Publications Print Figueroa-Parra G, Meade-Aguilar JA, Hulshizer CA, Gunderson TM, Chamberlain AM, Thanarajasingam U, Greenlund KJ, Barbour KE, Crowson CS, Duarte-Garcia A. Multimorbidity in systemic lupus erythematosus in a population-based cohort: the Lupus Midwest Network. Rheumatology (Oxford). 2024 Nov 1; 63 (11):3056-3064 View PubMed Sanchez-Rodriguez A, Meade-Aguilar JA, Yang JX, Figueroa-Parra G, Hanson AC, Langenfeld HE, Thanarajasingam U, Chamberlain AM, Greenlund KJ, Barbour KE, Crowson CS, Duarte-Garcia A. Clinical Presentation, Care Pathways, and Delays in Access to Specialized Care in Patients With Systemic Lupus Erythematosus: A Study From Lupus Midwest Network (LUMEN). Arthritis Care Res (Hoboken). 2024 Oct 14 [Epub ahead of print] View PubMed Nln I, Shum J, Ghodke-Puranik Y, Tipon R, Triese D, Amin S, Makol A, Osborn T, Chowdhary V, Thanarajasingam U, Wampler Muskardin TL, Muskardin TLW, Oke V, Gunnarsson I, Zickert A, Zervou MI, Boumpas DT, Svenungsson E, Goulielmos GN, Niewold TB. Regional European genetic ancestry predicts type I interferon level and risk of severe viral infection. QJM. 2024 Aug 1; 117 (8):581-588 View PubMed Fa'ak F, Buni M, Falohun A, Lu H, Song J, Johnson DH, Zobniw CM, Trinh VA, Awiwi MO, Tahon NH, Elsayes KM, Ludford K, Montazari EJ, Chernis J, Dimitrova M, Sandigursky S, Sparks JA, Abu-Shawer O, Rahma O, Thanarajasingam U, Zeman AM, Talukder R, Singh N, Chung SH, Grivas P, Daher M, Abudayyeh A, Osman I, Weber J, Tayar JH, Suarez-Almazor ME, Abdel-Wahab N, Diab A. Selective immune suppression using interleukin-6 receptor inhibitors for management of immune-related adverse events. J Immunother Cancer. 2023 Jun; 11 (6) View PubMed Munroe ME, Blankenship D, DeFreese D, Purushothaman M, DeJager W, Macwana S, Guthridge JM, Kamp S, Redinger N, Aberle T, Chakravarty EF, Arriens C, Li Y, Zeng H, McCarthy-Fruin KA, Osei-Onomahm SA, Thanarajasingam U, James JA, Jupe E. A Flare Risk Index Informed by Select Immune Mediators in Systemic Lupus Erythematosus. Arthritis Rheumatol. 2023 May; 75 (5):723-735 Epub 2023 Mar 06 View PubMed An Z, Figueroa-Parra G, Zhou X, Li Y, Jaquith J, McCarthy-Fruin K, Sletten J, Warrington KJ, Weyand C, Crowson CS, Chumsri S, Knutson KL, Sanchez-Rodriguez A, Thanarajasingam U, Duarte-Garcia A, Zeng H. Immune responses and disease biomarker long-term changes following COVID-19 mRNA vaccination in a cohort of rheumatic disease patients. Front Immunol. 2023; 14:1224702 Epub 2023 July 31 View PubMed Privalle AN, MacLaughlin KL, Thanarajasingam U, Wetter DA. Extensive scarring alopecia and widespread rash. J Fam Pract. 2022 Mar; 71 (2):E13-E15 View PubMed Castillo RM, Sandefur BJ, Finch AS, Richter MD, Thanarajasingam U. Clinical Presentations and Outcomes of Patients Receiving Immune Checkpoint Inhibitors Presenting to the Emergency Department. Mayo Clin Proc Innov Qual Outcomes. 2021 Dec; 5 (6):1029-1035 Epub 2021 Oct 30 View PubMed Paknikar SS, Crowson CS, Davis JM, Thanarajasingam U. Exploring the Role of Antinuclear Antibody Positivity in the Diagnosis, Treatment, and Health Outcomes of Patients With Rheumatoid Arthritis. ACR Open Rheumatol. 2021 Jun; 3 (6):422-426 Epub 2021 May 31 View PubMed Liu Y, Jaquith JM, Mccarthy-Fruin K, Zhu X, Zhou X, Li Y, Crowson C, Davis JM 3rd, Thanarajasingam U, Zeng H. Immune checkpoint inhibitor-induced inflammatory arthritis: a novel clinical entity with striking similarities to seronegative rheumatoid arthritis. Clin Rheumatol. 2020 Dec; 39 (12):3631-3637 Epub 2020 May 30 View PubMed Thanarajasingam U, Abdel-Wahab N. Immune Checkpoint Inhibition-Does It Cause Rheumatic Diseases? Mechanisms of Cancer-Associated Loss of Tolerance and Pathogenesis of Autoimmunity. Rheum Dis Clin North Am. 2020 Aug; 46 (3):587-603 Epub 2020 June 07 View PubMed Bilodeau PA, Kumar V, Rodriguez AE, Li CT, Sanchez-Alvarez C, Thanarajasingam U, Zalewski NL, Flanagan EP. MOG-IgG myelitis coexisting with systemic lupus erythematosus in the post-partum setting. Mult Scler. 2020 Jul; 26 (8):997-1000 Epub 2019 Oct 17 View PubMed Thanarajasingam U, Muppirala AN, Jensen MA, Ghodke-Puranik Y, Dorschner JM, Vsetecka DM, Amin S, Makol A, Ernste F, Osborn T, Moder K, Chowdhary V, Niewold TB. Type I Interferon Predicts an Alternate Immune System Phenotype in Systemic Lupus Erythematosus. ACR Open Rheumatol. 2019 Oct; 1 (8):499-506 Epub 2019 Aug 19 View PubMed Richter MD, Crowson C, Kottschade LA, Finnes HD, Markovic SN, Thanarajasingam U. Rheumatic Syndromes Associated With Immune Checkpoint Inhibitors: A Single-Center Cohort of Sixty-One Patients. Arthritis Rheumatol. 2019 Mar; 71 (3):468-475 Epub 2019 Jan 28 View PubMed Richter MD, Pinkston O, Kottschade LA, Finnes HD, Markovic SN, Thanarajasingam U. Brief Report: Cancer Immunotherapy in Patients With Preexisting Rheumatic Disease: The Mayo Clinic Experience. Arthritis Rheumatol. 2018 Mar; 70 (3):356-360 Epub 2018 Feb 06 View PubMed Thanarajasingam U, Jensen MA, Dorschner JM, Wampler Muskardin T, Ghodke-Puranik Y, Purmalek M, Eliopoulos E, Zervou MI, Goulielmos GN, Howard M, Kaplan MJ, Niewold TB. Brief Report: A Novel ELANE Mutation Associated With Inflammatory Arthritis, Defective NETosis, and Recurrent Parvovirus Infection. Arthritis Rheumatol. 2017 Dec; 69 (12):2396-2401 Epub 2017 Nov 08 View PubMed Childs DS, Tracy SI, Thanarajasingam U. 46-Year-Old Man With Lower Back Pain. Mayo Clin Proc. 2017 Oct; 92 (10):e133-e137 Epub 2017 Aug 24 View PubMed Barbosa NS, Wetter DA, Wieland CN, Shenoy NK, Markovic SN, Thanarajasingam U. Scleroderma Induced by Pembrolizumab: A Case Series. Mayo Clin Proc. 2017 Jul; 92 (7):1158-1163 Epub 2017 June 07 View PubMed Shenoy N, Esplin B, Barbosa N, Wieland C, Thanarajasingam U, Markovic S. Pembrolizumab induced severe sclerodermoid reaction. Ann Oncol 2017 Feb 1; 28 (2):432-433 View PubMed Thanarajasingam G, Thanarajasingam U, Ansell SM. Immune checkpoint blockade in lymphoid malignancies. FEBS J. 2016 Jun; 283 (12):2233-44 Epub 2016 Feb 22 View PubMed Thanarajasingam U, Niewold TB. Sirukumab : a novel therapy for lupus nephritis? Expert Opin Investig Drugs. 2014 Oct; 23 (10):1449-55 Epub 2014 Sept 05 View PubMed Eaton JE, Reed DA, Aboff BM, Call SA, Chelminski PR, Thanarajasingam U, Post JA, Thomas KG, Dupras DM, Beckman TJ, West CP, Wittich CM, Halvorsen AJ, McDonald FS. Update in internal medicine residency education: a review of the literature in 2010 and 2011. J Grad Med Educ. 2013 Jun; 5 (2):203-10 View PubMed Higgins JV, Thanarajasingam U, Osborn TG. A unique case of relapsing polychondritis presenting with acute pericarditis. Case Rep Rheumatol. 2013; 2013:287592 Epub 2013 Dec 17 View PubMed Thanarajasingam U, McDonald FS, Halvorsen AJ, Naessens JM, Cabanela RL, Johnson MG, Daniels PR, Williams AW, Reed DA. Service census caps and unit-based admissions: resident workload, conference attendance, duty hour compliance, and patient safety. Mayo Clin Proc. 2012 Apr; 87 (4):320-7 View PubMed Qian Q, Thanarajasingam U, Oeckler RA, Sawyer MD, Sethi S, Edwards WD. Expanded spectrum of antineutrophil cytoplasmic antibody-negative vasculitis involving vessels from capillaries to medium-sized arteries. Arthritis Care Res (Hoboken). 2011 Nov; 63(11):1634-8. View PubMed Thanarajasingam U, Larson SA, Francis DL. Wegener's granulomatosis presenting with colonic ulcerations. Clin Gastroenterol Hepatol. 2011 Mar; 9(3):A22. Epub 2010 Oct 15. View PubMed Thanarajasingam U, Chen B, Tortorelli CL, Jakub JW, Ghosh K. Diabetic mastopathy as a radiographically occult palpable breast mass. Case Rep Med. 2011; 2011:162350 Epub 2011 Nov 03 View PubMed Galivo F, Diaz RM, Thanarajasingam U, Jevremovic D, Wongthida P, Thompson J, Kottke T, Barber GN, Melcher A, Vile RG. Interference of CD40L-mediated tumor immunotherapy by oncolytic vesicular stomatitis virus. Hum Gene Ther. 2010 Apr; 21 (4):439-50 View PubMed Sanchez-Perez L, Gough M, Qiao J, Thanarajasingam U, Kottke T, Ahmed A, Thompson JM, Maria Diaz R, Vile RG. Synergy of adoptive T-cell therapy and intratumoral suicide gene therapy is mediated by host NK cells. Gene Ther. 2007 Jul; 14 (13):998-1009 Epub 2007 Apr 19 View PubMed Thanarajasingam U, Sanz L, Diaz R, Qiao J, Sanchez-Perez L, Kottke T, Thompson J, Chester J, Vile RG. Delivery of CCL21 to metastatic disease improves the efficacy of adoptive T-cell therapy. Cancer Res. 2007 Jan 1; 67 (1):300-8 View PubMed Gough M, Crittenden M, Thanarajasingam U, Sanchez-Perez L, Thompson J, Jevremovic D, Vile R. Gene therapy to manipulate effector T cell trafficking to tumors for immunotherapy. J Immunol. 2005 May 1; 174 (9):5766-73 View PubMed Crittenden MR, Thanarajasingam U, Vile RG, Gough MJ. Intratumoral immunotherapy: using the tumour against itself. Immunology. 2005 Jan; 114 (1):11-22 View PubMed Smith JS, Tachibana I, Pohl U, Lee HK, Thanarajasingam U, Portier BP, Ueki K, Ramaswamy S, Billings SJ, Mohrenweiser HW, Louis DN, Jenkins RB. A transcript map of the chromosome 19q-arm glioma tumor suppressor region. Genomics. 2000 Feb 15; 64 (1):44-50 View PubMed PST-20216437 Home Publications