Amoxicillin (Oral Route)

Side Effects

Drug information provided by: Merative, Micromedex®

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

Less common

1. Itching of the vagina or genitals
2. thick, white vaginal discharge with mild or no odor

Incidence not known

1. Back, leg, or stomach pains
2. black, tarry stools
3. bleeding gums
4. blistering, peeling, or loosening of the skin
5. bloating
6. blood in the urine
7. bloody nose
8. blurred vision
9. chest pain or tightness
10. chills
11. clay-colored stools
12. cold clammy skin
13. confusion
14. cough
15. dark urine
16. diarrhea
17. diarrhea, watery and severe, which may also be bloody
18. difficulty with breathing
19. difficulty with swallowing
20. dizziness
21. dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position
22. fast heartbeat
23. feeling of discomfort
24. fever
25. general body swelling
26. headache
27. heavier menstrual periods
28. hives or welts
29. increased thirst
30. inflammation of the joints
31. itching
32. joint or muscle pain
33. loss of appetite
34. lower back pain
35. muscle aches
36. nausea or vomiting
37. nosebleeds
38. pain
39. pain or burning while urinating
40. painful or difficult urination
41. pale skin
42. pinpoint red spots on the skin
43. puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
44. rash
45. red, irritated eyes
46. redness, soreness, or itching skin
47. red skin lesions, often with a purple center
48. sore throat
49. sores, ulcers, or white spots in the mouth or on the lips
50. sores, welting, or blisters
51. stomach cramps or tenderness
52. sudden decrease in the amount of urine
53. sweating
54. swollen, lymph glands
55. tenderness
56. unpleasant breath odor
57. unusual bleeding or bruising
58. unusual drowsiness, dullness, tiredness, weakness or feeling of sluggishness
59. unusual tiredness or weakness
60. unusual weight loss
61. vomiting of blood
62. watery or bloody diarrhea
63. yellow eyes or skin

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Less common

1. Bad, unusual, or unpleasant (after) taste
2. change in taste

Incidence not known

1. Agitation
2. black, hairy tongue
3. changes in behavior
4. discoloration of the tooth (brown, yellow, or gray staining)
5. seizures
6. sleeplessness
7. trouble with sleeping
8. unable to sleep
9. white patches in the mouth or throat or on the tongue
10. white patches with diaper rash

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

• Precautions

Portions of this document last updated: June 01, 2024

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