Clinical trials Below are current clinical trials.16 studies in Anesthesiology and Perioperative Medicine (open studies only). Filter this list of studies by location, status and more. A Study to Evaluate Prevalence of Hypogonadism in Patients with Chronic Pain Jacksonville, Fla. The purpose of this study is to evaluate the hormonal profile related to opioid-induced hypogonadism (OIH) in chronic pain patients before and after completing 3 weeks Interdisciplinary Pain Rehabilitation Program (IPRP) at Pain Rehabilitation Center (PRC) at Mayo Clinic/Florida. Exparel Injection for Postoperative Orbital Pain Rochester, Minn. After surgery to remove the eye, either by enucleation or evisceration, patients have variable levels of pain for several postoperative days. Some patients have almost no discomfort while others require significant amounts of oral narcotics and report pain of 10 out of 10 on a numerical rating scale. The current operative standard is to infiltrate the eye socket with 0.5% bupivacaine during surgery leading to several hours of postoperative analgesia. In 2011, Pacira Pharmaceuticals released a bupivacaine liposomal injectable suspension (Exparel, 1.3%) which offers sustained release of bupivacaine giving postoperative pain control for up to 72 hours. This medication has been used in numerous surgeries including inguinal hernia repair, hemorrhoidectomy, bunionectomy, breast reconstruction, and orthopedic surgery, and the literature reports improved pain control, decreased use of oral opioids, and increased patient satisfaction. There are no reports of the use of Exparel in the ophthalmic literature. The investigators propose a randomized, controlled trial to compare the postoperative pain control offered by sustained release bupivacaine to that offered by standard plain bupivacaine after enucleation or evisceration. A Study to Analyze the Effects of Buprenorphine on Hyperalgesia in Patients with Opioid Use Disorder Rochester, Minn. The purpose of this study is to investigate the effects of buprenorphine on hyperalgesia (HP) perception in adults undergoing treatment for opioid use disorder (OUD). Tobacco Dependence Intervention Knowledge, Practices, and Attitudes among Registered Nurses Rochester, Minn. The specific aim of this study is to determine if the implementation of a tobacco dependence intervention, among registered nurses on Gonda 7 caring for ambulatory surgical patients, results in a change in the knowledge, practices, and attitudes of patient tobacco use assessment as compared to baseline. A Study to Evaluate Time to First Movement for Fetal Surgery Patients Injected with Intramuscular Anesthesia Rochester, Minn. The purpose of this study is to determine the time from intramuscular injection to the time of first fetal movement after a fetal surgery procedure. A Study to Evaluate AAV8-human Cocaine Hydrolase to Treat Cocaine Use Disorder Rochester, Minn. The purpose of this study is to see if an experimental agent, when given to subjects who wish to abstain from cocaine, will decrease their craving for cocaine and prevent them from relapsing and returning to cocaine use. This experimental agent is called AAV8-hCocH; and it is a gene modified viral vector. We want to determine the safety of its use in adults who have a cocaine use disorder in sustained remission. A Study of Serum Baclofen Levels in Patients with Intrathecal Baclofen Therapy Rochester, Minn. The purpose of this study is to determine serum levels of baclofen in patients with spasticity managed with long-term intrathecal baclofen therapy. Response of Continuous Recombinant Antithrombin Infusion in Postcardiotomy ECMO Patients Rochester, Minn. The objective of this study will be to prospectively evaluate the response of a continuous infusion of recombinant human antithrombin concentrate (rhAT) (ATRYN®) to achieve and maintain the AT activity within a specified range in adult patients that require extracorporeal membrane oxygenation (ECMO) following cardiopulmonary bypass (CPB) and cardiac surgery. A Study to Assess Opioid-Induced Respiratory Depression Using Diaphragm Muscle Shear Wave Elastography Rochester, Minn. The purpose of this study is to determine the impact of opioid administration on diaphragm muscle forces during resting breathing and during higher force maneuvers by using a non-invasive shear wave elastography (SWE) method. Text Messaging Smoking Cessation Program in Surgical Patients Rochester, Minn. The goal of this study is to evaluate using a text messaging smoking cessation service in surgical patients during the perioperative period (before scheduled surgery and for 4 weeks post-operatively). Pagination Clinical studies Go to page 11 Go to page 22 NextNext Page Expertise & rankingsResearch Feb. 06, 2024 Share on: FacebookTwitter Anesthesiology and Perioperative MedicineDepartmenthomeSectionsOverviewDoctorsSpecialty groupsExpertise & rankingsClinical trialsResearchNews from Mayo ClinicReferrals Research: It's all about patients Show transcript for video Research: It's all about patients [MUSIC PLAYING] Joseph Sirven, M.D., Professor of Neurology, Mayo Clinic: Mayo's mission is about the patient. The patient comes first. So the mission and research here is to advance how we can best help the patient, how to make sure the patient comes first in care. So in many ways, it's a cycle. It can start with as simple as an idea worked on in a laboratory, brought to the patient bedside, and if everything goes right — and let's say it's helpful or beneficial — then brought on as a standard approach. And I think that is one of the unique characteristics of Mayo's approach to research — that patient-centeredness — that really helps to put it in its own spotlight. SectionsOverviewDoctorsSpecialty groupsExpertise & rankingsClinical trialsResearchNews from Mayo ClinicReferrals ORG-20507824 Medical Departments & Centers Anesthesiology and Perioperative Medicine