Osteosarcoma care at Mayo Clinic

Mayo Clinic experts are known for the highest quality expertise and resources to meet the needs of children and adults with osteosarcoma. Our experienced sarcoma teams care for hundreds of people each year who have various types of sarcoma.

Your Mayo Clinic care team

Mayo Clinic's pediatric cancer specialists come together as a team to create a customized treatment plan for your child. Pediatric oncologists work with multiple medical and surgical specialists, including but not limited to orthopedic surgeons, pediatric surgeons and pediatric rehabilitation specialists. The care team also includes pediatric nurses, child life specialists, social workers and others as needed.

If you're an adult with osteosarcoma, Mayo Clinic's experienced team of experts who treat adults will customize care to your specific needs.

Advanced diagnosis and treatment

Mayo Clinic experts will work with you to review treatment options and choose the treatment that best suits your needs and goals.

When you seek care at Mayo Clinic, you can expect:

  • A full range of treatment options to consider. Your care team carefully considers all the available treatment options to make a recommendation. The range of treatments offered includes the latest advancements in chemotherapy, surgery and radiation therapy.
  • Fertility preservation program. Certain chemotherapy and radiation treatments increase the risk of impaired fertility. As part of the Mayo Clinic Children's Center, the Fertility Preservation Program evaluates children with cancer whose disease and treatment could affect future fertility. Fertility preservation services also are available for adults.
  • Access to the latest through clinical trials. Mayo Clinic is active in sarcoma research, which gives you a chance to enroll in clinical trials to try the latest treatment innovations.

Ankle replaces knee in rotationplasty

[MUSIC PLAYING]

Shanna Decker, Cancer survivor: My knee really just started to hurt a whole lot. And it went from no pain, to debilitating pain in three weeks. So much so, that as a seven-year-old, I asked my mom to take me to the doctor.

Vivien Williams: Experts at Mayo Clinic diagnosed a rare bone cancer called osteosarcoma.

Ms. Decker: But all I knew of cancer was that people died of cancer, basically. And so when they said cancer, immediately, even though I was seven, I knew this is a bad deal. Will I survive? Things like that.

Ms. Williams: That is a question no seven-year-old should have to ponder.

Carola Arndt, M.D., Pediatric Oncology, Mayo Clinic: So treatment for osteosarcoma involves surgery and chemotherapy.

Ms. Williams: Pediatric oncologist, Dr. Carola Arndt, and orthopedic surgeon, Dr. Franklin Sim, led the multi-disciplinary team that cared for Shanna.

Franklin Sim, M.D., Orthopedic Surgery, Mayo Clinic: The tumor was in the lower end of the thigh bone.

Ms. Williams: Shanna started chemotherapy and then had surgery, which in the past, would have meant amputating her left leg above the knee. Instead, she had what was then a new and groundbreaking procedure called rotationplasty. During the operation, Dr. Sim removed the section of the thigh, or femur bone, that involves the tumor as well as the knee and part of the shinbone, or tibia. Then, he rotates the lower leg and fuses it to the femur. The ankle now becomes the knee.

Ms. Decker: So on this leg, I take it off and then this is my foot, on backwards.

Ms. Williams: It may look a bit strange but the procedure and prosthesis have allowed Shanna to do just about anything. She says it was surprisingly easy to adjust to her new normal.

Ms. Decker: And as soon as my leg healed, I was walking with a prosthetic and it took me about 30 seconds to learn how to re-walk.

Ms. Williams: Shanna, who is now 24, has accomplished a lot in the years since her diagnosis and surgery.

Ms. Decker: So I'm 16 years out of cancer now, which seems so crazy, 16 years.

Dr. Sim: And we've seen her grow through her childhood and function as she's been able to do and remain active. And now at this stage, she's finished college and she's passing it on. She's giving back.

Ms. Decker: Right after my treatment, when I was eight years old, 1999, my family started mentoring kids with cancer.

Ms. Williams: Then, in 2007, with three other families, they started an organization called Brighter Tomorrows.

Ms. Decker: It supports families emotionally, spiritually, educationally, and a little bit financially, when they're diagnosed with cancer. And we have hundreds of people in our database now.

Dr. Arndt: It makes my day. If at the end of the day or during the course of the day, I see a long-term survivor like Shanna, it puts things in perspective and it reminds me this is why we do what we do.

Ms. Decker: Helping families with cancer. Being an advocate for childhood cancer. Helping every single family who walks through the journey, so they're not by themselves.

Ms. Williams: Giving back hope, love and healing.

[MUSIC PLAYING]

Expertise and rankings

Mayo Clinic is consistently recognized by external organizations for providing outstanding patient care. These endorsements reinforce our commitment to providing expert care, tailored to the needs of each patient with osteosarcoma.

Other reasons to choose Mayo Clinic for cancer care include:

  • Experience you can trust. Mayo Clinic doctors are widely respected for their expertise in diagnosing and treating all types of cancer, including very rare types. Each year, Mayo Clinic doctors care for hundreds of people with sarcoma.
  • Comprehensive cancer center. Mayo Clinic Comprehensive Cancer Center meets the strict standards for a National Cancer Institute comprehensive cancer center. These standards recognize scientific excellence and a multispecialty approach focused on cancer prevention, diagnosis and treatment.
  • Collaborations to increase knowledge. Mayo Clinic is a member of collaborations to expand the understanding of cancer, such as the Children's Oncology Group and National Comprehensive Cancer Network. These collaborations mean that you or your child will receive coordinated diagnosis and treatment based on the latest research.

Mayo Clinic in Rochester, Minnesota, Mayo Clinic in Jacksonville, Florida, and Mayo Clinic in Phoenix/Scottsdale, Arizona, are ranked among the Best Hospitals for cancer care by U.S. News & World Report. Mayo Clinic Children's Center in Rochester is ranked the No. 1 hospital in Minnesota, and the five-state region of Iowa, Minnesota, North Dakota, South Dakota and Wisconsin, according to U.S. News & World Report's 2024–2025 "Best Children's Hospitals" rankings.

Mayo Clinic Children's Center

Highly skilled pediatric experts diagnose and treat all types of conditions in children. As a team, we work together to find answers, set goals and develop a treatment plan tailored to your child's needs.

Learn more about the Children's Center.

Locations, travel and lodging

Mayo Clinic has major campuses in Phoenix and Scottsdale, Arizona; Jacksonville, Florida; and Rochester, Minnesota. The Mayo Clinic Health System has dozens of locations in several states.

For more information on visiting Mayo Clinic, choose your location below:

Costs and insurance

Mayo Clinic works with hundreds of insurance companies and is an in-network provider for millions of people.

In most cases, Mayo Clinic doesn't require a physician referral. Some insurers require referrals or may have additional requirements for certain medical care. All appointments are prioritized on the basis of medical need.

Learn more about appointments at Mayo Clinic.

Please contact your insurance company to verify medical coverage and to obtain any needed authorization prior to your visit. Often, your insurer's customer service number is printed on the back of your insurance card.

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Dec. 22, 2023

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