Clinical Genomics

Mayo Clinic's Connective Tissue Disorder Clinic diagnoses and coordinates care for people affected with inherited or genetic forms of connective tissue disease, such as:

• Ehlers-Danlos syndrome.
• Loeys-Dietz syndrome.
• Marfan syndrome.
• Thoracic aortic aneurysm and aortic dissection.

If clinical findings — such as loose skin, joint hypermobility, vascular aneurysms — or family history indicates a connective tissue disorder, additional evaluation by a geneticist is appropriate.

Other subspecialties involved in Mayo Clinic's Connective Tissue Disorder Clinic include physical medicine and rehabilitation, pain rehabilitation and others as needed. Our team of experts works together to provide individualized care to meet each person's unique needs.