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Departments that treat this condition Cardiovascular Medicine Hematology Nephrology and Hypertension Doctors who treat this condition Edit search filters close Narrow your search By location Rochester, MN By last name There are no doctors whose last name begins with the letter A A Find a doctor whose last name begins with the letter B B There are no doctors whose last name begins with the letter C C Find a doctor whose last name begins with the letter D D There are no doctors whose last name begins with the letter E E Find a doctor whose last name begins with the letter F F Find a doctor whose last name begins with the letter G G There are no doctors whose last name begins with the letter H H There are no doctors whose last name begins with the letter I I There are no doctors whose last name begins with the letter J J Find a doctor whose last name begins with the letter K K Find a doctor whose last name begins with the letter L L There are no doctors whose last name begins with the letter M M There are no doctors whose last name begins with the letter N N There are no doctors whose last name begins with the letter O O Find a doctor whose last name begins with the letter P P There are no doctors whose last name begins with the letter Q Q Find a doctor whose last name begins with the letter R R There are no doctors whose last name begins with the letter S S There are no doctors whose last name begins with the letter T T There are no doctors whose last name begins with the letter U U There are no doctors whose last name begins with the letter V V There are no doctors whose last name begins with the letter W W There are no doctors whose last name begins with the letter X X There are no doctors whose last name begins with the letter Y Y active Find a doctor whose last name begins with the letter Z Z Reset all filters Search Tips Use quotes for phrases. Even if there are no auto-suggestions within the search field, hit "Search" anyway, as you may still get results. Displaying 1-1 out of 1 doctors available Last Name Initial: Z Ladan Zand, M.D. Nephrologist Rochester, MN Areas of focus: Vasculitis, Monoclonal gammopathy of undetermined significance, Glomerular disease, Minimal change disease, Focal segme...ntal glomerulosclerosis, IgA nephropathy, Membranous nephropathy, Lupus nephritis, Fibrillary glomerulonephritis, Membranoproliferative glomerulonephritis, Thrombotic microangiopathy Show more areas of focus for Ladan Zand, M.D. ResearchMayo Clinic has been a global leader in research on MGUS, focusing on understanding its biology, risk factors, and progression to multiple myeloma and related plasma cell conditions. Researchers investigate the genetic, molecular and clinical mechanisms underlying MGUS, including chromosomal changes, plasma cell biology and predictors of disease progression. Mayo Clinic investigators also lead long-term observational studies and clinical trials aimed at identifying biomarkers, improving risk stratification and determining when MGUS is likely to progress to symptomatic disease. Their work has helped shape international guidelines for MGUS monitoring and management while advancing precision medicine approaches for plasma cell conditions. Researchers at Mayo Clinic coined the term monoclonal gammopathy of undetermined significance (MGUS) in the 1970s and continue to study this condition. Current research focuses on understanding how risk factors lead to the condition, how these factors might affect treatment, and how to prevent progression to blood cancers and other conditions. Cancer research is conducted in coordination with the Mayo Clinic Comprehensive Cancer Center. Healthcare professionals and scientists at the center are working on improving the diagnosis and treatment of myeloma and other blood conditions. PublicationsSee a list of publications about (MGUS) by Mayo Clinic doctors on PubMed, a service of the National Library of Medicine. Research Profiles Edit search filters close Narrow your search By location Arizona Florida Minnesota View all View all physicians • All Locations Kandasamy, Richard Ph.D. Minnesota Kumar, Shaji M.D. Minnesota Vachon, Celine M. Ph.D. Minnesota By Mayo Clinic Staff Monoclonal gammopathy of undetermined significance (MGUS) care at Mayo Clinic Request an appointment Diagnosis & treatmentCare at Mayo Clinic Sept. 16, 2026 Print Living with monoclonal gammopathy of undetermined significance (MGUS)? Connect with others like you for support and answers to your questions in the Blood Cancers & Disorders support group on Mayo Clinic Connect, a patient community. Blood Cancers & Disorders Discussions My Bone Marrow Transplant (BMT/SCT) story: Will you share yours? 936 Replies Fri, Sep 18, 2026 chevron-right Anyone else have Mantle Cell Lymphoma? 124 Replies Thu, Sep 17, 2026 chevron-right Have you ever had hiccups with or after chemotherapy? 132 Replies Wed, Sep 16, 2026 chevron-right See more discussions Related Associated Procedures Bence-Jones protein test Bone marrow biopsy Complete blood count (CBC) Creatinine test Kappa and lambda free light chain test X-ray Show more associated procedures Products & Services A Book: Mayo Clinic Family Health Book Newsletter: Mayo Clinic Health Letter — Digital Edition Show more products and services from Mayo Clinic Monoclonal gammopathy of undetermined significance (MGUS)Symptoms&causesDiagnosis&treatmentDoctors&departmentsCare atMayoClinic Research: It's all about patients Show transcript for video Research: It's all about patients [MUSIC PLAYING] Joseph Sirven, M.D., Professor of Neurology, Mayo Clinic: Mayo's mission is about the patient. The patient comes first. So the mission and research here is to advance how we can best help the patient, how to make sure the patient comes first in care. So in many ways, it's a cycle. It can start with as simple as an idea worked on in a laboratory, brought to the patient bedside, and if everything goes right — and let's say it's helpful or beneficial — then brought on as a standard approach. And I think that is one of the unique characteristics of Mayo's approach to research — that patient-centeredness — that really helps to put it in its own spotlight. CON-20166978 Diseases & Conditions Monoclonal gammopathy of undetermined significance (MGUS)