Publications Print Wilson BE, Wright BL, Swing T, Schroeder S, Bauer CS. Eosinophilic esophagitis in Native American children and young adults: A case control study. Ann Allergy Asthma Immunol. 2024 Oct; 133 (4):476-480 Epub 2024 July 26 View PubMed Wright BL, Abonia JP, Abud EM, Aceves SS, Ackerman SJ, Braskett M, Chang JW, Chehade M, Constantine GM, Davis CM, Dellon ES, Doyle AD, Durban R, Hill DA, Jensen ET, Kewalramani A, Khoury P, Klion AD, Kottyan L, Kuang FL, McGowan EC, Ruffner MA, Spencer LA, Spergel JM, Uchida AM, Wechsler JB, Pesek RD. Advances and ongoing challenges in eosinophilic gastrointestinal disorders presented at the CEGIR/TIGERs Symposium at the 2024 American Academy of Allergy, Asthma & Immunology meeting. J Allergy Clin Immunol. 2024 Oct; 154 (4):882-892 Epub 2024 Aug 05 View PubMed Pyon GC, Masuda MY, Putikova A, Luo H, Gibson JB, Dao AD, Ortiz DR, Heiligenstein PL, Bonellos JJ, LeSuer WE, Pai RK, Garg S, Rank MA, Nakagawa H, Kita H, Wright BL, Doyle AD. Tissue-specific inducible IL-33 expression elicits features of eosinophilic esophagitis. J Allergy Clin Immunol. 2024 Sep 10 Epub 2024 Sept 10 View PubMed Chehade M, Wright BL, Walsh S, Bailey DD, Muir AB, Klion AD, Collins MH, Davis CM, Furuta GT, Gupta S, Khoury P, Peterson KA, Jensen ET. Challenging assumptions about the demographics of eosinophilic gastrointestinal diseases: A systematic review. J Allergy Clin Immunol Glob. 2024 Aug; 3 (3):100260 Epub 2024 Apr 16 View PubMed Wilson BE, Sacta MA, Wright BL, Spergel J, Wolfset N. The Relationship Between Eosinophilic Esophagitis and Immunotherapy. Immunol Allergy Clin North Am. 2024 May; 44 (2):281-291 Epub 2024 Feb 14 View PubMed Masuda MY, Pyon GC, Luo H, LeSuer WE, Putikova A, Dao A, Ortiz DR, Schulze AR, Fritz N, Kobayashi T, Iijima K, Klein-Szanto AJ, Shimonosono M, Flashner S, Morimoto M, Pai RK, Rank MA, Nakagawa H, Kita H, Wright BL, Doyle AD. Epithelial overexpression of IL-33 induces eosinophilic esophagitis dependent on IL-13. J Allergy Clin Immunol. 2024 May; 153 (5):1355-1368 Epub 2024 Feb 03 View PubMed Chehade M, McGowan EC, Wright BL, Muir AB, Klion AD, Furuta GT, Jensen ET, Bailey DD. Barriers to Timely Diagnosis of Eosinophilic Gastrointestinal Diseases. J Allergy Clin Immunol Pract. 2024 Feb; 12 (2):302-308 Epub 2023 Dec 17 View PubMed Hirano I, Dellon ES, Falk GW, Gonsalves NP, Furuta GT, Bredenoord AJ, ASCENT WORKING GROUP, Talley NJ, Katzka D, Wright BL. Ascending to New Heights for Novel Therapeutics for Eosinophilic Esophagitis. Gastroenterology. 2024 Jan; 166 (1):1-10 Epub 2023 Sept 09 View PubMed Gruden E, Kienzl M, Ristic D, Kindler O, Kaspret DM, Schmid ST, Kargl J, Sturm E, Doyle AD, Wright BL, Baumann-Durchschein F, Konrad J, Blesl A, Schlager H, Schicho R. Mononuclear cell composition and activation in blood and mucosal tissue of eosinophilic esophagitis. Front Immunol. 2024; 15:1347259 Epub 2024 Jan 22 View PubMed Wilson BE, Meltzer EC, Wright BL. Ethical Implications of Continuing Oral Immunotherapy After the Development of Eosinophilic Esophagitis. J Allergy Clin Immunol Pract. 2023 Dec; 11 (12):3638-3644 Epub 2023 Aug 10 View PubMed Chehade M, Wright BL, Atkins D, Aceves SS, Ackerman SJ, Assa'ad AH, Bauer M, Collins MH, Commins SP, Davis CM, Dellon ES, Doerfler B, Gleich GJ, Gupta SK, Hill DA, Jensen ET, Katzka D, Kliewer K, Kodroff E, Kottyan LC, Kyle S, Muir AB, Pesek RD, Peterson K, Shreffler WG, Spergel JM, Strobel MJ, Wechsler J, Zimmermann N, Furuta GT, Rothenberg ME. Breakthroughs in understanding and treating eosinophilic gastrointestinal diseases presented at the CEGIR/TIGERs Symposium at the 2022 American Academy of Allergy, Asthma & Immunology Meeting. J Allergy Clin Immunol. 2023 Dec; 152 (6):1382-1393 Epub 2023 Sept 03 View PubMed Marella S, Sharma A, Ganesan V, Ferrer-Torres D, Krempski JW, Idelman G, Clark S, Nasiri Z, Vanoni S, Zeng C, Dlugosz AA, Zhou H, Wang S, Doyle AD, Wright BL, Spence JR, Chehade M, Hogan SP. IL-13-induced STAT3-dependent signaling networks regulate esophageal epithelial proliferation in eosinophilic esophagitis. J Allergy Clin Immunol. 2023 Dec; 152 (6):1550-1568 Epub 2023 Aug 29 View PubMed Ochoa S, Abers MS, Rosen LB, Rump A, Howe K, Lieberman JA, Wright BL, Suez D, Krausz M, Grimbacher B, Lionakis MS, Uzel G. Management and outcome of COVID-19 in CTLA-4 insufficiency. Blood Adv. 2023 Oct 10; 7 (19):5743-5751 View PubMed Wright BL, Masuda MY, Ortiz DR, Dao A, Civello B, Pyon GC, Schulze AR, Yiannas JA, Rank MA, Kita H, Doyle AD. Allergies Come Clean: The Role of Detergents in Epithelial Barrier Dysfunction. Curr Allergy Asthma Rep. 2023 Aug; 23 (8):443-451 Epub 2023 May 26 View PubMed LeSuer WE, Kienzl M, Ochkur SI, Schicho R, Doyle AD, Wright BL, Rank MA, Krupnick AS, Kita H, Jacobsen EA. Eosinophils promote effector functions of lung group 2 innate lymphoid cells in allergic airway inflammation in mice. J Allergy Clin Immunol. 2023 Aug; 152 (2):469-485.e10 Epub 2023 Apr 06 View PubMed Masuda MY, LeSuer WE, Horsley-Silva JL, Putikova A, Buras MR, Gibson JB, Pyon GC, Simmons TD, Doyle AD, Wright BL. Food-Specific IgG4 Is Elevated Throughout the Upper Gastrointestinal Tract in Eosinophilic Esophagitis. Dig Dis Sci. 2023 Jun; 68 (6):2406-2413 Epub 2023 Mar 27 View PubMed Sindher SB, Barshow S, Tirumalasetty J, Arasi S, Atkins D, Bauer M, Begin P, Collins MH, Deschildre A, Doyle AD, Fiocchi A, Furuta GT, Garcia-Lloret M, Mennini M, Rothenberg ME, Spergel JM, Wang J, Wood RA, Wright BL, Zuberbier T, Chin AR, Long A, Nadeau KC, Chinthrajah RS. The role of biologics in pediatric food allergy and eosinophilic gastrointestinal disorders. J Allergy Clin Immunol. 2023 Mar; 151 (3):595-606 View PubMed Doyle AD, Masuda MY, Pyon GC, Luo H, Putikova A, LeSuer WE, Flashner S, Rank MA, Nakagawa H, Kita H, Wright BL. Detergent exposure induces epithelial barrier dysfunction and eosinophilic inflammation in the esophagus. Allergy. 2023 Jan; 78 (1):192-201 Epub 2022 Aug 08 View PubMed Chehade M, Furuta G, Klion A, Abonia JP, Aceves S, Bose P, Collins MH, Davis C, Dellon ES, Eickel G, Falk G, Gupta S, Hiremath G, Howard A, Jensen ET, Kesh S, Khoury P, Kocher K, Kodroff E, Kyle S, Mak N, McCoy D, Mehta P, Menard-Katcher P, Mukkada V, Paliana A, Rothenberg M, Sable K, Schmitt C, Scott M, Spergel J, Strobel MJ, Wechsler JB, Yang GY, Zicarelli A, Muir AB, Wright BL, Bailey DD. Enhancing diversity, equity, inclusion, and accessibility in eosinophilic gastrointestinal disease research: the consortium for eosinophilic gastrointestinal disease researchers' journey. Ther Adv Rare Dis. 2023 Jan-Dec; 4:26330040231180895 Epub 2023 Aug 14 View PubMed Dellon ES, Gonsalves N, Abonia JP, Alexander JA, Arva NC, Atkins D, Attwood SE, Auth MKH, Bailey DD, Biederman L, Blanchard C, Bonis PA, Bose P, Bredenoord AJ, Chang JW, Chehade M, Collins MH, Di Lorenzo C, Dias JA, Dohil R, Dupont C, Falk GW, Ferreira CT, Fox AT, Genta RM, Greuter T, Gupta SK, Hirano I, Hiremath GS, Horsley-Silva JL, Ishihara S, Ishimura N, Jensen ET, Gutierrez-Junquera C, Katzka DA, Khoury P, Kinoshita Y, Kliewer KL, Koletzko S, Leung J, Liacouras CA, Lucendo AJ, Martin LJ, McGowan EC, Menard-Katcher C, Metz DC, Miller TL, Moawad FJ, Muir AB, Mukkada VA, Murch S, Nhu QM, Nomura I, Nurko S, Ohtsuka Y, Oliva S, Orel R, Papadopoulou A, Patel DA, Pesek RD, Peterson KA, Philpott H, Putnam PE, Richter JE, Rosen R, Ruffner MA, Safroneeva E, Schreiner P, Schoepfer A, Schroeder SR, Shah N, Souza RF, Spechler SJ, Spergel JM, Straumann A, Talley NJ, Thapar N, Vandenplas Y, Venkatesh RD, Vieira MC, von Arnim U, Walker MM, Wechsler JB, Wershil BK, Wright BL, Yamada Y, Yang GY, Zevit N, Rothenberg ME, Furuta GT, Aceves SS. International Consensus Recommendations for Eosinophilic Gastrointestinal Disease Nomenclature. Clin Gastroenterol Hepatol. 2022 Nov; 20 (11):2474-2484.e3 Epub 2022 Feb 16 View PubMed Masuda MY, Barshow SM, Garg S, Putikova A, LeSuer WE, Alexander JA, Katzka DA, Dellon ES, Kita H, Horsley-Silva JL, Doyle AD, Wright BL. Eosinophil Peroxidase Staining Enhances the Diagnostic Utility of the Cytosponge in Eosinophilic Esophagitis. Clin Transl Gastroenterol. 2022 Nov 1; 13 (11):e00534 Epub 2022 Nov 01 View PubMed Freeman CM, Barry TD, Bauer CS, Miller HK, Rukasin CR, Wright BL. GATA2 deficiency associated with copy number variation: A reference for considering inborn errors of immunity. J Allergy Clin Immunol Pract. 2022 Sep; 10 (9):2476-2478.e9 Epub 2022 May 30 View PubMed Booth NA, Freeman CM, Wright BL, Rukasin C, Badia P, Daines M, Bauer CS, Miller H. Severe Combined Immunodeficiency (SCID) Screening in Arizona: Lessons Learned from the First 2 Years. J Clin Immunol. 2022 Aug; 42 (6):1321-1329 Epub 2022 June 22 View PubMed Cortes LM, Brodsky D, Chen C, Pridgen T, Odle J, Snider DB, Cruse G, Putikova A, Masuda MY, Doyle AD, Wright BL, Dawson HD, Blikslager A, Dellon ES, Laster SM, Kaser T. Immunologic and pathologic characterization of a novel swine biomedical research model for eosinophilic esophagitis. Front Allergy. 2022; 3:1029184 Epub 2022 Nov 14 View PubMed Freeman C, Hines B, Hines J, Hoxworth J, Wright B. Lingual Tonsillectomy: Successful Treatment of Periodic Fever, Aphthous Stomatitis, Pharyngitis, and Cervical Adenitis Syndrome. J Clin Rheumatol. 2021 Dec 1; 27 (8S):S627 View PubMed Adeleye O, Trickett JS, Wright BL, Khan A. Refractory eosinophilic cystitis controlled with low-dose cyclosporine therapy: A case report. Urol Case Rep. 2021 Nov; 39:101829 Epub 2021 Sept 02 View PubMed Hasan SH, Taylor S, Garg S, Buras MR, Doyle AD, Bauer CS, Wright BL, Schroeder S. Diagnosis of Pediatric Non-Esophageal Eosinophilic Gastrointestinal Disorders by Eosinophil Peroxidase Immunohistochemistry. Pediatr Dev Pathol. 2021 Nov-Dec; 24 (6):513-522 Epub 2021 June 28 View PubMed Wright BL, Fernandez-Becker NQ, Kambham N, Purington N, Cao S, Tupa D, Zhang W, Sindher SB, Rank MA, Kita H, Katzka DA, Shim KP, Bunning BJ, Doyle AD, Jacobsen EA, Tsai M, Boyd SD, Manohar M, Chinthrajah RS. Gastrointestinal Eosinophil Responses in a Longitudinal, Randomized Trial of Peanut Oral Immunotherapy. Clin Gastroenterol Hepatol. 2021 Jun; 19 (6):1151-1159.e14 Epub 2020 May 17 View PubMed Freeman CM, Murillo JC, Hines BT, Wright BL, Schroeder SR, Bauer CS. Learning early about peanut-triggered food protein-induced enterocolitis syndrome. J Food Allergy. 2021 Apr; 3 (1):32-36 Epub 2021 Apr 01 View PubMed Wright BL, Doyle AD, Shim KP, Pai RK, Barshow SM, Horsley-Silva JL, Luo H, Rank MA, Jacobsen EA, Katzka DA, Kita H, Dellon ES. Image Analysis of Eosinophil Peroxidase Immunohistochemistry for Diagnosis of Eosinophilic Esophagitis. Dig Dis Sci. 2021 Mar; 66 (3):775-783 Epub 2020 Apr 04 View PubMed Hamant L, Freeman C, Garg S, Wright BL, Schroeder S. Eosinophilic esophagitis may persist after discontinuation of oral immunotherapy. Ann Allergy Asthma Immunol 2021 Mar; 126 (3):299-302 Epub 2020 Dec 17 View PubMed Schreiner P, Biedermann L, Greuter T, Wright BL, Straumann A. How to approach adult patients with asymptomatic esophageal eosinophilia. Dis Esophagus. 2021 Jan 11; 34 (1) View PubMed Lin B, Torreggiani S, Kahle D, Rumsey DG, Wright BL, Montes-Cano MA, Silveira LF, Alehashemi S, Mitchell J, Aue AG, Ji Z, Jin T, de Jesus AA, Goldbach-Mansky R. Case Report: Novel SAVI-Causing Variants in STING1 Expand the Clinical Disease Spectrum and Suggest a Refined Model of STING Activation. Front Immunol. 2021; 12:636225 Epub 2021 Mar 22 View PubMed Doyle AD, Masuda MY, Kita H, Wright BL. Eosinophils in Eosinophilic Esophagitis: The Road to Fibrostenosis is Paved With Good Intentions. Front Immunol. 2020; 11:603295 Epub 2020 Dec 01 View PubMed Dellon ES, Guo R, McGee SJ, Hamilton DK, Nicolai E, Covington J, Moist SE, Arrington A, Wright BL, Burks AW, Vickery BP, Kulis M. A Novel Allergen-Specific Immune Signature-Directed Approach to Dietary Elimination in Eosinophilic Esophagitis. Clin Transl Gastroenterol. 2019 Dec; 10 (12):e00099 View PubMed Lal D, Wright BL, Shim KP, Zarka MA, Lee JJ, Chang YH, Ochkur SI, Divekar R, Doyle AD, Jacobsen EA, Kita H, Rank MA. Eosinophil peroxidase, GATA3, and T-bet as tissue biomarkers in chronic rhinosinusitis. J Allergy Clin Immunol 2019 Jun; 143 (6):2284-2287.e6 Epub 2019 Feb 08 View PubMed Doyle AD, Mukherjee M, LeSuer WE, Bittner TB, Pasha SM, Frere JJ, Neely JL, Kloeber JA, Shim KP, Ochkur SI, Ho T, Svenningsen S, Wright BL, Rank MA, Lee JJ, Nair P, Jacobsen EA. Eosinophil-derived IL-13 promotes emphysema. Eur Respir J. 2019 May; 53(5). Epub 2019 May 30. View PubMed Kurten RC, Rawson R, Shoda T, Duong LD, Adejumobi D, Levy R, Newbury RO, Rothenberg ME, Akuthota P, Wright BL, Dohil R, Jones SM, Aceves SS. Development and Application of a Functional Human Esophageal Mucosa Explant Platform to Eosinophilic Esophagitis. Sci Rep. 2019 Apr 17; 9 (1):6206 View PubMed Nguyen N, Baumgarten A, Wright BL, Capocelli KE, Pan Z, Lee JJ, Furuta GT, Masterson JC. Histologic similarities in children with eosinophilic esophagitis and proton pump inhibitor-responsive esophageal eosinophilia. J Allergy Clin Immunol 2019 Mar; 143 (3):1237-1240.e2 Epub 2018 Nov 14 View PubMed Wright BL, Spergel JM. Eosinophilic Esophagitis. J Allergy Clin Immunol Pract. 2018 Sep - Oct; 6 (5):1799-1801 View PubMed Hines BT, Rank MA, Wright BL, Marks LA, Hagan JB, Straumann A, Greenhawt M, Dellon ES. Minimally invasive biomarker studies in eosinophilic esophagitis: A systematic review. Ann Allergy Asthma Immunol. 2018 Aug; 121 (2):218-228 Epub 2018 May 16 View PubMed Bennett N, Maglione PJ, Wright BL, Zerbe C. Infectious Complications in Patients With Chronic Granulomatous Disease. J Pediatric Infect Dis Soc. 2018 May 9; 7 (suppl_1):S12-S17 View PubMed Wright BL, Nguyen N, Shim KP, Masterson JC, Jacobsen EA, Ochkur SI, Lee JJ, Furuta GT. Increased GATA-3 and T-bet expression in eosinophilic esophagitis versus gastroesophageal reflux disease. J Allergy Clin Immunol 2018 May; 141 (5):1919-1921.e5 Epub 2018 Jan 31 View PubMed Wright BL, Ochkur SI, Olson NS, Shim KP, Jacobsen EA, Rank MA, Dellon ES, Lee JJ. Normalized serum eosinophil peroxidase levels are inversely correlated with esophageal eosinophilia in eosinophilic esophagitis. Dis Esophagus. 2018 Feb 1; 31 (2) View PubMed Dunn K, Pasternak B, Kelsen JR, Sullivan KE, Dawany N, Wright BL. Mevalonate kinase deficiency presenting as recurrent rectal abscesses and perianal fistulae. Ann Allergy Asthma Immunol. 2018 Feb; 120 (2):214-215 Epub 2017 Dec 28 View PubMed Wright BL, Fernandez-Becker NQ, Kambham N, Purington N, Tupa D, Zhang W, Rank MA, Kita H, Shim KP, Bunning BJ, Doyle AD, Jacobsen EA, Boyd SD, Tsai M, Maecker H, Manohar M, Galli SJ, Nadeau KC, Chinthrajah RS. Baseline Gastrointestinal Eosinophilia Is Common in Oral Immunotherapy Subjects With IgE-Mediated Peanut Allergy. Front Immunol. 2018; 9:2624 Epub 2018 Nov 22 View PubMed Schroeder S, Ochkur SI, Shim KP, Galvin KM, Bauer CS, Lee JJ, Wright BL. Throat-derived eosinophil peroxidase is not a reliable biomarker of pediatric eosinophilic esophagitis. J Allergy Clin Immunol Pract 2017 Nov - Dec; 5 (6):1804-1805 View PubMed Vickery BP, Berglund JP, Burk CM, Fine JP, Kim EH, Kim JI, Keet CA, Kulis M, Orgel KG, Guo R, Steele PH, Virkud YV, Ye P, Wright BL, Wood RA, Burks AW. Early oral immunotherapy in peanut-allergic preschool children is safe and highly effective. J Allergy Clin Immunol. 2017 Jan; 139 (1):173-181.e8 Epub 2016 Aug 10 View PubMed Wright BL, Kulis M, Guo R, Orgel KA, Wolf WA, Burks AW, Vickery BP, Dellon ES. Food-specific IgG4 is associated with eosinophilic esophagitis. J Allergy Clin Immunol 2016 Oct; 138 (4):1190-1192.e3 Epub 2016 Apr 06 View PubMed Orgel KA, Duan S, Wright BL, Maleki SJ, Wolf JC, Vickery BP, Burks AW, Paulson JC, Kulis MD, Macauley MS. Exploiting CD22 on antigen-specific B cells to prevent allergy to the major peanut allergen Ara h 2. J Allergy Clin Immunol. 2016 Aug 20; View PubMed Wright BL, Kulis M, Orgel KA, Burks AW, Dawson P, Henning AK, Jones SM, Wood RA, Sicherer SH, Lindblad RW, Stablein D, Leung DY, Vickery BP, Sampson HA, Consortium of Food Allergy Research. Component-resolved analysis of IgA, IgE, and IgG4 during egg OIT identifies markers associated with sustained unresponsiveness. Allergy. 2016 Mar 25; View PubMed Wright BL, Butterfield JH, Leiferman KM, Gleich GJ. Development of eosinophilic endomyocardial disease in a patient with episodic angioedema and eosinophilia. J Allergy Clin Immunol Pract. 2016 Mar-Apr; 4 (2):336-7 Epub 2015 Nov 07 View PubMed Wright BL, Walkner M, Vickery BP, Gupta RS. Clinical Management of Food Allergy. Pediatr Clin North Am. 2015 Dec; 62: (6)1409-24. View PubMed Lanser BJ, Wright BL, Orgel KA, Vickery BP, Fleischer DM. Current Options for the Treatment of Food Allergy. Pediatr Clin North Am. 2015 Dec; 62 (6):1531-49 Epub 2015 Sept 07 View PubMed Wright BL. Anaphylaxis and epinephrine in North Carolina public schools. Ann Allergy Asthma Immunol 2015 Jul; 115 (1):75-7 Epub 2015 May 08 View PubMed Kulis M, Wright BL, Jones SM, Burks AW. Diagnosis, management, and investigational therapies for food allergies. Gastroenterology. 2015 May; 148(6):1132-42. Epub 2015 Jan 26. View PubMed Smith LL, Wright BL, Buckley RH. Successful treatment of disseminated BCG in a patient with severe combined immunodeficiency. J Allergy Clin Immunol Pract 2015 May-Jun; 3 (3):438-40 Epub 2015 Jan 22 View PubMed Wright BL, Leiferman KM, Gleich GJ. Eosinophil granule protein localization in eosinophilic endomyocardial disease. N Engl J Med 2011 Jul 14; 365 (2):187-8 View PubMed PST-20408298 Home Publications