Side Effects

Drug information provided by: Merative, Micromedex®

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor or nurse immediately if any of the following side effects occur:

Incidence not known

  1. Agitation
  2. bluish-colored lips, fingernails, or palms
  3. chest tightness
  4. confusion
  5. cough
  6. dark urine
  7. diarrhea
  8. difficulty breathing
  9. difficulty swallowing
  10. dizziness or lightheadedness
  11. fast heartbeat
  12. fever
  13. headache
  14. hives or welts, itching, or skin rash
  15. large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs
  16. overactive reflexes
  17. pale skin
  18. poor coordination
  19. rapid heart rate
  20. redness of the skin
  21. restlessness
  22. shivering
  23. sore throat
  24. sweating
  25. talking or acting with excitement you cannot control
  26. trembling or shaking
  27. twitching
  28. unusual bleeding or bruising
  29. unusual tiredness or weakness

Get emergency help immediately if any of the following symptoms of overdose occur:

Symptoms of overdose

  1. Bigger, dilated, or enlarged pupils (black part of the eye)
  2. blue staining of the urine, skin, and mucous membranes
  3. bluish-colored lips, fingernails, or palms
  4. blurred vision
  5. burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings
  6. chest tightness
  7. confusion
  8. dark urine
  9. difficulty breathing
  10. dizziness or lightheadedness
  11. dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position
  12. fear
  13. fever
  14. headache
  15. increased sensitivity of the eyes to light
  16. nausea
  17. pale skin
  18. rapid heart rate
  19. rapid shallow breathing
  20. shakiness in the legs, arms, hands, or feet
  21. sore throat
  22. stomach pain
  23. unusual bleeding or bruising
  24. unusual tiredness or weakness
  25. vomiting

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

  1. Arm or leg pain
  2. change in taste
  3. changes in skin color
  4. feeling hot or cold
  5. increased sweating
  6. loss of taste
  7. muscle or joint pain
  8. pain at the infusion site

Less common

  1. Back pain
  2. bruising
  3. chills
  4. general feeling of discomfort or illness
  5. large, flat, blue or purplish patches in the skin
  6. loss of appetite
  7. muscle aches and pains
  8. muscle spasm
  9. runny nose
  10. trouble sleeping

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

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Portions of this document last updated: Aug. 01, 2024

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