Polycystic kidney disease

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Doctors who treat this condition

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Displaying 11-20 out of 22 doctors available

  1. Sayeed Khalillullah, M.D.

    Sayeed Khalillullah, M.D.

    1. Nephrologist
    1. Phoenix, AZ
    Areas of focus:

    Chronic kidney disease, End-stage renal disease, Polycystic kidney disease, Acute kidney injury , Glomerular disease

  2. Napat Leeaphorn, M.D.

    Napat Leeaphorn, M.D.

    1. Transplant Nephrologist
    1. Jacksonville, FL
    Areas of focus:

    Pancreas transplant, Kidney transplant, Continuous renal replacement therapy, Post-transplant long-term care, Pre-trans...plant evaluation, Immunosuppressive drug therapy, Hemodialysis, Dialysis, Chronic kidney disease, End-stage renal disease, Diabetic nephropathy, Polycystic kidney disease, Acute kidney failure, Transplant rejection, Kidney failure

  3. Martin L. Mai, M.D.

    Martin L. Mai, M.D.

    1. Transplant Nephrologist
    1. Jacksonville, FL
    Areas of focus:

    Pancreas transplant, Kidney transplant, Post-transplant long-term care, Pre-transplant evaluation, Immunosuppressive dr...ug therapy, Chronic kidney disease, End-stage renal disease, Diabetic nephropathy, Polycystic kidney disease, Acute kidney failure, Kidney failure

  4. Katherine Oshel, M.D.

    Katherine Oshel, M.D.

    1. Transplant Nephrologist
    1. Jacksonville, FL
    Areas of focus:

    Pancreas transplant, Kidney transplant, Post-transplant long-term care, Pre-transplant evaluation, Immunosuppressive dr...ug therapy, Chronic kidney disease, End-stage renal disease, Diabetic nephropathy, Polycystic kidney disease, Acute kidney failure, Kidney injury

  5. Mary B. Prendergast, M.B., B.Ch., M.D.

    Mary B. Prendergast, M.B., B.Ch., M.D.

    1. Transplant Nephrologist
    1. Jacksonville, FL
    Areas of focus:

    Pancreas transplant, Kidney transplant, Post-transplant long-term care, Pre-transplant evaluation, Immunosuppressive dr...ug therapy, Chronic kidney disease, End-stage renal disease, Diabetic nephropathy, Polycystic kidney disease, Acute kidney failure, HIV/AIDS, General infectious diseases

  6. Mikel Prieto, M.D.

    Mikel Prieto, M.D.

    1. Transplant Surgeon
    1. Rochester, MN
    Areas of focus:

    Pancreas transplant, Donor nephrectomy, Nephrectomy, Living donor kidney transplant, Kidney donation, Preemptive kidney... transplant, Laparoscopic kidney surgery, Diabetes, Chronic kidney disease, Polycystic kidney disease, ADPKD

  7. David J. Sas, D.O.

    David J. Sas, D.O.

    1. Pediatrician
    2. Pediatric Nephrologist
    1. Rochester, MN
    Areas of focus:

    Kidney transplant, Continuous renal replacement therapy, Hemodialysis, Dialysis, Peritoneal dialysis, Chronic kidney di...sease, End-stage renal disease, Hypercalciuria, Urinary tract infection, Kidney stone, Hydronephrosis, Hyperoxaluria, Polycystic kidney disease, Kidney infection, Focal segmental glomerulosclerosis, Renal artery stenosis, Acute kidney injury , High blood pressure in children, Glomerular disease, Blood in urine, Kidney cyst, Kidney injury, Renal tubular acidosis, Renovascular disease, Primary hyperoxaluria, Minimal change disease, Membranoproliferative glomerulonephritis, Medullary sponge kidney, Nephrotic syndrome, Protein in urine, Congenital kidney disorder, Childhood nephrotic syndrome, Single kidney, Horseshoe kidney, Shrinking kidney, Multicystic kidney dysplasia, Postural proteinuria

  8. Timucin Taner, M.D., Ph.D.

    Timucin Taner, M.D., Ph.D.

    1. Transplant Surgeon
    1. Rochester, MN
    Areas of focus:

    Pancreas transplant, Donor nephrectomy, Liver transplant, Living donor liver transplant, Kidney transplant, Living dono...r kidney transplant, Living-donor transplant, Liver resection, Kidney donor evaluation, Liver donation, Living kidney donation, Nonalcoholic steatohepatitis, End-stage renal disease, Nonalcoholic fatty liver disease, Cirrhosis, Alcoholic liver disease, Primary sclerosing cholangitis, Cholangiocarcinoma, Portal hypertension, Liver cancer, Alcoholic hepatitis, Autoimmune hepatitis, Amyloidosis, Hepatocellular carcinoma, Hepatopulmonary syndrome, Primary biliary cholangitis, Budd-Chiari syndrome, Alagille syndrome, Polycystic kidney disease, Acute liver failure, Metabolic liver disease, Portopulmonary hypertension, Liver mass, Chronic liver disease, Liver tumor, Kidney failure, Polycystic liver disease, Fatty liver disease, Hepatorenal syndrome, Primary hyperoxaluria

  9. Vicente Torres, M.D., Ph.D.

    Vicente Torres, M.D., Ph.D.

    1. Internist
    2. Nephrologist
    1. Rochester, MN
    Areas of focus:

    Transplant, Pancreas transplant, Kidney transplant, Kidney stone, Polycystic kidney disease, Glomerular disease, Kidney... failure, ADPKD

  10. Cheryl L. Tran, M.D.

    Cheryl L. Tran, M.D.

    1. Pediatrician
    2. Pediatric Nephrologist
    1. Rochester, MN
    Areas of focus:

    Kidney transplant, Hemodialysis, Dialysis, Peritoneal dialysis, Chronic kidney disease, End-stage renal disease, Urinar...y tract infection, Hydronephrosis, Polycystic kidney disease, Hemolytic uremic syndrome, Kidney infection, IgA nephropathy, Focal segmental glomerulosclerosis, Renal artery stenosis, Acute kidney injury , High blood pressure in children, Glomerular disease, Blood in urine, Kidney cyst, Renal tubular acidosis, Renovascular disease, Membranous nephropathy, Minimal change disease, Membranoproliferative glomerulonephritis, Medullary sponge kidney, Nephrotic syndrome, Protein in urine, Congenital kidney disorder, Childhood nephrotic syndrome, Single kidney, Horseshoe kidney, Shrinking kidney, Multicystic kidney dysplasia, Postural proteinuria

Research

Mayo Clinic is a leader in polycystic kidney disease research. Mayo Clinic researchers discovered:

  • The main gene that causes autosomal dominant polycystic kidney disease (ADPKD).
  • The gene that causes autosomal recessive polycystic kidney disease (ARPKD).
  • A gene that causes a rare form of polycystic kidney disease associated with multiple malformations (Meckel-Gruber syndrome).
  • The polycystic kidney disease proteins polycystin 1, polycystin 2 and fibrocystin.
  • The polycystic kidney and liver disease gene GANAB.
  • Other genes that cause kidney cyst disease, such as DNAJB11.
  • A way to use CT and MRI scans to classify polycystic kidney disease and select people for clinical trials of new therapies.
  • A pioneering approach to surgery to remove diseased kidneys and transplant healthy kidneys during the same surgery.

Lab-based research at Mayo Clinic has focused on:

  • Explaining how mutations in the polycystic kidney disease genes lead to cyst development.
  • Preclinical studies in drug therapies for polycystic kidney disease, such as octreotide and vasopressin antagonists.
  • Finding effective therapies for polycystic kidney disease and liver disease.
  • Improving imaging assessments of polycystic kidney disease and liver disease.
  • Studies of polycystic kidney disease proteins in urine particles known as exosomes.
  • Testing new compounds in animal models of polycystic kidney disease.
  • Studies of the hairlike structures (primary cilia) implicated in polycystic kidney disease.

Mayo Clinic research has shown that a medicine called tolvaptan can slow the development and progression of polycystic kidney disease in animal models.

Mayo Clinic researchers also have shown that another medicine called octreotide delays the development of both polycystic kidney disease and polycystic liver disease and is a potential treatment option for people who have PKD with liver involvement.

These medicines are now in clinical trials, and tolvaptan is approved for use in some countries for polycystic kidney disease. In addition, nephrologists at Mayo Clinic are working to understand how to prevent the progression of kidney (renal) disease in patients with polycystic kidney disease.

Read more about the extensive research being done at Mayo Clinic's Robert M. and Billie Kelley Pirnie Translational Polycystic Kidney Disease (PKD) Center.

The Mayo Nephrology Collaborative Group ― a consortium of nephrologists across the United States ― develops and conducts studies aimed at improving treatment of patients with renal diseases, including polycystic kidney disease.

Publications

See a list of publications about polycystic kidney disease by Mayo Clinic doctors on PubMed, a service of the National Library of Medicine.

Research Profiles

By Mayo Clinic Staff

Polycystic kidney disease care at Mayo Clinic

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Diagnosis & treatmentCare at Mayo Clinic
Aug. 27, 2024
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Polycystic kidney disease

Research: It's all about patients

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Joseph Sirven, M.D., Professor of Neurology, Mayo Clinic: Mayo's mission is about the patient. The patient comes first. So the mission and research here is to advance how we can best help the patient, how to make sure the patient comes first in care. So in many ways, it's a cycle. It can start with as simple as an idea worked on in a laboratory, brought to the patient bedside, and if everything goes right — and let's say it's helpful or beneficial — then brought on as a standard approach. And I think that is one of the unique characteristics of Mayo's approach to research — that patient-centeredness — that really helps to put it in its own spotlight.