Print Departments and specialties Mayo Clinic has one of the largest and most experienced practices in the United States, with campuses in Arizona, Florida and Minnesota. Staff skilled in dozens of specialties work together to ensure quality care and successful recovery. Departments that treat this condition Multiple Sclerosis and Autoimmune Neurology Neurology Neuro-ophthalmology Ophthalmology Physical Medicine and Rehabilitation Areas that research this condition Neurology Research ResearchMayo Clinic researchers in neuroregeneration and neurorehabilitation and other areas study causes, genetics, new diagnostic tests and treatments for neuromyelitis optica and related conditions. Ravulizumab (Ultomiris) is currently in trials to treat NMO. Staff in the Center for Multiple Sclerosis and Autoimmune Neurology conducts research in neuromyelitis optica, multiple sclerosis and related conditions. Mayo Clinic researchers discovered an autoantibody, later known as aquaporin-4 antibody, which is a specific marker for NMO. Testing for this autoantibody can help diagnose NMO at an early stage and distinguish it from multiple sclerosis (MS) and other conditions. PublicationsSee a list of publications about neuromyelitis optica by Mayo Clinic doctors on PubMed, a service of the National Library of Medicine. By Mayo Clinic Staff Neuromyelitis optica care at Mayo Clinic Request an appointment Diagnosis & treatmentCare at Mayo Clinic Nov. 23, 2022 Print Related Associated Procedures Lumbar puncture (spinal tap) MRI Products & Services A Book: Mayo Clinic Guide to Better Vision Neuromyelitis opticaSymptoms&causesDiagnosis&treatmentDoctors&departmentsCare atMayoClinic Research: It's all about patients Show transcript for video Research: It's all about patients [MUSIC PLAYING] Joseph Sirven, M.D., Professor of Neurology, Mayo Clinic: Mayo's mission is about the patient. The patient comes first. So the mission and research here is to advance how we can best help the patient, how to make sure the patient comes first in care. So in many ways, it's a cycle. It can start with as simple as an idea worked on in a laboratory, brought to the patient bedside, and if everything goes right — and let's say it's helpful or beneficial — then brought on as a standard approach. And I think that is one of the unique characteristics of Mayo's approach to research — that patient-centeredness — that really helps to put it in its own spotlight. CON-20375644 Patient Care & Health Information Diseases & Conditions Neuromyelitis optica