Clinical trials Below are current clinical trials.90 studies in Cardiovascular Medicine (open studies only). Filter this list of studies by location, status and more. A Study to Evaluate the Burden of Treatment and Illness in Advanced Heart Failure Patients Rochester, Minn. The primary purpose of this study is to identify which aspects of treatment are most prevalent and burdensome to patients with advanced heart failure. Spontaneous Coronary Artery Dissection: Mechanistic Evaluation Rochester, Minn. The purpose of this study is to screen for unique or characteristic circulating peptides, hormonal biomarkers and circulating mRNA in patients who have experienced spontaneous coronary artery dissection (SCAD). A Study to Analyze Association of Frequent Premature Ventricular Complex with Stroke or Transient Ischemic Attack Rochester, Minn. The purpose of this study is to verify that high Premature Ventricular Complex (PVC) burden is associated with increased risk of stroke and/or Transient Ischemic Attack (TIA), to examine outcomes such as stroke/TIA, atrial fibrillation/flutter, and all-cause mortality associated with PVCs, and to evaluate whether PVCs are associated with development of appendage dysfunction. Bioengineered Cardiac Tissue for Hypoplastic Left Heart Syndrome Analysis Rochester, Minn. The purpose of this study is to produce and characterize patient-specific cardiac tissue for Hypoplastic Left Heart Syndrome (HLHS) using reprogrammed cell technology. Predictive Role of Non-Invasive Glucose Assessment During Pregnancy Rochester, Minn. This study aims to determine the value of regular, non-invasive [glucose] LabClasp monitoring during pregnancy. Expanded Access Protocol of Patisiran for Patients With Hereditary ATTR Amyloidosis (hATTR) Rochester, Minn. The purpose of this study is to provide expanded access of patisiran to patients with hereditary transthyretin-mediated amyloidosis (hATTR). A Study to Assess Non-invasive Arterial Air Plethysmography of Normal and Abnormal Arterial Hemodynamics Rochester, Minn. The purpose of this study is to determine the accuracy (sensitivity, specificity, negative predictive value, positive predictive value) of a non-invasive arterial air plethysmography prototype in people with normal and abnormal arterial hemodynamics. A Study to Evaluate Exercise Capacity and Positive Airway Pressure Impact on Sleep Apnea in Heart Failure Rochester, Minn. The purpose of this study is to determine the prevalence of Obstructive Sleep Apnea (OSA) in HFpEF, and its clinical and hemodynamic correlates, and to determine the impact of intervention with CPAP therapy on exercise capacity and quality of life in HFpEF patients with OSA. the Mayo Cardiac Sarcoid Registry Rochester, Minn., Jacksonville, Fla. Aims, purpose, or objectives: Develop a retrospective registry of patients with cardiac sarcoidosis Develop a prospective registry of patients with cardiac sarcoidosis Understand the natural history of cardiac sarcoidosis through evaluation of outcomes of patients in the registry Determine risk factors for sarcoid involvement of the heart Evaluate outcomes of patients both treated and untreated with cardiac sarcoidosis Understand the complications of untreated and treated cardiac sarcoidosis (FMD Impact Registry) Fibromuscular Dysplasia Findings and Outcomes Rochester, Minn. To describe the clinical, laboratory, pathologic, imaging findings, therapy and outcomes in all patients with Fibromuscular Dysplasia (FMD) and/or segmental arterial mediolysis evaluated at Mayo Clinic retrospectively (back to 01/01/1990) and prospectively (starting 04/13/2016). 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So the mission and research here is to advance how we can best help the patient, how to make sure the patient comes first in care. So in many ways, it's a cycle. It can start with as simple as an idea worked on in a laboratory, brought to the patient bedside, and if everything goes right — and let's say it's helpful or beneficial — then brought on as a standard approach. And I think that is one of the unique characteristics of Mayo's approach to research — that patient-centeredness — that really helps to put it in its own spotlight. SectionsRequest an appointmentOverviewTests & proceduresConditions treatedDoctorsSpecialty groupsExpertise & rankingsClinical trialsResearchPatient storiesCosts & insuranceNews from Mayo ClinicReferrals ORG-20121929 Medical Departments & Centers Cardiovascular Medicine