaire M, Pery LM, Thomas C, Turpin L, Obrien CF, Seeberger LC, Duncan KL, Caviness JN, Douglas M, Wheeler K, Riley D, Rainey P, Tanner CM, Kelker K, et al. Tolcapone improves motor function and reduces levodopa requirement in patients with Parkinson's disease experiencing motor fluctuations - a multicenter, double blind, randomized, placebo-controlled trial. Neurology. 1997 Jan; 48(1):81-87.
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Evidente V, Adler CH. Current management of Parkinson's disease. Formulary. 1997; 32:594-610.
Adler CH, Joyce J. Parkinson's disease and your brain (Review Article). Arizona Parkinson Report Summer,. 1997;
Lieberman A, Caviness JN, The Pramipexole Study Group. Clinical evaluation of pramipexole in advanced Parkinson's disease: Results of a double-blind, placebo-controled, parallel-group study. Neurology. 1997; 49(162-8).
Weiss P, Stelmach GE, Adler CH, Waterman C. Parkinsonian arm movements as altered by task difficulty. Parkinsonism Relat Disord. 1996 Oct; 2 (4):215-23
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Ahlskog JE, Wright KF, Muenter MD, Adler CH. Adjunctive cabergoline therapy of Parkinson's disease: comparison with placebo and assessment of dose responses and duration of effect. Clin Neuropharmacol. 1996 Jun; 19 (3):202-12
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Hutton JT, Koller WC, Ahlskog JE, Pahwa R, Hurtig HI, Stern MB, Hiner BC, Lieberman A, Pfeiffer RF, Rodnitzky RL, Waters CH, Muenter MD, Adler CH, Morris JL. Multicenter, placebo-controlled trial of cabergoline taken once daily in the treatment of Parkinson's disease. Neurology. 1996 Apr; 46(4):1062-5.
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Adler CH, Zimmerman RS, Lyons MK, Simeone F, Brin MF. Perioperative use of botulinum toxin for movement disorder-induced cervical spine disease. Mov Disord. 1996 Jan; 11(1):79-81.
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Adler CH, Wrabetz LG. Lesch-Nyhan variant: Dystonia, ataxia, near-normal intelligence, and no self-mutilation. Movement Disorders. 1996; 11:583-4.
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Adler CH, Stern MB, Shils J, Stecker MM. Movement analysis in generalized and hemiparkinsonism. J Human Movement Studies. 1995; 29:51-62.
Adler CH. Why? I don't know! (Review Article). NSTA Newsletter 4. 1995; 12: (1)
Pestronk A, Choksi R, Bieser K, Goldstein JM, Adler CH, Caselli RJ, George EB. Treatable gait disorder and polyneuropathy associated with high titer serum IgM binding to antigens that copurify with myelin-associated glycoprotein. Muscle & Nerve. 1994 Nov; 17(11):1293-300.
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Adler CH, Wrabetz L, Brin MF, Hurtig HI. Cerebellar ataxia, dystonia, and tremor within a family: variable phenotypes of a single genetic disorder? Mov Disord. 1994 Mar; 9(2):155-60.
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Stern MB, Doty RL, Dotti M, Corcoran P, Crawford D, McKeown DA, Adler CH, Gollomp S, Hurtig H. Olfactory function in Parkinson's disease subtypes. Neurology. 1994; 44:266-8.
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Bennett KMB, Adler CH, Stelmach GE, Castiello U. A kinematic study of the reach to grasp movement in a patient with hemi-Parkinson disease. Neuropsychologia. 1993; 31:709-716.
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Castiello U, Bennett KMB, Adler CH, Stelmach GE. Perturbation of the grasp component of a prehension movement in a patient with hemi-Parkinson disease. Neuropsychologia. 1993; 31:717-723.
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Bernardi B, Zimmerman RA, Savino PJ, Adler C. Magnetic resonance tomographic angiography in the investigation of hemifacial spasm. Neuroradiology. 1993; 35(8):606-11.
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Adler CH. Mechanism of action of botulinum toxin (Review Article). NSTA Newsletter 4. 1993; 10: (2)
Adler CH, Zimmerman RA, Savino PJ, Bernardi B, Bosley TM, Sergott RC. Hemifacial spasm: evaluation by magnetic resonance imaging and magnetic resonance tomographic angiography. Ann Neurol. 1992 Oct; 32(4):502-6.
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Dodick D, Adler CH. Tourette's syndrome. Current approaches to recognition and management. Postgrad Med. 1992 Oct; 92 (5):299-302, 305-8
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Adler CH, Hurtig HI, Jacobson MP, Brooks ML. CPC: a woman with lung and brain masses. J Neuroimaging. 1992; 2:97-101.
Arai H, Schmidt ML, Lee VMY, Hurtig HI, Greenberg BD, Adler CH, Trojanowski JQ. Epitope analysis of senile plaque components in the hippocampus. Neurology. 1992; 42:1315-1322.
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Adler CH. Dystonia, clinical overview. Clin Semin Mov Disord. 1992; 1:14-16.
Adler CH. Botulinum toxin A therapy in dystonia. Hosp Pract (Off Ed). 1991 Aug 15; 26 (8):35, 38, 41-2
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Adler CH, Galetta SL. Oculo-facial-skeletal myorhythmia in Whipple disease: treatment with ceftriaxone. Ann Intern Med. 1990 Mar 15; 112(6):467-9.
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Adler CH, Stern MB, Brooks ML. Parkinsonism secondary to bilateral striatal fungal abscesses. Mov Disord. 1989; 4(4):333-7.
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Adler CH, Meller E, Goldstein M. Receptor reserve at functional alpha-2 adrenergic autoreceptors in the rat cerebral cortex. J Pharmacol Exp Ther. 1987; 240:508-515.
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Meller E, Helmer-Matyjek E, Bohmaker K, Adler CH, Friedhoff AJ, Goldstein M. Receptor reserve at striatal dopamine autoreceptors: implications for selectivity of dopamine agonists. Eur J Pharmacol. 1986 Apr 16; 123(2):311-4.
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Goldstein M, Kusano N, Adler C, Meller E. Characterization of central neuropeptide Y receptor binding sites and possible interactions with alpha 2-adrenoceptors. Prog Brain Res. 1986; 68:331-5.
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Adler CH, Meller E, Goldstein M. Recovery of alpha 2-adrenoceptor binding and function after irreversible inactivation by N-ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline (EEDQ). Eur J Pharmacol. 1985 Oct 8; 116(1-2):175-8.
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Adler CH, Robin M, Adler MW. Tolerance to morphine-induced mydriasis in the rat pupil. Life Sci. 1981 Jun 1; 28(22):2469-75.
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Adler C, Keren O, Korczyn AD. Tolerance to the Mydriatic effects of morphine in mice. J Neural Transm. 1980; 48(1):43-7.
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Klemfuss H, Tallarida RJ, Adler CH, Adler MW. Morphine-induced mydriasis and fluctuation in the rat: time and dose relationships. Journal of Pharmacology & Experimental Therapeutics. 1979 Jan; 208(1):91-5.
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Adler MW, Adler CH. Toxicity to heavy metals and relationship to seizure thresholds. Clin Pharmacol Ther. 1977 Nov; 22(5 Pt 2):774-9.
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