Biographical summary
The research focus of Harry H. Yoon, M.D., is in the development of novel GI malignancies. Dr. Yoon is an internationally recognized expert and clinical investigator in gastroesophageal and other GI cancers. Through his leadership roles, Dr. Yoon helps provide strategic leadership for scientific, practice, and educational activities within the Mayo Clinic Comprehensive Cancer Center, the Department of Oncology in Rochester, MN, and across the three national Mayo Clinic destination sites (Minnesota, Arizona, Florida) and Mayo Clinic Health System. The theme of Dr. Yoon's research career has been to develop genomic/molecularly-informed therapies in GI cancers tailored to an individual's tumor and host environment. He leads an R01-funded clinical/translational research program from the U.S. National Institutes of Health/National Cancer Institute that seeks to enhance cooperativity of immunotherapy with anti-angiogenic and other therapies. He (co)leads multiple investigator-initiated and Industry-sponsored Phase 1-3 clinical trials. He is frequently invited to speak at internationally attended scientific conferences, including those sponsored by the American Society of Clinical Oncology (ASCO) and European Society of Medical Oncology (ESMO) and to serve on global advisory boards of pharmaceutical/biotechnology firms to guide innovation in drug development. He serves on the guidelines panel of the U.S. National Comprehensive Cancer Network (NCCN) for esophageal/gastroesophageal junction and gastric cancer. He has expertise in cancers of the digestive system.
Interests
- Gastrointestinal cancers
- Esophageal/gastroesophageal junction or gastric cancers
- Colon cancer
- Rectal cancer
- Pancreaticobiliary cancer
- Small bowel cancer
Mayo Clinic locations
Education
- 2008
Clinical Post Doctoral Fellowship - Medical OncologyThe Johns Hopkins University School of Medicine
- 2006
MHSGraduate Training Program in Clinical Investigation (GTPCI), Johns Hopkins School of Public Health
- 2004
Internship/Residency - Internal MedicineTraditional Program, Yale-New Haven Hospital, Yale University School of Medicine
- 2001
MDYale University School of Medicine
- 1993
BS - Molecular Biophysics & BiochemistryYale College
Activities and honors
Certifications
- 2007
Medical OncologyAmerican Board of Internal Medicine
Awards and honors
- 2011
Charles F. and Marcia L. Forcey Career Development Award in Esophageal Cancer ResearchMayo Clinic Development Department and Cancer Center
- 2010
Top Educator 2010Internal Medicine Residency Program, Department of Internal Medicine
- 2008
Diagnostic Development Tutorial: From Hypothesis to ProductAACR-NCI-EORTC Conference on Molecular Targets and Cancer Therapeutics, American Association for Cancer Research
- 2008
Paul Calabresi (K12) Clinical Translational Research Career Development ProgramMayo Clinic Cancer Center
- 2007
Young Investigator AwardAmerican Society of Clinical Oncology
- 2001
ACP/ASIM Internal Medicine AwardConnecticut Chapter ACP-ASIM
- 1989
Cum LaudeYale College
Professional memberships
- 2022 - present
Member and ReviewerKL2 Scientific Review Committee
- 2022
Session leaderMayo Clinic GI Disease Groups
- 2022
National Advisory BoardDaiichi Sankyo and AstraZeneca
- 2022 - present
GI Executive Advisory CouncilAmgen Pharmaceuticals
- 2022 - present
Global Steering Committee MemberBeiGene
- 2021
Esophageal Cancer Advisory BoardBeiGene
- 2021
Esophageal Cancer Advisory BoardNovartis Pharmaceuticals
- 2021
Global Gastric Cancer Advisory BoardBristol Myers Squibb
- 2021
National Mock FDA Advisory BoardMerck & Co., Inc.
- 2021
Gastric Cancer Advisory BoardZymeworks
- 2021
National Gastric Cancer Advisory BoardOncXerna
- 2020
Global Gastric Cancer Advisory BoardZymeworks
- 2020
Global Gastric Cancer Advisory BoardMacrogenics
- 2019 - present
Active MemberGI Disease Group Steering Committee
- 2019
MemberAstellas Pharma Inc
- 2019
MemberALX Oncology
- 2019
MemberFivePrime
- 2019
Advisory Board MemberMerck Research Laboratories
- 2019 - present
Steering Committee MemberMacrogenics
- 2019 - present
MemberEsophageal and Gastric Cancer Committee, National Comprehensive Cancer Network
- 2018 - present
Co-ChairBeiGene
- 2018 - present
Steering Committee MemberMerck Research Laboratories
- 2018 - present
Steering Committee MemberLSK Biopharma
- 2017 - present
ChairGastroesophageal Cancer Disease Group, Mayo Clinic Cancer Center
- 2017 - present
MemberGI Lab Med & Pathol Disease-Oriented Group
- 2016 - 2019
Alliance GI RepresentativeMayo Clinic Cancer Center, Alliance for Clinical Trials in Oncology, Esophagogastric Task Force of the Gastrointestinal Steering Committee
- 2015 - 2020
PanelistNational Comprehensive Cancer Network Occult Primary Guidelines Panel
- 2015 - present
Faculty AdvisorThe Angiogenesis Foundation Center of Excellence
- 2014
Advisory Board MemberLilly Oncology
- 2014 - 2017
MemberGastric-Esophageal Cancer Specialty Council
- 2014
AdvisorFivePrime Gastric Cancer Advisory Board
- 2013 - present
MemberMerrimack MM-111 Translational Science Steering Committee
- 2012 - 2014
MemberAcademic and Community Cancer Research United, Mayo Clinic Cancer Center
- 2012
MemberTask Force - Standardizing clinical management of patients with esophageal cancer
- 2011
Advisory Board MemberGenentech USA
- 2011 - present
MemberAcademic and Community Clinical Research United
- 2010 - 2014
MemberNCI Task Force, National Cancer Institute, National Institutes of Health
- 2010
Advisory Board MemberGenentech USA
- 2009 - present
Ad Hoc ReviewerMayo Clinic Scientific Review Committee
- 2008 - present
MemberAmerican Association for Cancer Research
- 2008 - 2014
MemberGI Cancers DOG, Disease/Discipline Oriented Groups (DOGs), Mayo Clinic Cancer Center
- 2008 - 2012
MemberNorth Central Cancer Treatment Group, NCI Cooperative Group Affiliation, National Cancer Institute
- 2008 - present
MemberEsophageal Adenocarcinoma Barretts Esophagus Consortium
- 2008 - present
MemberMinnesota Medical Association
- 2006 - present
MemberAmerican Society of Clinical Oncology
Publications
Research activities