Description and Brand Names
Drug information provided by: Merative, Micromedex®
Descriptions
Dobutamine and dextrose combination injection is used treat heart failure and helps the heart pump blood.
This medicine is to be given only by or under the supervision of your doctor.
This product is available in the following dosage forms:
Before Using
In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:
Allergies
Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.
Pediatric
Appropriate studies performed to date have not demonstrated pediatric-specific problems that would limit the usefulness of dobutamine and dextrose combination injection in children.
Geriatric
Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of dobutamine and dextrose combination injection in the elderly. However, elderly patients are more likely to have age-related liver, kidney, or heart problems, which may require caution and an adjustment in the dose for patients receiving this medicine.
Breastfeeding
There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.
Drug Interactions
Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are receiving this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.
Using this medicine with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take.
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Isocarboxazid
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Linezolid
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Tranylcypromine
Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.
Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.
Other Interactions
Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.
Other Medical Problems
The presence of other medical problems may affect the use of this medicine. Make sure you tell your doctor if you have any other medical problems, especially:
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Allergy to corn, corn products, or sulfites or
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Heart disease (eg, idiopathic hypertrophic subaortic stenosis)—Should not be used in patients with these conditions.
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Diabetes or
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Heart rhythm problems or
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Hypertension (high blood pressure)—Use with caution. May make these conditions worse.
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Hypovolemia (low blood volume)—Should be corrected first before starting treatment with this medicine.
Proper Use
A nurse or other trained health professional will give you this medicine in a medical facility. It is given as a needle placed into one of your veins.
Precautions
It is very important that your doctor check your progress closely while receiving the medicine to make sure it is working properly. Blood tests are needed to check for unwanted effects.
This medicine may cause increase in blood pressure or heart rate. Check with your doctor right away if you have blurred vision, dizziness, headache, nosebleeds, or numbness or tingling in the face, arms, or legs.
This medicine may cause serious allergic and skin reactions, including anaphylaxis, eosinophilia, and bronchospasms, which can be life-threatening and require immediate medical attention. Check with your doctor right away if you have black, tarry stools, chest pain or tightness, chills, cough, difficulty swallowing, dizziness, fast heartbeat, fever, hives, itching, skin rash, painful or difficult urination, puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue, sore throat, sores, ulcers, or white spots on the lips or in the mouth, swollen glands, trouble breathing, unusual bleeding or bruising, or unusual tiredness or weakness.
This medicine may cause fluid overload, which can lead to electrolyte problems, overhydration, or pulmonary edema (fluid in the lungs). Talk with your doctor right away if you have a decrease in the amount of urine output, noisy, rattling breathing, trouble breathing, swelling of the fingers, hands, feet, or lower legs, or weight gain.
Do not take other medicines unless they have been discussed with your doctor. This includes prescription or nonprescription (over-the-counter [OTC]) medicines and herbal or vitamin supplements.
Side Effects
Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor or nurse immediately if any of the following side effects occur:
More common
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Dizziness
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headache
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increased heart rate
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numbness or tingling in the arms or legs
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trouble thinking, speaking, or walking
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weakness
Less common
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Chest pain
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fast, irregular, pounding, or racing heartbeat or pulse
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trouble breathing
Incidence not known
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Back, tarry stools
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bluish color
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blurred vision
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changes in skin color
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chest discomfort or tightness
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chills
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confusion
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cough
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difficulty swallowing
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dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position
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fever
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hives, itching, skin rash
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painful or difficult urination
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puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
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sore throat
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sores, ulcers, or white spots on the lips or in the mouth
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sweating
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swelling of the fingers, hands, feet, or lower legs
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swollen glands
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unusual bleeding or bruising
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weight gain
Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
Less common
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Nausea
Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.
Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.
Portions of this document last updated: May 01, 2024
Original article: https://www.mayoclinic.org/es/drugs-supplements/dobutamine-and-dextrose-intravenous-route/description/drg-20555999