Publications Print Jazieh K, Tsai J, Solomon S, Zhu M, Sinicrope FA, Pedersen KS, Fernandez-Zapico ME, Xie H. Identification of Candidate Alterations Mediating KRASG12C Inhibitor Resistance in Advanced Colorectal and Pancreatic Cancers. Clin Cancer Res. 2025 Mar 3; 31 (5):899-906 View PubMed Eslinger C, Walden D, McGary A, Emiloju O, Ahn D, Sonbol MB, Bekaii-Saab T, Zhu M, Hubbard J, Wu C. Comparison of survival outcomes for patients with Lynch vs non-Lynch syndrome and microsatellite unstable colorectal cancer treated with immunotherapy. Cancer. 2025 Feb 15; 131 (4):e35756 View PubMed Schram AM, Goto K, Kim DW, Macarulla T, Hollebecque A, O'Reilly EM, Ou SI, Rodon J, Rha SY, Nishino K, Duruisseaux M, Park JO, Neuzillet C, Liu SV, Weinberg BA, Cleary JM, Calvo E, Umemoto K, Nagasaka M, Springfeld C, Bekaii-Saab T, O'Kane GM, Opdam F, Reiss KA, Joe AK, Wasserman E, Stalbovskaya V, Ford J, Adeyemi S, Jain L, Jauhari S, Drilon A, eNRGy Investigators. Efficacy of Zenocutuzumab in NRG1 Fusion-Positive Cancer. N Engl J Med. 2025 Feb 6; 392 (6):566-576 View PubMed Jazieh K, Yoon H, Zhu M. Advances in Immunotherapy in Esophagogastric Cancer. Hematol Oncol Clin North Am. 2024 Jun; 38 (3):599-616 Epub 2024 Mar 15 View PubMed Choi D, Gonzalez-Suarez AM, Dumbrava MG, Medlyn M, de Hoyos-Vega JM, Cichocki F, Miller JS, Ding L, Zhu M, Stybayeva G, Gaspar-Maia A, Billadeau DD, Ma WW, Revzin A. Microfluidic Organoid Cultures Derived from Pancreatic Cancer Biopsies for Personalized Testing of Chemotherapy and Immunotherapy. Adv Sci (Weinh). 2024 Feb; 11 (5):e2303088 Epub 2023 Nov 29 View PubMed Zhu M, Taylor WR, Mahoney DW, Then SS, Berger CK, Burger KN, Gonser AM, Doering KA, Xie H, Foote PH, Kaiser MW, Allawi HT, Hubbard JM, Kisiel JB. Plasma Assay of Cell-Free Methylated DNA Markers of Colorectal Cancer: A Tumor-Agnostic Approach to Monitor Recurrence and Response to Anticancer Therapies. Cancers (Basel). 2023 Dec 9; 15 (24) Epub 2023 Dec 09 View PubMed Emiloju OE, Zhu M, Xie H, Jin Z, Sinicrope FA, Hubbard JM. Selecting Optimal First-Line Treatment for Microsatellite Stable and Non-Mutated RAS/BRAF Metastatic Colorectal Cancer. Curr Treat Options Oncol. 2023 Dec; 24 (12):1739-1757 Epub 2023 Nov 15 View PubMed Zhu M, Zhang H, Pedersen KS, Foster NR, Jaszewski BL, Liu X, Hirdler JB, An Z, Bekaii-Saab TS, Halfdanarson TR, Boland PM, Yan Y, Hubbard JH, Ma WW, Yoon HH, Revzin A, Fernandez-Zapico ME, Overman MJ, McWilliams RR, Dong H. Understanding Suboptimal Response to Immune Checkpoint Inhibitors. Adv Biol (Weinh). 2023 Apr; 7 (4):e2101319 Epub 2022 Mar 27 View PubMed Zhu M, Ganesan C, Flanagan S, Yoon HH. Life-threatening "hyper-progression" on immunotherapy revealed as pseudo-progression in DNA mismatch repair deficiency: a case report. J Gastrointest Oncol. 2023 Feb 28; 14 (1):435-441 Epub 2023 Feb 14 View PubMed Wang-Gillam A, Lim KH, McWilliams R, Suresh R, Lockhart AC, Brown A, Breden M, Belle JI, Herndon J, Bogner SJ, Pedersen K, Tan B, Boice N, Acharya A, Abdiannia M, Gao F, Yoon HH, Zhu M, Trikalinos NA, Ratner L, Aranha O, Hawkins WG, Herzog BH, DeNardo DG. Defactinib, Pembrolizumab, and Gemcitabine in Patients with Advanced Treatment Refractory Pancreatic Cancer: A Phase I Dose Escalation and Expansion Study. Clin Cancer Res. 2022 Dec 15; 28 (24):5254-5262 View PubMed Hogenson TL, Xie H, Phillips WJ, Toruner MD, Li JJ, Horn IP, Kennedy DJ, Almada LL, Marks DL, Carr RM, Toruner M, Sigafoos AN, Koenig-Kappes AN, Olson RL, Tolosa EJ, Zhang C, Li H, Doles JD, Bleeker J, Barrett MT, Boyum JH, Kipp BR, Mahipal A, Hubbard JM, Scheffler Hanson TJ, Petersen GM, Dasari S, Oberg AL, Truty MJ, Graham RP, Levy MJ, Zhu M, Billadeau DD, Adjei AA, Dusetti N, Iovanna JL, Bekaii-Saab TS, Ma WW, Fernandez-Zapico ME. Culture media composition influences patient-derived organoid ability to predict therapeutic responses in gastrointestinal cancers. JCI Insight. 2022 Nov 22; 7 (22) View PubMed Zhu M, Chen C, Foster NR, Hartley C, Mounajjed T, Salomao MA, Fruth BF, Beamer SE, Kim Y, Harrington SM, Pitot HC, Sanhueza CT, Feng Y, Herrmann J, McWilliams RR, Lucien F, Huang BQ, Ma WW, Bekaii-Saab TS, Dong H, Wigle D, Ahn DH, Hallemeier CL, Blackmon S, Yoon HH. Pembrolizumab in Combination with Neoadjuvant Chemoradiotherapy for Patients with Resectable Adenocarcinoma of the Gastroesophageal Junction. Clin Cancer Res. 2022 Jul 15; 28 (14):3021-3031 View PubMed Zhu M, Bekaii-Saab T. Update to "Homologous Recombination Repair Defect May Predict Treatment Response to Peptide Receptor Radionuclide Therapy for Neuroendocrine Tumors". Oncologist 2022 Jun 8; 27 (6):e534-e535 View PubMed Zhu M, Bekaii-Saab TS. Acquired Immunotherapy Resistance in Gastrointestinal Cancers. JAMA Netw Open 2022 Mar 1; 5 (3):e224646 Epub 2022 Mar 01 View PubMed Zhu M, Costello BA, Yin J, Pettinger AM, Strosberg JR, Erlichman C, Hobday TJ. Phase II Trial of Bevacizumab Monotherapy in Pancreatic Neuroendocrine Tumors. Pancreas. 2021 Nov-Dec 01; 50(10):1435-1439. View PubMed Zhu M, Sorenson KR, Liu R, Gould Rothberg BE, Halfdanarson TR. Biomarkers for prognosis in pancreatic neuroendocrine tumors. Endocr Relat Cancer. 2021 Oct 19; 28 (12):773-782 View PubMed Li JJ, Zhu M, Kashyap PC, Chia N, Tran NH, McWilliams RR, Bekaii-Saab TS, Ma WW. The role of microbiome in pancreatic cancer. Cancer Metastasis Rev. 2021 Sep; 40 (3):777-789 Epub 2021 Aug 28 View PubMed Ma WW, Zhu M, Lam ET, Diamond JR, Dy GK, Fisher GA, Goff LW, Alberts S, Bui LA, Sanghal A, Kothekar M, Khopade A, Chimote G, Faulkner R, Eckhardt SG, Adjei AA, Jimeno A. A phase I pharmacokinetic and safety study of Paclitaxel Injection Concentrate for Nano-dispersion (PICN) alone and in combination with carboplatin in patients with advanced solid malignancies and biliary tract cancers. Cancer Chemother Pharmacol. 2021 Jun; 87 (6):779-788 Epub 2021 Feb 26 View PubMed Zhu M, Sonbol MB, Yoon HH. Trifluridine/tipiracil plus ramucirumab in gastric cancer. Lancet Gastroenterol Hepatol 2021 Mar; 6 (3):154-155 Epub 2021 Jan 26 View PubMed Zhu M, Jin Z, Hubbard JM. Management of Non-Colorectal Digestive Cancers with Microsatellite Instability. Cancers (Basel). 2021 Feb 6; 13 (4) Epub 2021 Feb 06 View PubMed Zhu M, Molina JR, Dy GK, Croghan GA, Qi Y, Glockner J, Hanson LJ, Roos MM, Tan AD, Adjei AA. A phase I study of the VEGFR kinase inhibitor vatalanib in combination with the mTOR inhibitor, everolimus, in patients with advanced solid tumors. Invest New Drugs. 2020 Dec; 38 (6):1755-1762 Epub 2020 Apr 24 View PubMed Zhu M, Sonbol MB, Bassam Sonbol M, Halfdanarson T, Hobday T, Ahn D, Ma WW, Bekaii-Saab T. Homologous Recombination Repair Defect May Predict Treatment Response to Peptide Receptor Radionuclide Therapy for Neuroendocrine Tumors. Oncologist. 2020 Aug; 25 (8):e1246-e1248 Epub 2020 July 01 View PubMed Datta R, Zhu M, Han L, Allore H, Quagliarello V, Juthani-Mehta M. Increased Length of Stay Associated With Antibiotic Use in Older Adults With Advanced Cancer Transitioned to Comfort Measures. Am J Hosp Palliat Care. 2020 Jan; 37 (1):27-33 Epub 2019 June 11 View PubMed Datta R, Wang T, Zhu M, Dembry LM, Han L, Allore H, Quagliarello V, Juthani-Mehta M. Antimicrobial therapy for asymptomatic bacteriuria or candiduria in advanced cancer patients transitioning to comfort measures. Infect Control Hosp Epidemiol. 2019 Apr; 40 (4):470-472 Epub 2019 Mar 01 View PubMed Zeeshan A, Zhu M, Elefteriades JA. Immediate Improvement in Severe Mitral Regurgitation After Aortic Valve Replacement for Severe Aortic Insufficiency. Aorta (Stamford). 2016 Jun; 4 (3):91-94 Epub 2016 June 01 View PubMed Zhu M, Lerum MZ, Chen W. How to prepare reproducible, homogeneous, and hydrolytically stable aminosilane-derived layers on silica. Langmuir. 2012 Jan 10; 28 (1):416-23 Epub 2011 Nov 30 View PubMed Sadr N, Zhu M, Osaki T, Kakegawa T, Yang Y, Moretti M, Fukuda J, Khademhosseini A. SAM-based cell transfer to photopatterned hydrogels for microengineering vascular-like structures. Biomaterials. 2011 Oct; 32 (30):7479-90 Epub 2011 July 29 View PubMed Numthuam S, Ginoza T, Zhu M, Suzuki H, Fukuda J. Gold-black micropillar electrodes for microfluidic ELISA of bone metabolic markers. Analyst. 2011 Feb 07; 136(3):456-8. Epub 2010 Nov 18. View PubMed PST-20521035 Home Publications