Proper Use

Drug information provided by: Merative, Micromedex®

A nurse or other trained health professional will give you this medicine. It is given as a shot under your skin, usually in the thigh, stomach area, or upper arm. This medicine may also be given at home to patients who do not need to be in a hospital or clinic. You or your caregiver may be trained to prepare and inject the medicine at home. Be sure that you understand how to use the medicine.

This medicine should come with a patient information leaflet and patient instructions. Read and follow these instructions carefully. Ask your doctor if you have any questions.

If you use Ebglyss™ at home, you will be shown the body areas where this shot can be given. Use a different body area each time you give yourself a shot. Keep track of where you give each shot to make sure you rotate body areas. This will help prevent skin problems. Do not inject into skin areas that are tender, red, bruised, hard, or areas that is affected by eczema or other skin problems.

This medicine comes in 2 forms: a prefilled pen and prefilled syringe.

Allow the medicine to warm to room temperature for 45 minutes. Do not warm using heat sources (eg, microwave, hot water, sunlight).

To use the prefilled pen:

  • Wash your hands with soap and water before and after using this medicine.
  • Do not shake the pen.
  • Check the liquid in the pen. It should be clear, colorless to slightly yellow to slightly brown. Do not use it if it is cloudy, discolored, or has particles in it. Do not use the pen if it looks damaged.
  • Twist off the gray base cap. Do not put the cap back on. Do not touch the needle.
  • Place and hold the clear base flat and firmly against the skin. Keep the clear base on the skin, then turn the lock ring to the unlock position.
  • Press and hold the purple injection button and listen for two loud clicks. You will hear one "click" to let you know that the injection has started. It will take up to 15 seconds to inject the full dose. You will hear a second "click" when the gray plunger is visible. This means the injection is complete.

To use the prefilled syringe:

  • Wash your hands with soap and water before and after using this medicine.
  • Do not shake the syringe.
  • Check the liquid in the syringe. It should be clear, colorless to slightly yellow to slightly brown. Do not use it if it is cloudy, discolored, or has particles in it. Do not use the syringe if it looks damaged or the needle cap is missing or not attached properly.
  • Pull the needle cap straight off. Do not put the cap back on. Do not touch the needle.
  • Gently pinch the skin with one hand. With your other hand, Insert the needle into the skin at about a 45 degree angle.
  • Push the plunger rod all the way down. Lift your thumb to release the plunger rod until the needle is covered by the needle shield.

Dosing

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

  • For moderate to severe atopic dermatitis:
    • For injection dosage form (prefilled pen or prefilled syringe):
      • Adults and children 12 years of age and older weighing 40 kilograms (kg) or more—At first, 500 milligrams (mg) (two 250 mg injections) injected under the skin at Week 0 and Week 2; followed by, 250 mg every two weeks until Week 16; then, a maintenance dose of 250 mg every four weeks.
      • Children younger than 12 years of age and children 12 years of age and older weighing less than 40 kg—Use and dose must be determined by your doctor.

Missed Dose

If you miss a dose of this medicine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.

Storage

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Store in the refrigerator. Do not freeze.

Protect the medicine from direct light. Keep the medicine in the original package until you are ready to use it. Do not use it if it has been frozen. You may store the prefilled pen or prefilled syringe at room temperature for up to 7 days. Throw the medicine away if it has been left out of the refrigerator for more than 7 days.

Throw away used needles in a hard, closed container that the needles cannot poke through. Keep this container away from children and pets.

Portions of this document last updated: Oct. 01, 2024

Copyright: © Merative US L.P. 1973, 2024. All rights reserved. Information is for End User's use only and may not be sold, redistributed or otherwise used for commercial purposes.