Before Using
Drug information provided by: Merative, Micromedex®
In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:
Allergies
Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.
Pediatric
Appropriate studies performed to date have not demonstrated pediatric-specific problems that would limit the usefulness of chlorpheniramine, ibuprofen, and pseudoephedrine combination in children 12 years of age and older. This medicine should not be used in children younger than 12 years of age.
Geriatric
Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of chlorpheniramine, ibuprofen, and pseudoephedrine combination in the elderly. However, elderly patients more likely to develop age-related stomach problems, which may require caution and an adjustment in the dose for patients receiving this medicine.
Breastfeeding
Ibuprofen
Studies in women suggest that this medication poses minimal risk to the infant when used during breastfeeding.
Pseudoephedrine
Chlorpheniramine
There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.
Drug Interactions
Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.
Using this medicine with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take.
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Dihydroergotamine
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Furazolidone
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Iproniazid
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Isocarboxazid
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Ketorolac
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Linezolid
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Methylene Blue
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Moclobemide
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Nialamide
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Phenelzine
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Potassium Citrate
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Procarbazine
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Rasagiline
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Safinamide
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Selegiline
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Tranylcypromine
Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.
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Abciximab
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Aceclofenac
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Acemetacin
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Acenocoumarol
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Alfentanil
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Almotriptan
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Amantadine
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Amifampridine
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Amiloride
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Amineptine
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Amitriptyline
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Amitriptylinoxide
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Amoxapine
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Amphetamine
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Amtolmetin Guacil
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Anagrelide
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Apixaban
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Ardeparin
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Argatroban
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Asciminib
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Aspirin
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Balsalazide
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Bemetizide
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Bemiparin
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Bendroflumethiazide
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Benzhydrocodone
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Benzphetamine
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Benzthiazide
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Betrixaban
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Bismuth Subsalicylate
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Bivalirudin
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Bromfenac
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Budesonide
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Bufexamac
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Bumetanide
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Buprenorphine
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Bupropion
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Butorphanol
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Cangrelor
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Carbamazepine
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Celecoxib
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Certoparin
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Chlorothiazide
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Chlorthalidone
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Choline Magnesium Trisalicylate
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Choline Salicylate
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Cilostazol
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Citalopram
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Clomipramine
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Clonixin
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Clopamide
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Clopidogrel
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Clozapine
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Codeine
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Cyclopenthiazide
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Cyclosporine
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Cyclothiazide
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Dabigatran Etexilate
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Dalteparin
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Danaparoid
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Deflazacort
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Desipramine
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Desirudin
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Desmopressin
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Desvenlafaxine
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Dexamethasone
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Dexibuprofen
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Dexketoprofen
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Dextroamphetamine
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Dextromethorphan
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Diazoxide
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Dibenzepin
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Diclofenac
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Diflunisal
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Digoxin
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Dihydrocodeine
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Dipyridamole
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Dipyrone
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Dolasetron
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Donepezil
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Dothiepin
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Doxepin
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Droxicam
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Duloxetine
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Edoxaban
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Emtricitabine
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Enoxaparin
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Eplerenone
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Epoprostenol
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Eptifibatide
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Escitalopram
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Ethacrynic Acid
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Etodolac
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Etofenamate
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Etoricoxib
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Etozolin
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Felbinac
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Fenfluramine
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Fenoprofen
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Fentanyl
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Fepradinol
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Feprazone
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Feverfew
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Floctafenine
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Fluconazole
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Flufenamic Acid
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Fluoxetine
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Flurbiprofen
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Fluvoxamine
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Fondaparinux
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Fosphenytoin
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Furosemide
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Gepirone
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Ginkgo
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Glucagon
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Glycopyrrolate
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Glycopyrronium Tosylate
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Gossypol
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Granisetron
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Guanethidine
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Heparin
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Hydrochlorothiazide
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Hydrocodone
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Hydrocortisone
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Hydroflumethiazide
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Hydromorphone
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Hydroxyamphetamine
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Hydroxytryptophan
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Iloprost
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Imipramine
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Indapamide
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Indomethacin
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Inotersen
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Iobenguane I 123
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Iobenguane I 131
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Ketoprofen
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Lasmiditan
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Lepirudin
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LetibotulinumtoxinA-wlbg
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Levomilnacipran
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Levorphanol
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Lisdexamfetamine
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Lithium
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Lofepramine
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Lorcaserin
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Lornoxicam
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Loxoprofen
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Lumacaftor
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Lumiracoxib
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Mavacamten
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Meadowsweet
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Meclofenamate
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Mefenamic Acid
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Melitracen
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Meloxicam
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Melphalan
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Meperidine
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Mesalamine
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Metaxalone
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Methacholine
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Methadone
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Methamphetamine
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Methotrexate
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Methyclothiazide
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Methyldopa
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Methylene Blue
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Methylprednisolone
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Metolazone
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Midodrine
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Milnacipran
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Mirtazapine
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Morniflumate
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Morphine
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Morphine Sulfate Liposome
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Nabumetone
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Nadroparin
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Nalbuphine
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Naproxen
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Nefazodone
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Nepafenac
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Niflumic Acid
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Nimesulide
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Nimesulide Beta Cyclodextrin
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Nortriptyline
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Olanzapine
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Oliceridine
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Olsalazine Sodium
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Ondansetron
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Opipramol
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Oxaprozin
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Oxycodone
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Oxymorphone
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Oxyphenbutazone
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Palonosetron
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Parecoxib
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Parnaparin
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Paroxetine
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Pemetrexed
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Pentazocine
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Pentosan Polysulfate Sodium
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Pentoxifylline
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Phenindione
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Phenprocoumon
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Phenylbutazone
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Phenytoin
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Piketoprofen
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Piretanide
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Piroxicam
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Pitolisant
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Polythiazide
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Potassium Citrate
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Pranoprofen
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Prasugrel
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Prednisolone
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Prednisone
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Proglumetacin
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Promethazine
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Propyphenazone
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Proquazone
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Protein C
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Protriptyline
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Quetiapine
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Quinethazone
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Remifentanil
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Revefenacin
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Reviparin
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Rivaroxaban
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Rofecoxib
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Salicylic Acid
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Salsalate
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Scopolamine
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Secretin Human
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Selexipag
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Sertraline
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Sibutramine
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Sodium Salicylate
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Sofpironium
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Spironolactone
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Sufentanil
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Sulfasalazine
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Sulfinpyrazone
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Sulindac
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Sulodexide
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Tacrolimus
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Tapentadol
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Tenofovir Alafenamide
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Tenofovir Disoproxil Fumarate
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Tenoxicam
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Tianeptine
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Tiaprofenic Acid
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Ticagrelor
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Ticlopidine
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Tinzaparin
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Tiotropium
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Tirofiban
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Tolfenamic Acid
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Tolmetin
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Torsemide
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Tramadol
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Trazodone
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Treprostinil
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Triamterene
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Trichlormethiazide
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Trimipramine
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Upadacitinib
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Valdecoxib
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Venlafaxine
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Vilazodone
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Vorapaxar
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Vortioxetine
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Warfarin
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Xipamide
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Zavegepant
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Ziprasidone
Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.
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Acebutolol
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Amikacin
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Atenolol
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Azilsartan
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Azilsartan Medoxomil
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Benazepril
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Betaxolol
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Bisoprolol
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Candesartan
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Captopril
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Carteolol
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Carvedilol
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Celiprolol
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Enalapril
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Enalaprilat
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Eprosartan
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Esmolol
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Fosinopril
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Irbesartan
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Labetalol
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Levobunolol
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Lisinopril
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Losartan
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Metipranolol
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Metoprolol
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Moexipril
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Nadolol
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Nebivolol
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Olmesartan
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Oxprenolol
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Penbutolol
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Perindopril
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Pindolol
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Propranolol
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Quinapril
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Ramipril
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Sotalol
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Spirapril
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Telmisartan
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Timolol
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Trandolapril
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Valsartan
Other Interactions
Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.
Using this medicine with any of the following is usually not recommended, but may be unavoidable in some cases. If used together, your doctor may change the dose or how often you use this medicine, or give you special instructions about the use of food, alcohol, or tobacco.
Other Medical Problems
The presence of other medical problems may affect the use of this medicine. Make sure you tell your doctor if you have any other medical problems, especially:
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Allergy to aspirin or
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Asthma or
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Diabetes or
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Glaucoma or
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Heart attack, history of or
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Heart disease or
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High blood pressure, history of or
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Kidney disease or
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Liver disease (eg, cirrhosis) or
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Lung or breathing problems (eg, bronchitis, emphysema)
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Stomach ulcers or bleeding, history of or
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Stroke, history of or
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Thyroid problems or
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Trouble urinating caused by enlarged prostate—Use with caution. May make these conditions worse.
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Heart surgery—Should not be used to relieve pain right before or after the surgery.
Portions of this document last updated: Aug. 01, 2024
Copyright: © Merative US L.P. 1973, 2024. All rights reserved. Information is for End User's use only and may not be sold, redistributed or otherwise used for commercial purposes.