Psychiatry and Psychology

Below are current clinical trials.

Filter this list of studies by location, status and more.

1. Attitudes and Beliefs About Gene Transfer Therapy in Adults with Cocaine Use Disorder

   Rochester, Minn.

   The purpose of this study is to investigate the facilitators and barriers of adults with a history of cocaine use disorder (CocUD) in sustained remission to participating in a Phase I gene transfer study aimed at reducing the rate of cocaine relapse. 

2. A Study to Build Translational Science through an Online Social Media Community Partnership Among Minnesota Communities, the CTSA Community Engagement Programs at Mayo Clinic and the University of Minnesota

   Rochester, Minn.

   The purpose of this study is to develop and pilot a novel community-engaged communication network statewide in Minnesota through social media; to assess community knowledge, attitudes, and perceptions of ongoing and completed research, and to increase access to information about and participation in research. 

3. Brain Health and Dementia Prevention Registry

   Jacksonville, Fla.

   The purpose of this study is to create a registry of patients having a clinical diagnosis and collect demographics, cognitive testing, blood and cerebrospinal fluid so that biomarkers and genetic difference can be found in different patient groups.

4. Happigenius Social-Emotional Learning Curriculum in Rochester Public Schools

   Rochester, Minn.

   The purpose of this study is to test the effectiveness of HappiGenius curriculum in 3rd grade students attending elementary school in the Rochester Public Schools system (Rochester, MN). Convenience samples are selected from students in classrooms receiving the HappiGenius curriculum in their normal school curriculum and students in classrooms that have opted not to have HappiGenius in their classroom this term. For the study, questionnaires will be administered at the start and conclusion of HappiGenius lessons to determine whether HappiGenius curriculum delivers the core competencies of improved attention, positive affect, self-awareness, sociality, and self-kindness.

5. A Study to Evaluate the Effectiveness of Psychological Support Based on Positive Suggestions on Mental Health Morbidity and Cognitive Function

   Rochester, Minn.

   The purpose of this trial is to compare the effectiveness of psychological support based on positive suggestions (PSBPS) vs. usual care on mental health morbidity and cognitive function in survivors of critical illness.

6. A Study to Evaluate the Safety, Tolerability and Effectiveness of V117957 in Subjects with Insomnia Associated with Alcohol Cessation

   Rochester, Minn.

   The purpose of this study is to evaluate the safety, tolerability and effectiveness of V117957, compared to placebo, in subjects with alcohol use disorder (AUD) who experience insomnia associated with alcohol cessation.

7. A Study to Evaluate Prevalence of Secondary Adrenal Insufficiency in Patients with Chronic Pain

   Jacksonville, Fla.

   The purpose of this study is to evaluate the hormonal profile related to opioed induced adrenal insufficency (OIAI) in chronic pain patients that completed the 3-weeks Interdisciplinary Pain Rehabilitaion Program (IPRP) at the Pain Rehabilitation Center (PRC) at Mayo Clinic / Florida.

8. A Study to Evaluate the Prevalence and Impact of Eating Disorders Among Patients with Inflammatory Bowel Disease

   Jacksonville, Fla.

   The purpose of this study is to assess the prevalence of eating disorders; specifically, Avoidant/Restrictive Food Intake Disorder (ARFID) among adult patients in the IBD clinic and compare to the patient population seen in the primary care clinics at Mayo Clinic Florida.

9. A Study to Analyse the Genetic Makeup of Those with Opioid and Substance Use Disorders

   Albert Lea, Minn., Rochester, Minn.

   The purpose of this study is to establish an opioid and multiple addiction (OMA) biobank that creates a comprehensive standard patient phenotype using standardized subjective assessments and objective behavioral measurements for future research. 

10. Treating Negative Affect in Low Back Pain Patients (TNA-LBP)

    Rochester, Minn.

    The purpose of this study is to compare the effectiveness of combination therapy with antidepressants (AD), fear avoidance rehabilitation (EFAR) AD+EFAR vs. each treatment alone to improve pain, self-reported function, depression, and anxiety in patients with chronic low back pain and high negative affect.