Simvastatin (Oral Route)

Side Effects

Drug information provided by: Merative, Micromedex®

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

More common

1. Dizziness
2. fainting
3. fast or irregular heartbeat

Less common

1. Bladder pain
2. bloody or cloudy urine
3. blurred vision
4. body aches or pain
5. chills
6. cough
7. dark-colored urine
8. difficult, burning, or painful urination
9. difficulty with breathing
10. difficulty with moving
11. dry mouth
12. ear congestion
13. fever
14. flushed, dry skin
15. frequent urge to urinate
16. fruit-like breath odor
17. headache
18. increased hunger
19. increased thirst
20. increased urination
21. joint pain
22. loss of consciousness
23. lower back or side pain
24. muscle cramps, spasms, stiffness, pain, tenderness, wasting, or weakness
25. nausea
26. runny or stuffy nose
27. sneezing
28. sore throat
29. stomachache
30. sweating
31. swelling
32. swollen joints
33. trouble breathing
34. unexplained weight loss
35. unusual tiredness or weakness
36. vomiting

Incidence not known

1. Blistering, peeling, or loosening of the skin
2. bloating
3. burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings
4. chest tightness
5. constipation
6. diarrhea
7. difficulty with chewing, swallowing, or talking
8. double vision
9. drooping eyelids
10. general tiredness and weakness
11. indigestion
12. large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs
13. light-colored stools
14. loss of appetite
15. muscle pain or weakness
16. pains in the stomach, side, or abdomen, possibly radiating to the back
17. pale skin
18. puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
19. red skin lesions, often with a purple center
20. red, irritated eyes
21. skin rash, hives, or itching
22. sores, ulcers, or white spots in the mouth or on the lips
23. unusual bleeding or bruising
24. upper right abdominal or stomach pain
25. weakness in the arms, hands, legs, or feet
26. yellow eyes or skin

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Less common

1. Acid or sour stomach
2. belching
3. burning feeling in the chest or stomach
4. dizziness or lightheadedness
5. excess air or gas in the stomach or intestines
6. feeling of constant movement of self or surroundings
7. full feeling
8. heartburn
9. lack or loss of strength
10. pain or tenderness around the eyes and cheekbones
11. passing gas
12. sensation of spinning
13. skin rash, encrusted, scaly, and oozing
14. stomach discomfort, upset, or pain
15. tenderness in the stomach area
16. trouble sleeping

Incidence not known

1. Being forgetful
2. depression
3. discoloration of the skin
4. hair loss or thinning of the hair
5. inability to have or keep an erection
6. loss in sexual ability, desire, drive, or performance

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

• Precautions

Portions of this document last updated: July 01, 2024

Copyright: © Merative US L.P. 1973, 2024. All rights reserved. Information is for End User's use only and may not be sold, redistributed or otherwise used for commercial purposes.