Research

Mayo Clinic fosters a robust research environment in which scientific expertise is combined with clinical insights to create solutions for unmet patient needs. The unrelenting focus of our physician-researchers and other scientists results in advancements in the diagnosis and treatment of breast cancer and other breast conditions.

Breast research at Mayo Clinic is conducted along a wide spectrum, from individual laboratories of principal investigators to large-scale world-renowned programs and centers, including Mayo Clinic Comprehensive Cancer Center, which is designated as a comprehensive cancer center by the National Cancer Institute and boasts broad geographic reach through its campuses in Phoenix/Scottsdale, Arizona; Jacksonville, Florida; and Rochester, Minnesota.

Our breast research is improving lives by:

  • Advancing breast cancer research with cryoelectron microscopy.
  • Identifying hereditary genes and mutations that predispose people to cancer.
  • Advancing the development of drug targets and treatment strategies for people with triple-negative breast cancer.
  • Developing measles virus-based immune therapy to treat metastatic breast cancer.
  • Studying the effectiveness of aromatase inhibitors in suppressing estrogen and preventing breast cancer recurrence.
  • Developing new therapeutics for endocrine-resistant breast cancer.

Advanced Clinical Trials and Translational Sciences Research Program

The Advanced Clinical Trials and Translational Sciences Research Program conducts research across many cancer types. This includes breast and gynecologic cancers, genitourinary cancers, gastrointestinal cancers, hematologic malignancies, neuro-oncology, lung cancer, head and neck cancer, pediatric cancer, and rare cancers such as endocrine cancer, melanoma and sarcoma.

Mayo Clinic Breast Cancer SPORE

The Breast Cancer Specialized Program of Research Emphasis (SPORE) supports translational breast cancer research that can be quickly applied to clinical practice. Its goal is to give patients access to better treatment options and care. The breast cancer SPORE also funds innovative

Mayo Mammography Health Study

The Mayo Mammography Health Study at Mayo Clinic is a breast cancer research study with the goal of identifying features on mammograms that can be used to help detect which people are at high risk of developing breast cancer.

Clinical trials

Mayo Clinic researchers are involved in studies to evaluate potential treatments for many conditions and treatments, including breast cancer, chemotherapy, hormonal treatments, targeted biological therapies, radiation therapy, prevention of breast cancer, management of hot flashes, and treatment-related fatigue, nausea and cognitive dysfunction. These types of studies are called clinical trials. Our researchers carry out hundreds of clinical trials in all phases.

You may have the opportunity to participate in clinical trials, whether you're newly diagnosed with breast cancer or living with recurrent or advanced breast cancer. Ask your healthcare professional about clinical trials that might be right for you.

Learn more about clinical trials at Mayo Clinic.

Dec. 21, 2024