Print Overview Enlarge image Close Hydronephrosis Hydronephrosis Hydronephrosis happens when urine builds up in a kidney. Often, a blockage called an obstruction in the upper part of the urinary tract causes the buildup. Kidney swelling can result. This causes the part of the kidney called the renal pelvis to bulge, or become distended. It could lead to kidney scarring, and the kidney may not work as well as it should. Hydronephrosis is swelling of one or both kidneys. It happens when urine can't drain from a kidney and builds up in the kidney as a result. The condition can be due to a blockage in the tubes that drain urine from the kidneys. It also can happen due to a difference present at birth that prevents urine from draining properly. In some people, hydronephrosis causes kidney damage over time. Hydronephrosis can happen at any age. The condition often causes no symptoms. People who get symptoms may have side and back pain, painful urination, vomiting and fever. Healthcare professionals have various ways to spot hydronephrosis. Tests to find the condition can be done during infancy or sometimes before a baby is born. Treatment for hydronephrosis depends on the condition's cause. Some people need medicine or surgery to feel better and prevent kidney damage. Mild hydronephrosis sometimes goes away on its own over time.Products & ServicesA Book: Mayo Clinic Family Health Book SymptomsHydronephrosis often causes no symptoms. But when symptoms happen, they can include: Pain in the side and back that may travel to the lower stomach area or groin. Pain with urination, or feeling a need to urinate that is urgent or happens often. Upset stomach and vomiting. Fever. Failure to thrive in infants. Weight loss or loss of appetite. Blood in urine. When to see a doctorCall your healthcare professional if you have any symptoms of hydronephrosis. Babies with the condition often don't have symptoms. But get your baby a healthcare checkup right away for symptoms such as high fever. Request an appointment Risk factorsHydronephrosis risk factors among adults ages 20 to 60 include being born female. The higher risk could be due to certain conditions that affect the uterus, such as pregnancy. It also could be due to conditions that affect the ovaries, such as cysts, buildups of pus and cancer. Risk factors for people older than age 60 include having an enlarged prostate or a urinary tract blockage from cancer. ComplicationsHydronephrosis can lead to other health conditions called complications. Without treatment, some people who have severe hydronephrosis develop lasting kidney damage. Rarely, the condition can cause an affected kidney to lose its ability to filter blood, also called kidney failure. By Mayo Clinic Staff Request an appointment Diagnosis & treatment Nov. 06, 2024 Print Show references AskMayoExpert. Hydronephrosis (nonstone related) (adult). Mayo Clinic; 2023. Hydronephrosis. National Kidney Foundation. https://www.kidney.org/atoz/content/hydronephrosis. Accessed June 10, 2024. Ferri FF. Hydronephrosis. In: Ferri's Clinical Advisor 2025. Elsevier; 2025. https://www.clinicalkey.com. Accessed June 10, 2024. Zeidel ML, et al. Clinical manifestations and diagnosis of urinary tract obstruction (UTO) and hydronephrosis. https://www.uptodate.com/contents/search. Accessed Nov. 12, 2019. Hydronephrosis. National Health Service. https://www.nhs.uk/conditions/hydronephrosis/. Accessed June 10, 2024. Related Hydronephrosis Products & Services A Book: Mayo Clinic Family Health Book HydronephrosisSymptoms&causesDiagnosis&treatmentDoctors&departments Advertisement Mayo Clinic does not endorse companies or products. Advertising revenue supports our not-for-profit mission. Advertising & Sponsorship Policy Opportunities Ad Choices Mayo Clinic Press Check out these best-sellers and special offers on books and newsletters from Mayo Clinic Press. NEW: Mayo Clinic Guide to Better Sleep Listen to Health Matters Podcast Mayo Clinic on Incontinence The Essential Diabetes Book FREE Mayo Clinic Diet Assessment Mayo Clinic Health Letter - FREE book CON-20357565 Patient Care & Health Information Diseases & Conditions Hydronephrosis