Radiology

Below are current clinical trials.

Filter this list of studies by location, status and more.

1. A Study to Investigate the Use of Diaphragm Muscle Ultrasound to Assess the Duration of a Diaphragm Nerve Block

   Rochester, Minn.

   The purpose of this study is to to determine the impact of anesthesia (liposomal bupivacaine) on diaphragm muscle forces using a non-invasive ultrasonographic shear wave elastography (SWE) method.  

2. A Study to Evaluate Shared Decision Making for Patients with Minor Head Injury

   Rochester, Minn.

   The primary purpose of this study is to understand the effect of educating patients and encouraging shared decision making on rates of CT scanning in head injured patients by using an already developed app and observing the effect on the health care provider

    

3. A Study to Assess an MRI Image Localizer for 7T MRI Neuronavigation

   Rochester, Minn.

   The purpose of this study is to develop a localizer for use within the 7T MRI to allow for future clinical use in neurosurgical planning.

4. A Study to Evaluate the Safety, Pharmacokinetics and Biodistribution of an Imaging Agent, 18F-OP-801 (18F Hydroxyl Dendrimer) in Patients With Amyotrophic Lateral Sclerosis (ALS) and Healthy Volunteers (HV)

   Jacksonville, Fla.

   The purpose of this study is to evaluate the safety, pharmacokinetics and biodistribution of an imaging agent, 18F-OP-801 (18F Hydroxyl Dendrimer), after intravenous administration to patients with Amyotrophic Lateral Sclerosis (ALS) and Healthy Volunteers (HV)

5. A Study to Evaluate Screening Contrast Enhanced Digital Mammogram (CEDM) in Study Participants at Intermediate Breast Cancer Risk and Polygenic Risk Score (PRS) Results

   Rochester, Minn.

   The purpose of this study is to evaluate a low-cost Contrast Enhanced Digital Mammogram (CEDM) protocol as a supplemental screening method to standard mammographic screening in women at intermediate lifetime-risk (and not undergoing annual MR surveillance) for breast cancer.

    

    

    

    

6. A Study of Demyelinating Lesions as a Cause of Progressive Motor Deterioration

   Rochester, Minn.

   The purpose of this study is a comprehensive review of the clinical and radiologic history in these patients as well as review of neuropathology in deceased patients, where available.  The goal of this research is to investigate the hypothesis that this presentation represents a spatially limited form of CNS inflammatory demyelinating disease.

7. Determinants of Incident Stroke Cognitive Outcomes and Vascular Effects on Recovery (DISCOVERY)

   Rochester, Minn.

   The purpose o fthis study

   A total of 8,000 patients presenting to CPSs with acute-onset AIS, ICH or aSAH and no history of dementia will be enrolled within 6 weeks of stroke onset.

   All participants will undergo baseline screening for evidence of pre-stroke dementia. Those who pass baseline screening will complete a blood draw and a series of cognitive and functional assessments at baseline.

   Participants will undergo in-person (3-6 months, 18 months) and telephone (annual) follow-up visits for the duration of the study to assess for longitudinal cognitive and functional outcomes. In addition to Tier 1 procedures, at each in-person follow-up visit: Tier 2 participants will also undergo MRI scanning, comprehensive cognitive assessment batteries and longitudinal blood collection; and Tier 3 participants will also complete amyloid- and tau-PET/CT scans.

8. A Study to Predict Sepsis-Associated Acute Kidney Injury by Assessing Renal Microvascular Blood Flow and Elasticity with Contrast-Enhanced Ultrasonography and Ultrasound Elastogram

   Rochester, Minn.

   The purpose of this study is to assess kidney microcirculation using contrast-enhanced ultrasonography associated with kidney ultrasound elastography among patients who are at risk of sepsis-associated acute kidney injury provides strong predictive ability for AKI and potential therapeutic targets. 

    

9. Improving the Quality of Magnetic Resonance Imaging (MRI) Examinations

   Rochester, Minn.

   The purpose of this research study is to improve the quality of Magnetic Resonance Imaging (MRI) examinations.

10. A Study to Compare Two Ultrasound-based Methods for Assessing Diaphragm Muscle Function

    Rochester, Minn.

    The purpose of this study is to assess and compare the utility of ultrasonographic shear wave elastography (SWE) method as compared to “ABCDE” thickening ratio and fraction method in assessing diaphragm function.