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Vijay Shah, M.D.

  1. Gastroenterologist
  2. Transplant Hepatologist
  3. Chair, Gastroenterology and Hepatology, Minnesota
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Publicaciones

  1. Ramkissoon R, Cao S, Shah VH. The Pathophysiology of Portal Hypertension. Clin Liver Dis. 2024 Aug; 28 (3):369-381 Epub 2024 Apr 27
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  2. Tapper EB, Goldberg D, Parikh ND, Terrault NA, Welch N, Sharpton S, Hameed B, Khalili M, Stolz A, Verna EC, Brown RS Jr, Sanyal AJ, VanWagner L, Ladner DP, Moylan CA, Diehl AM, Jones PD, Loomba RC, Dasarathy S, Simonetto DA, Shah VH, Bajaj JS, LCN Study Group. The Liver Cirrhosis Network Cohort Study: Cirrhosis Definition, Study Population, and Endpoints. Am J Gastroenterol. 2024 Jul 17 Epub 2024 July 17
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  3. Singal AK, Shah VH, Malhi H. Emerging targets for therapy in ALD: Lessons from NASH. Hepatology. 2024 Jul 1; 80 (1):223-237 Epub 2023 Mar 21
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  4. Khanal S, Liu Y, Bamidele AO, Wixom AQ, Washington AM, Jalan-Sakrikar N, Cooper SA, Vuckovic I, Zhang S, Zhong J, Johnson KL, Charlesworth MC, Kim I, Yeon Y, Yoon S, Noh YK, Meroueh C, Timbilla AA, Yaqoob U, Gao J, Kim Y, Lucien F, Huebert RC, Hay N, Simons M, Shah VH, Kostallari E. Glycolysis in hepatic stellate cells coordinates fibrogenic extracellular vesicle release spatially to amplify liver fibrosis. Sci Adv. 2024 Jun 28; 10 (26):eadn5228 Epub 2024 June 28
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  5. Gao J, Lan T, Kostallari E, Guo Y, Lai E, Guillot A, Ding B, Tacke F, Tang C, Shah VH. Angiocrine signaling in sinusoidal homeostasis and liver diseases. J Hepatol. 2024 May 17 [Epub ahead of print]
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  6. Narayanan P, Wu T, Shah VH, Curtis BL. Insights into ALD and AUD diagnosis and prognosis: Exploring AI and multimodal data streams. Hepatology. 2024 May 14 [Epub ahead of print]
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  7. Gan C, Yaqoob U, Lu J, Xie M, Anwar A, Jalan-Sakrikar N, Jerez S, Sehrawat TS, Navarro-Corcuera A, Kostallari E, Habash NW, Cao S, Shah VH. Liver sinusoidal endothelial cells contribute to portal hypertension through collagen type IV-driven sinusoidal remodeling. JCI Insight. 2024 May 7; 9 (11) Epub 2024 May 07
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  8. Gawrieh S, Dasarathy S, Tu W, Kamath PS, Chalasani NP, McClain CJ, Bataller R, Szabo G, Tang Q, Radaeva S, Barton B, Nagy LE, Shah VH, Sanyal AJ, Mitchell MC, AlcHepNet Investigators. Randomized trial of anakinra plus zinc vs. prednisone for severe alcohol-associated hepatitis. J Hepatol. 2024 May; 80 (5):684-693 Epub 2024 Feb 10
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  9. Sordi Chara B, Hara KS, Penrice D, Schmidt KA, Kassmeyer BA, Anstey J, Tiede D, Kamath PS, Shah VH, Bajaj JS, Kraus A, Simonetto DA. Artificial Intelligence-Enabled Stool Analysis for Lactulose Titration Assistance in Hepatic Encephalopathy Through a Smartphone Application. Am J Gastroenterol. 2024 May 1; 119 (5):982-986 Epub 2024 Jan 19
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  10. Dunn W, Li Y, Singal AK, Simonetto DA, Diaz LA, Idalsoaga F, Ayares G, Arnold J, Ayala-Valverde M, Perez D, Gomez J, Escarate R, Fuentes-Lopez E, Ramirez-Cadiz C, Morales-Arraez D, Zhang W, Qian S, Ahn JC, Buryska S, Mehta H, Dunn N, Waleed M, Stefanescu H, Bumbu A, Horhat A, Attar B, Agrawal R, Cabezas J, Echavaria V, Cuyas B, Poca M, Soriano G, Sarin SK, Maiwall R, Jalal PK, Higuera-de-la-Tijera F, Kulkarni AV, Rao PN, Guerra-Salazar P, Skladany L, Kubanek N, Prado V, Clemente-Sanchez A, Rincon D, Haider T, Chacko KR, Romero GA, Pollarsky FD, Restrepo JC, Toro LG, Yaquich P, Mendizabal M, Garrido ML, Marciano S, Dirchwolf M, Vargas V, Jimenez C, Hudson D, Garcia-Tsao G, Ortiz G, Abraldes JG, Kamath PS, Arrese M, Shah VH, Bataller R, Arab JP. An artificial intelligence-generated model predicts 90-day survival in alcohol-associated hepatitis: A global cohort study. Hepatology. 2024 Apr 12 [Epub ahead of print]
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  11. Meroueh C, Warasnhe K, Tizhoosh HR, Shah VH, Ibrahim SH. Digital pathology and spatial omics in steatohepatitis: Clinical applications and discovery potentials. Hepatology. 2024 Mar 22 [Epub ahead of print]
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  12. Guan Y, Peiffer B, Feng D, Parra MA, Wang Y, Fu Y, Shah VH, Cameron AM, Sun Z, Gao B. IL-8+ neutrophils drive inexorable inflammation in severe alcohol-associated hepatitis. J Clin Invest. 2024 Mar 19; 134 (9)
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  13. Diaz LA, Fuentes-Lopez E, Idalsoaga F, Ayares G, Corsi O, Arnold J, Cannistra M, Vio D, Marquez-Lomas A, Ramirez-Cadiz C, Medel MP, Hernandez-Tejero M, Ferreccio C, Lazo M, Roblero JP, Cotter TG, Kulkarni AV, Kim W, Brahmania M, Louvet A, Tapper EB, Dunn W, Simonetto D, Shah VH, Kamath PS, Lazarus JV, Singal AK, Bataller R, Arrese M, Arab JP. Association between public health policies on alcohol and worldwide cancer, liver disease and cardiovascular disease outcomes. J Hepatol. 2024 Mar; 80 (3):409-418 Epub 2023 Nov 21
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  14. Wang Y, Wang X, Bai B, Shaha A, He X, He Y, Ye Z, Shah VH, Kang N. Targeting Src SH3 domain-mediated glycolysis of HSC suppresses transcriptome, myofibroblastic activation, and colorectal liver metastasis. Hepatology. 2024 Jan 24 [Epub ahead of print]
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  15. Jophlin LL, Singal AK, Bataller R, Wong RJ, Sauer BG, Terrault NA, Shah VH. ACG Clinical Guideline: Alcohol-Associated Liver Disease. Am J Gastroenterol. 2024 Jan 1; 119 (1):30-54 Epub 2023 Sept 01
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  16. Bhala N, Mellinger J, Asrani SK, Shah VH. Tackling the burden of preventable liver disease in the USA. Lancet Gastroenterol Hepatol. 2024 Jan; 9 (1):9-10 Epub 2023 Nov 11
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  17. Maheshwari S, Gu CN, Caserta MP, Kezer CA, Shah VH, Torbenson MS, Menias CO, Fidler JL, Venkatesh SK. Imaging of Alcohol-Associated Liver Disease. AJR Am J Roentgenol. 2024 Jan; 222 (1):e2329917 Epub 2023 Sept 20
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  18. Wu T, Sherman G, Giorgi S, Thanneeru P, Ungar LH, Kamath PS, Simonetto DA, Curtis BL, Shah VH. Smartphone sensor data estimate alcohol craving in a cohort of patients with alcohol-associated liver disease and alcohol use disorder. Hepatol Commun. 2023 Dec 1; 7 (12) Epub 2023 Dec 07
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  19. Avitabile E, Diaz A, Montironi C, Perez-Guasch M, Gratacos-Gines J, Hernandez-Evole H, Moreira RK, Sehrawat TS, Malhi H, Olivas P, Hernandez-Gea V, Bataller R, Shah VH, Kamath PS, Gines P, Pose E. Adding inflammatory markers and refining national institute on alcohol abuse and alcoholism criteria improve diagnostic accuracy for alcohol-associated hepatitis. Clinical Gastroenterology and Hepatology. 2023 Nov; 21 (12):3080-8.e9
  20. Avitabile E, Diaz A, Montironi C, Perez-Guasch M, Gratacos-Gines J, Hernandez-Evole H, Moreira RK, Sehrawat TS, Malhi H, Olivas P, Hernandez-Gea V, Bataller R, Shah VH, Kamath PS, Gines P, Pose E. Adding Inflammatory Markers and Refining National Institute on Alcohol Abuse and Alcoholism Criteria Improve Diagnostic Accuracy for Alcohol-associated Hepatitis. Clin Gastroenterol Hepatol. 2023 Nov; 21 (12):3080-3088.e9 Epub 2023 Mar 31
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  21. Li J, Lu X, Zhu Z, Kalutkiewicz KJ, Mounajjed T, Therneau TM, Venkatesh SK, Sui Y, Glaser KJ, Hoodeshenas S, Manduca A, Shah VH, Ehman RL, Allen AM, Yin M. Head-to-head comparison of magnetic resonance elastography-based liver stiffness, fat fraction, and T1 relaxation time in identifying at-risk NASH. Hepatology. 2023 Oct 1; 78 (4):1200-1208 Epub 2023 May 01
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  22. Cooper SA, Kostallari E, Shah VH. Angiocrine Signaling in Sinusoidal Health and Disease. Semin Liver Dis. 2023 Aug; 43 (3):245-257 Epub 2023 July 13
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  23. Kezer CA, Simonetto DA, Shah VH. Acute on Chronic Liver Failure in Patients with Alcohol-Associated Hepatitis: A Review. Clin Liver Dis. 2023 Aug; 27 (3):659-670 Epub 2023 Apr 24
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  24. Diaz LA, Fuentes-Lopez E, Ayares G, Idalsoaga F, Arnold J, Valverde MA, Perez D, Gomez J, Escarate R, Villalon A, Ramirez CA, Hernandez-Tejero M, Zhang W, Qian S, Simonetto DA, Ahn JC, Buryska S, Dunn W, Mehta H, Agrawal R, Cabezas J, Garcia-Carrera I, Cuyas B, Poca M, Soriano G, Sarin SK, Maiwall R, Jalal PK, Abdulsada S, Higuera-de-la-Tijera F, Kulkarni AV, Rao PN, Salazar PG, Skladany L, Bystrianska N, Clemente-Sanchez A, Villaseca-Gomez C, Haider T, Chacko KR, Romero GA, Pollarsky FD, Restrepo JC, Castro-Sanchez S, Toro LG, Yaquich P, Mendizabal M, Garrido ML, Marciano S, Dirchwolf M, Vargas V, Jimenez C, Louvet A, Garcia-Tsao G, Roblero JP, Abraldes JG, Shah VH, Kamath PS, Arrese M, Singal AK, Bataller R, Arab JP. MELD 3.0 adequately predicts mortality and renal replacement therapy requirements in patients with alcohol-associated hepatitis. JHEP Rep. 2023 Aug; 5 (8):100727 Epub 2023 Mar 15
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  25. Malhi H, Shah V, Gores GJ. Thematic reviews: The future of hepatology. Hepatology 2023 Aug 1; 78 (2):388 Epub 2023 Apr 19
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  26. Ahn JC, Wi CI, Buryska S, Sivasubramaniam P, Harmsen WS, Kamath PS, Simonetto DA, Juhn Y, Shah VH. Disproportionate increases in alcohol-associated hepatitis incidence in women and individuals of low socioeconomic status: A population-based study using the Rochester epidemiology project database. Hepatol Commun. 2023 Jun 1; 7 (6) Epub 2023 May 31
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  27. Tu W, Gawrieh S, Dasarathy S, Mitchell MC, Simonetto DA, Patidar KR, McClain CJ, Bataller R, Szabo G, Tang Q, Barton BA, Radaeva S, Sanyal AJ, Shah V, Alcoholic Hepatitis Network (AlcHepNet) Investigators. Design of a multicenter randomized clinical trial for treatment of Alcohol-Associated Hepatitis. Contemp Clin Trials Commun. 2023 Apr; 32:101074 Epub 2023 Jan 18
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  28. Argemi J, Latasa MU, Atkinson SR, Blokhin IO, Massey V, Gue JP, Cabezas J, Lozano JJ, Van Booven D, Bell A, Cao S, Vernetti LA, Arab JP, Ventura-Cots M, Edmunds LR, Fondevila C, Starkel P, Dubuquoy L, Louvet A, Odena G, Gomez JL, Aragon T, Altamirano J, Caballeria J, Jurczak MJ, Taylor DL, Berasain C, Wahlestedt C, Monga SP, Morgan MY, Sancho-Bru P, Mathurin P, Furuya S, Lackner C, Rusyn I, Shah VH, Thursz MR, Mann J, Avila MA, Bataller R. Author Correction: Defective HNF4alpha-dependent gene expression as a driver of hepatocellular failure in alcoholic hepatitis. Nat Commun. 2023 Feb 10; 14 (1):757
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  29. Murad MH, Swift MD, Razonable RR, Tande AJ, Wilson JW, Kasten MJ, Sia IG, Matey JN, Vanichkachorn G, Caine NA, Shah V, O'Horo J, Destro Borgen MJ, Cowl CT, Berbari EF. Integrating Infectious Diseases and Preventive Medicine Specialties Into 1 Division: Experience of an Academic Medical Center. Mayo Clin Proc. 2023 Feb; 98 (2):224-228
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  30. Li J, Allen AM, Shah VH, Manduca A, Ehman RL, Yin M, NAFLD MR Imaging Research Group. Longitudinal Changes in MR Elastography-based Biomarkers in Obese Patients Treated with Bariatric Surgery. Clin Gastroenterol Hepatol. 2023 Jan; 21 (1):220-222.e3 Epub 2021 Oct 30
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  31. Argemi J, Latasa MU, Atkinson SR, Blokhin IO, Massey V, Gue JP, Cabezas J, Lozano JJ, Van Booven D, Bell A, Cao S, Vernetti LA, Arab JP, Ventura-Cots M, Edmunds LR, Fondevila C, Dubuquoy L, Louvet A, Odena G, Gomez JL, Aragon T, Altamirano J, Caballeria J, Jurczak MJ, Taylor DL, Berasain C, Wahlestedt C, Monga SP, Morgan MY, Sancho-Bru P, Mathurin P, Furuya S, Lackner C, Rusyn I, Shah VH, Thursz MR, Mann J, Avila MA, Bataller R. Erratum: Author Correction: Defective HNF4alpha-dependent gene expression as a driver of hepatocellular failure in alcoholic hepatitis (Nature communications (2019) 10 1 (3126)). Nature communications. 2023; 14 (1):757
  32. Bataller R, Arab JP, Shah VH. Alcohol-Associated Hepatitis. N Engl J Med. 2022 Dec 29; 387 (26):2436-2448
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  33. Singal AK, DiMartini A, Leggio L, Arab JP, Kuo YF, Shah VH. Identifying Alcohol Use Disorder in Patients With Cirrhosis Reduces 30-Days Readmission Rate. Alcohol Alcohol. 2022 Sep 10; 57 (5):576-580
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  34. Ventura-Cots M, Argemi J, Jones PD, Lackner C, El Hag M, Abraldes JG, Alvarado E, Clemente A, Ravi S, Alves A, Alboraie M, Altamirano J, Barace S, Bosques F, Brown R, Caballeria J, Cabezas J, Carvalhana S, Cortez-Pinto H, Costa A, Degre D, Fernandez-Carrillo C, Ganne-Carrie N, Garcia-Tsao G, Genesca J, Koskinas J, Lanthier N, Louvet A, Lozano JJ, Lucey MR, Masson S, Mathurin P, Mendez-Sanchez N, Miquel R, Moreno C, Mounajjed T, Odena G, Kim W, Sancho-Bru P, Warren Sands R, Szafranska J, Verset L, Schnabl B, Sempoux C, Shah V, Shawcross DL, Stauber RE, Straub BK, Verna E, Tiniakos D, Trepo E, Vargas V, Villanueva C, Woosley JT, Ziol M, Mueller S, Starkel P, Bataller R. Clinical, histological and molecular profiling of different stages of alcohol-related liver disease. Gut. 2022 Sep; 71 (9):1856-1866 Epub 2022 Jan 06
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  35. Greuter T, Yaqoob U, Gan C, Jalan-Sakrikar N, Kostallari E, Lu J, Gao J, Sun L, Liu M, Sehrawat TS, Ibrahim SH, Furuta K, Nozickova K, Huang BQ, Gao B, Simons M, Cao S, Shah VH. Mechanotransduction-induced glycolysis epigenetically regulates a CXCL1-dominant angiocrine signaling program in liver sinusoidal endothelial cells in vitro and in vivo. J Hepatol. 2022 Sep; 77 (3):723-734 Epub 2022 Apr 12
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  36. Caine NA, Ebbert JO, Raffals LE, Philpot LM, Sundsted KK, Mikhail AE, Issa M, Schletty AA, Shah VH. A 2030 Vision for the Mayo Clinic Department of Medicine. Mayo Clin Proc. 2022 Jul; 97 (7):1232-1236
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  37. Ahn JC, Noh YK, Rattan P, Buryska S, Wu T, Kezer CA, Choi C, Arunachalam SP, Simonetto DA, Shah VH, Kamath PS. Machine Learning Techniques Differentiate Alcohol-Associated Hepatitis From Acute Cholangitis in Patients With Systemic Inflammation and Elevated Liver Enzymes. Mayo Clin Proc. 2022 Jul; 97 (7):1326-1336
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  38. Rattan P, Shah VH. Review article: current and emerging therapies for acute alcohol-associated hepatitis. Aliment Pharmacol Ther. 2022 Jul; 56 (1):28-40 Epub 2022 May 14
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  39. Wu T, Cooper SA, Shah VH. Omics and AI advance biomarker discovery for liver disease. Nat Med 2022 Jun; 28 (6):1131-1132
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  40. Szabo G, Thursz M, Shah VH. Therapeutic advances in alcohol-associated hepatitis. J Hepatol. 2022 Jun; 76 (6):1279-1290
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  41. Choi C, Lennon RJ, Choi DH, Serafim LP, Allen AM, Kamath PS, Shah VH, de Moraes AG, Simonetto DA. Relationship Between Body Mass Index and Survival Among Critically Ill Patients With Cirrhosis. J Intensive Care Med. 2022 Jun; 37 (6):817-824 Epub 2021 July 05
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  42. Caine, NA, Ebbert JO, Raffals L, Philpot L, Sundsted K, Mikhail AE, Issa M, Schletty A, Shah VH. Perspective and Controversy: A 2030 Vision for the Mayo Clinic Department of Medicine Mayo Clinic Proceedings. 2022.
  43. Muthiah MD, Smirnova E, Puri P, Chalasani N, Shah VH, Kiani C, Taylor S, Mirshahi F, Sanyal AJ. Development of Alcohol-Associated Hepatitis Is Associated With Specific Changes in Gut-Modified Bile Acids. Hepatol Commun. 2022 May; 6 (5):1073-1089 Epub 2022 Jan 04
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  44. Morales-Arraez D, Ventura-Cots M, Altamirano J, Abraldes JG, Cruz-Lemini M, Thursz MR, Atkinson SR, Sarin SK, Kim W, Chavez-Araujo R, Higuera-de la Tijera MF, Singal AK, Shah VH, Kamath PS, Duarte-Rojo A, Charles EA, Vargas V, Jager M, Rautou PE, Rincon D, Zamarripa F, Restrepo-Gutierrez JC, Torre A, Lucey MR, Arab JP, Mathurin P, Louvet A, Garcia-Tsao G, Gonzalez JA, Verna EC, Brown RS Jr, Argemi J, Fernandez-Carrillo C, Clemente A, Alvarado-Tapias E, Forrest E, Allison M, Bataller R. Correction to: The MELD Score Is Superior to the Maddrey Discriminant Function Score to Predict Short-Term Mortality in Alcohol-Associated Hepatitis: A Global Study. Am J Gastroenterol. 2022 May 1; 117 (5):818
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  45. Habash NW, Sehrawat TS, Shah VH, Cao S. Epigenetics of alcohol-related liver diseases. JHEP Rep. 2022 May; 4 (5):100466 Epub 2022 Mar 10
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  46. Navarro-Corcuera A, Sehrawat TS, Jalan-Sakrikar N, Gibbons HR, Pirius NE, Khanal S, Hamdan FH, Aseem SO, Cao S, Banales JM, Kang N, Faubion WA, LaRusso NF, Shah VH, Huebert RC. Long non-coding RNA ACTA2-AS1 promotes ductular reaction by interacting with the p300/ELK1 complex. J Hepatol. 2022 Apr; 76 (4):921-933 Epub 2021 Dec 23
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  47. Singal AK, Kwo P, Kwong A, Liangpunsakul S, Louvet A, Mandrekar P, McClain C, Mellinger J, Szabo G, Terrault N, Thursz M, Winder GS, Kim WR, Shah VH. Research methodologies to address clinical unmet needs and challenges in alcohol-associated liver disease. Hepatology. 2022 Apr; 75 (4):1026-1037 Epub 2021 Nov 27
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  48. Wu T, Simonetto DA, Halamka JD, Shah VH. The digital transformation of hepatology: The patient is logged in. Hepatology. 2022 Mar; 75 (3):724-739 Epub 2022 Jan 31
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  49. Ahn JC, Attia ZI, Rattan P, Mullan AF, Buryska S, Allen AM, Kamath PS, Friedman PA, Shah VH, Noseworthy PA, Simonetto DA. Development of the AI-Cirrhosis-ECG Score: An Electrocardiogram-Based Deep Learning Model in Cirrhosis. Am J Gastroenterol. 2022 Mar 1; 117 (3):424-432
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  50. Kezer CA, Buryska SM, Ahn JC, Harmsen WS, Dunn W, Singal AK, Arab JP, Diaz LA, Arnold J, Kamath PS, Shah VH, Simonetto DA. The Mortality Index for Alcohol-Associated Hepatitis: A Novel Prognostic Score. Mayo Clin Proc. 2022 Mar; 97 (3):480-490 Epub 2022 Feb 15
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  51. Buchl SC, Hanquier Z, Haak AJ, Thomason YM, Huebert RC, Shah VH, Maiers JL. Traf2 and NCK Interacting Kinase Is a Critical Regulator of Procollagen I Trafficking and Hepatic Fibrogenesis in Mice. Hepatol Commun. 2022 Mar; 6 (3):593-609 Epub 2021 Oct 22
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  52. Cui H, Divakaran A, Hoell ZJ, Ellingson MO, Scholtz CR, Zahid H, Johnson JA, Griffith EC, Gee CT, Lee AL, Khanal S, Shi K, Aihara H, Shah VH, Lee RE, Harki DA, Pomerantz WCK. A Structure-based Design Approach for Generating High Affinity BRD4 D1-Selective Chemical Probes. J Med Chem. 2022 Feb 10; 65 (3):2342-2360 Epub 2022 Jan 10
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  53. Sun L, Wang Y, Wang X, Navarro-Corcuera A, Ilyas S, Jalan-Sakrikar N, Gan C, Tu X, Shi Y, Tu K, Liu Q, Lou Z, Dong H, Sharpe AH, Shah VH, Kang N. PD-L1 promotes myofibroblastic activation of hepatic stellate cells by distinct mechanisms selective for TGF-beta receptor I versus II. Cell Rep. 2022 Feb 8; 38 (6):110349
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  54. Madathanapalli A, Tang Q, Lammert C, Samala N, Shah VH, Sanyal A, Chalasani N, Desai A. Health-related quality of life is dynamic in alcoholic hepatitis and responds to improvement in liver disease and reduced alcohol consumption. Alcohol Clin Exp Res. 2022 Feb; 46 (2):252-261 Epub 2021 Dec 16
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  55. Choi C, Choi DH, Spears GM, Peeraphatdit TB, Serafim LP, Gajic O, Kamath PS, Shah VH, Gallo de Moraes A, Simonetto DA. Relationship Between Etiology of Cirrhosis and Survival Among Patients Hospitalized in Intensive Care Units. Mayo Clin Proc. 2022 Feb; 97 (2):274-284 Epub 2022 Jan 25
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  56. Morales-Arraez D, Ventura-Cots M, Altamirano J, Abraldes JG, Cruz-Lemini M, Thursz MR, Atkinson SR, Sarin SK, Kim W, Chavez-Araujo R, Higuera-de la Tijera MF, Singal AK, Shah VH, Kamath PS, Duarte-Rojo A, Charles EA, Vargas V, Jager M, Rautou PE, Rincon D, Zamarripa F, Restrepo-Gutierrez JC, Torre A, Lucey MR, Arab JP, Mathurin P, Louvet A, Garcia-Tsao G, Gonzalez JA, Verna EC, Brown RS Jr, Argemi J, Fernandez-Carrillo C, Clemente A, Alvarado-Tapias E, Forrest E, Allison M, Bataller R. The MELD Score Is Superior to the Maddrey Discriminant Function Score to Predict Short-Term Mortality in Alcohol-Associated Hepatitis: A Global Study. Am J Gastroenterol. 2022 Feb 1; 117 (2):301-310
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  57. Kostallari E, Wei B, Sicard D, Li J, Cooper SA, Gao J, Dehankar M, Li Y, Cao S, Yin M, Tschumperlin DJ, Shah VH. Stiffness is associated with hepatic stellate cell heterogeneity during liver fibrosis. Am J Physiol Gastrointest Liver Physiol. 2022 Feb 1; 322 (2):G234-G246 Epub 2021 Dec 23
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  58. Jalan-Sakrikar N, De Assuncao TM, Navarro-Corcuera A, Hamdan FH, Loarca L, Kirkeby LA, Resch ZT, O'Hara SP, Juran BD, Lazaridis KN, Rosen CB, Heimbach JK, Taner T, Shah VH, LaRusso NF, Huebert RC. Induced Pluripotent Stem Cells From Subjects With Primary Sclerosing Cholangitis Develop a Senescence Phenotype Following Biliary Differentiation. Hepatol Commun. 2022 Feb; 6 (2):345-360 Epub 2021 Aug 25
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  59. Rattan P, Penrice DD, Ahn JC, Ferrer A, Patnaik M, Shah VH, Kamath PS, Mangaonkar AA, Simonetto DA. Inverse Association of Telomere Length With Liver Disease and Mortality in the US Population. Hepatol Commun. 2022 Feb; 6 (2):399-410 Epub 2021 Aug 28
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  60. Jones BE, Allegretti AS, Pose E, Mara KC, Ufere NN, Avitabile E, Shah VH, Kamath PS, Gines P, Simonetto DA. Renal Replacement Therapy for Acute Kidney Injury in Severe Alcohol-Associated Hepatitis as a Bridge to Transplant or Recovery. Dig Dis Sci. 2022 Feb; 67 (2):697-707 Epub 2021 Feb 19
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  61. Trebicka J, Louvet A, Arroyo V, Jalan R, Shah VH, Moreau R. Severe alcoholic hepatitis as precipitant for organ failure and ACLF. Z Gastroenterol. 2022 Jan; 60 (1):67-76 Epub 2022 Jan 18
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  62. Arab JP, Izzy M, Leggio L, Bataller R, Shah VH. Management of alcohol use disorder in patients with cirrhosis in the setting of liver transplantation. Nat Rev Gastroenterol Hepatol. 2022 Jan; 19 (1):45-59 Epub 2021 Nov 01
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  63. Ramkissoon R, Shah VH. Alcohol Use Disorder and Alcohol-Associated Liver Disease. Alcohol Res. 2022; 42 (1):13 Epub 2022 Nov 10
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  64. Kezer CA, Shah VH, Simonetto DA. Advances in Predictive Modeling Using Machine Learning in the Field of Hepatology. Clin Liver Dis (Hoboken). 2021 Dec; 18 (6):288-291 Epub 2021 Dec 20
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  65. Penrice DD, Shah S, Kezer CA, Peeraphatdit TB, Sanyal AJ, Davis B, Mara KC, Shah VH, Kamath PS, Simonetto DA. Risk Prediction of Nosocomial and Posthospital Discharge Infections in Alcohol-Associated Hepatitis. Hepatol Commun. 2021 Dec; 5 (12):2096-2103 Epub 2021 July 28
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  66. Im GY, Mellinger JL, Winters A, Aby ES, Lominadze Z, Rice J, Lucey MR, Arab JP, Goel A, Jophlin LL, Sherman CB, Parker R, Chen PH, Devuni D, Sidhu S, Dunn W, Szabo G, Singal AK, Shah VH. Provider Attitudes and Practices for Alcohol Screening, Treatment, and Education in Patients With Liver Disease: A Survey From the American Association for the Study of Liver Diseases Alcohol-Associated Liver Disease Special Interest Group. Clin Gastroenterol Hepatol. 2021 Nov; 19 (11):2407-2416.e8 Epub 2020 Oct 16
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  67. Arab JP, Diaz LA, Baeza N, Idalsoaga F, Fuentes-Lopez E, Arnold J, Ramirez CA, Morales-Arraez D, Ventura-Cots M, Alvarado-Tapias E, Zhang W, Clark V, Simonetto D, Ahn JC, Buryska S, Mehta TI, Stefanescu H, Horhat A, Bumbu A, Dunn W, Attar B, Agrawal R, Haque ZS, Majeed M, Cabezas J, Garcia-Carrera I, Parker R, Cuyas B, Poca M, Soriano G, Sarin SK, Maiwall R, Jalal PK, Abdulsada S, Higuera-de la Tijera MF, Kulkarni AV, Rao PN, Guerra Salazar P, Skladany L, Bystrianska N, Prado V, Clemente-Sanchez A, Rincon D, Haider T, Chacko KR, Cairo F, de Sousa Coelho M, Romero GA, Pollarsky FD, Restrepo JC, Castro-Sanchez S, Toro LG, Yaquich P, Mendizabal M, Garrido ML, Narvaez A, Bessone F, Marcelo JS, Piombino D, Dirchwolf M, Arancibia JP, Altamirano J, Kim W, Araujo RC, Duarte-Rojo A, Vargas V, Rautou PE, Issoufaly T, Zamarripa F, Torre A, Lucey MR, Mathurin P, Louvet A, Garcia-Tsao G, Gonzalez JA, Verna E, Brown RS, Roblero JP, Abraldes JG, Arrese M, Shah VH, Kamath PS, Singal AK, Bataller R. Identification of optimal therapeutic window for steroid use in severe alcohol-associated hepatitis: A worldwide study. J Hepatol. 2021 Nov; 75 (5):1026-1033 Epub 2021 June 21
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  69. Chen J, Martin-Mateos R, Li J, Yin Z, Chen J, Lu X, Glaser KJ, Mounajjed T, Yashiro H, Siegelman J, Winkelmann CT, Wang J, Ehman RL, Shah VH, Yin M. Multiparametric magnetic resonance imaging/magnetic resonance elastography assesses progression and regression of steatosis, inflammation, and fibrosis in alcohol-associated liver disease. Alcohol Clin Exp Res. 2021 Oct; 45 (10):2103-2117 Epub 2021 Sept 05
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  71. Shamseddeen H, Madathanapalli A, Are VS, Shah VH, Sanyal AJ, Tang Q, Liang T, Gelow K, Zimmers TA, Chalasani N, Desai AP. Changes in Serum Myostatin Levels in Alcoholic Hepatitis Correlate with Improvement in MELD. Dig Dis Sci. 2021 Sep; 66 (9):3062-3073 Epub 2020 Oct 19
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  72. Cao S, Liu M, Sehrawat TS, Shah VH. Regulation and functional roles of chemokines in liver diseases. Nat Rev Gastroenterol Hepatol. 2021 Sep; 18 (9):630-647 Epub 2021 May 11
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  73. Kostallari E, Valainathan S, Biquard L, Shah VH, Rautou PE. Role of extracellular vesicles in liver diseases and their therapeutic potential. Adv Drug Deliv Rev. 2021 Aug; 175:113816 Epub 2021 June 02
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  75. Liu M, Cao S, He L, Gao J, Arab JP, Cui H, Xuan W, Gao Y, Sehrawat TS, Hamdan FH, Ventura-Cots M, Argemi J, Pomerantz WCK, Johnsen SA, Lee JH, Gao F, Ordog T, Mathurin P, Revzin A, Bataller R, Yan H, Shah VH. Super enhancer regulation of cytokine-induced chemokine production in alcoholic hepatitis. Nat Commun. 2021 Jul 27; 12 (1):4560 Epub 2021 July 27
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  76. Shah V, Iwakiri Y, Boyer JL. Obituary for Roberto J. Groszmann - the Father of Portal Hypertension. Hepatology. 2021 Jun 9 Epub 2021 June 09
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  77. Ahn JC, Connell A, Simonetto DA, Hughes C, Shah VH. Application of Artificial Intelligence for the Diagnosis and Treatment of Liver Diseases. Hepatology. 2021 Jun; 73 (6):2546-2563
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  78. Gao J, Wei B, Liu M, Hirsova P, Sehrawat TS, Cao S, Hu X, Xue F, Yaqoob U, Kang N, Cui H, Pomerantz WCK, Kostallari E, Shah VH. Endothelial p300 Promotes Portal Hypertension and Hepatic Fibrosis Through C-C Motif Chemokine Ligand 2-Mediated Angiocrine Signaling. Hepatology. 2021 Jun; 73 (6):2468-2483 Epub 2021 Apr 19
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  79. Asrani SK, Mellinger J, Arab JP, Shah VH. Reducing the Global Burden of Alcohol-Associated Liver Disease: A Blueprint for Action. Hepatology. 2021 May; 73 (5):2039-2050
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  80. Xue F, Lu J, Buchl SC, Sun L, Shah VH, Malhi H, Maiers JL. Coordinated signaling of activating transcription factor 6alpha and inositol-requiring enzyme 1alpha regulates hepatic stellate cell-mediated fibrogenesis in mice. Am J Physiol Gastrointest Liver Physiol. 2021 May 1; 320 (5):G864-G879 Epub 2021 Mar 17
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  81. Beaudoin JJ, Liang T, Tang Q, Banini BA, Shah VH, Sanyal AJ, Chalasani NP, Gawrieh S. Role of candidate gene variants in modulating the risk and severity of alcoholic hepatitis. Alcohol Clin Exp Res. 2021 Apr; 45 (4):709-719 Epub 2021 Apr 20
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  82. Massey V, Parrish A, Argemi J, Moreno M, Mello A, Garcia-Rocha M, Altamirano J, Odena G, Dubuquoy L, Louvet A, Martinez C, Adrover A, Affo S, Morales-Ibanez O, Sancho-Bru P, Millan C, Alvarado-Tapias E, Morales-Arraez D, Caballeria J, Mann J, Cao S, Sun Z, Shah V, Cameron A, Mathurin P, Snider N, Villanueva C, Morgan TR, Guinovart J, Vadigepalli R, Bataller R. Integrated Multiomics Reveals Glucose Use Reprogramming and Identifies a Novel Hexokinase in Alcoholic Hepatitis. Gastroenterology. 2021 Apr; 160 (5):1725-1740.e2 Epub 2020 Dec 10
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  83. Yohanathan L, Corsini CG, Ramkissoon R, Mousa O, Watt KD, Friedman DZP, Shah VH, Hines AS, Kamath PS, Razonable RR, Badley AD, DeMartino ES, Joyner MJ, Vergidis P, Simonetto DA, Sanchez W, Taner T, Heimbach JK, Beam E, Leise MD. Liver Transplantation for Acute Liver Failure in a Patient with COVID-19 Infection and SARS-CoV-2 PCR Positivity American Journal of Transplantation. 2021.
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  85. Yang J, Syed F, Xia Y, Sanyal AJ, Shah VH, Chalasani N, Zheng X, Yu Q, Lou Y, Li W. Blood Biomarkers of Intestinal Epithelium Damage Regenerating Islet-derived Protein 3alpha and Trefoil Factor 3 Are Persistently Elevated in Patients with Alcoholic Hepatitis. Alcohol Clin Exp Res. 2021 Apr; 45 (4):720-731 Epub 2021 Mar 11
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  86. Li J, Sehrawat TS, Chen J, Hilscher MB, Glaser KJ, Arab JP, De Assuncao TM, Simonetto DA, Mounajjed T, Manduca A, Ehman RL, Shah VH, Yin M. Quantitative assessment of portal hypertension with bi-parametric dual-frequency hepatic MR elastography in mouse models. Eur Radiol. 2021 Apr; 31 (4):2303-2311 Epub 2020 Oct 07
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  87. Furuta K, Guo Q, Pavelko KD, Lee JH, Robertson KD, Nakao Y, Melek J, Shah VH, Hirsova P, Ibrahim SH. Lipid-induced endothelial vascular cell adhesion molecule 1 promotes nonalcoholic steatohepatitis pathogenesis. J Clin Invest. 2021 Mar 15; 131 (6)
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  88. Guldiken N, Argemi J, Gurbuz B, Atkinson SR, Oliverius M, Fila P, Hamesch K, Bruns T, Cabezas J, Lozano JJ, Mann J, Cao S, Mathurin P, Shah VH, Trautwein C, Thursz MR, Bataller R, Strnad P. Serum transferrin as a biomarker of hepatocyte nuclear factor 4 alpha activity and hepatocyte function in liver diseases. BMC Med. 2021 Feb 17; 19 (1):39
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  90. Ahn JC, Shah VH. Deep learning-based detection of hepatobiliary disorders in ophthalmic imaging. Lancet Digit Health 2021 Feb; 3 (2):e68-e69
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  91. Aseem SO, Jalan-Sakrikar N, Chi C, Navarro-Corcuera A, De Assuncao TM, Hamdan FH, Chowdhury S, Banales JM, Johnsen SA, Shah VH, Huebert RC. Epigenomic Evaluation of Cholangiocyte Transforming Growth Factor-beta Signaling Identifies a Selective Role for Histone 3 Lysine 9 Acetylation in Biliary Fibrosis. Gastroenterology. 2021 Feb; 160 (3):889-905.e10 Epub 2020 Oct 12
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  92. He L, Sehrawat TS, Verma VK, Navarro-Corcuera A, Sidhu G, Mauer A, Luo X, Katsumi T, Chen J, Shah S, Arab JP, Cao S, Kashkar H, Gores GJ, Malhi H, Shah VH. XIAP Knockdown in Alcohol-Associated Liver Disease Models Exhibits Divergent in vitro and in vivo Phenotypes Owing to a Potential Zonal Inhibitory Role of SMAC. Front Physiol. 2021; 12:664222 Epub 2021 May 07
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  93. Peeraphatdit TB, Ahn JC, Choi DH, Allen AM, Simonetto DA, Kamath PS, Shah VH. A Cohort Study Examining the Interaction of Alcohol Consumption and Obesity in Hepatic Steatosis and Mortality. Mayo Clin Proc. 2020 Dec; 95 (12):2612-2620
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  94. Gao J, Wei B, de Assuncao TM, Liu Z, Hu X, Ibrahim S, Cooper SA, Cao S, Shah VH, Kostallari E. Hepatic stellate cell autophagy inhibits extracellular vesicle release to attenuate liver fibrosis. J Hepatol. 2020 Nov; 73 (5):1144-1154 Epub 2020 May 08
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  95. Peeraphatdit TB, Nkomo VT, Naksuk N, Simonetto DA, Thakral N, Spears GM, Harmsen WS, Shah VH, Greason KL, Kamath PS. Long-Term Outcomes After Transcatheter and Surgical Aortic Valve Replacement in Patients With Cirrhosis: A Guide for the Hepatologist. Hepatology. 2020 Nov; 72 (5):1735-1746 Epub 2020 Oct 15
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  96. Choi JH, Loarca L, De Hoyos-Vega JM, Dadgar N, Loutherback K, Shah VH, Stybayeva G, Revzin A. Microfluidic confinement enhances phenotype and function of hepatocyte spheroids. Am J Physiol Cell Physiol. 2020 Sep 1; 319 (3):C552-C560 Epub 2020 July 22
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  97. Xiang X, Hwang S, Feng D, Shah VH, Gao B. Interleukin-22 in alcoholic hepatitis and beyond. Hepatol Int. 2020 Sep; 14 (5):667-676 Epub 2020 Sept 05
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  98. Smirnova E, Puri P, Muthiah MD, Daitya K, Brown R, Chalasani N, Liangpunsakul S, Shah VH, Gelow K, Siddiqui MS, Boyett S, Mirshahi F, Sikaroodi M, Gillevet P, Sanyal AJ. Fecal Microbiome Distinguishes Alcohol Consumption From Alcoholic Hepatitis But Does Not Discriminate Disease Severity. Hepatology. 2020 Jul; 72 (1):271-286
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  100. Xia Y, Yang J, Sanyal AJ, Shah VH, Chalasani NP, Yu Q, Zheng X, Li W. Persistent Hyperactivation of Endothelial Cells in Patients with Alcoholic Hepatitis. Alcohol Clin Exp Res. 2020 May; 44 (5):1075-1087 Epub 2020 Apr 21
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  101. Simonetto DA, Shah VH, Kamath PS. Outpatient management of alcohol-related liver disease. Lancet Gastroenterol Hepatol. 2020 May; 5 (5):485-493
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  102. Sehrawat TS, Liu M, Shah VH. The knowns and unknowns of treatment for alcoholic hepatitis. Lancet Gastroenterol Hepatol. 2020 May; 5 (5):494-506
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  103. Faulkner CS, White CM, Shah VH, Jophlin LL. A single nucleotide polymorphism of PLIN2 is associated with nonalcoholic steatohepatitis and causes phenotypic changes in hepatocyte lipid droplets: A pilot study. Biochim Biophys Acta Mol Cell Biol Lipids. 2020 May; 1865 (5):158637 Epub 2020 Jan 23
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  104. Jophlin LL, Cao S, Shah VH. The Transcriptome of Hepatic Fibrosis Revealed by Single-Cell RNA Sequencing. Hepatology 2020 May; 71 (5):1865-1867
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  105. Hilscher MB, Shah VH. Neutrophil Extracellular Traps and Liver Disease. Semin Liver Dis. 2020 May; 40 (2):171-179 Epub 2019 Nov 14
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  106. Li W, Xia Y, Yang J, Guo H, Sun G, Sanyal AJ, Shah VH, Lou Y, Zheng X, Chalasani N, Yu Q. Immune Checkpoint Axes Are Dysregulated in Patients With Alcoholic Hepatitis. Hepatol Commun. 2020 Apr; 4 (4):588-605 Epub 2020 Jan 12
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  107. Arab JP, Arrese M, Shah VH. Gut microbiota in non-alcoholic fatty liver disease and alcohol-related liver disease: Current concepts and perspectives. Hepatol Res. 2020 Apr; 50 (4):407-418 Epub 2020 Jan 13
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  108. Xiang X, Feng D, Hwang S, Ren T, Wang X, Trojnar E, Matyas C, Mo R, Shang D, He Y, Seo W, Shah VH, Pacher P, Xie Q, Gao B. Interleukin-22 ameliorates acute-on-chronic liver failure by reprogramming impaired regeneration pathways in mice. J Hepatol. 2020 Apr; 72 (4):736-745 Epub 2019 Nov 29
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  109. Hilscher MB, Shah VH. Small but Mighty: Platelets in NASH and Other Chronic Liver Diseases. Hepatology 2020 Apr; 71 (4):1501-1504 Epub 2020 Mar 18
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  110. Shaheen MF, Joo DJ, Ross JJ, Anderson BD, Chen HS, Huebert RC, Li Y, Amiot B, Young A, Zlochiver V, Nelson E, Mounajjed T, Dietz AB, Michalak G, Steiner BG, Davidow DS, Paradise CR, van Wijnen AJ, Shah VH, Liu M, Nyberg SL. Author Correction: Sustained perfusion of revascularized bioengineered livers heterotopically transplanted into immunosuppressed pigs. Nat Biomed Eng. 2020 Apr; 4 (4):476
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  111. Shaheen MF, Joo D, Ross JJ, Anderson BD, Chen HS, Huebert RC, Li Y, Amiot B, Young A, Zlochiver V, Nelson E, Mounajjed T, Dietz AB, Michalak G, Steiner BG, Davidow DS, Paradise CR, van Wijnen AJ, Shah VH, Liu M, Nyberg SL. Sustained perfusion of revascularized bioengineered livers heterotopically transplanted into immunosuppressed pigs. Nat Biomed Eng. 2020 Apr; 4 (4):437-445 Epub 2019 Oct 14
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  112. Atkinson SR, Hamesch K, Spivak I, Guldiken N, Cabezas J, Argemi J, Theurl I, Zoller H, Cao S, Mathurin P, Shah VH, Trautwein C, Bataller R, Thursz MR, Strnad P. Serum Transferrin Is an Independent Predictor of Mortality in Severe Alcoholic Hepatitis. Am J Gastroenterol. 2020 Mar; 115 (3):398-405
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  113. Peeraphatdit TB, Kamath PS, Karpyak VM, Davis B, Desai V, Liangpunsakul S, Sanyal A, Chalasani N, Shah VH, Simonetto DA. Alcohol Rehabilitation Within 30 Days of Hospital Discharge Is Associated With Reduced Readmission, Relapse, and Death in Patients With Alcoholic Hepatitis. Clin Gastroenterol Hepatol. 2020 Feb; 18 (2):477-485.e5 Epub 2019 Apr 28
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  114. Allen AM, Shah VH, Therneau TM, Venkatesh SK, Mounajjed T, Larson JJ, Mara KC, Schulte PJ, Kellogg TA, Kendrick ML, McKenzie TJ, Greiner SM, Li J, Glaser KJ, Wells ML, Chen J, Ehman RL, Yin M. The Role of Three-Dimensional Magnetic Resonance Elastography in the Diagnosis of Nonalcoholic Steatohepatitis in Obese Patients Undergoing Bariatric Surgery. Hepatology. 2020 Feb; 71 (2):510-521 Epub 2019 Mar 15
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  115. Allen AM, Shah VH, Therneau TM, Venkatesh SK, Mounajjed T, Larson JJ, Mara KC, Kellogg TA, Kendrick ML, McKenzie TJ, Greiner SM, Li J, Glaser KJ, Wells ML, Gunneson TJ, Ehman RL, Yin M. Multiparametric Magnetic Resonance Elastography Improves the Detection of NASH Regression Following Bariatric Surgery. Hepatol Commun. 2020 Feb; 4 (2):185-192 Epub 2019 Nov 05
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  116. Maddur H, Shah VH. Alcohol and Liver Function in Women. Alcohol Res. 2020; 40 (2):10 Epub 2020 July 02
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  117. Yaqoob U, Luo F, Greuter T, Jalan Sakrikar N, Sehrawat TS, Lu J, Hu X, Gao J, Kostallari E, Chen J, Arab JP, Martin-Mateos R, Cao S, Shah VH. GIPC-Regulated IGFBP-3 Promotes HSC Migration In Vitro and Portal Hypertension In Vivo Through a beta1-Integrin Pathway. Cell Mol Gastroenterol Hepatol. 2020; 10 (3):545-559 Epub 2020 May 22
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  118. Asrani SK, Trotter J, Lake J, Ahmed A, Bonagura A, Cameron A, DiMartini A, Gonzalez S, Im G, Martin P, Mathurin P, Mellinger J, Rice JP, Shah VH, Terrault N, Wall A, Winder S, Klintmalm G. Meeting Report: The Dallas Consensus Conference on Liver Transplantation for Alcohol Associated Hepatitis. Liver Transpl. 2020 Jan; 26 (1):127-140
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  119. Robinson KE, Shah VH. Pathogenesis and pathways: nonalcoholic fatty liver disease & alcoholic liver disease. Transl Gastroenterol Hepatol. 2020; 5:49 Epub 2020 Oct 05
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  120. Cao Q, Sun X, Rajesh K, Chalasani N, Gelow K, Katz B, Shah VH, Sanyal AJ, Smirnova E. Effects of Rare Microbiome Taxa Filtering on Statistical Analysis. Front Microbiol. 2020; 11:607325 Epub 2021 Jan 12
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  121. Singal AK, Arora S, Wong RJ, Satapathy SK, Shah VH, Kuo YF, Kamath PS. Increasing Burden of Acute-On-Chronic Liver Failure Among Alcohol-Associated Liver Disease in the Young Population in the United States. Am J Gastroenterol. 2020 Jan; 115 (1):88-95
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  122. Maddur H, Shah VH. The role of nutrition in the pathogenesis and treatment of alcohol-related liver disease. Current Hepatology Reports. 2020; 19 (1):7-12
  123. Mindikoglu AL, Coarfa C, Opekun AR, Shah VH, Arab JP, Lazaridis KN, Putluri N, Ambati CR, Robertson MJ, Devaraj S, Jalal PK, Rana A, Goss JA, Dowling TC, Weir MR, Seliger SL, Raufman JP, Bernard DW, Vierling JM. Metabolomic biomarkers are associated with mortality in patients with cirrhosis caused by primary biliary cholangitis or primary sclerosing cholangitis. Future Sci OA. 2019 Dec 17; 6 (2):FSO441
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  124. Garg SK, Sarvepalli S, Singh D, Obaitan I, Peeraphatdit T, Jophlin L, Asrani SK, Shah VH, Leise MD. Incidence and Risk Factors Associated With 30-Day Readmission for Alcoholic Hepatitis. J Clin Gastroenterol. 2019 Nov/Dec; 53 (10):759-764
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  125. Jalan-Sakrikar N, De Assuncao TM, Shi G, Aseem S, Chi C, Shah VH, Huebert RC. Proteasomal Degradation of Enhancer of Zeste Homologue 2 in Cholangiocytes Promotes Biliary Fibrosis. Hepatology. 2019 Nov; 70 (5):1674-1689 Epub 2019 June 22
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  126. Haak AJ, Kostallari E, Sicard D, Ligresti G, Choi KM, Caporarello N, Jones DL, Tan Q, Meridew J, Diaz Espinosa AM, Aravamudhan A, Maiers JL, Britt RD Jr, Roden AC, Pabelick CM, Prakash YS, Nouraie SM, Li X, Zhang Y, Kass DJ, Lagares D, Tager AM, Varelas X, Shah VH, Tschumperlin DJ. Selective YAP/TAZ inhibition in fibroblasts via dopamine receptor D1 agonism reverses fibrosis. Sci Transl Med. 2019 Oct 30; 11 (516)
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  127. Wang Y, Tu K, Liu D, Guo L, Chen Y, Li Q, Maiers JL, Liu Z, Shah VH, Dou C, Tschumperlin D, Voneschen L, Yang R, Kang N. p300 Acetyltransferase Is a Cytoplasm-to-Nucleus Shuttle for SMAD2/3 and TAZ Nuclear Transport in Transforming Growth Factor beta-Stimulated Hepatic Stellate Cells. Hepatology. 2019 Oct; 70 (4):1409-1423 Epub 2019 May 23
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  128. Shah VH, Shah PP. How to Use Emotional Intelligence as a Career Catalyst- the X-Factor of Success for Trainees and Faculty in Gastroenterology and Hepatology. Gastroenterology. 2019 Aug; 157 (2):289-292 Epub 2019 May 11
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  129. Sunjaya DB, Lennon RJ, Shah VH, Kamath PS, Simonetto DA. Prevalence and Predictors of Third-Generation Cephalosporin Resistance in the Empirical Treatment of Spontaneous Bacterial Peritonitis. Mayo Clin Proc. 2019 Aug; 94 (8):1499-1508 Epub 2019 July 11
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  132. Samala N, Gawrieh S, Tang Q, Lourens SG, Shah VH, Sanyal AJ, Liangpunsakul S, Chalasani N. Clinical Characteristics and Outcomes of Mild to Moderate Alcoholic Hepatitis. GastroHep. 2019 Jul; 1 (4):161-165 Epub 2019 June 14
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  134. Li W, Lin EL, Liangpunsakul S, Lan J, Chalasani S, Rane S, Puri P, Kamath PS, Sanyal AJ, Shah VH, Radaeva S, Crabb DW, Chalasani N, Yu Q. Alcohol Abstinence Does Not Fully Reverse Abnormalities of Mucosal-Associated Invariant T Cells in the Blood of Patients With Alcoholic Hepatitis. Clin Transl Gastroenterol. 2019 Jun; 10 (6):e00052
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  135. Szabo G, Kamath PS, Shah VH, Thursz M, Mathurin P, EASL-AASLD Joint Meeting. Alcohol-Related Liver Disease: Areas of Consensus, Unmet Needs and Opportunities for Further Study. Hepatology. 2019 May; 69 (5):2271-2283 Epub 2019 Jan 15
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  137. Wang L, Feng Y, Xie X, Wu H, Su XN, Qi J, Xin W, Gao L, Zhang Y, Shah VH, Zhu Q. Neuropilin-1 aggravates liver cirrhosis by promoting angiogenesis via VEGFR2-dependent PI3K/Akt pathway in hepatic sinusoidal endothelial cells. EBioMedicine. 2019 May; 43:525-536 Epub 2019 May 03
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  138. Liu M, Shah VH. New Prospects for Medical Management of Acute Alcoholic Hepatitis. Clin Liver Dis (Hoboken). 2019 May; 13 (5):131-135 Epub 2019 May 31
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  139. Sharma M, Singh S, Desai V, Shah VH, Kamath PS, Murad MH, Simonetto DA. Comparison of Therapies for Primary Prevention of Esophageal Variceal Bleeding: A Systematic Review and Network Meta-analysis. Hepatology. 2019 Apr; 69 (4):1657-1675 Epub 2019 Feb 20
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  140. Thursz M, Kamath PS, Mathurin P, Szabo G, Shah VH. Alcohol-related liver disease: Areas of consensus, unmet needs and opportunities for further study. J Hepatol. 2019 Mar; 70 (3):521-530 Epub 2019 Jan 15
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  141. Liu Z, Li C, Kang N, Malhi H, Shah VH, Maiers JL. Transforming growth factor beta (TGFbeta) cross-talk with the unfolded protein response is critical for hepatic stellate cell activation. J Biol Chem. 2019 Mar 1; 294 (9):3137-3151 Epub 2019 Jan 04
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  142. Abraldes JG, Trebicka J, Chalasani N, D'Amico G, Rockey DC, Shah VH, Bosch J, Garcia-Tsao G. Prioritization of Therapeutic Targets and Trial Design in Cirrhotic Portal Hypertension. Hepatology. 2019 Mar; 69 (3):1287-1299 Epub 2019 Feb 09
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  144. Singal AK, Bataller R, Ahn J, Kamath PS, Shah VH. Response to Forrest et al. Am J Gastroenterol 2019 Jan; 114 (1):176
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  145. Martin-Mateos R, De Assuncao TM, Arab JP, Jalan-Sakrikar N, Yaqoob U, Greuter T, Verma VK, Mathison AJ, Cao S, Lomberk G, Mathurin P, Urrutia R, Huebert RC, Shah VH. Enhancer of Zeste Homologue 2 Inhibition Attenuates TGF-beta Dependent Hepatic Stellate Cell Activation and Liver Fibrosis. Cell Mol Gastroenterol Hepatol. 2019; 7 (1):197-209 Epub 2018 Sept 15
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  146. Greuter T, Shah VH. Too Stiff, Too Late . . . Timing Is Everything in Antiangiogenic Treatment of Liver Fibrosis. Hepatology. 2019 Jan; 69 (1):449-451 Epub 2018 Dec 18
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  147. Kamath PS, Shah VH. Alcohol-related Liver Disease: Areas of Consensus, Unmet Needs and Opportunities for Further Study. Hepatology. 2018 Dec 18 [Epub ahead of print]
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  148. Sujan R, Cruz-Lemini M, Altamirano J, Simonetto DA, Maiwall R, Axley P, Richardson T, Desai V, Cabezas J, Vargas V, Kamath PS, Shah VH, Sarin SK, Bataller R, Singal AK. A Validated Score Predicts Acute Kidney Injury and Survival in Patients With Alcoholic Hepatitis. Liver Transpl. 2018 Dec; 24 (12):1655-1664
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  149. Jophlin LL, Koutalos Y, Chen C, Shah V, Rockey DC. Hepatic stellate cells retain retinoid-laden lipid droplets after cellular transdifferentiation into activated myofibroblasts. Am J Physiol Gastrointest Liver Physiol. 2018 Nov 1; 315 (5):G713-G721 Epub 2018 July 19
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  150. Samala N, Lourens SG, Shah VH, Kamath PS, Sanyal AJ, Crabb DW, Tang Q, Radaeva S, Liangpunsakul S, Chalasani N. Posttraumatic Stress Disorder in Patients with Heavy Alcohol Consumption and Alcoholic Hepatitis. Alcohol Clin Exp Res. 2018 Oct; 42 (10):1933-1938 Epub 2018 Aug 26
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  151. Singal AK, Louvet A, Shah VH, Kamath PS. Grand Rounds: Alcoholic Hepatitis. J Hepatol. 2018 Aug; 69 (2):534-543 Epub 2018 June 13
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  152. Kolla BP, Schneekloth TD, Biernacka J, Shah V, Lazaridis KN, Geske J, Karpyak V. PNPLA3 Association with Alcoholic Liver Disease in a Cohort of Heavy Drinkers. Alcohol Alcohol. 2018 Jul 1; 53 (4):357-360
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  153. Kostallari E, Hirsova P, Prasnicka A, Verma VK, Yaqoob U, Wongjarupong N, Roberts LR, Shah VH. Hepatic stellate cell-derived platelet-derived growth factor receptor-alpha-enriched extracellular vesicles promote liver fibrosis in mice through SHP2. Hepatology. 2018 Jul; 68 (1):333-348 Epub 2018 May 10
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  154. Dou C, Liu Z, Tu K, Zhang H, Chen C, Yaqoob U, Wang Y, Wen J, van Deursen J, Sicard D, Tschumperlin D, Zou H, Huang WC, Urrutia R, Shah VH, Kang N. P300 Acetyltransferase Mediates Stiffness-Induced Activation of Hepatic Stellate Cells Into Tumor-Promoting Myofibroblasts. Gastroenterology. 2018 Jun; 154 (8):2209-2221.e14 Epub 2018 Feb 15
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  155. Sunjaya DB, Ramos GP, Braga Neto MB, Lennon R, Mounajjed T, Shah V, Kamath PS, Simonetto DA. Isolated hepatic non-obstructive sinusoidal dilatation, 20-year single center experience. World J Hepatol. 2018 May 27; 10 (5):417-424
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  156. Puri P, Liangpunsakul S, Christensen JE, Shah VH, Kamath PS, Gores GJ, Walker S, Comerford M, Katz B, Borst A, Yu Q, Kumar DP, Mirshahi F, Radaeva S, Chalasani NP, Crabb DW, Sanyal AJ, TREAT Consortium. The circulating microbiome signature and inferred functional metagenomics in alcoholic hepatitis. Hepatology. 2018 Apr; 67 (4):1284-1302 Epub 2018 Feb 22
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  157. Chirapongsathorn S, Krittanawong C, Enders FT, Pendegraft R, Mara KC, Borah BJ, Visscher SL, Loftus CG, Shah VH, Talwalkar JA, Kamath PS. Incidence and cost analysis of hospital admission and 30-day readmission among patients with cirrhosis. Hepatol Commun. 2018 Feb; 2 (2):188-198 Epub 2018 Jan 18
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  158. Singal AK, Bataller R, Ahn J, Kamath PS, Shah VH. ACG Clinical Guideline: Alcoholic Liver Disease. Am J Gastroenterol. 2018 Feb; 113 (2):175-194 Epub 2018 Jan 16
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  159. Sherman KE, Shah VH. Viral Hepatitis: Knowledge and Treatments for Hepatitis B and C Virus and Associated Transplantation and Neoplasia. Gastroenterology. 2018 Feb; 154 (3):453-456 Epub 2017 Nov 14
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  160. Arab JP, Martin-Mateos RM, Shah VH. Gut-liver axis, cirrhosis and portal hypertension: the chicken and the egg. Hepatol Int. 2018 Feb; 12 (Suppl 1):24-33 Epub 2017 May 26
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  161. Tschumperlin DJ, Ligresti G, Hilscher MB, Shah VH. Mechanosensing and fibrosis. J Clin Invest. 2018 Jan 2; 128 (1):74-84 Epub 2018 Jan 02
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  162. Liangpunsakul S, Beaudoin JJ, Shah VH, Puri P, Sanyal AJ, Kamath PS, Lourens SG, Tang Q, Katz BP, Crabb DW, Chalasani NP. Interaction between the patatin-like phospholipase domain-containing protein 3 genotype and coffee drinking and the risk for acute alcoholic hepatitis. Hepatol Commun. 2018 Jan; 2 (1):29-34 Epub 2017 Nov 11
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  163. Drinane MC, Yaqoob U, Yu H, Luo F, Greuter T, Arab JP, Kostallari E, Verma VK, Maiers J, De Assuncao TM, Simons M, Mukhopadhyay D, Kisseleva T, Brenner DA, Urrutia R, Lomberk G, Gao Y, Ligresti G, Tschumperlin DJ, Revzin A, Cao S, Shah VH. Synectin promotes fibrogenesis by regulating PDGFR isoforms through distinct mechanisms. JCI Insight. 2017 Dec 21; 2 (24)
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  164. Comerford M, Lourens S, Liangpunsakul S, Chalasani NP, Sanyal AJ, Shah VH, Kamath PS, Puri P, Katz BP, Radaeva S, Crabb DW. Challenges in Patient Enrollment and Retention in Clinical Studies for Alcoholic Hepatitis: Experience of the TREAT Consortium. Alcohol Clin Exp Res. 2017 Dec; 41 (12):2000-2006 Epub 2017 Oct 27
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  165. Simonetto DA, Kamath PS, Shah VH. Alcoholic hepatitis: Continued drinking and the mourning after. Hepatology 2017 Nov; 66 (5):1370-1372 Epub 2017 Oct 11
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  166. Beaudoin JJ, Long N, Liangpunsakul S, Puri P, Kamath PS, Shah V, Sanyal AJ, Crabb DW, Chalasani NP, Urban TJ, TREAT Consortium. An exploratory genome-wide analysis of genetic risk for alcoholic hepatitis. Scand J Gastroenterol. 2017 Nov; 52 (11):1263-1269 Epub 2017 Aug 04
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  167. Greuter T, Malhi H, Gores GJ, Shah VH. Therapeutic opportunities for alcoholic steatohepatitis and nonalcoholic steatohepatitis: exploiting similarities and differences in pathogenesis. JCI Insight. 2017 Sep 7; 2 (17) Epub 2017 Sept 07
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  168. Liu Y, Verma VK, Malhi H, Gores GJ, Kamath PS, Sanyal A, Chalasani N, Gao B, Shah VH. Lipopolysaccharide downregulates macrophage-derived IL-22 to modulate alcohol-induced hepatocyte cell death. Am J Physiol Cell Physiol. 2017 Sep 1; 313 (3):C305-C313 Epub 2017 June 21
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  169. Vargas JI, Arrese M, Shah VH, Arab JP. Use of Statins in Patients with Chronic Liver Disease and Cirrhosis: Current Views and Prospects. Curr Gastroenterol Rep. 2017 Sep; 19 (9):43
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  170. Yin M, Glaser KJ, Manduca A, Mounajjed T, Malhi H, Simonetto DA, Wang R, Yang L, Mao SA, Glorioso JM, Elgilani FM, Ward CJ, Harris PC, Nyberg SL, Shah VH, Ehman RL. Distinguishing between Hepatic Inflammation and Fibrosis with MR Elastography. Radiology. 2017 Sep; 284 (3):694-705 Epub 2017 Jan 27
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  171. Li W, Amet T, Xing Y, Yang D, Liangpunsakul S, Puri P, Kamath PS, Sanyal AJ, Shah VH, Katz BP, Radaeva S, Crabb DW, Chalasani N, Yu Q. Alcohol abstinence ameliorates the dysregulated immune profiles in patients with alcoholic hepatitis: A prospective observational study. Hepatology. 2017 Aug; 66 (2):575-590 Epub 2017 June 30
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  172. Lourens S, Sunjaya DB, Singal A, Liangpunsakul S, Puri P, Sanyal A, Ren X, Gores GJ, Radaeva S, Chalasani N, Crabb DW, Katz B, Kamath PS, Shah VH, TREAT Consortium. Acute Alcoholic Hepatitis: Natural History and Predictors of Mortality Using a Multicenter Prospective Study. Mayo Clin Proc Innov Qual Outcomes. 2017 Jul; 1 (1):37-48 Epub 2017 Apr 28
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  173. Mauer AS, Hirsova P, Maiers JL, Shah VH, Malhi H. Inhibition of sphingosine 1-phosphate signaling ameliorates murine nonalcoholic steatohepatitis. Am J Physiol Gastrointest Liver Physiol. 2017 Mar 1; 312 (3):G300-G313 Epub 2016 Dec 30
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  174. Maiers JL, Kostallari E, Mushref M, deAssuncao TM, Li H, Jalan-Sakrikar N, Huebert RC, Cao S, Malhi H, Shah VH. The unfolded protein response mediates fibrogenesis and collagen I secretion through regulating TANGO1 in mice. Hepatology. 2017 Mar; 65 (3):983-998 Epub 2016 Dec 31
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  175. Chen G, Nakamura I, Dhanasekaran R, Iguchi E, Tolosa EJ, Romecin PA, Vera RE, Almada LL, Miamen AG, Chaiteerakij R, Zhou M, Asiedu MK, Moser CD, Han S, Hu C, Banini BA, Oseini AM, Chen Y, Fang Y, Yang D, Shaleh HM, Wang S, Wu D, Song T, Lee JS, Thorgeirsson SS, Chevet E, Shah VH, Fernandez-Zapico ME, Roberts LR. Transcriptional Induction of Periostin by a Sulfatase 2-TGFbeta1-SMAD Signaling Axis Mediates Tumor Angiogenesis in Hepatocellular Carcinoma. Cancer Res. 2017 Feb 1; 77 (3):632-645 Epub 2016 Nov 21
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  176. Wang R, Ding Q, De Assuncao TM, Mounajjed T, Maiers JL, Dou C, Cao S, Yaqoob U, Huebert RC, Shah VH. Hepatic Stellate Cell Selective Disruption of Dynamin-2 GTPase Increases Murine Fibrogenesis through Up-Regulation of Sphingosine-1 Phosphate-Induced Cell Migration. Am J Pathol. 2017 Jan; 187 (1):134-145 Epub 2016 Nov 10
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  177. Russ KB, Chen NW, Kamath PS, Shah VH, Kuo YF, Singal AK. Reply to ''Alcohol and Liver Transplantation''. Alcohol Alcohol. 2017 Jan; 52 (1):127 Epub 2016 Sept 05
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  178. Hirsova P, Ibrahim SH, Verma VK, Morton LA, Shah VH, LaRusso NF, Gores GJ, Malhi H. Extracellular vesicles in liver pathobiology: Small particles with big impact. Hepatology. 2016 Dec; 64 (6):2219-2233 Epub 2016 Oct 20
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  179. Liangpunsakul S, Puri P, Shah VH, Kamath P, Sanyal A, Urban T, Ren X, Katz B, Radaeva S, Chalasani N, Crabb DW, Translational Research and Evolving Alcoholic Hepatitis Treatment Consortium. Effects of Age, Sex, Body Weight, and Quantity of Alcohol Consumption on Occurrence and Severity of Alcoholic Hepatitis. Clin Gastroenterol Hepatol. 2016 Dec; 14 (12):1831-1838.e3 Epub 2016 June 15
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  180. Russ KB, Chen NW, Kamath PS, Shah VH, Kuo YF, Singal AK. Alcohol Use after Liver Transplantation is Independent of Liver Disease Etiology. Alcohol Alcohol. 2016 Nov; 51 (6):698-701 Epub 2016 June 06
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  181. Allen JI, Wang TC, Cohen WS, Shah VH. How to Succeed in Academic Gastroenterology. Gastroenterology. 2016 Oct; 151 (4):578-581.e6 Epub 2016 Aug 27
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  182. Cuervo H, Nielsen CM, Simonetto DA, Ferrell L, Shah VH, Wang RA. Endothelial notch signaling is essential to prevent hepatic vascular malformations in mice. Hepatology. 2016 Oct; 64 (4):1302-1316 Epub 2016 Aug 04
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  183. Marrone G, Shah VH, Gracia-Sancho J. Sinusoidal communication in liver fibrosis and regeneration. J Hepatol. 2016 Sep; 65 (3):608-17 Epub 2016 May 02
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  184. Kostallari E, Shah VH. Angiocrine signaling in the hepatic sinusoids in health and disease. Am J Physiol Gastrointest Liver Physiol. 2016 Aug 1; 311 (2):G246-51 Epub 2016 June 10
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  185. Dunn W, Shah VH. Pathogenesis of Alcoholic Liver Disease. Clin Liver Dis. 2016 Aug; 20 (3):445-56 Epub 2016 Mar 28
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  186. Baig MS, Yaqoob U, Cao S, Saqib U, Shah VH. Non-canonical role of matrix metalloprotease (MMP) in activation and migration of hepatic stellate cells (HSCs). Life Sci. 2016 Jun 15; 155:155-60 Epub 2016 Apr 29
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  187. Nagy LE, Ding WX, Cresci G, Saikia P, Shah VH. Linking Pathogenic Mechanisms of Alcoholic Liver Disease With Clinical Phenotypes. Gastroenterology. 2016 Jun; 150 (8):1756-68 Epub 2016 Feb 23
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  188. Greuter T, Shah VH. Hepatic sinusoids in liver injury, inflammation, and fibrosis: new pathophysiological insights. J Gastroenterol. 2016 Jun; 51 (6):511-9 Epub 2016 Mar 03
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  189. Arab JP, Shah VH. Statins and portal hypertension: A tale of two models. Hepatology. 2016 Jun; 63 (6):2044-7
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  190. Hirsova P, Ibrahim SH, Krishnan A, Verma VK, Bronk SF, Werneburg NW, Charlton MR, Shah VH, Malhi H, Gores GJ. Lipid-Induced Signaling Causes Release of Inflammatory Extracellular Vesicles From Hepatocytes. Gastroenterology. 2016 Apr; 150 (4):956-67 Epub 2016 Jan 05
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  191. Verma VK, Li H, Wang R, Hirsova P, Mushref M, Liu Y, Cao S, Contreras PC, Malhi H, Kamath PS, Gores GJ, Shah VH. Alcohol stimulates macrophage activation through caspase-dependent hepatocyte derived release of CD40L containing extracellular vesicles. J Hepatol. 2016 Mar; 64 (3):651-60 Epub 2015 Nov 26
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  192. Singal AK, Shah VH. Therapeutic Strategies for the Treatment of Alcoholic Hepatitis. Semin Liver Dis. 2016 Feb; 36: (1)56-68.
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  193. Shah VH, Gores GJ, LaRusso NF. Hail to the chief-Keith Lindor, our new AASLD president. Hepatology. 2016 Feb; 63 (2):357-9 Epub 2015 Dec 18
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  194. Wang R, Ding Q, Yaqoob U, de Assuncao TM, Verma VK, Hirsova P, Cao S, Mukhopadhyay D, Huebert RC, Shah VH. Exosome Adherence and Internalization by Hepatic Stellate Cells Triggers Sphingosine 1-Phosphate-dependent Migration. J Biol Chem. 2015 Dec 25; 290 (52):30684-96 Epub 2015 Nov 03
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  195. Mushref M, Shah VH. Getting a NOTCH-up on Macrophage Activation in Alcoholic Liver Disease. Gastroenterology 2015 Dec; 149 (7):1979-80 Epub 2015 Oct 20
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  196. Singh S, Murad MH, Chandar AK, Bongiorno CM, Singal AK, Atkinson SR, Thursz MR, Loomba R, Shah VH. Comparative Effectiveness of Pharmacological Interventions for Severe Alcoholic Hepatitis: A Systematic Review and Network Meta-analysis. Gastroenterology. 2015 Oct; 149 (4):958-70.e12 Epub 2015 June 16
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  197. Shah VH. Managing alcoholic liver disease. Clin Mol Hepatol. 2015 Sep; 21 (3):212-9 Epub 2015 Sept 30
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  198. Gao B, Shah VH. Combination therapy: New hope for alcoholic hepatitis? Clin Res Hepatol Gastroenterol. 2015 Sep; 39 Suppl 1 (Suppl 1):S7-S11 Epub 2015 July 17
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  199. Wang Y, Cao Y, Yamada S, Thirunavukkarasu M, Nin V, Joshi M, Rishi MT, Bhattacharya S, Camacho-Pereira J, Sharma AK, Shameer K, Kocher JP, Sanchez JA, Wang E, Hoeppner LH, Dutta SK, Leof EB, Shah V, Claffey KP, Chini EN, Simons M, Terzic A, Maulik N, Mukhopadhyay D. Cardiomyopathy and Worsened Ischemic Heart Failure in SM22-alpha Cre-Mediated Neuropilin-1 Null Mice: Dysregulation of PGC1alpha and Mitochondrial Homeostasis. Arterioscler Thromb Vasc Biol. 2015 Jun; 35 (6):1401-12 Epub 2015 Apr 16
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  200. Bosch J, Groszmann RJ, Shah VH. Evolution in the understanding of the pathophysiological basis of portal hypertension: How changes in paradigm are leading to successful new treatments. J Hepatol. 2015 Apr; 62 (1 Suppl):S121-30
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  201. Kang N, Shah VH, Urrutia R. Membrane-to-Nucleus Signals and Epigenetic Mechanisms for Myofibroblastic Activation and Desmoplastic Stroma: Potential Therapeutic Targets for Liver Metastasis? Mol Cancer Res. 2015 Apr; 13 (4):604-12 Epub 2014 Dec 29
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  202. Giugliano S, Kriss M, Golden-Mason L, Dobrinskikh E, Stone AE, Soto-Gutierrez A, Mitchell A, Khetani SR, Yamane D, Stoddard M, Li H, Shaw GM, Edwards MG, Lemon SM, Gale M Jr, Shah VH, Rosen HR. Hepatitis C virus infection induces autocrine interferon signaling by human liver endothelial cells and release of exosomes, which inhibits viral replication. Gastroenterology. 2015 Feb; 148 (2):392-402.e13 Epub 2014 Nov 04
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  203. Simonetto DA, Yang HY, Yin M, de Assuncao TM, Kwon JH, Hilscher M, Pan S, Yang L, Bi Y, Beyder A, Cao S, Simari RD, Ehman R, Kamath PS, Shah VH. Chronic passive venous congestion drives hepatic fibrogenesis via sinusoidal thrombosis and mechanical forces. Hepatology. 2015 Feb; 61 (2):648-59 Epub 2015 Jan 05
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  204. Urrunaga NH, Jadeja RN, Rachakonda V, Ahmad D, McLean LP, Cheng K, Shah V, Twaddell WS, Raufman JP, Khurana S. M1 muscarinic receptors modify oxidative stress response to acetaminophen-induced acute liver injury. Free Radic Biol Med. 2015 Jan; 78:66-81 Epub 2014 Oct 31
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  205. Tu K, Li J, Verma VK, Liu C, Billadeau DD, Lamprecht G, Xiang X, Guo L, Dhanasekaran R, Roberts LR, Shah VH, Kang N. Vasodilator-stimulated phosphoprotein promotes activation of hepatic stellate cells by regulating Rab11-dependent plasma membrane targeting of transforming growth factor beta receptors. Hepatology. 2015 Jan; 61 (1):361-74 Epub 2014 Sept 19
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  206. Liu C, Li J, Xiang X, Guo L, Tu K, Liu Q, Shah VH, Kang N. PDGF receptor-a promotes TGF-ß signaling in hepatic stellate cells via transcriptional and posttranscriptional regulation of TGF-ß receptors. Am J Physiol Gastrointest Liver Physiol. 2014 Oct 01; 307(7):G749-59. Epub 2014 Aug 28.
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  207. Iwakiri Y, Shah V, Rockey DC. Vascular pathobiology in chronic liver disease and cirrhosis - current status and future directions. J Hepatol. 2014 Oct; 61 (4):912-24 Epub 2014 June 06
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  208. Bi Y, Mukhopadhyay D, Drinane M, Ji B, Li X, Cao S, Shah VH. Endocytosis of collagen by hepatic stellate cells regulates extracellular matrix dynamics. Am J Physiol Cell Physiol. 2014 Oct 1; 307 (7):C622-33 Epub 2014 July 30
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  209. Bi Y, Li J, Ji B, Kang N, Yang L, Simonetto DA, Kwon JH, Kamath M, Cao S, Shah V. Sphingosine-1-phosphate mediates a reciprocal signaling pathway between stellate cells and cancer cells that promotes pancreatic cancer growth. Am J Pathol. 2014 Oct; 184 (10):2791-802 Epub 2014 Aug 08
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  210. Geng ZM, Li QH, Li WZ, Zheng JB, Shah V. Activated human hepatic stellate cells promote growth of human hepatocellular carcinoma in a subcutaneous xenograft nude mouse model. Cell Biochem Biophys. 2014 Sep; 70(1):337-47.
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  211. Mehta G, Gustot T, Mookerjee RP, Garcia-Pagan JC, Fallon MB, Shah VH, Moreau R, Jalan R. Inflammation and portal hypertension - the undiscovered country. J Hepatol. 2014 Jul; 61 (1):155-63 Epub 2014 Mar 18
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  212. de Assuncao TM, Lomberk G, Cao S, Yaqoob U, Mathison A, Simonetto DA, Huebert RC, Urrutia RA, Shah VH. New role for Kruppel-like factor 14 as a transcriptional activator involved in the generation of signaling lipids. J Biol Chem. 2014 May 30; 289 (22):15798-809 Epub 2014 Apr 23
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  213. Simonetto DA, Shah VH, Kamath PS. Primary prophylaxis of esophageal varices. Clinics in Liver Disease.2014;18:(2)335-45.
  214. Altamirano J, Miquel R, Katoonizadeh A, Abraldes JG, Duarte-Rojo A, Louvet A, Augustin S, Mookerjee RP, Michelena J, Smyrk TC, Buob D, Leteurtre E, Rincon D, Ruiz P, Garcia-Pagan JC, Guerrero-Marquez C, Jones PD, Barritt AS 4th, Arroyo V, Bruguera M, Banares R, Gines P, Caballeria J, Roskams T, Nevens F, Jalan R, Mathurin P, Shah VH, Bataller R. A histologic scoring system for prognosis of patients with alcoholic hepatitis. Gastroenterology. 2014 May; 146 (5):1231-9.e1-6 Epub 2014 Jan 15
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  215. Simonetto DA, Shah VH, Kamath PS. Primary prophylaxis of variceal bleeding. Clin Liver Dis. 2014 May; 18 (2):335-45 Epub 2014 Feb 25
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  216. Asrani SK, Talwalkar JA, Kamath PS, Shah VH, Saracino G, Jennings L, Gross JB, Venkatesh S, Ehman RL. Role of magnetic resonance elastography in compensated and decompensated liver disease. J Hepatol. 2014 May; 60 (5):934-9 Epub 2013 Dec 19
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  217. Yang L, Kwon J, Popov Y, Gajdos GB, Ordog T, Brekken RA, Mukhopadhyay D, Schuppan D, Bi Y, Simonetto D, Shah VH. Vascular endothelial growth factor promotes fibrosis resolution and repair in mice. Gastroenterology. 2014 May; 146 (5):1339-50.e1 Epub 2014 Feb 04
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  218. Singal AK, Kamath PS, Gores GJ, Shah VH. Alcoholic hepatitis: current challenges and future directions. Clin Gastroenterol Hepatol. 2014 Apr; 12 (4):555-64; quiz e31-2 Epub 2013 June 28
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  219. Granzow M, Schierwagen R, Klein S, Kowallick B, Huss S, Linhart M, Mazar IGR, Gortzen J, Vogt A, Schildberg FA, Gonzalez-Carmona MA, Wojtalla A, Kramer B, Nattermann J, Siegmund SV, Werner N, Fürst DO, Laleman W, Knolle P, Shah VH, Sauerbruch T, Trebicka J. Angiotensin-II type 1 receptor-mediated Janus kinase 2 activation induces liver fibrosis. Hepatology. 2014; 60(1):334-48.
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  220. Yaqoob U, Jagavelu K, Shergill U, de Assuncao T, Cao S, Shah VH. FGF21 promotes endothelial cell angiogenesis through a dynamin-2 and Rab5 dependent pathway. PLoS One. 2014; 9 (5):e98130 Epub 2014 May 21
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  221. Joshi HP, Subramanian IV, Schnettler EK, Ghosh G, Rupaimoole R, Evans C, Saluja M, Jing Y, Cristina I, Roy S, Zeng Y, Shah VH, Sood AK, Ramakrishnan S. Dynamin 2 along with microRNA-199a reciprocally regulate hypoxia-inducible factors and ovarian cancer metastasis. Proc Natl Acad Sci U S A. 2014; 111(14):5331-6.
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  222. Seo YS, Kwon JH, Yaqoob U, Yang L, De Assuncao TM, Simonetto DA, Verma VK, Shah VH. HMGB1 recruits hepatic stellate cells and liver endothelial cells to sites of ethanol-induced parenchymal cell injury. Am J Physiol Gastrointest Liver Physiol. 2013 Dec; 305 (11):G838-48 Epub 2013 Oct 03
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  223. Singal AK, Kamath PS, Francisco Ziller N, DiCecco S, Shoreibah M, Kremers W, Charlton MR, Heimbach JK, Watt KD, Shah VH. Nutritional status of patients with alcoholic cirrhosis undergoing liver transplantation: time trends and impact on survival. Transpl Int. 2013 Aug; 26 (8):788-94 Epub 2013 June 11
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  224. Bi Y, Venkatesh SK, Shah VH. Detecting fibrosis without a liver biopsy: getting to the fat of the issue. Hepatol Int. 2013 Jul; 7 (3):792-4 Epub 2013 July 18
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  225. Drinane MC, Shah VH. Alcoholic hepatitis: Diagnosis and prognosis. Clin Liver Dis (Hoboken). 2013 Apr; 2 (2):80-83 Epub 2013 Apr 24
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  226. Liu C, Billadeau DD, Abdelhakim H, Leof E, Kaibuchi K, Bernabeu C, Bloom GS, Yang L, Boardman L, Shah VH, Kang N. IQGAP1 suppresses TbetaRII-mediated myofibroblastic activation and metastatic growth in liver. J Clin Invest. 2013 Mar; 123 (3):1138-56 Epub 2013 Feb 01
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  227. Mathison A, Grzenda A, Lomberk G, Velez G, Buttar N, Tietz P, Hendrickson H, Liebl A, Xiong YY, Gores G, Fernandez-Zapico M, Larusso NF, Faubion W, Shah VH, Urrutia R. Role for Kruppel-like transcription factor 11 in mesenchymal cell function and fibrosis. PLoS One. 2013; 8 (9):e75311 Epub 2013 Sept 17
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  228. Seo YS, Shah VH. The role of gut-liver axis in the pathogenesis of liver cirrhosis and portal hypertension. Clin Mol Hepatol. 2012 Dec; 18 (4):337-46 Epub 2012 Dec 21
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  229. Simonetto DA, Shah VH. Primary prophylaxis of esophageal variceal bleeding. Clin Liver Dis (Hoboken). 2012 Nov; 1 (5):147-150 Epub 2012 Nov 09
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  230. Yaqoob U, Cao S, Shergill U, Jagavelu K, Geng Z, Yin M, de Assuncao TM, Cao Y, Szabolcs A, Thorgeirsson S, Schwartz M, Yang JD, Schwartz M, Ehman R, Roberts L, Mukhopadhyay D, Shah VH. Neuropilin-1 stimulates tumor growth by increasing fibronectin fibril assembly in the tumor microenvironment. Cancer Res. 2012 Aug 15; 72 (16):4047-59 Epub 2012 June 27
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  231. Zhu Q, Zou L, Jagavelu K, Simonetto DA, Huebert RC, Jiang ZD, DuPont HL, Shah VH. Intestinal decontamination inhibits TLR4 dependent fibronectin-mediated cross-talk between stellate cells and endothelial cells in liver fibrosis in mice. J Hepatol. 2012 Apr; 56 (4):893-9 Epub 2011 Dec 13
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  232. Zou L, Cao S, Kang N, Huebert RC, Shah VH. Fibronectin induces endothelial cell migration through beta1 integrin and Src-dependent phosphorylation of fibroblast growth factor receptor-1 at tyrosines 653/654 and 766. J Biol Chem. 2012 Mar 2; 287 (10):7190-202 Epub 2012 Jan 14
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  233. Sethi S, Simonetto DA, Abdelmoneim SS, Campion MB, Kaloiani I, Clayton AC, Kremers WK, Halling KC, Kamath PS, Talwalkar J, Shah VH. Comparison of circulating endothelial cell/platelet count ratio to aspartate transaminase/platelet ratio index for identifying patients with cirrhosis. J Clin Exp Hepatol. 2012 Mar; 2 (1):19-26 Epub 2012 Apr 12
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  234. Huebert RC, Jagavelu K, Hendrickson HI, Vasdev MM, Arab JP, Splinter PL, Trussoni CE, Larusso NF, Shah VH. Aquaporin-1 promotes angiogenesis, fibrosis, and portal hypertension through mechanisms dependent on osmotically sensitive microRNAs. Am J Pathol. 2011 Oct; 179 (4):1851-60 Epub 2011 Aug 18
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  235. Singal AK, Shah VH. Alcoholic hepatitis: prognostic models and treatment. Gastroenterol Clin North Am. 2011 Sep; 40(3):611-39.
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  236. Seo YS, Shah VH. Pathophysiology of portal hypertension and its clinical links. J Clin Exp Hepatol. 2011 Sep; 1 (2):87-93 Epub 2011 Nov 09
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  237. Kang N, Gores GJ, Shah VH. Hepatic stellate cells: partners in crime for liver metastases? Hepatology. 2011 Aug; 54 (2):707-13
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  238. Thabut D, Routray C, Lomberk G, Shergill U, Glaser K, Huebert R, Patel L, Masyuk T, Blechacz B, Vercnocke A, Ritman E, Ehman R, Urrutia R, Shah V. Complementary vascular and matrix regulatory pathways underlie the beneficial mechanism of action of sorafenib in liver fibrosis. Hepatology. 2011 Aug; 54 (2):573-85 Epub 2011 June 26
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  239. Routray C, Liu C, Yaqoob U, Billadeau DD, Bloch KD, Kaibuchi K, Shah VH, Kang N. Protein kinase G signaling disrupts Rac1-dependent focal adhesion assembly in liver specific pericytes. Am J Physiol Cell Physiol. 2011 Jul; 301(1):C66-74. Epub 2011 Mar 30.
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  240. Zhang C, Thabut D, Kamath PS, Shah VH. Oesophageal varices in cirrhotic patients: from variceal screening to primary prophylaxis of the first oesophageal variceal bleeding. Liver Int. 2011 Jan; 31(1):108-19. Epub 2010 Oct 14.
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  241. Vaa BE, Asrani SK, Dunn W, Kamath PS, Shah VH. Influence of serum sodium on MELD-based survival prediction in alcoholic hepatitis. Mayo Clin Proc. 2011 Jan; 86 (1):37-42
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  242. Khan JA, Kudgus RA, Szabolcs A, Dutta S, Wang E, Cao S, Curran GL, Shah V, Curley S, Mukhopadhyay D, Robertson JD, Bhattacharya R, Mukherjee P. Designing nanoconjugates to effectively target pancreatic cancer cells in vitro and in vivo. PLoS One. 2011; 6 (6):e20347 Epub 2011 June 27
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  243. Pereira A, Witek RP, Syn WK, Choi SS, Bradrick S, Karaca GF, Agboola KM, Jung Y, Omenetti A, Moylan CA, Yang L, Fernandez-Zapico ME, Jhaveri R, Shah VH, Pereira FE, Diehl AM. Viral factors induce Hedgehog pathway activation in humans with viral hepatitis, cirrhosis, and hepatocellular carcinoma. Lab Invest. 2010 Dec; 90 (12):1690-703 Epub 2010 Aug 09
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  244. Huebert RC, Jagavelu K, Liebl AF, Huang BQ, Splinter PL, LaRusso NF, Urrutia RA, Shah VH. Immortalized liver endothelial cells: a cell culture model for studies of motility and angiogenesis. Lab Invest. 2010 Dec; 90 (12):1770-81 Epub 2010 July 19
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  245. Costales P, Aledo R, Vernia S, Das A, Shah VH, Casado M, Badimon L, Llorente-Cortes V. Selective role of sterol regulatory element binding protein isoforms in aggregated LDL-induced vascular low density lipoprotein receptor-related protein-1 expression. Atherosclerosis. 2010 Dec; 213(2):458-68. Epub 2010 Oct 08.
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  246. Thabut D, Shah V. Intrahepatic angiogenesis and sinusoidal remodeling in chronic liver disease: new targets for the treatment of portal hypertension? J Hepatol. 2010 Nov; 53 (5):976-80 Epub 2010 July 24
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  247. Cao Y, Szabolcs A, Dutta SK, Yaqoob U, Jagavelu K, Wang L, Leof EB, Urrutia RA, Shah VH, Mukhopadhyay D. Neuropilin-1 mediates divergent R-Smad signaling and the myofibroblast phenotype. J Biol Chem. 2010 Oct 8; 285 (41):31840-8 Epub 2010 July 30
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  248. Kang N, Yaqoob U, Geng Z, Bloch K, Liu C, Gomez T, Billadeau D, Shah V. Focal adhesion assembly in myofibroblasts fosters a microenvironment that promotes tumor growth. Am J Pathol. 2010 Oct; 177(4):1888-900. Epub 2010 Aug 27.
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  249. Jiang JX, Venugopal S, Serizawa N, Chen X, Scott F, Li Y, Adamson R, Devaraj S, Shah V, Gershwin ME, Friedman SL, Torok NJ. Reduced nicotinamide adenine dinucleotide phosphate oxidase 2 plays a key role in stellate cell activation and liver fibrogenesis in vivo. Gastroenterology. 2010 Oct; 139(4):1375-84. Epub 2010 Jun 01.
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  250. Jagavelu K, Routray C, Shergill U, O'Hara SP, Faubion W, Shah VH. Endothelial cell toll-like receptor 4 regulates fibrosis-associated angiogenesis in the liver. Hepatology. 2010 Aug; 52 (2):590-601
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  251. Paula H, Asrani SK, Boetticher NC, Pedersen R, Shah VH, Kim WR. Alcoholic liver disease-related mortality in the United States: 1980-2003. Am J Gastroenterol. 2010 Aug; 105 (8):1782-7 Epub 2010 Feb 23
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  252. Das A, Mukherjee P, Singla SK, Guturu P, Frost MC, Mukhopadhyay D, Shah VH, Patra CR. Fabrication and characterization of an inorganic gold and silica nanoparticle mediated drug delivery system for nitric oxide. Nanotechnology. 2010 Jul 30; 21 (30):305102 Epub 2010 July 08
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  253. Huebert RC, Vasdev MM, Shergill U, Das A, Huang BQ, Charlton MR, LaRusso NF, Shah VH. Aquaporin-1 facilitates angiogenic invasion in the pathological neovasculature that accompanies cirrhosis. Hepatology. 2010 Jul; 52 (1):238-48
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  254. Cao S, Yaqoob U, Das A, Shergill U, Jagavelu K, Huebert RC, Routray C, Abdelmoneim S, Vasdev M, Leof E, Charlton M, Watts RJ, Mukhopadhyay D, Shah VH. Neuropilin-1 promotes cirrhosis of the rodent and human liver by enhancing PDGF/TGF-beta signaling in hepatic stellate cells. J Clin Invest. 2010 Jul; 120 (7):2379-94 Epub 2010 June 23
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  255. Das A, Shergill U, Thakur L, Sinha S, Urrutia R, Mukhopadhyay D, Shah VH. Ephrin B2/EphB4 pathway in hepatic stellate cells stimulates Erk-dependent VEGF production and sinusoidal endothelial cell recruitment. Am J Physiol Gastrointest Liver Physiol. 2010 Jun; 298 (6):G908-15 Epub 2010 Mar 25
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  256. Shergill U, Das A, Langer D, Adluri R, Maulik N, Shah VH. Inhibition of VEGF- and NO-dependent angiogenesis does not impair liver regeneration. Am J Physiol Regul Integr Comp Physiol. 2010 May; 298 (5):R1279-87
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  257. Shah VH. Alcoholic liver disease: the buzz may be gone, but the hangover remains. Hepatology. 2010 May; 51(5):1483-4.
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  258. Abdelmoneim SS, Talwalkar J, Sethi S, Kamath P, Fathalla MM, Kipp BR, Campion MB, Clayton AC, Halling KC, Shah VH. A prospective pilot study of circulating endothelial cells as a potential new biomarker in portal hypertension. Liver Int. 2010 Feb; 30 (2):191-7 Epub 2009 Oct 19
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  259. Roberts KE, Kawut SM, Krowka MJ, Brown RS, Trotter JF, Shah V, Peter I, Tighiouart H, Mitra N, Handorf E, Knowles JA, Zacks S, Fallon MB. Genetic risk factors for hepatopulmonary syndrome in patients with advanced liver disease. Gastroenterology. 2010; 139(1).
  260. Mathison A, Liebl A, Bharucha J, Mukhopadhyay D, Lomberk G, Shah V, Urrutia R. Pancreatic stellate cell models for transcriptional studies of desmoplasia-associated genes. Pancreatology. 2010; 10 (4):505-16 Epub 2010 Sept 16
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  261. Patra CR, Abdel Moneim SS, Wang E, Dutta S, Patra S, Eshed M, Mukherjee P, Gedanken A, Shah VH, Mukhopadhyay D. In vivo toxicity studies of europium hydroxide nanorods in mice. Toxicol Appl Pharmacol. 2009 Oct 1; 240 (1):88-98 Epub 2009 July 17
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  262. Guturu P, Shah V. New insights into the pathobiology of portal hypertension. Hepatol Res. 2009 Oct; 39(10):1016-9.
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  263. Akazawa Y, Mott JL, Bronk SF, Werneburg NW, Kahraman A, Guicciardi ME, Meng XW, Kohno S, Shah VH, Kaufmann SH, McNiven MA, Gores GJ. Death receptor 5 internalization is required for lysosomal permeabilization by TRAIL in malignant liver cell lines. Gastroenterology. 2009 Jun; 136 (7):2365-2376.e1-7 Epub 2009 Mar 09
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  264. Das A, Yaqoob U, Mehta D, Shah VH. FXR promotes endothelial cell motility through coordinated regulation of FAK and MMP-9. Arterioscler Thromb Vasc Biol. 2009 Apr; 29 (4):562-70 Epub 2009 Jan 15
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  265. Vaa Brianna E, Shah VH. Alcoholic Liver Disease—An Update. US Gastroenterology & Hepatology. 2009; 5:44-48.
  266. Guturu P, Shah V, Urrutia R. Interplay of tumor microenvironment cell types with parenchymal cells in pancreatic cancer development and therapeutic implications. J Gastrointest Cancer. 2009; 40 (1-2):1-9 Epub 2009 June 10
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  267. Boetticher NC, Peine CJ, Kwo P, Abrams GA, Patel T, Aqel B, Boardman L, Gores GJ, Harmsen WS, McClain CJ, Kamath PS, Shah VH. A randomized, double-blinded, placebo-controlled multicenter trial of etanercept in the treatment of alcoholic hepatitis. Gastroenterology. 2008 Dec; 135 (6):1953-60 Epub 2008 Sept 13
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  268. Jiang JX, Mikami K, Shah VH, Torok NJ. Leptin induces phagocytosis of apoptotic bodies by hepatic stellate cells via a Rho guanosine triphosphatase-dependent mechanism. Hepatology. 2008 Nov; 48(5):1497-505.
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  269. Decker NK, Abdelmoneim SS, Yaqoob U, Hendrickson H, Hormes J, Bentley M, Pitot H, Urrutia R, Gores GJ, Shah VH. Nitric oxide regulates tumor cell cross-talk with stromal cells in the tumor microenvironment of the liver. Am J Pathol. 2008 Oct; 173 (4):1002-12 Epub 2008 Aug 28
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  270. Fallon MB, Krowka MJ, Brown RS, Trotter JF, Zacks S, Roberts KE, Shah VH, Kaplowitz N, Forman L, Wille K, Kawut SM, Pulmonary Vascular Complications of Liver Disease Study Group. Impact of hepatopulmonary syndrome on quality of life and survival in liver transplant candidates. Gastroenterology. 2008 Oct; 135(4):1168-75. Epub 2008 Jun 20.
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  271. Semela D, Das A, Langer D, Kang N, Leof E, Shah V. Platelet-derived growth factor signaling through ephrin-b2 regulates hepatic vascular structure and function. Gastroenterology. 2008 Aug; 135 (2):671-9 Epub 2008 Apr 16
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  272. Perri RE, Shah VH. Pentoxifylline: not just for alcoholic hepatitis anymore? Hepatol Int. 2008 Jun; 2(2):137-9. Epub 2008 Apr 08.
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  273. Langer DA, Das A, Semela D, Kang-Decker N, Hendrickson H, Bronk SF, Katusic ZS, Gores GJ, Shah VH. Nitric oxide promotes caspase-independent hepatic stellate cell apoptosis through the generation of reactive oxygen species. Hepatology. 2008 Jun; 47 (6):1983-93
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  274. Iwakiri Y, Grisham M, Shah V. Vascular biology and pathobiology of the liver: Report of a single-topic symposium. Hepatology. 2008 May; 47(5):1754-63.
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  275. Distrutti E, Mencarelli A, Santucci L, Renga B, Orlandi S, Donini A, Shah V, Fiorucci S. The methionine connection: homocysteine and hydrogen sulfide exert opposite effects on hepatic microcirculation in rats. Hepatology. 2008 Feb; 47(2):659-67.
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  276. Patra CR, Cao S, Safgren S, Bhattacharya R, Ames MM, Shah V, Reid JM. Intracellular fate of a targeted delivery system. J. Biomed. Nanotechnol. 2008; 4(4):508-14.
  277. Shah V. Molecular mechanisms of increased intrahepatic resistance in portal hypertension. J Clin Gastroenterol. 2007 Nov-Dec; 41(10 Suppl 3):S259-61.
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  278. Bernatchez PN, Acevedo L, Fernandez-Hernando C, Murata T, Chalouni C, Kim J, Erdjument-Bromage H, Shah V, Gratton JP, McNally EM, Tempst P, Sessa WC. Myoferlin regulates vascular endothelial growth factor receptor-2 stability and function. J Biol Chem. 2007 Oct 19; 282(42):30745-53. Epub 2007 Aug 16.
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  279. Lee JS, Semela D, Iredale J, Shah VH. Sinusoidal remodeling and angiogenesis: a new function for the liver-specific pericyte? Hepatology. 2007 Mar; 45(3):817-25.
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  280. Kang-Decker N, Cao S, Chatterjee S, Yao J, Egan LJ, Semela D, Mukhopadhyay D, Shah V. Nitric oxide promotes endothelial cell survival signaling through S-nitrosylation and activation of dynamin-2. J Cell Sci. 2007 Feb 1; 120 (Pt 3):492-501
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  281. Iwakiri Y, Satoh A, Chatterjee S, Toomre DK, Chalouni CM, Fulton D, Groszmann RJ, Shah VH, Sessa WC. Nitric oxide synthase generates nitric oxide locally to regulate compartmentalized protein S-nitrosylation and protein trafficking. Proc Natl Acad Sci U S A. 2006 Dec 26; 103(52):19777-82. Epub 2006 Dec 14.
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  282. Das A, Fernandez-Zapico ME, Cao S, Yao J, Fiorucci S, Hebbel RP, Urrutia R, Shah VH. Disruption of an SP2/KLF6 repression complex by SHP is required for farnesoid X receptor-induced endothelial cell migration. J Biol Chem. 2006 Dec 22; 281 (51):39105-13 Epub 2006 Oct 27
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  283. Trushina E, Singh RD, Dyer RB, Cao S, Shah VH, Parton RG, Pagano RE, McMurray CT. Mutant huntingtin inhibits clathrin-independent endocytosis and causes accumulation of cholesterol in vitro and in vivo. Hum Mol Genet. 2006 Dec 15; 15 (24):3578-91
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  284. Dunn W, Angulo P, Sanderson S, Jamil LH, Stadheim L, Rosen C, Malinchoc M, Kamath PS, Shah VH. Utility of a new model to diagnose an alcohol basis for steatohepatitis. Gastroenterology. 2006 Oct; 131 (4):1057-63 Epub 2006 Aug 10
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  285. Wang XL, Lu T, Cao S, Shah VH, Lee HC. Inhibition of ATP binding to the carboxyl terminus of Kir6.2 by epoxyeicosatrienoic acids. Biochim Biophys Acta. 2006 Sep; 1761 (9):1041-9 Epub 2006 July 08
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  286. Shah VH, Kamath P. Management of portal hypertension. Postgrad Med. 2006 Sep-Oct; 119 (3):14-8
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  287. Wendt MK, Johanesen PA, Kang-Decker N, Binion DG, Shah V, Dwinell MB. Silencing of epithelial CXCL12 expression by DNA hypermethylation promotes colonic carcinoma metastasis. Oncogene. 2006 Aug 17; 25(36):4986-97. Epub 2006 Mar 27.
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  288. Semela D, Langer DA, Shah V. GRK2 makes trouble: a no-NO in portal hypertension. Gastroenterology. 2006 Mar; 130(3):1001-3; discussion 1003.
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  289. Perri RE, Langer DA, Chatterjee S, Gibbons SJ, Gadgil J, Cao S, Farrugia G, Shah VH. Defects in cGMP-PKG pathway contribute to impaired NO-dependent responses in hepatic stellate cells upon activation. Am J Physiol Gastrointest Liver Physiol. 2006 Mar; 290: (3)G535-42.
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  290. Anan A, Baskin-Bey ES, Bronk SF, Werneburg NW, Shah VH, Gores GJ. Proteasome inhibition induces hepatic stellate cell apoptosis. Hepatology. 2006 Feb; 43 (2):335-44
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  291. Langer DA, Shah VH. Nitric oxide and portal hypertension: interface of vasoreactivity and angiogenesis. J Hepatol. 2006 Jan; 44(1):209-16. Epub 2005 Nov 04.
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  292. Billadeau DD, Chatterjee S, Bramati P, Sreekumar R, Shah V, Hedin K, Urrutia R. Characterization of the CXCR4 signaling in pancreatic cancer cells. Int J Gastrointest Cancer. 2006; 37 (4):110-9
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  293. Bhattacharya R, Kang-Decker N, Hughes DA, Mukherjee P, Shah V, McNiven MA, Mukhopadhyay D. Regulatory role of dynamin-2 in VEGFR-2/KDR-mediated endothelial signaling. FASEB J. 2005 Oct; 19(12):1692-4. Epub 2005 Jul 27.
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  294. Fiorucci S, Antonelli E, Mencarelli A, Orlandi S, Renga B, Rizzo G, Distrutti E, Shah V, Morelli A. The third gas: H2S regulates perfusion pressure in both the isolated and perfused normal rat liver and in cirrhosis. Hepatology. 2005 Sep; 42(3):539-48.
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  295. Lee JS, Kang Decker N, Chatterjee S, Yao J, Friedman S, Shah V. Mechanisms of nitric oxide interplay with Rho GTPase family members in modulation of actin membrane dynamics in pericytes and fibroblasts. Am J Pathol. 2005 Jun; 166 (6):1861-70
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  296. Kamath PS, Shah V. Does nadolol improve the efficacy of endoscopic variceal ligation in the treatment of variceal bleeding? Nat Clin Pract Gastroenterol Hepatol. 2005 Jun; 2(6):254-5.
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  297. Wang XL, Ye D, Peterson TE, Cao S, Shah VH, Katusic ZS, Sieck GC, Lee HC. Caveolae targeting and regulation of large conductance Ca(2+)-activated K+ channels in vascular endothelial cells. J Biol Chem. 2005 Mar 25; 280 (12):11656-64 Epub 2005 Jan 23
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  298. Dunn W, Jamil LH, Brown LS, Wiesner RH, Kim WR, Menon KV, Malinchoc M, Kamath PS, Shah V. MELD accurately predicts mortality in patients with alcoholic hepatitis. Hepatology. 2005 Feb; 41 (2):353-8
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  299. Cao S, Fernandez-Zapico ME, Jin D, Puri V, Cook TA, Lerman LO, Zhu XY, Urrutia R, Shah V. KLF11-mediated repression antagonizes Sp1/sterol-responsive element-binding protein-induced transcriptional activation of caveolin-1 in response to cholesterol signaling. J Biol Chem. 2005 Jan 21; 280 (3):1901-10 Epub 2004 Nov 05
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  300. Lim I, Gibbons SJ, Lyford GL, Miller SM, Strege PR, Sarr MG, Chatterjee S, Szurszewski JH, Shah VH, Farrugia G. Carbon monoxide activates human intestinal smooth muscle L-type Ca2+ channels through a nitric oxide-dependent mechanism. Am J Physiol Gastrointest Liver Physiol. 2005 Jan; 288(1):G7-14. Epub 2004 Aug 19.
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  301. Shah V. Molecular mechanisms in the pathogenesis of cirrhotic portal hypertension: focus on nitric oxide. J Gastroenterol Hepatol. 2004 Dec; 19(s7):S145-S149.
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  302. Hassoun Z, Shah V, Lohse CM, Pankratz VS, Petrovic LM. Centrilobular necrosis after orthotopic liver transplantation: association with acute cellular rejection and impact on outcome. Liver Transpl. 2004 Apr; 10 (4):480-7
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  303. Shah V, Lyford G, Gores G, Gores G, Farrugia G. Nitric oxide in gastrointestinal health and disease. Gastroenterology. 2004 Mar; 126 (3):903-13
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  304. Menon KV, Shah V, Kamath PS. The Budd-Chiari syndrome. N Engl J Med. 2004 Feb 05; 350: (6)578-85.
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  305. Menon KV, Menon KV, Stadheim L, Kamath PS, Wiesner RH, Gores GJ, Peine CJ, Shah V. A pilot study of the safety and tolerability of etanercept in patients with alcoholic hepatitis. Am J Gastroenterol. 2004 Feb; 99 (2):255-60
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  306. Dunn W, Lerman A, Shah V. Clinical expression of endothelial dysfunction. Heart Metabolism. 2004; 22:11-16.
  307. Rockey DC, Shah V. Nitric oxide biology and the liver: Report of an AASLD Research Workshop. Hepatology. 2004 Jan; 39(1):250-7.
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  308. Gulati R, Jevremovic D, Peterson TE, Chatterjee S, Shah V, Vile RG, Simari RD. Diverse origin and function of cells with endothelial phenotype obtained from adult human blood. Circ Res. 2003 Nov 28; 93 (11):1023-5 Epub 2003 Nov 06
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  309. Chatterjee S, Cao S, Peterson TE, Simari RD, Shah V. Inhibition of GTP-dependent vesicle trafficking impairs internalization of plasmalemmal eNOS and cellular nitric oxide production. J Cell Sci. 2003 Sep 1; 116(Pt 17):3645-55. Epub 2003 Jul 22.
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  310. Hendrickson H, Chatterjee S, Cao S, Morales Ruiz M, Sessa WC, Shah V. Influence of caveolin on constitutively activated recombinant eNOS: insights into eNOS dysfunction in BDL rat liver. Am J Physiol Gastrointest Liver Physiol. 2003 Sep; 285(3):G652-60. Epub 2003 Jun 26.
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  311. Cao S, Yao J, Shah V. The proline-rich domain of dynamin-2 is responsible for dynamin-dependent in vitro potentiation of endothelial nitric-oxide synthase activity via selective effects on reductase domain function. J Biol Chem. 2003 Feb 21; 278 (8):5894-901 Epub 2002 Dec 16
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  312. Shah V, Kamath PS. Nitric oxide in liver transplantation: pathobiology and clinical implications. Liver Transpl. 2003 Jan; 9(1):1-11.
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  313. Shah V, Kamath PS. Portal hypertension: a clinical update in the pathogenesis and treatment of variceal hemorrhage and hepatic encephalopathy. Medscape Gastroenterology. 2003.
  314. Hassoun Z, Shah V, Shah V, Petrovic LM. The choice of calcineurin inhibitor does not influence centrilobular necrosis after orthotopic liver transplantation. Transplant Proc. 2002 Aug; 34 (5):1519-20
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  315. Shah VH, Kamath PS. New developments in portal hypertensive bleeding. Clinical Perspectives in Gastroenterology. 2002; 5:17-22.
  316. Shah V. Portal hypertension and the hyperdynamic circulation: nitric oxide in a haze of cannabinoid smoke. Hepatology. 2001 Nov; 34(5):1060-1.
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  317. Menon KV, Gores GJ, Shah VH. Pathogenesis, diagnosis, and treatment of alcoholic liver disease. Mayo Clin Proc. 2001 Oct; 76 (10):1021-9
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  318. Shah V, Shah V. Cellular and molecular basis of portal hypertension. Clin Liver Dis. 2001 Aug; 5 (3):629-44
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  319. Shah V, Cao S, Hendrickson H, Yao J, Katusic ZS. Regulation of hepatic eNOS by caveolin and calmodulin after bile duct ligation in rats. Am J Physiol Gastrointest Liver Physiol. 2001 Jun; 280 (6):G1209-16
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  320. Cao S, Yao J, McCabe TJ, Yao Q, Katusic ZS, Sessa WC, Shah V. Direct interaction between endothelial nitric-oxide synthase and dynamin-2. Implications for nitric-oxide synthase function. J Biol Chem. 2001 Apr 27; 276 (17):14249-56 Epub 2000 Dec 18
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  321. Nath KA, Shah V, Haggard JJ, Croatt AJ, Smith LA, Hebbel RP, Katusic ZS. Mechanisms of vascular instability in a transgenic mouse model of sickle cell disease. Am J Physiol Regul Integr Comp Physiol. 2000 Dec; 279 (6):R1949-55
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  322. Shah V, Chen AF, Cao S, Hendrickson H, Weiler D, Smith L, Yao J, Katusic ZS. Gene transfer of recombinant endothelial nitric oxide synthase to liver in vivo and in vitro. Am J Physiol Gastrointest Liver Physiol. 2000 Nov; 279 (5):G1023-30
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  323. Khurana VG, Feterik K, Springett MJ, Eguchi D, Shah V, Katusic ZS. Functional interdependence and colocalization of endothelial nitric oxide synthase and heat shock protein 90 in cerebral arteries. J Cereb Blood Flow Metab. 2000 Nov; 20(11):1563-70.
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  324. Shah V, Wiest R, Garcia-Cardena G, Cadelina G, Groszmann RJ, Sessa WC. Hsp90 regulation of endothelial nitric oxide synthase contributes to vascular control in portal hypertension. Am J Physiol. 1999 Aug; 277(2 Pt 1):G463-8.
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  325. Shah V, Wiest R, Garcia-Cardena G, Cadelina G, Groszmann RJ, Sessa WC. Hsp90 regulation of endothelial nitric oxide synthase contributes to vascular control in portal hypertension. Am J Physiol Gastrointest Liver Physiol. 1999 Aug 1; 277 (2):G463-G468
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  326. Wiest R, Shah V, Sessa WC, Groszmann RJ. NO overproduction by eNOS precedes hyperdynamic splanchnic circulation in portal hypertensive rats. Am J Physiol. 1999; 276:G1043-51.
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  327. Shah V, Toruner M, Haddad F, Cadelina G, Papapetropoulos A, Sessa WC, Groszmann RJ. Impaired endothelial nitric oxide synthase activity associated with enhanced caveolin binding in experimental liver cirrhosis. Gastroenterology. 1999; 117:1222-8.
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  328. Garcia-Cardena G, Fan R, Shah V, Sorrentino R, Cirino G, Papapetropoulos A, Sessa WC. Dynamic activation of eNOS synthase by Hsp90. Nature. 1998; 392:821-4.
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  329. Shah V, Garcia-Cardena G, Sessa WC, Groszmann RJ. The hepatic circulation in health and disease: report of a single-topic symposium. Hepatology. 1998 Jan; 27(1):279-88.
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  330. Shah V, Haddad FG, Garcia-Cardena G, Frangos JA, Mennone A, Groszmann RJ, Sessa WC. Liver sinusoidal endothelial cells are responsible for nitric oxide modulation of resistance in the hepatic sinusoids. J Clin Invest. 1997 Dec 1; 100(11):2923-30.
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  331. Shah V, Friedman AL, Navarro VJ. Immunology of liver transplantation: clinical management aspects. Gastroenterologist. 1997 Jun; 5(2):137-47.
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  332. Shah V, Waltenbaugh C, Yeldandi A. Peroxisome proliferators increase ethanol metabolism through utilization of the catalase pathway. Int J Oncol. 1997; 11:255-259.
  333. Atucha NM, Shah V, Garcia-Cardena G, Sessa WE, Groszmann RJ. Role of endothelium in the abnormal response of mesenteric vessels in rats with portal hypertension and liver cirrhosis. Gastroenterology. 1996 Dec; 111(6):1627-32.
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  334. Shah V, Marino C, Altice FL. Albendazole-induced pseudomembranous colitis. Am J Gastroenterol. 1996 Jul; 91(7):1453-4.
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  335. Shah V, Webster S, Gottstein J, Blei AT. Reduction of cerebral perfusion precedes rise of intracranial pressure in rats with ischemic fulminant liver failure. Hepatology. 1993 Jun; 17(6):1117-22.
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  336. Jacob P, Kahrilas PJ, Logemann JA, Shah V, Ha T. Upper esophageal sphincter opening and modulation during swallowing. Gastroenterology. 1989 Dec; 97(6):1469-78.
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