Description and Brand Names
Drug information provided by: Merative, Micromedex®
Canadian Brand Name
- Pms-Asa Suppository Adult
- Pms-Asa Suppository Children
- Supasa
Descriptions
Aspirin suppository is used to relieve minor aches, pains, and headache and to reduce fever.
This medicine is available as an over-the-counter (OTC) product.
This product is available in the following dosage forms:
Before Using
In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:
Allergies
Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.
Pediatric
Appropriate studies have not been performed on the relationship of age to the effects of aspirin suppository in children younger than 12 years of age. Safety and efficacy have not been established.
Geriatric
No information is available on the relationship of age to the effects of aspirin suppository in geriatric patients.
Breastfeeding
There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.
Drug Interactions
Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.
Using this medicine with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take.
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Abrocitinib
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Defibrotide
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Dichlorphenamide
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Influenza Virus Vaccine, Live
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Ketorolac
Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.
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Acarbose
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Aceclofenac
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Acemetacin
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Acenocoumarol
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Acetazolamide
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Alclometasone
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Aldosterone
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Alipogene Tiparvovec
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Alteplase, Recombinant
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Amcinonide
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Amikacin
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Amiloride
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Amineptine
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Amitriptyline
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Amitriptylinoxide
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Amoxapine
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Amphotericin B
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Amtolmetin Guacil
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Anagrelide
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Anisindione
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Apixaban
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Ardeparin
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Argatroban
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Bacitracin
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Beclomethasone
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Bemetizide
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Bemiparin
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Benazepril
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Bendroflumethiazide
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Benzthiazide
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Betamethasone
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Betrixaban
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Bivalirudin
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Brinzolamide
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Bromfenac
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Budesonide
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Bufexamac
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Bumetanide
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Caplacizumab-yhdp
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Capreomycin
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Captopril
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Celecoxib
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Certoparin
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Chlorothiazide
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Chlorpropamide
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Chlorthalidone
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Choline Salicylate
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Ciclesonide
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Cilostazol
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Cisplatin
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Citalopram
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Clobetasol
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Clobetasone
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Clocortolone
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Clomipramine
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Clonixin
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Clopamide
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Clopidogrel
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Cortisone
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Curcumin
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Cyclopenthiazide
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Cyclosporine
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Cyclothiazide
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Dabigatran Etexilate
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Dalteparin
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Danaparoid
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Deflazacort
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Desipramine
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Desirudin
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Desmopressin
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Desonide
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Desoximetasone
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Desvenlafaxine
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Dexamethasone
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Dexibuprofen
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Dexketoprofen
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Diazoxide
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Dibenzepin
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Diclofenac
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Dicumarol
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Diflorasone
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Diflucortolone
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Diflunisal
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Difluprednate
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Digoxin
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Dipyrone
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Dorzolamide
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Dothiepin
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Doxepin
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Droxicam
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Duloxetine
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Edoxaban
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Emtricitabine
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Enalapril
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Enalaprilat
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Enoxaparin
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Eplerenone
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Eptifibatide
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Escitalopram
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Ethacrynic Acid
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Etodolac
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Etofenamate
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Etoricoxib
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Etozolin
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Felbinac
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Fenoprofen
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Fepradinol
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Feprazone
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Feverfew
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Floctafenine
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Flucloronide
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Fludrocortisone
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Flufenamic Acid
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Flumethasone
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Flunisolide
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Fluocinolone
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Fluocinonide
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Fluocortin
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Fluocortolone
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Fluorometholone
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Fluoxetine
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Flurandrenolide
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Flurbiprofen
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Fluticasone
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Fluvoxamine
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Fondaparinux
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Foscarnet
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Fosinopril
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Fosphenytoin
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Furosemide
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Gentamicin
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Ginkgo
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Glimepiride
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Glipizide
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Glyburide
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Gossypol
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Halcinonide
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Halobetasol
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Heparin
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Hydrochlorothiazide
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Hydrocortisone
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Hydroflumethiazide
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Ibrutinib
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Ibuprofen
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Imipramine
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Indapamide
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Indomethacin
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Inotersen
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Kanamycin
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Ketoprofen
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Lepirudin
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Levomilnacipran
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Lisinopril
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Lithium
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Lofepramine
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Lornoxicam
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Loteprednol
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Loxoprofen
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Lumiracoxib
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Macimorelin
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Meclofenamate
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Medrysone
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Mefenamic Acid
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Melitracen
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Meloxicam
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Melphalan
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Metformin
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Methazolamide
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Methotrexate
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Methyclothiazide
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Methylprednisolone
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Metolazone
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Milnacipran
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Moexipril
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Mometasone
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Morniflumate
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Nabumetone
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Nadroparin
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Naproxen
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Nateglinide
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Nefazodone
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Neomycin
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Nepafenac
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Netilmicin
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Nicorandil
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Niflumic Acid
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Nimesulide
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Nimesulide Beta Cyclodextrin
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Nortriptyline
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Opipramol
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Oxaprozin
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Oxyphenbutazone
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Paramethasone
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Parecoxib
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Parnaparin
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Paromomycin
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Paroxetine
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Pemetrexed
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Pentosan Polysulfate Sodium
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Pentoxifylline
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Perindopril
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Phenindione
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Phenprocoumon
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Phenylbutazone
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Phenytoin
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Piketoprofen
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Piracetam
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Piretanide
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Piroxicam
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Plazomicin
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Polythiazide
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Potassium Citrate
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Pranoprofen
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Prasugrel
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Prednicarbate
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Prednisolone
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Prednisone
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Proglumetacin
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Propyphenazone
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Proquazone
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Protein C
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Protriptyline
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Quinapril
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Quinethazone
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Ramipril
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Repaglinide
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Reteplase, Recombinant
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Reviparin
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Rimexolone
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Rivaroxaban
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Rofecoxib
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Salicylic Acid
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Salsalate
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Selumetinib
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Sertraline
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Sodium Salicylate
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Spectinomycin
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Spirapril
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Spironolactone
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Streptomycin
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Sulindac
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Sulodexide
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Tacrolimus
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Tenofovir Alafenamide
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Tenofovir Disoproxil Fumarate
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Tenoxicam
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Tianeptine
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Tiaprofenic Acid
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Ticagrelor
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Ticlopidine
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Tinzaparin
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Tirofiban
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Tobramycin
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Tolazamide
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Tolbutamide
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Tolfenamic Acid
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Tolmetin
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Torsemide
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Trandolapril
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Trazodone
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Treprostinil
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Triamcinolone
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Triamterene
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Trichlormethiazide
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Trimipramine
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Turmeric
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Upadacitinib
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Valdecoxib
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Valproic Acid
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Vancomycin
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Varicella Virus Vaccine, Live
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Venlafaxine
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Vilazodone
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Vortioxetine
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Warfarin
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Xipamide
Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.
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Acebutolol
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Atenolol
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Betaxolol
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Bisoprolol
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Carteolol
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Carvedilol
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Celiprolol
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Delapril
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Esmolol
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Imidapril
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Labetalol
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Levobunolol
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Metipranolol
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Metoprolol
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Nadolol
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Nebivolol
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Nitroglycerin
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Oxprenolol
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Penbutolol
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Pindolol
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Probenecid
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Propranolol
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Sotalol
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Streptokinase
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Tamarind
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Temocapril
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Tenecteplase
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Timolol
Other Interactions
Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.
Other Medical Problems
The presence of other medical problems may affect the use of this medicine. Make sure you tell your doctor if you have any other medical problems, especially:
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Chicken pox or
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Flu—Should not be used in patients who are recovering from these conditions.
Proper Use
Use this medicine only as directed by your doctor. Do not use more of it, do not use it more often, and do not use it for a longer time than your doctor ordered.
Follow the instructions on the medicine label if you are using this medicine without a prescription.
To use the suppository:
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Remove the suppository from plastic packet.
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Lie down on your side and use your finger to push the suppository well up into the rectum.
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Remain lying down for about 15 minutes to keep the suppository from coming out before it melts.
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Make sure to wash your hands with soap and water before and after inserting this medicine.
Tell your doctor if you drink 3 or more alcoholic drinks every day. Drinking alcoholic beverages while taking this medicine may increase your risk of stomach bleeding.
Dosing
The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.
The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.
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For rectal dosage form (suppository):
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For minor aches and pains:
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Adults and children 12 years of age and older—1 suppository inserted into your rectum every 4 hours. Do not use for more than 10 days.
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Children younger than 12 years of age—Use and dose must be determined by your doctor.
Missed Dose
If you miss a dose of this medicine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.
Storage
You may store the suppositories in the refrigerator, but do not freeze them.
Keep out of the reach of children.
Do not keep outdated medicine or medicine no longer needed.
Ask your healthcare professional how you should dispose of any medicine you do not use.
Precautions
It is very important that your doctor check your or your child's progress at regular visits to make sure that this medicine is working properly and to check for unwanted effects.
Using this medicine during late pregnancy can harm your unborn baby. If you think you have become pregnant while using the medicine, tell your doctor right away.
Aspirin can cause a rare but serious illness called Reye's syndrome in children and teenagers. Call you doctor right away if your child has behavior changes along with nausea and vomiting while using this medicine.
Do not take other medicines unless they have been discussed with your doctor. This includes prescription or non-prescription (over-the-counter [OTC]) medicines and herbal or vitamin supplements.
Side Effects
Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor immediately if any of the following side effects occur:
Incidence not known
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Nausea and vomiting
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seizures
Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.
Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.
Portions of this document last updated: Aug. 01, 2024
Original article: https://www.mayoclinic.org/es/drugs-supplements/aspirin-rectal-route/side-effects/drg-20554222