Pain Medicine

Below are current clinical trials.

Filter this list of studies by location, status and more.

1. Analysis of Orthobiologic Agents (OBA) for Painful Musculoskeletal Conditions and Tissue Regeneration

   Jacksonville, Fla.

   The objectives of this study are to determine the effect of patient factors and manufacturing procedures on OBA product characteristics, to assess the clinical outcomes of patients affected by multiple painful musculoskeletal disorders and tissue regeneration needs that are treated with guided procedures in the Mayo Clinic Pain practice, to assess genetic and epigenetic factors associated to multiple painful musculoskeletal disorders and tissue regeneration needs, to determine the effect of OBA characteristics on patient outcomes for patients treated with OBA procedures, including a reference group of patients not receiving OBAs as part of their medical care.

2. A Study to Evaluate Analgesic Use and Duration for Pediatric Long Bone Fractures

   Rochester, Minn.

   The purpose of this study is to develop an evidenced-based guideline for pediatric opioid prescribing guideline from the emergency department for long bone fractures to more closely tailor pain management to abuse potential. 

3. A Study to Investigate the Use of Diaphragm Muscle Ultrasound to Assess the Duration of a Diaphragm Nerve Block

   Rochester, Minn.

   The purpose of this study is to to determine the impact of anesthesia (liposomal bupivacaine) on diaphragm muscle forces using a non-invasive ultrasonographic shear wave elastography (SWE) method.  

4. A Study to Evaluate Prevalence of Secondary Adrenal Insufficiency in Patients with Chronic Pain

   Jacksonville, Fla.

   The purpose of this study is to evaluate the hormonal profile related to opioed induced adrenal insufficency (OIAI) in chronic pain patients that completed the 3-weeks Interdisciplinary Pain Rehabilitaion Program (IPRP) at the Pain Rehabilitation Center (PRC) at Mayo Clinic / Florida.

5. Treating Negative Affect in Low Back Pain Patients (TNA-LBP)

   Rochester, Minn.

   The purpose of this study is to compare the effectiveness of combination therapy with antidepressants (AD), fear avoidance rehabilitation (EFAR) AD+EFAR vs. each treatment alone to improve pain, self-reported function, depression, and anxiety in patients with chronic low back pain and high negative affect.

    

    

6. Pediatric Pain Rehabilitation Treatment Outcomes for Chronic Noncancer Pain

   Rochester, Minn.

   The purpose of the study is to learn more about adolescent and young adults' experience with chronic pain. In particular, we are studying factors which lead to pain-associated disability and factors which predict decreased disability during and after participation in a three-week intensive treatment program. In addition to gathering information from the young people with chronic pain, parents are also asked to give their perspective.

    

7. Evaluating Patterns of and Changes in Hair Cortisol Levels in Pediatric Patients With Chronic Pain

   Rochester, Minn.

   The purpose of this study is to evaluate patterns of and changes in secretion levels of the stress hormone, cortisol and other steroid hormones (i.e. DHEA, testosterone, progesterone) from hair samples of 150 pediatric patients with chronic pain and a parent or caregiver upon admission and at 3 and 6 months after participation in Mayo Clinic’s intensive, interdisciplinary pediatric pain treatment program.