Nephrology and Hypertension

Below are current clinical trials.

Filter this list of studies by location, status and more.

1. A Study to Assess Palliative Care Impact on Patients with End-stage Renal Disease

   Jacksonville, Fla.

   The purpose of this study is to evaluate the impact of palliative care consultations on quality of life and advance care planning in end-stage renal disease patients on hemodialysis, evaluate hemodialysis patients’ and caregivers’ satisfaction with palliative care consultations, and to compare quality of life and advance directive completion in dialysis patients who have and have not received palliative care consultations.

2. Prospective Research Rare Kidney Stones

   Rochester, Minn., Jacksonville, Fla.

   The purpose of this study is to determine the natural history of the hereditary forms of nephrolithiasis and chronic kidney disease (CKD), primary hyperoxaluria (PH), cystinuria, Dent disease and adenine phosphoribosyltransferase deficiency (APRTd) and acquired enteric hyperoxaluria (EH). The investigator will measure blood and urinary markers of inflammation and determine relationship to the disease course. Cross-comparisons among the disorders will allow us to better evaluate mechanisms of renal dysfunction in these disorders.

3. A Study to Assess Reproductive History in Kidney Donors

   Rochester, Minn., Scottsdale/Phoenix, Ariz.

   The purpose of this study is to analyze the effect of parity, menopause and reproductive lifespan on kidney structure and function.

4. 24-Hydroxylase Deficiency and CYP24A1 Mutation Patient Registry

   Rochester, Minn.

   You are being asked to take part in this research registry because you or your family member is suspected to have a 24-hydroxylase deficiency.

5. A Study to Promote Shared Decision Making of Treatment Choices in Patients who have Advanced Kidney Disease

   Rochester, Minn., Scottsdale/Phoenix, Ariz.

   The purpose of this study is to develop educational materials that will help patients and clinicians talk about treatment options for patients with advanced kidney disease.

6. A Study to Evaluate the Nrf2 Response in Patients with Autosomal Dominant Polycystic Kidney Disease (ADPKD)

   Rochester, Minn.

   The purpose of this study is to determine whether patients with ADPKD present with abnormal levels of fumarate that correlates with disease severity and this increase in fumarate results in upregulation of Nrf2 signaling leading to increased cellular proliferation and contributing to cystogenesis.

7. Tissue and Blood Registry for Individuals with Liver and Biliary Tumors

   Jacksonville, Fla.

   This study will collect and store samples of tissue and blood for current and future research studies on Liver and Biliary Tumors.

8. Biospecimens Resource for Glomerular and Tubulo-interstitial Diseases

   Rochester, Minn.

   This study is being done to create a "resource" of samples that can be used to improve our ability to diagnose and treat MN, IgAN, MPGN, FSGS/MCD, Lupus Nephritis, AAV, other glomerular tubulo-interstitial disease.

9. Predictive Role of Non-Invasive Glucose Assessment During Pregnancy

   Rochester, Minn.

   This study aims to determine the value of regular, non-invasive [glucose] LabClasp monitoring during pregnancy.

10. A Study to Compare Urinary Exosomes in Healthy Kidney Donors and Renal Transplant Recipients

    Rochester, Minn.

    The purpose of this study is to use urinary exosomes to non-invasively identify (protein biomarkers) various conditions affecting the renal transplant.