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Jason R. Young, M.D.

  1. Radiologist
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Publications

  1. Smith KER, Acosta-Medina AA, Dasari S, Ranatunga W, Rech KL, Ravindran A, Young JR, McGarrah PW, Ruan GJ, Zanwar SS, Li JJ, Sartori-Valinotti JC, Snider JN, Witzig TE, Goyal G, Go RS, Abeykoon JP. Personalized Medicine in Histiocytic Disorders: Novel Targets in Patients Without MAPK Alterations. JCO Precis Oncol. 2024 Nov; 8:e2400471 Epub 2024 Nov 22
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  2. Nathoo N, Uhm JH, Porter AB, Hammack J, Jaeckle KA, Mrugala MM, Crum BA, Flanagan EP, Pittock SJ, Goyal G, Young JR, Koster MJ, Vassallo R, Ryu JH, Davidge-Pitts CJ, Bach C, Ravindran A, Sartori Valinotti JC, Bennani NN, Abeykoon JP, Shah MV, Hook CC, Rech KL, Go RS, Tobin WO, Mayo Clinic-University of Alabama at Birmingham Histiocytosis Working Group. Clinical features and outcomes in primary nervous system histiocytic neoplasms. Blood Cancer J 2024 Jun 20; 14 (1):101 Epub 2024 June 20
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  3. Ruan GJ, Zanwar S, Ravindran A, Schram S, Abeykoon JP, Hazim A, Young JR, Shah MV, Bennani NN, Jiang L, Morlote D, Rech KL, Goyal G, Go RS, Mayo Clinic-University of Alabama at Birmingham Histiocytosis Working Group. Clinical characteristics, molecular aberrations, treatments, and outcomes of malignant histiocytosis. Am J Hematol. 2024 May; 99 (5):871-879 Epub 2024 Feb 26
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  4. Goyal G, Acosta-Medina AA, Abeykoon JP, Dai C, Ravindran A, Vassallo R, Ryu JH, Shah MV, Bennani NN, Young JR, Bach CR, Ruan GJ, Zanwar S, Tobin WO, Koster MJ, Davidge-Pitts CJ, Gruber LM, Dasari S, Rech KL, Go RS. Long-term outcomes among adults with Langerhans cell histiocytosis. Blood Adv. 2023 Nov 14; 7 (21):6568-6578
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  5. Acosta-Medina AA, Kemps PG, Zondag TCE, Abeykoon JP, Forma-Borst J, Steenwijk EC, Feijen EAM, Teepen JC, Bennani NN, Schram SM, Shah MV, Davidge-Pitts C, Koster MJ, Ryu JH, Vassallo R, Tobin WO, Young JR, Dasari S, Rech K, Ravindran A, Cleven AHG, Verdijk RM, van Noesel CJM, Balgobind BV, Bouma GJ, Saeed P, Bramer JAM, de Groen RAL, Vermaat JSP, van de Sande MAJ, Smit EF, Langerak AW, van Wezel T, Tonino SH, van den Bos C, van Laar JAM, Go RS, Goyal G, van Halteren AGS. BRAF V600E is associated with higher incidence of second cancers in adults with Langerhans cell histiocytosis. Blood. 2023 Nov 2; 142 (18):1570-1575
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  6. Bullock C, McCann M, Sharma A, Young JR, Metcalfe AM, Parent EE. FDG PET/CT and thyroid biopsy leads to neurosarcoidosis diagnosis. Radiol Case Rep. 2023 Nov; 18 (11):3932-3935 Epub 2023 Aug 28
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  7. Ravindran A, Dasari S, Ruan GJ, Artymiuk CJ, He R, Viswanatha DS, Abeykoon JP, Zanwar S, Young JR, Goyal G, Go RS, Rech KL, Mayo Clinic-The University of Alabama at Birmingham Histiocytosis Working Group. Malignant Histiocytosis Comprises a Phenotypic Spectrum That Parallels the Lineage Differentiation of Monocytes, Macrophages, Dendritic Cells, and Langerhans Cells. Mod Pathol. 2023 Oct; 36 (10):100268 Epub 2023 July 04
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  8. Banks SA, Bhatti MT, Go RS, Abeykoon JP, Acosta-Medina AA, Hazim AZ, Goyal G, Young JR, Koster MJ, Vassallo R, Ryu JH, Davidge-Pitts CJ, Ravindran A, Sartori Valinotti JC, Bennani NN, Shah MV, Rech KL, Garrity JA, Tobin WO. Reply. Ophthalmology 2023 Sep; 130 (9):e33-e34 Epub 2023 June 10
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  9. Breen WG, Young JR, Hathcock MA, Kowalchuk RO, Thorpe MP, Bansal R, Khurana A, Bennani NN, Paludo J, Bisneto JV, Wang Y, Ansell SM, Peterson JL, Johnston PB, Lester SC, Lin Y. Metabolic PET/CT analysis of aggressive Non-Hodgkin lymphoma prior to Axicabtagene Ciloleucel CAR-T infusion: predictors of progressive disease, survival, and toxicity. Blood Cancer J. 2023 Aug 18; 13 (1):127
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  10. Aaroe A, Kurzrock R, Goyal G, Goodman AM, Patel H, Ruan G, Ulaner G, Young J, Li Z, Dustin D, Go RS, Diamond EL, Janku F. Successful treatment of non-Langerhans cell histiocytosis with the MEK inhibitor trametinib: a multicenter analysis. Blood Adv. 2023 Aug 8; 7 (15):3984-3992
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  11. Orciuolo J, Sharma A, Parent EE, Accurso JM, Jain MK, Young JR. Incidental Airway Findings on PET/CT with (18)F-PSMA. J Nucl Med. 2023 Jun; 64 (6):993 Epub 2023 Jan 05
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  12. Banks SA, Sartori Valinotti JC, Go RS, Abeykoon JP, Goyal G, Young JR, Koster MJ, Vassallo R, Ryu JH, Davidge-Pitts CJ, Ravindran A, Bennani NN, Shah MV, Rech KL, Tobin WO, Mayo Clinic-University of Alabama at Birmingham Histiocytosis Working Group and Mayo Clinic Center for Multiple Sclerosis and Autoimmune Neurology. Neurological Manifestations of Histiocytic Disorders. Curr Neurol Neurosci Rep. 2023 Jun; 23 (6):277-286 Epub 2023 May 20
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  13. Chohan KL, Young JR, Lester S, Moustafa MA, Rosenthal A, Tun HW, Hoppe BS, Johnston PB, Micallef IN, Habermann TM, Ansell SM. End-of-treatment PET in early-stage Hodgkin lymphoma: valuable in addition to interim PET. Haematologica 2023 Jun 1; 108 (6):1697-1701 Epub 2023 June 01
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  14. Chohan KL, Abeykoon JP, Young JR, Tobin WO, Koster MJ, Shah MV, Ryu JH, Vassallo R, Rech KL, Ravindran A, Goyal G, Go RS, Bennani NN. Sirolimus as frontline therapy for PTEN-mutated histiocytic sarcoma. Haematologica. 2023 Jun 1; 108 (6):1702-1706 Epub 2023 June 01
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  15. Kapplinger JD, Lima LMF, Packard AT, Nathan MA, Young JR, Stish BJ, Hough DM. Safety and Efficacy of CT-Guided Percutaneous Biopsy of Suspicious Subcentimeter Pelvic and Retroperitoneal Lymph Nodes Detected by (11)C-Choline PET in Patients With Prostate Cancer. AJR Am J Roentgenol. 2023 May; 220 (5):718-725 Epub 2022 Dec 07
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  16. Quinn E, Olson C, Jain MK, Sullivan J, Thorpe MP, Johnson GB, Young JR. Technologist-Based Implementation of Total Metabolic Tumor Volume into Clinical Practice. J Nucl Med Technol. 2023 Mar; 51 (1):57-59 Epub 2022 Nov 09
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  17. Young JR, Mugu VK, Johnson GB, Ehman EC, Packard AT, Homb AC, Nathan MA, Thanarajasingam G, Kemp BJ. Bayesian penalized likelihood PET reconstruction impact on quantitative metrics in diffuse large B-cell lymphoma. Medicine (Baltimore). 2023 Feb 10; 102 (6):e32665
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  18. Banks SA, Bhatti MT, Go RS, Abeykoon JP, Acosta-Medina AA, Hazim AZ, Goyal G, Young JR, Koster MJ, Vassallo R, Ryu JH, Davidge-Pitts CJ, Ravindran A, Sartori Valinotti JC, Bennani NN, Shah MV, Rech KL, Garrity JA, Tobin WO, Mayo Clinic-University of Alabama at Birmingham Histiocytosis Working Group. Ophthalmologic Involvement in Adults with Histiocytic Disorders: Clinical Presentation and Treatment Outcomes. Ophthalmology. 2023 Jan; 130 (1):77-86 Epub 2022 Aug 03
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  19. Abeykoon JP, Rech KL, Young JR, Ravindran A, Ruan GJ, Dasari S, Morlote DM, King RL, Rummage C, Zanwar S, Acosta-Medina AM, Tobin WO, Shah MV, Bennani NN, Vassallo R, Ryu JH, Koster MJ, Davidge-Pitts CJ, Witzig TE, Goyal G, Go RS, Mayo Clinic-University of Alabama at Birmingham Histiocytosis Working Group. Outcomes After Treatment With Cobimetinib in Patients With Rosai-Dorfman Disease Based on KRAS and MEK Alteration Status. JAMA Oncol. 2022 Dec 1; 8 (12):1816-1820
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  20. Kamboj AK, Agarwal S, Carroll EF, Young JR, Katzka DA. Association of Incidental Positron Emission Tomography Uptake in the Esophagus to Gastroesophageal Reflux Disease. Clin Gastroenterol Hepatol. 2022 Nov; 20 (11):2644-2646.e1 Epub 2021 Sept 03
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  21. Hazim AZ, Acosta-Medina AA, Young JR, Ruan GJ, Abeykoon JP, Ravindran A, Vassallo R, Ryu JH, Tobin WO, Koster MJ, Bennani NN, Rech KL, Shah MV, Witzig TE, Goyal G, Go RS, Mayo Clinic-University of Alabama at Birmingham Histiocytosis Working Group. Classical and non-classical phenotypes of Erdheim-Chester disease: Correlating clinical, radiographic and genotypic findings. Br J Haematol 2022 Nov; 199 (3):454-457 Epub 2022 Aug 26
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  22. Chohan KL, Young JR, Lester S, Alhaj Moustafa M, Rosenthal A, Tun HW, Hoppe BS, Johnston PB, Micallef IN, Habermann TM, Ansell SM. A real-world study of combined modality therapy for early-stage Hodgkin lymphoma: too little treatment impacts outcome. Blood Adv. 2022 Jul 26; 6 (14):4241-4250
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  23. Zanwar S, Abeykoon JP, Dasari S, Ravindran A, Young JR, Acosta-Medina AA, Rech KL, Schwartz J, Mangold A, Rosenthal A, Bennani NN, Shah MV, Morlote D, Goyal G, Go RS. Clinical and therapeutic implications of BRAF fusions in histiocytic disorders. Blood Cancer J 2022 Jun 28; 12 (6):97 Epub 2022 June 28
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  24. Quinn E, Mahowald M, Go RS, Goyal G, Young JR. Multimodality imaging of cardiac involvement in Erdheim-Chester disease. Eur Heart J Cardiovasc Imaging. 2022 Jun 21; 23 (7):e276
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  25. Hu M, Goyal G, Abeykoon JP, Acosta-Medina AA, Ruan GJ, Young JR, Ravindran A, Bennani NN, Shah MV, Vassallo R, Ryu JH, Davidge-Pitts CJ, Koster MJ, Tobin WO, Sartori-Valinotti JC, Rech KL, Go RS. Clinical features and outcomes of non-pulmonary unifocal adult Langerhans cell histiocytosis. Blood Cancer J 2022 Jun 3; 12 (6):89 Epub 2022 June 03
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  26. Desai SH, Pederson L, LaPlant B, Mwangi R, Maurer M, Young JR, Macon WR, King RL, Wang Y, Cerhan JR, Feldman A, Inwards DJ, Micallef I, Johnston P, Porrata LF, Ansell SM, Habermann TM, Witzig TE, Nowakowski GS. PET2 response associated with survival in newly diagnosed diffuse large B-cell lymphoma: results of two independent prospective cohorts. Blood Cancer J. 2022 May 3; 12 (5):78 Epub 2022 May 03
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  27. Goyal G, Tazi A, Go RS, Rech KL, Picarsic JL, Vassallo R, Young JR, Cox CW, Van Laar J, Hermiston ML, Cao XX, Makras P, Kaltsas G, Haroche J, Collin M, McClain KL, Diamond EL, Girschikofsky M. International expert consensus recommendations for the diagnosis and treatment of Langerhans cell histiocytosis in adults. Blood. 2022 Apr 28; 139 (17):2601-2621
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  28. Breen WG, Hathcock MA, Young JR, Kowalchuk RO, Bansal R, Khurana A, Bennani NN, Paludo J, Villasboas Bisneto JC, Wang Y, Ansell SM, Peterson JL, Johnston PB, Lester SC, Lin Y. Metabolic characteristics and prognostic differentiation of aggressive lymphoma using one-month post-CAR-T FDG PET/CT. J Hematol Oncol 2022 Mar 26; 15 (1):36
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  29. Goyal G, Young JR, Abeykoon JP, Shah MV, Bennani NN, Sartori-Valinotti JC, Vassallo R, Ryu JH, Tobin WO, Koster MJ, Davidge-Pitts CJ, Ravindran A, Rech KL, Go RS. Impact of a Multidisciplinary Tumor Board on the Care of Patients with Histiocytic Disorders: The Histiocytosis Working Group experience. Oncologist. 2022 Mar 4; 27 (2):144-148
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  30. Abeykoon JP, Lasho TL, Dasari S, Rech KL, Ranatunga WK, Manske MK, Tischer A, Ravindran A, Young JR, Tobin WO, Flanagan EP, Nowakowski KE, Ruan GJ, Shah MV, Bennani NN, Vassallo R, Ryu JH, Koster MJ, Davidge-Pitts CJ, Patnaik MM, Wu X, Witzig TE, Goyal G, Go RS, Mayo Clinic-University of Alabama at Birmingham Histiocytosis Working Group. Sustained, complete response to pexidartinib in a patient with CSF1R-mutated Erdheim-Chester disease. Am J Hematol. 2022 Mar 1; 97 (3):293-302 Epub 2022 Jan 03
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  31. Abeykoon JP, Ravindran A, Rech KL, Young JR, Oliver Tobin W, Shah MV, Nora Bennani N, Vassallo R, Ryu JH, Koster MJ, Davidge-Pitts CJ, Goyal G, Go RS, Mayo Clinic-University of Alabama at Birmingham Histiocytosis Working Group. Mimics of Erdheim-Chester disease. Br J Haematol. 2022 Feb; 196 (4):984-994 Epub 2021 Nov 20
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  32. Hazim AZ, Ruan GJ, Hu M, Ravindran A, Rech KL, Young JR, Cox CW, Abeykoon JP, Scheckel C, Vassallo R, Ryu JH, Tobin WO, Koster MJ, Bennani NN, Shah MV, Goyal G, Go RS, Mayo Clinic-University of Alabama at Birmingham Histiocytosis Working Group. Langerhans cell histiocytosis with lung involvement in isolation and multisystem disease: Staging, natural history, and comparative survival. Am J Hematol. 2021 Dec 01; 96(12):1604-1610. Epub 2021 Oct 08.
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  33. Navin PJ, Eickstaedt NL, Atwell TD, Young JR, Eiken PW, Welch BT, Schmitz JJ, Schmit GD, Johnson MP, Moynagh MR. Safety and Efficacy of Percutaneous Image-Guided Mediastinal Mass Core-Needle Biopsy. Mayo Clin Proc Innov Qual Outcomes. 2021 Dec; 5(6):1100-1108. Epub 2021 Nov 25.
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  34. Schroeder DG, Jang S, Johnson DR, Takahashi H, Navin PJ, Broski SM, Thorpe MP, Johnson GB, Young JR. Frequency and Characteristics of Nodal and Deltoid FDG and (11)C-Choline Uptake on PET Performed After COVID-19 Vaccination. AJR Am J Roentgenol. 2021 Nov; 217 (5):1206-1216 Epub 2021 May 19
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  35. Harper L, Simmons C, Nathan M, Thanarajasingam G, Kim H, Young J. Establishing Normal Testicular (18)F-FDG PET/CT SUVs. AJR Am J Roentgenol. 2021 Jun; 216 (6):1634-1640 Epub 2021 Apr 14
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  36. Young JR, Graham RP, Venkatesh SK, Kendi AT. (18)F-FDG PET/CT of hepatocellular adenoma subtypes and review of literature. Abdom Radiol (NY). 2021 Jun; 46 (6):2604-2609 Epub 2021 Feb 08
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  37. Goyal G, Abeykoon JP, Hu M, Young JR, Shah MV, Bennani NN, Call TG, Hook CC, Pardanani A, Inwards DJ, Vassallo R, Ryu JH, Tobin WO, Koster MJ, Davidge-Pitts CJ, Ravindran A, Rech KL, Go RS, Mayo Clinic-University of Alabama at Birmingham Histiocytosis Working Group. Single-agent cladribine as an effective front-line therapy for adults with Langerhans cell histiocytosis. Am J Hematol 2021 May 1; 96 (5):E146-E150 Epub 2021 Feb 19
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  38. Higgins A, Kim H, Harper L, Habermann TM, Nowakowski GS, Thompson CA, Johnston P, Witzig TE, Allmer C, Maurer MJ, Cerhan JR, Young JR, Thanarajasingam G. Testicular FDG-PET/CT uptake threshold in aggressive lymphomas. Am J Hematol 2021 Mar 1; 96 (3):E81-E83 Epub 2021 Jan 18
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  39. Burkett BJ, Dundar A, Young JR, Packard AT, Johnson GB, Halfdanarson TR, Eiring RA, Gansen DN, Patton CM, Kendi AT. How We Do It: A Multidisciplinary Approach to (177)Lu DOTATATE Peptide Receptor Radionuclide Therapy. Radiology. 2021 Feb; 298 (2):261-274 Epub 2020 Nov 24
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  40. Habermann TM, Khurana A, Lentz R, Schmitz JJ, von Bormann AG, Young JR, Hunt CH, Christofferson SN, Nowakowski GS, McCullough KB, Horna P, Wood AJ, Macon WR, Kurtin PJ, Lester SC, Stafford SL, Chamarthy U, Khan F, Ansell SM, King RL. Analysis and impact of a multidisciplinary lymphoma virtual tumor board. Leuk Lymphoma. 2020 Dec; 61 (14):3351-3359 Epub 2020 Sept 23
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  41. Hazim AZ, Ruan GJ, Ravindran A, Abeykoon JP, Scheckel C, Vassallo R, Ryu JH, Tobin WO, Koster MJ, Bennani NN, Rech KL, Young JR, Shah MV, Goyal G, Go RS. Efficacy of BRAF-Inhibitor Therapy in BRAF(V600E) -Mutated Adult Langerhans Cell Histiocytosis. Oncologist. 2020 Dec; 25 (12):1001-1004 Epub 2020 Oct 12
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  42. Jaykel TJ, Clark MS, Adamo DA, Welch BT, Thompson SM, Young JR, Ehman EC. Thoracic positron emission tomography: (18)F-fluorodeoxyglucose and beyond. J Thorac Dis. 2020 Nov; 12 (11):6978-6991
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  43. Ruan GJ, Hazim A, Abeykoon JP, Scheckel C, Vassallo R, Ryu JH, Tobin WO, Koster MJ, Bennani NN, Rech KL, Young JR, Shah MV, Goyal G, Go RS. Low-dose vemurafenib monotherapy in BRAF(V600E) -mutated Erdheim-Chester disease. Leuk Lymphoma 2020 Nov; 61 (11):2733-2737 Epub 2020 July 01
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  44. Dundar A, Young JR, Wenger DE, Inwards CY, Broski SM. Unusual manifestations of diffuse-type tenosynovial giant cell tumor in two patients: importance of radiologic-pathologic correlation. Skeletal Radiol. 2020 Mar; 49 (3):483-489 Epub 2019 Oct 28
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  45. Burkett BJ, Arghami A, Bois MC, Breen JF, Young JR. Computed tomographically guided transthoracic biopsy of a cardiac mass in the right ventricular outflow tract. J Thorac Cardiovasc Surg. 2020 Feb; 159 (2):e115-e118 Epub 2019 June 07
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  46. Novo M, Nowakowski GS, Habermann TM, Witzig TE, Micallef IN, Johnston PB, Inwards DJ, Botto B, Ristow KM, Young JR, Vitolo U, Ansell SM. Persistent mediastinal FDG uptake on PET-CT after frontline therapy for Hodgkin lymphoma: biopsy, treat or observe? Leuk Lymphoma. 2020 Feb; 61 (2):318-327 Epub 2019 Sept 26
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  47. Goyal G, Ravindran A, Young JR, Shah MV, Bennani NN, Patnaik MM, Nowakowski GS, Thanarajasingam G, Habermann TM, Vassallo R, Sher T, Parikh SA, Rech KL, Go RS, Mayo Clinic Histiocytosis Working Group. Clinicopathological features, treatment approaches, and outcomes in Rosai-Dorfman disease. Haematologica. 2020; 105 (2):348-357 Epub 2020 Jan 31
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  48. Goyal G, Young JR, Koster MJ, Tobin WO, Vassallo R, Ryu JH, Davidge-Pitts CJ, Hurtado MD, Ravindran A, Sartori Valinotti JC, Bennani NN, Shah MV, Rech KL, Go RS, Mayo Clinic Histiocytosis Working Group. The Mayo Clinic Histiocytosis Working Group Consensus Statement for the Diagnosis and Evaluation of Adult Patients With Histiocytic Neoplasms: Erdheim-Chester Disease, Langerhans Cell Histiocytosis, and Rosai-Dorfman Disease. Mayo Clin Proc. 2019 Oct; 94 (10):2054-2071 Epub 2019 Aug 28
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  49. Young JR, Wallig AE, Fischer NL, Swanson TN, Truty MJ, Shen KR, McMenomy BP. Radiolocalization of atypical lesions for intraoperative identification: technical factors, localization quality, success rates, patient safety, and spectrum of applications. World J Surg Oncol. 2019 May 27; 17 (1):88
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  50. Koslow M, Young JR, Yi ES, Baqir M, Decker PA, Johnson GB, Ryu JH. Rheumatoid pulmonary nodules: clinical and imaging features compared with malignancy. Eur Radiol. 2019 Apr; 29 (4):1684-1692 Epub 2018 Oct 04
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  51. Broski SM, Young JR, Kendi AT, Subramaniam RM. Skeletal Metastasis Evaluation: Value and Impact of PET/Computed Tomography on Diagnosis, Management and Prognosis. PET Clin. 2019 Jan; 14 (1):103-120 Epub 2018 Oct 24
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  52. Byers CDA, Young JR, Connell M. Parapagus dicephalus dibrachius dipus conjoined twin case Applied radiology. 2018; 47(5):29-32.
  53. Young JR, Johnson GB, Murphy RC, Go RS, Broski SM. (18)F-FDG PET/CT in Erdheim-Chester Disease: Imaging Findings and Potential BRAF Mutation Biomarker. J Nucl Med. 2018 May; 59 (5):774-779 Epub 2017 Nov 02
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  54. Penny S, Gridley D, Young J.. Congenital Adrenal Hyperplasia secondary to 3-beta hydroxysteriod dehydrogenase deficieny Applied Radiology The Journal of Pratical Medical Imaging and Managment. November 2017; 46(11).
  55. Nguyen BD, Roarke MC, Young JR, Yang M, Osborn HH. Diuretic Renal Scintigraphy in Patients with Sulfonamide Allergies: Possible Alternative Use of Ethacrynic Acid. J Nucl Med Technol. 2015 Dec; 43: (4)239-41.
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  56. Young J, August D. Massive Esophagus. Southwest Journal of Pulmonary and Critical Care. Medical Image of the Week; 7.
  57. Azar N, Yarmohammadi H, Young J, Nakamoto D. Efficiency of Second Generation Ultrasound Elastography in Characterization of Thyroid Lesions Ultrasound in Medicine and Biology. 2011; 37(8):S8.
PST-20386004